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Ulrich Steidl
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Journal Articles

Elevated Clonal Hematopoiesis in Environmentally Exposed Responders Has Distinct Age-Related Patterns and Relies on IL1RAP for Clonal Expansion

Divij Verma, Rachel Zeig Owens, David G Goldfarb, Kith Pradhan, Srabani Sahu, Susheian Kelly, Orsi Giricz, Sakshi Jasra, Yiyu Zou, Colette Prophete, Lidiane Torres, Srinivas Aluri, Samarpana Chakraborty, Shanisha Gordon Mitchell, Rajni Kumari, Jingli Wang, Alexander J Silver, Charles Hall, Ryan Bender, Ola Landgren, Lee Greenberger, Advaitha Madireddy, Aditi Shastri, Lindsay Lafave, Anna Nolan, Michael R. Savona, Ulrich Steidl, David Prezant, Amit Verma
Journal: Blood
Blood (2024) 144 (Supplement 1): 943.
https://doi.org/10.1182/blood-2024-194127
Published: 2024
Journal Articles

TGF-β1-SMAD2 Axis Regulates Hematopoiesis and β-Globin Gene Expression Via Super-Enhancer Associated Chromatin Reorganization

Srinivas Aluri, Kimo Bachiashvili, Anjali Budhathoki, Jong J Jeong, Shanisha Gordon Mitchell, Milagros Carbajal, Samarpana Chakraborty, Sanjay Pandey, Mahinder Paul Wadhwa, Srabani Sahu, Jung-In Yang, Gaurav S Choudhary, Tushar Damodar Bhagat, Nandini Ramachandra, Rongbao Zhao, Bianca Rivera, Ritesh Aggarwal, Kith Pradhan, Shahina Maqbool, Seong jin Kim, Sunjin Hwang, Ulrich Steidl, Aditi Shastri, Marc Raaijmakers, Andrea Pellagatti, Jacqueline Boultwood, Amittha Wickrema, Amit Verma
Journal: Blood
Blood (2024) 144 (Supplement 1): 878.
https://doi.org/10.1182/blood-2024-201101
Published: 2024
Journal Articles

Transient Inflammatory Signals Drive Persistent Changes in the PU.1 Transcriptional State of HSC

Justin C. Wheat, Ulrich Steidl
Journal: Blood
Blood (2024) 144 (Supplement 1): 4044.
https://doi.org/10.1182/blood-2024-208667
Published: 2024
Journal Articles

Post-Transplantation Cyclophosphamide and Abatacept Graft-Versus-Host-Disease Prophylaxis Shows Improved Outcomes in North American Adult T-Cell Leukemia/Lymphoma

Julie Nguyen, Abdul-Hamid Bazarbachi, Kith Pradhan, John Yan, Emma Cordover, Daniel K Reef, Riya Patel, Rama Al Hamed, Astha Thakkar, Shafia Rahman, Diego Adrianzen Herrera, Ryann Quinn, Alyssa de Castro, Kailyn Gillick, Jennat Mustafa, Fariha Khatun, Amanda Lombardo, Latoya S Townsend, Michelly Abreu, Nicole Chambers, Richard Elkind, Yang Shi, Yanhua Wang, Olga Derman, Kira Gritsman, Ulrich Steidl, Mendel Goldfinger, Noah Kornblum, Aditi Shastri, Ioannis Mantzaris, Lizamarie Bachier Rodriguez, Brittany Moavero, Jhannine Verceles, Angela Czavar, Lauren Shapiro, Trent Wang, Juan Carlos Ramos, Nishi Shah, Ridhi Gupta, Marina Konopleva, Ira Braunschweig, Amit Verma, B. Hilda Ye, Murali Janakiram, Dennis L Cooper, R. Alejandro Sica
Journal: Blood
Blood (2024) 144 (Supplement 1): 7367.
https://doi.org/10.1182/blood-2024-207521
Published: 2024
Journal Articles

A Phase 1 Study Investigating the Safety and Efficacy of Danvatirsen As Monotherapy Followed By Combination with Venetoclax in Patients with Relapsed/Refractory MDS and AML

Aditi Shastri, Mendel Goldfinger, Ioannis Mantzaris, Guillermo Garcia-Manero, Tapan M. Kadia, Jing Ning, Balda Tirone, Rikin Gandhi, Farhad Ravandi, Naveen Pemmaraju, Guillermo Montalban-Bravo, Annemarie Munoz, Michelle Golez, Lianchun Xiao, Kith Pradhan, Karen Fehn, Lamisha Shah, Hui Zhang, Samarpana Chakraborty, Eric J. Feldman, Nicholas J. Short, Jayastu Senapati, Dennis L Cooper, Alejandro Sica, Noah Kornblum, Lauren Shapiro, Nishi Shah, Susan MacIntyre, Ulrich Steidl, Amit Verma, Kira Gritsman, Andrew Denker, Marina Konopleva, Naval Daver
Journal: Blood
Blood (2024) 144 (Supplement 1): 4265.5.
https://doi.org/10.1182/blood-2024-208998
Published: 2024
Journal Articles

