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Journal Articles

The BET Inhibitor, CPI-0610, Promotes Myeloid Differentiation in Myelofibrosis Patient Bone Marrow and Peripheral CD34+ Hematopoietic Stem Cells

Jennifer A Mertz, PhD, Patricia J Keller, PhD, Rosana D Meyer, MD, Oksana Zavidij, PhD, Jike Cui, PhD, Jean-Jacques Kiladjian, MD PhD, Srdan Verstovsek, MD PhD, Vikas Gupta, MD FRCP, FRCPath, Moshe Talpaz, MD, Claire Harrison, DM, FRCP, FRCPath, Adam J. Mead, MD PhD, Ruben Mesa, MD, John Mascarenhas, MD, Adrian Senderowicz, MD, Gozde Colak, PhD, James Shao, MS, Katarina Luptakova, MD, Jeffrey S Humphrey, MD, Jing Wang, PhD, Patrick Trojer, PhD, Mohamed E Salama, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 37–38.
https://doi.org/10.1182/blood-2020-138752
Published: 2020
Journal Articles

MANIFEST-2, a Global, Phase 3, Randomized, Double-Blind, Active-Control Study of CPI-0610 and Ruxolitinib Vs. Placebo and Ruxolitinib in JAK-Inhibitor-Naive Myelofibrosis Patients

John Mascarenhas, MD, Claire Harrison, DM, FRCP, FRCPath, Katarina Luptakova, MD, Jessica Christo, MA, Jing Wang, PhD, Jennifer A Mertz, PhD, Gozde Colak, PhD, James Shao, MS, Suresh Bobba, MD, Patrick Trojer, PhD, Adrian Senderowicz, MD, Jeffrey S Humphrey, MD, Srdan Verstovsek, MD PhD
Journal: Blood
Blood (2020) 136 (Supplement 1): 43.
https://doi.org/10.1182/blood-2020-140901
Published: 2020
Journal Articles

Dreamm-5: Platform Trial Evaluating Belantamab Mafodotin (a BCMA-directed Immuno-conjugate) in Combination with Novel Agents in Relapsed or Refractory Multiple Myeloma (RRMM)

Paul G. Richardson, MD, Swethajit Biswas, Beata Holkova, Nicola Jackson, Thelma Netherway, Weichao Bao, Geraldine Ferron-Brady, Anne Yeakey, Chris Shelton, Rocio Montes De Oca, PhD, Chris Ahlers, Sonia Franco, Marc Ballas, Elaine Paul, Katarina Luptakova, Ira Gupta, Joanna Opalinska
Journal: Blood
Blood (2019) 134 (Supplement_1): 1857.
https://doi.org/10.1182/blood-2019-129879
Published: 2019
Journal Articles

Real-World and Clinical Trial Data in Relapsed/Refractory Multiple Myeloma (RRMM): Evaluating Treatment Duration and Comparing Effectiveness and Efficacy

Paul G Richardson, MD, Jesus F. San Miguel, MD, Philippe Moreau, MDPhD, Roman Hajek, Meletios A. Dimopoulos, Antonio Palumbo, MD, Katarina Luptakova, MD, Tomas Skacel, MD, Shaji K Kumar, MD, Kenneth C Anderson, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3149.
https://doi.org/10.1182/blood.V130.Suppl_1.3149.3149
Published: 2017
Journal Articles

Duration of Therapy (DOT) and Time to Next Therapy (TTNT) of Bortezomib, Carfilzomib and Ixazomib Combinations with Lenalidomide/Dexamethasone (VRd, KRd, IRd) in Patients (pts) with Relapsed/Refractory Multiple Myeloma (RRMM): Clinical Practice in the United States Vs Clinical Trial Experience

Ajai Chari, MD, Dorothy Romanus, Katarina Luptakova, MD, Aditya Raju, MS, Eileen Farrelly, MPH, Marlo Blazer, PharmD, Tomas Skacel, MD, Parameswaran Hari, MD MRCP, MS
Journal: Blood
Blood (2017) 130 (Supplement 1): 1818.
https://doi.org/10.1182/blood.V130.Suppl_1.1818.1818
Published: 2017
Journal Articles

Uncovering the Blind Spot of Clinical Trials: First Report of Baseline Characteristics of Newly Diagnosed (ND) and Relapsed/Refractory (RR) Multiple Myeloma (MM) Patients (Pts) in Insight-MM, a Global, Prospective, Observational Study

