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Tushar Damodar Bhagat
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Journal Articles

TGF-β1-SMAD2 Axis Regulates Hematopoiesis and β-Globin Gene Expression Via Super-Enhancer Associated Chromatin Reorganization

Srinivas Aluri, Kimo Bachiashvili, Anjali Budhathoki, Jong J Jeong, Shanisha Gordon Mitchell, Milagros Carbajal, Samarpana Chakraborty, Sanjay Pandey, Mahinder Paul Wadhwa, Srabani Sahu, Jung-In Yang, Gaurav S Choudhary, Tushar Damodar Bhagat, Nandini Ramachandra, Rongbao Zhao, Bianca Rivera, Ritesh Aggarwal, Kith Pradhan, Shahina Maqbool, Seong jin Kim, Sunjin Hwang, Ulrich Steidl, Aditi Shastri, Marc Raaijmakers, Andrea Pellagatti, Jacqueline Boultwood, Amittha Wickrema, Amit Verma
Journal: Blood
Blood (2024) 144 (Supplement 1): 878.
https://doi.org/10.1182/blood-2024-201101
Published: 2024
Journal Articles

Reduced Expression of DOCK4 Leads to Increased Protein Phosphorylation and Migration of Hematopoietic Stem/Progenitor Cells

Sriram Sundaravel, MS, Wen Liang-Kuo, PhD, Hui Liu, MS, Jong Jeong, PhD, Gaurav Choudhary, PhD, Tushar Damodar Bhagat, PhD, Shanisha Gordon, Amit Verma, MD, Amittha Wickrema, PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2563.
https://doi.org/10.1182/blood-2018-99-114320
Published: 2018
Journal Articles

Splicesome Mutant MDS and AML Cells Activate Innate Immune Signaling By Regulating the Expression of Therapeutically Targetable IRAK4 Isoforms

Molly A Smith, Gaurav Choudhary, PhD, Andrea Pellagatti, PhD, Kwangmin Choi, PhD, Tushar Damodar Bhagat, PhD, Nathan Salomonis, PhD, Matthew J. Walter, MD, Kakajan Komurov, Maria Elena S Sampson, Shanisha Gordon, Dagny Von Ahrens, Kith Pradhan, PhD, Ulrich G. Steidl, MDPhD, Robert Booher, PhD, Jacqueline Boultwood, PhD, Amit Verma, MD, Daniel Starczynowski, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 785.
https://doi.org/10.1182/blood.V130.Suppl_1.785.785
Published: 2017
Journal Articles

North American Adult T Cell Leukemia Lymphoma (ATLL) Is Characterized By Distinct, Therapeutically Targetable Mutations in Epigenetic Modifiers

Urvi A Shah, MD, Yanhua Wang, MD PhD, Orsolya Giricz, PhD, Shanisha Gordon, Tushar Damodar Bhagat, PhD, Yun Mai, PhD, Yongqiang Wei, MD, Nadege Gitego, Gaurav Choudhary, PhD, Kith Pradhan, PhD, Matthias Bartenstein, MD, Ronald Rice, DHSC, MD PhD, Swati Goel, MD, Ioannis Mantzaris, MD, Aditi Shastri, MD, Olga Derman, Adam F. Binder, MD, Kira Gritsman, MD PhD, Noah Kornblum, MD, Ira Braunschweig, MD, Amit Verma, MD, B. Hilda Ye, PhD, Murali Janakiram, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1455.
https://doi.org/10.1182/blood.V130.Suppl_1.1455.1455
Published: 2017
Journal Articles

Gls Inhibitor CB-839 Modulates Cellular Metabolism in AML and Potently Suppresses AML Cell Growth When Combined with 5-Azacitidine

Tianyu Cai, PhD, Philip L Lorenzi, PhD, Dinesh Rakheja, MD, Michael A Pontikos, Alessia Lodi, Lina Han, MD PhD, Qi Zhang, MD PhD, Helen Ma, MS, Mohamed Rahmani, PhD, Tushar Damodar Bhagat, PhD, Thomas D Horvath, PhD, Courtney D. DiNardo, MD MSCE, Steven Grant, MD, Stefano Tiziani, PhD, Amit Verma, MD, Marina Konopleva, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4064.
https://doi.org/10.1182/blood.V128.22.4064.4064
Published: 2016
Journal Articles

Targeting MDS and AML Stem Cells with AZD-9150 Mediated Inhibition of STAT3

Aditi Shastri, MD, Margarida Teixeira, PhD, Sanchari Bhattacharyya, PhD, Nandini Ramachandra, Msc, Robert Lopez, MD, Goutham Ravipati, Jonathan Feld, MD, Yosman Dhar, Tushar Damodar Bhagat, PhD, Gaurav Choudhary, PhD, Orsolya Giricz, PhD, Matthias Bartenstein, Ashwin Sridharan, MD, Shanisha Gordon-Mitchell, George Nawanko, Kith Pradhan, PhD, Amal Ahmed, Keshav Raghavendran, Rubashruti Kanna, Hina Khan, MD, Ioannis Mantzaris, MD, Andrea Pellagatti, PhD, Jacqueline Boultwood, PhD, Youngsoo Kim, PhD, Robert McLeod, Richard Woessner, PhD, Ulrich Steidl, MDPhD, Britta Will, PhD, Amit Verma, MD
Journal: Blood
Blood (2016) 128 (22): 4314.
https://doi.org/10.1182/blood.V128.22.4314.4314
Published: 2016