Degrading SMARCA2/4 Relieves the Differentiation Block in AML Via Chromatin Alterations Affecting S100A8/9

Sarah Aminov, Rongbao Zhao, Kith Pradhan, Srabani Sahu, Rahul Sanawar, Shanisha Gordon Mitchell, Emma Rabinovich, Ariel Fromowitz, Joyeeta Chakraborty, Srinivas Aluri, Nayem Haque, Milagros Carbajal, Aditi Shastri, Ulrich Steidl, Susanta Samajdar, Akhil Kumar, Murali Ramachandra, Kristy Stengel, Robert Coleman, Amit Verma
Journal: Blood
Blood (2024) 144 (Supplement 1): 2909.
https://doi.org/10.1182/blood-2024-198479
Published: 2024
Journal Articles

Heparan sulfates and heparan sulfate proteoglycans in hematopoiesis

Richard T. Piszczatowski, Hannes E. Bülow, Ulrich Steidl
Journal: Blood
Blood (2024) 143 (25): 2571–2587.
https://doi.org/10.1182/blood.2023022736
Published: 2024
Journal Articles

Venetoclax Combined with “7+3” Induction Chemotherapy Induces High Rates of MRD-Negative Remission in Newly Diagnosed AML Patients Fit for Intensive Chemotherapy Irrespective of Age

Ioannis Mantzaris, Mendel Goldfinger, Nishi Shah, Annemarie Munoz, Aradhika Dhawan, Nicole Chambers, Karen Fehn, Joel Victor, Aditi Shastri, Kira Gritsman, Noah Kornblum, Alejandro Sica, Dennis L Cooper, Amit Verma, Mimi Kim, Ulrich Steidl, Eric J Feldman, Marina Y. Konopleva
Journal: Blood
Blood (2023) 142 (Supplement 1): 4257.
https://doi.org/10.1182/blood-2023-188176
Published: 2023
Journal Articles

GDF11/SMAD Regulated Splicing of GATA1 Is Associated with Response to Luspatercept in Lower-Risk Myelodysplastic Syndromes (LR-MDS)

Srinivas Aluri, Ellen Fraint, Samarpana Chakraborty, Aarif Ahsan, Gowri Poigailwar, Rongbao Zhao, Kith Pradhan, Kimo Bachiashvili, Anjali Budhathoki, Beamon Agarwal, Shanisha Gordon Mitchell, Milagros Carbajal, Srabani Sahu, Jacqueline Boultwood, Andrea Pellagatti, Ulrich Steidl, Amittha Wickrema, Satish Nandakumar, Aditi Shastri, Teresa Bowman, Sadanand Vodala, Amit K. Verma
Journal: Blood
Blood (2023) 142 (Supplement 1): 318.
https://doi.org/10.1182/blood-2023-179131
Published: 2023
Journal Articles

Novel Clinically Useful Inhibitor of Mediator Complex, RVU120, Relives Differentiation Block in MDS/AML

Opeyemi Ajibade, Urszula Pakulska, Emma Rabinovich, Ariel Fromowitz, Srabani Sahu, Sarah Aminov, Nandini Ramachandra, Srinivas Aluri, Shanisha Gordon Mitchell, Milagros Carbajal, Kinga Keska-Izworska, Michał Combik, Marta Obacz, Elżbieta Adamczyk, Jan M. Zaucha, Ewa Zarzycka, Przemyslaw Juszczynski, Jacqueline Boultwood, Andrea Pellagatti, Kith Pradhan, Ulrich Steidl, Aditi Shastri, Rongbao Zhao, Milena Mazan, Tomasz Rzymski, Amit Verma
Journal: Blood
Blood (2023) 142 (Supplement 1): 3225.
https://doi.org/10.1182/blood-2023-186227
Published: 2023
Journal Articles

The Dual Inflammasome/Myddosome Inhibitor HT-6184 Restores Erythropoiesis in MDS/AML

Emma Rabinovich, Ariel Fromowitz, Opeyemi Ajibade, Srabani Sahu, Divij Verma, Sarah Aminov, Nandini Ramachandra, Christopher Selverian, Nailya Khalizova, Srinivas Aluri, Rahul Sanawar, Shanisha Gordon Mitchell, Milagros Carbajal, Jacqueline Boultwood, Andrea Pellagatti, Ulrich Steidl, Aditi Shastri, Rongbao Zhao, Alexis Mollard, Margit Janat-Amsbury, David J. Bearss, Alan F. List, Amit Verma
Journal: Blood
Blood (2023) 142 (Supplement 1): 1417.
https://doi.org/10.1182/blood-2023-182289
Published: 2023
Journal Articles

Hematopoietic Stem Cell Numbers Are Regulated at Both Systemic and Local Levels

Shoichiro Takeishi, Tony Marchand, Wade R. Koba, Daniel K. Borger, Chunliang Xu, Chandan Guha, Aviv Bergman, Paul S. Frenette, Kira Gritsman, Ulrich Steidl
Journal: Blood
Blood (2023) 142 (Supplement 1): 511.
https://doi.org/10.1182/blood-2023-174407
Published: 2023
Journal Articles