Evangelos Terpos, MD PhD, Ajai Chari, MD, Robert M Rifkin, MD, Rafat Abonour, MD, Jesus G. Berdeja, MD, Mario Boccadoro, Gordon Cook, MD PhD, Caitlin Costello, MD, Saulius Girnius, MD, Hartmut Goldschmidt, MD, Roman Hájek, MD, Vania T M Hungria, MD PhD, Hans C. Lee, MD, Xavier Leleu, MD PhD, Jim Omel, MD, Andrew Spencer, MD, Michael A Thompson, MD, Saad Z Usmani, MD, Jorge Vela-Ojeda, MD PhD, Jeffrey A Zonder, MD, Liviu Niculescu, MD, Stephen Noga, MD, Tomas Skacel, MD, Roxanne Cacioppo, Brittany Sickler, BA, BS, Shawn Yu, Kaili Ren, PhD, Katarina Luptakova, MD, Dawn Marie Stull, Faith E. Davies, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 5419.
https://doi.org/10.1182/blood.V130.Suppl_1.5419.5419
Published: 2017
Journal Articles

Treatment Patterns and Clinical Outcomes Among Patients with Newly Diagnosed and Relapsed/Refractory Systemic Light Chain Amyloidosis

Huamao Mark Lin, PhD, Carl Victor Asche, MBA, MSc, PhD, Jinma Ren, PhD, Candice Yong, PhD, Hari Parameswaran, MD, Katarina Luptakova, Douglas Faller, MD, Brian Seal, RPh, MBA, PhD
Journal: Blood
Blood (2016) 128 (22): 3559.
https://doi.org/10.1182/blood.V128.22.3559.3559
Published: 2016
Journal Articles

Higher c-MYC Expression Is Associated with Ixazomib-Lenalidomide-Dexamethasone (IRd) Progression-Free Survival (PFS) Benefit Versus Placebo-Rd: Biomarker Analysis of the Phase 3 Tourmaline-MM1 Study in Relapsed/Refractory Multiple Myeloma (RRMM)

Alessandra Di Bacco, PhD, Nizar J. Bahlis, MD, Nikhil C Munshi, MD, Hervé Avet-Loiseau, MD PhD, Tamás Masszi, MD, Luísa Viterbo, MD, Ludek Pour, MD PhD, Peter Ganly, BMBCh, PhD, Michele Cavo, MD, Christian Langer, MD, Shaji Kumar, MD, S. Vincent Rajkumar, MD, Deborah Berg, RN, MSN, Jianchang Lin, PhD, Bin Li, Sunita Badola, Lei Shen, Jacob Zhang, Ling Wang, PhD, Dixie-Lee Esseltine, MD, Katarina Luptakova, Helgi van de Velde, MD PhD, Paul G. Richardson, MD, Philippe Moreau
Journal: Blood
Blood (2016) 128 (22): 243.
https://doi.org/10.1182/blood.V128.22.243.243
Published: 2016
Journal Articles

A Real-World Evidence Systematic Literature Review of Health-Related Quality of Life, Costs and Economic Evaluations in Newly-Diagnosed Multiple Myeloma Patients

Candice Yong, PhD, Ellen Korol, MSc, Zaeem Khan, MPh, Huamao Mark Lin, PhD, Juliette Thompson, Veronika Valovicova, MSc, Katarina Luptakova, Brian Seal, RPh, MBA, PhD
Journal: Blood
Blood (2016) 128 (22): 4777.
https://doi.org/10.1182/blood.V128.22.4777.4777
Published: 2016
Journal Articles

Real-World Clinical Outcomes By Cytogenetic Risk Category in Relapsed or Refractory Multiple Myeloma: Evidence from a Cohort Review in France

Huamao Mark Lin, PhD, Keith L Davis, MA, James A. Kaye, MD DrPH, Katarina Luptakova, Lu Gao, PhD(candidate), Saurabh Nagar, MS, Brian Seal, RPh, MBA, PhD, Mohamad Mohty, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4784.
https://doi.org/10.1182/blood.V128.22.4784.4784
Published: 2016
Journal Articles

Real-World Treatment Patterns and Health Care Resource Utilization in Relapsed or Refractory Multiple Myeloma: Evidence from a Cohort Review in France

