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Dasatinib as first-line treatment for adult patients with Philadelphia chromosome–positive acute lymphoblastic leukemia
Bone microstructural changes revealed by high-resolution peripheral quantitative computed tomography imaging and elevated DKK1 and MIP-1α levels in patients with MGUS
General population low-count CLL-like MBL persists over time without clinical progression, although carrying the same cytogenetic abnormalities of CLL
No difference in outcome between children and adolescents transplanted for acute lymphoblastic leukemia in second remission
Donor-specific anti-HLA antibodies predict outcome in double umbilical cord blood transplantation
Issue Archive
December 15 2011
In this Issue
Table of Contents
Inside Blood
Blood Work
Plenary Paper
Review Articles
Clinical Trials and Observations
Dasatinib as first-line treatment for adult patients with Philadelphia chromosome–positive acute lymphoblastic leukemia
Clinical Trials & Observations
Robin Foà,Antonella Vitale,Marco Vignetti,Giovanna Meloni,Anna Guarini,Maria Stefania De Propris,Loredana Elia,Francesca Paoloni,Paola Fazi,Giuseppe Cimino,Francesco Nobile,Felicetto Ferrara,Carlo Castagnola,Simona Sica,Pietro Leoni,Eliana Zuffa,Claudio Fozza,Mario Luppi,Anna Candoni,Ilaria Iacobucci,Simona Soverini,Franco Mandelli,Giovanni Martinelli,Michele Baccarani,on behalf of the GIMEMA Acute Leukemia Working Party
Bone microstructural changes revealed by high-resolution peripheral quantitative computed tomography imaging and elevated DKK1 and MIP-1α levels in patients with MGUS
Clinical Trials & Observations
Alvin C. Ng,Sundeep Khosla,Natthinee Charatcharoenwitthaya,Shaji K. Kumar,Sara J. Achenbach,Margaret F. Holets,Louise K. McCready,L. Joseph Melton, III,Robert A. Kyle,S. Vincent Rajkumar,Matthew T. Drake
General population low-count CLL-like MBL persists over time without clinical progression, although carrying the same cytogenetic abnormalities of CLL
Clinical Trials & Observations
Claudia Fazi,Lydia Scarfò,Lorenza Pecciarini,Francesca Cottini,Antonis Dagklis,Agnieszka Janus,Anna Talarico,Cristina Scielzo,Cinzia Sala,Daniela Toniolo,Federico Caligaris-Cappio,Paolo Ghia
Hematopoiesis and Stem Cells
The ability of MLL to bind RUNX1 and methylate H3K4 at PU.1 regulatory regions is impaired by MDS/AML-associated RUNX1/AML1 mutations
Gang Huang,Xinghui Zhao,Lan Wang,Shannon Elf,Hao Xu,Xinyang Zhao,Goro Sashida,Yue Zhang,Yan Liu,Jennifer Lee,Silvia Menendez,Youyang Yang,Xiaomei Yan,Pu Zhang,Daniel G. Tenen,Motomi Osato,James J.-D. Hsieh,Stephen D. Nimer
Immunobiology
Frequent loss of HLA alleles associated with copy number-neutral 6pLOH in acquired aplastic anemia
Takamasa Katagiri,Aiko Sato-Otsubo,Koichi Kashiwase,Satoko Morishima,Yusuke Sato,Yuka Mori,Motohiro Kato,Masashi Sanada,Yasuo Morishima,Kohei Hosokawa,Yumi Sasaki,Shigeki Ohtake,Seishi Ogawa,Shinji Nakao,on behalf of the Japan Marrow Donor Program
Lymphoid Neoplasia
Myeloid Neoplasia
AML1/RUNX1 functions as a cytoplasmic attenuator of NF-κB signaling in the repression of myeloid tumors
Masahiro Nakagawa,Munetake Shimabe,Naoko Watanabe-Okochi,Shunya Arai,Akihide Yoshimi,Akihito Shinohara,Nahoko Nishimoto,Keisuke Kataoka,Tomohiko Sato,Keiki Kumano,Yasuhito Nannya,Motoshi Ichikawa,Yoichi Imai,Mineo Kurokawa
Phagocytes, Granulocytes, and Myelopoiesis
Red Cells, Iron, and Erythropoiesis
A novel type of congenital hypochromic anemia associated with a nonsense mutation in the STEAP3/TSAP6 gene
Bernard Grandchamp,Gilles Hetet,Caroline Kannengiesser,Claire Oudin,Carole Beaumont,Sylvie Rodrigues-Ferreira,Robert Amson,Adam Telerman,Peter Nielsen,Elisabeth Kohne,Christina Balser,Hermann Heimpel
Thrombosis and Hemostasis
Transfusion Medicine
Transfusion of human volunteers with older, stored red blood cells produces extravascular hemolysis and circulating non–transferrin-bound iron
Eldad A. Hod,Gary M. Brittenham,Genia B. Billote,Richard O. Francis,Yelena Z. Ginzburg,Jeanne E. Hendrickson,Jeffrey Jhang,Joseph Schwartz,Shruti Sharma,Sujit Sheth,Anthony N. Sireci,Hannah L. Stephens,Brie A. Stotler,Boguslaw S. Wojczyk,James C. Zimring,Steven L. Spitalnik
Transplantation
No difference in outcome between children and adolescents transplanted for acute lymphoblastic leukemia in second remission
Clinical Trials & Observations
Giorgio Dini,Marco Zecca,Adriana Balduzzi,Chiara Messina,Riccardo Masetti,Franca Fagioli,Claudio Favre,Marco Rabusin,Fulvio Porta,Erika Biral,Mimmo Ripaldi,Anna Paola Iori,Carla Rognoni,Arcangelo Prete,Franco Locatelli,on behalf of the Associazione Italiana Ematologia ed Oncologia Pediatrica–Hematopoietic Stem Cell Transplantation (AIEOP-HSCT) Group
Donor-specific anti-HLA antibodies predict outcome in double umbilical cord blood transplantation
Clinical Trials & Observations
Corey Cutler,Haesook T. Kim,Lixian Sun,Doreen Sese,Brett Glotzbecker,Philippe Armand,John Koreth,Vincent Ho,Edwin Alyea,Karen Ballen,Jerome Ritz,Robert J. Soiffer,Edgar Milford,Joseph H. Antin
Regenerating islet-derived 3-alpha is a biomarker of gastrointestinal graft-versus-host disease
James L. M. Ferrara,Andrew C. Harris,Joel K. Greenson,Thomas M. Braun,Ernst Holler,Takanori Teshima,John E. Levine,Sung W. J. Choi,Elisabeth Huber,Karin Landfried,Koichi Akashi,Mark Vander Lugt,Pavan Reddy,Alice Chin,Qing Zhang,Samir Hanash,Sophie Paczesny
Vascular Biology
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Cover Image
Cover Image
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Interaction between a human mature DC and an autologous resting NK cell. Cells interacting for 20 minutes were fixed and stained with antibodies to actin and tubulin. In this image, actin staining is pseudocolored hot green and tubulin hot red. DAPI staining is represented in blue. See the article by Barreira da Silva et al on page 6487.
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