Transcription Factor Redistributors Pharmacologically Actuate Non-Canonical Gene Networks to Drive AML Differentiation

Samuel Taylor, Jacob Stauber, Oliver Bohorquez, Emily Schwenger, Sriram Sundaravel, Abdelbasset Farahat, Boris Bartholdy, David Boykin, Gregory Poon, Ulrich Steidl
Journal: Blood
Blood (2023) 142 (Supplement 1): 119.
https://doi.org/10.1182/blood-2023-186698
Published: 2023
Journal Articles

Resistance to CD19 Immunotherapy in B-Cell ALL Is Associated with Loss of CD19 and CD22 and an Enhanced Vulnerability to B Cell Receptor Signaling Inhibition

Sarah Aminov, Orsi Giricz, R. Alejandro Sica, Veronika Polishchuk, Bonnie Yates, Hao-Wei Wang, Yanhua Wang, Srabani Sahu, Shanisha Gordon, Carolina Schinke, Kith Pradhan, Srinivas Aluri, Murali Janakiram, Stefan K. Barta, Beamon Agarwal, Mendel Goldfinger, Aditi Shastri, William Matsui, Ulrich Steidl, Joshua Brody, Nirali N. Shah, Samir Parekh, Amit Verma
Journal: Blood
Blood (2022) 140 (Supplement 1): 3480–3482.
https://doi.org/10.1182/blood-2022-169102
Published: 2022
Journal Articles

Outcomes Analysis of T-Cell Acute Lymphoblastic Leukemia/Lymphoblastic Lymphoma (T-ALL/T-LBL) in a Minority Rich Cohort

Karun Neupane, Abdul-Hamid Bazarbachi, Daniel K. Reef, Kith Pradhan, Hiba Narvel, Alyssa De Castro, Felisha Joseph, Kailyn Gillick, Fariha Khatun, Amanda Lombardo, Yang Shi, Yanhua Wang, Kira Gritsman, Ulrich Steidl, Mendel Goldfinger, Noah Kornblum, Aditi Shastri, Ioannis Mantzaris, Lizamarie Bachier Rodriguez, Nishi Shah, Dennis Cooper, Ira Braunschweig, Amit Verma, Bin Hilda Ye, Marina Konopleva, R. Alejandro Sica
Journal: Blood
Blood (2022) 140 (Supplement 1): 11595–11597.
https://doi.org/10.1182/blood-2022-159826
Published: 2022
Journal Articles

Allogeneic but Not Autologous Stem Cell Transplantation Improves Outcome in HTLV-1-Associated North American Adult T-Cell Leukemia/Lymphoma

Abdul-Hamid Bazarbachi, Daniel K. Reef, Hiba Narvel, Riya Patel, Rama Al Hamed, Astha Thakkar, Shafia Rahman, Urvi A Shah, Diego Adrianzen Herrera, Ryann Quinn, Sumaira Zareef, Emma Rabinovich, Alyssa De Castro, Felisha Joseph, Kailyn Gillick, Jennat Mustafa, Fariha Khatun, Amanda Lombardo, Latoya Townsend Nugent, Michelly Abreu, Nicole Chambers, Richard Elkind, Yang Shi, Yanhua Wang, Olga Derman, Kira Gritsman, Ulrich Steidl, Mendel Goldfinger, Noah Kornblum, Aditi Shastri, Ioannis Mantzaris, Lizamarie Bachier Rodriguez, Nishi Shah, Dennis Cooper, Ira Braunschweig, Amit Verma, B. Hilda Ye, Murali Janakiram, R. Alejandro Sica
Journal: Blood
Blood (2022) 140 (Supplement 1): 662–664.
https://doi.org/10.1182/blood-2022-170332
Published: 2022
Journal Articles

Posttranscriptional Arid3a deregulation in AMKL

Justin C. Wheat, Ulrich Steidl
Journal: Blood
Blood (2022) 139 (5): 637–638.
https://doi.org/10.1182/blood.2021014081
Published: 2022
Journal Articles

Transcriptional circuit dynamics in HSPCs

Goichi Tatsumi, Ulrich Steidl
Journal: Blood
Blood (2021) 138 (16): 1382–1384.
https://doi.org/10.1182/blood.2021012452
Published: 2021
Journal Articles

Gene expression at a single-molecule level: implications for myelodysplastic syndromes and acute myeloid leukemia

Justin C. Wheat, Ulrich Steidl
Journal: Blood
Blood (2021) 138 (8): 625–636.
https://doi.org/10.1182/blood.2019004261
Published: 2021
Journal Articles

Preleukemic and leukemic evolution at the stem cell level

Jacob Stauber, John M. Greally, Ulrich Steidl
Journal: Blood
Blood (2021) 137 (8): 1013–1018.
https://doi.org/10.1182/blood.2019004397
Published: 2021