Huamao Mark Lin, PhD, Keith L Davis, MA, James A. Kaye, MD DrPH, Katarina Luptakova, Lu Gao, PhD(candidate), Saurabh Nagar, MS, Brian Seal, RPh, MBA, PhD, Mohamad Mohty, MD PhD
Journal: Blood
Blood (2016) 128 (22): 5945.
https://doi.org/10.1182/blood.V128.22.5945.5945
Published: 2016
Journal Articles

Real-World Treatment Patterns in Relapsed or Refractory Multiple Myeloma: Evidence from a Cohort Review in the United Kingdom

Huamao Mark Lin, PhD, Keith L Davis, MA, James A. Kaye, MD DrPH, Katarina Luptakova, Saurabh Nagar, MS, Brian Seal, RPh, MBA, PhD
Journal: Blood
Blood (2016) 128 (22): 5947.
https://doi.org/10.1182/blood.V128.22.5947.5947
Published: 2016
Journal Articles

Patient Characteristics, Treatment Patterns and Outcomes Among Relapsed/Refractory Multiple Myeloma (RRMM) Patients in Japan

Gyungjin Jun, MS, Katarina Luptakova, Hiroo Koizumi, Kosuke Iwasaki, F.I.A.J., M.A.A.A., M.B.A., Shinzo Hiroi, Junpei Soeda, MD PhD
Journal: Blood
Blood (2016) 128 (22): 5950.
https://doi.org/10.1182/blood.V128.22.5950.5950
Published: 2016
Journal Articles

Global, Prospective, Non-Interventional, Observational Study of Presentation, Treatment Patterns, and Outcomes in Multiple Myeloma Patients: The Insight-MM Study

Robert M Rifkin, Faith E Davies, MD, Antonio Palumbo, MD, Jeffrey Zonder, MD, Saulius K Girnius, MD, Caitlin L Costello, MD, Saad Z Usmani, MD FACP, Jesus G. Berdeja, MD, Jim Omel, Michael A Thompson, MD PhD, Jatin Shah, MD, J Sanford Schwartz, Roman Hajek, MD, Evangelos Terpos, MD PhD, Vânia Hungria, MD PhD, Maria-Victoria Mateos, MD PhD, Gordon Cook, Xavier Leleu, Andrew Spencer, Hartmut Goldschmidt, MD, Brian Seal, RPh, MBA, PhD, Chris L Pashos, PhD, Dawn Marie Stull, PharmD, FRACP, Dorothy Romanus, RPh, MSc, PhD, Roxanne Cacioppo, Jill A Bell, PhD, Shawn Yu, Katarina Luptakova, Liviu Niculescu, MD PhD, Stephen J Noga, Tomas Skacel, Ajai Chari, MD
Journal: Blood
Blood (2016) 128 (22): 5681.
https://doi.org/10.1182/blood.V128.22.5681.5681
Published: 2016
Journal Articles

Longer Time to Best Response and Depth of Response Are Associated with Improved Duration of Best Achieved Response and Progression-Free Survival (PFS): Post-Hoc Analysis of Phase 3 Tourmaline-MM1 Trial in Relapsed/Refractory Multiple Myeloma (RRMM)

Laurent Garderet, MD PhD, Jacob P. Laubach, MD, Anne-Marie Stoppa, MD, Parameswaran Hari, MD MRCP, MS, Michele Cavo, MD, Heinz Ludwig, MD, Maria-Victoria Mateos, MD PhD, Katarina Luptakova, Jianchang Lin, PhD, Helgi van de Velde, MD PhD, Deborah Berg, RN, MSN, Philippe Moreau, Paul G. Richardson, MD
Journal: Blood
Blood (2016) 128 (22): 2134.
https://doi.org/10.1182/blood.V128.22.2134.2134
Published: 2016
Journal Articles

MUC-1 Regulates MiR34a Expression in Acute Myeloid Leukemia Cells Resulting in an Accumulation of Granulocytic Myeloid-Derived Suppressor Cells

Athalia Rachel Pyzer, MD, Dina Stroopinsky, PhD, Hasan Rajabi, PhD, Jacalyn Rosenblatt, MD, Maxwell Douglas Coll, Salvia Jain, MD, Kristen Anna Palmer, Ashujit Tagde, PhD BPharm, Katarina Luptakova, MD, Malgorzata McMasters, MD, James D. Levine, MD, Robin Joyce, MD, Jon E. Arnason, MD, Myrna Rita Nahas, MD, Rebecca Karp Leaf, MD, Abigail Washington, Michal Bar-Natan, MD, Poorvi Somaiya Dutt, Donald Küfe, MD, David Avigan, MD
Journal: Blood
Blood (2015) 126 (23): 643.
https://doi.org/10.1182/blood.V126.23.643.643
Published: 2015
Journal Articles

