Issue Archive
Table of Contents
INSIDE BLOOD
REVIEW ARTICLES
CLINICAL TRIALS AND OBSERVATIONS
Oral 6-mercaptopurine versus oral 6-thioguanine and veno-occlusive disease in children with standard-risk acute lymphoblastic leukemia: report of the Children's Oncology Group CCG-1952 clinical trial
Clinical Trials & Observations
Distinct clinical and biologic characteristics in adult acute myeloid leukemia bearing the isocitrate dehydrogenase 1 mutation
Clinical Trials & Observations
Dexamethasone plus rituximab yields higher sustained response rates than dexamethasone monotherapy in adults with primary immune thrombocytopenia
Clinical Trials & Observations
Prognostic role of PET scanning before and after reduced-intensity allogeneic stem cell transplantation for lymphoma
Clinical Trials & Observations
HEMATOPOIESIS AND STEM CELLS
IMMUNOBIOLOGY
LYMPHOID NEOPLASIA
The sumoylation pathway is dysregulated in multiple myeloma and is associated with adverse patient outcome
Inactivation of LEF1 in T-cell acute lymphoblastic leukemia
MYELOID NEOPLASIA
Hes1 immortalizes committed progenitors and plays a role in blast crisis transition in chronic myelogenous leukemia
Prevalence and prognostic impact of allelic imbalances associated with leukemic transformation of Philadelphia chromosome–negative myeloproliferative neoplasms
Two routes to leukemic transformation after a JAK2 mutation–positive myeloproliferative neoplasm
Apoptosis induced by JAK2 inhibition is mediated by Bim and enhanced by the BH3 mimetic ABT-737 in JAK2 mutant human erythroid cells
Efficacy of the JAK2 inhibitor INCB16562 in a murine model of MPLW515L-induced thrombocytosis and myelofibrosis
PLATELETS AND THROMBOPOIESIS
RED CELLS, IRON, AND ERYTHROPOIESIS
TRANSPLANTATION
Effective and long-term control of EBV PTLD after transfer of peptide-selected T cells
VASCULAR BIOLOGY
CORRESPONDENCE
RETRACTIONS
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Cover Image
Cover Image
Osteoclasts are the cells responsible for bone resorption and are derived from hematopoietic stem cells. The cover shows an image of an osteoclast generated on a mineralized dentine substrate by directed differentiation of human-induced pluripotent stem cells through a defined sequence of mesoderm induction, hematopoiesis specification, myeloid cell expansion, and differentiation to osteoclasts. The confocal image depicts the osteoclast associated with a resorption pit (not shown) expressing the marker protein β3 integrin (green), formation of an F-actin ring (red), and secretion the cysteine protease cathepsin K (blue), which are characteristic features of actively resorbing osteoclasts. See the article by Grigoriadis et al on page 2769.
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