Blockade of PD-1 in Combination with Dendritic Cell/Myeloma Fusion Cell Vaccination Following Autologous Stem Cell Transplantation Is Well Tolerated, Induces Anti-Tumor Immunity and May Lead to Eradication of Measureable Disease

Jacalyn Rosenblatt, MD, Irit Avivi, MD, Noam Binyamini, MD, Lynne Uhl, MD, Poorvi Somaiya, Dina Stroopinsky, PhD, Kristen Anna Palmer, Maxwell Douglas Coll, Tami Katz, PhD, Lina Bisharat, MSc, Robin Joyce, MD, James D. Levine, MD, Jon E. Arnason, MD, Katarina Luptakova, MD, Malgorzata McMasters, MD, Salvia Jain, MD, Merav Leiba, MD, Aya Sato-Dilorenzo, RN, BSN, OCN, Emma Logan, Mary Paty Bryant, Viki Held, Paul G. Richardson, MD, Jacob P. Laubach, MD, Arnon Nagler, MD MSc, Kenneth C. Anderson, MD, Nikhil C. Munshi, MD, Jacob M. Rowe, MD, Donald Kufe, MD, David Avigan, MD
Journal: Blood
Blood (2015) 126 (23): 4218.
https://doi.org/10.1182/blood.V126.23.4218.4218
Published: 2015
Journal Articles

DC/Aml Fusion Cell Vaccination Administered to AML Patients Who Achieve a Complete Remission Potently Expands Leukemia Reactive T Cells and Is Associated with Durable Remissions

Jacalyn Rosenblatt, MD, Richard M. Stone, MD, Lynne Uhl, MD, Donna Neuberg, ScD, Poorvi Somaiya, Dina Stroopinsky, PhD, Robin Joyce, MD, James D. Levine, MD, Jon E. Arnason, MD, Katarina Luptakova, MD, Malgorzata McMasters, MD, Salvia Jain, MD, David P. Steensma, MD, Daniel J. DeAngelo, MD PhD, Ilene Galinsky, ANP, Aya Sato-Dilorenzo, RN, BSN, OCN, Kristen Anna Palmer, Emma Logan, Mary Paty Bryant, Donald Kufe, MD, David Avigan, MD
Journal: Blood
Blood (2015) 126 (23): 2549.
https://doi.org/10.1182/blood.V126.23.2549.2549
Published: 2015
Journal Articles

A Phase 1 Study of Lenalidomide in Combination with Mitoxantrone, Etoposide, and Ara-C in Patients with Relapsed or Refractory Acute Myeloid Leukemia

Daniel J. DeAngelo, MD PhD, Amir T. Fathi, MD, Lillian Werner, David Avigan, MD, Katarina Luptakova, MD, Martha Wadleigh, MD, David P. Steensma, MD, Gabriela Soriano Hobbs, MD, Eyal C. Attar, MD, Philip C. Amrein, MD, Richard M. Stone, MD, Karen K. Ballen, MD
Journal: Blood
Blood (2015) 126 (23): 2550.
https://doi.org/10.1182/blood.V126.23.2550.2550
Published: 2015
Journal Articles

MUC1 Inhibition Overcomes Chemotherapy Resistance in Acute Myeloid Leukemia

Myrna Rita Nahas, MD, Dina Stroopinsky, PhD, Hasan Rajabi, PhD, Ashujit Tagde, PhD, Athalia Rachel Pyzer, MD, Salvia Jain, MD, Maxwell Douglas Coll, Michal Bar-Natan, MD, Rebecca Karp, MD, Katarina Luptakova, MD, Kristen Anna Palmer, Poorvi Somaiya, Jon Arnason, MD, Malgorzata McMasters, MD, Robin Joyce, MD, James D. Levine, MD, Donald Kufe, MD, David Avigan, MD, Jacalyn Rosenblatt
Journal: Blood
Blood (2015) 126 (23): 2473.
https://doi.org/10.1182/blood.V126.23.2473.2473
Published: 2015