Skip Nav Destination

Issue Archive

Select Decade

Select Year

Issue

Volume 109, Issue 4

February 15 2007

In this Issue

INSIDE BLOOD
PLENARY PAPERS
PERSPECTIVE
REVIEW IN TRANSLATIONAL HEMATOLOGY
CHEMOKINES, CYTOKINES, AND INTERLEUKINS
CLINICAL TRIALS AND OBSERVATIONS
GENE THERAPY
HEMATOPOIESIS
HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY
IMMUNOBIOLOGY
NEOPLASIA
RED CELLS
STEM CELLS IN HEMATOLOGY
TRANSFUSION MEDICINE
TRANSPLANTATION
CORRESPONDENCE

INSIDE BLOOD

HEMOSTASIS

Novel function of RANKL: eNOS activator

Dai Fukumura,Rakesh K. Jain

View Articletitled, Novel function of RANKL: eNOS activator

HEMATOPOIESIS

On the origins of megakaryocytes

John D. Crispino

View Articletitled, On the origins of megakaryocytes

HEMOSTASIS

Happy to have the megakaryocyte blues

Andrew D. Leavitt

View Articletitled, Happy to have the megakaryocyte blues

CHEMOKINES

“Doing the locomotion” with the multistep paradigm

Richard M. Ransohoff,Shumei Man,Eroboghene E. Ubogu

View Articletitled, “Doing the locomotion” with the multistep paradigm

HEMOSTASIS

Endothelial cells in line

Lena Claesson-Welsh

View Articletitled, Endothelial cells in line

HEMOSTASIS

Scientific detectives solve ashen mutant problem

Timothy A. Lyerla

View Articletitled, Scientific detectives solve ashen mutant problem

PLENARY PAPERS

Orientation of endothelial cell division is regulated by VEGF signaling during blood vessel formation

Gefei Zeng,Sarah M. Taylor,Janet R. McColm,Nicholas C. Kappas,Joseph B. Kearney,Lucy H. Williams,Mary E. Hartnett,Victoria L. Bautch

View Articletitled, Orientation of endothelial cell division is regulated by VEGF signaling during blood vessel formation

Supplemental data

PERSPECTIVE

Bloodlines: the importance of mentoring for the future of hematology

Kenneth Kaushansky,Sanford J. Shattil

View Articletitled, Bloodlines: the importance of mentoring for the future of hematology

REVIEW IN TRANSLATIONAL HEMATOLOGY

Beyond HLA: the significance of genomic variation for allogeneic hematopoietic stem cell transplantation

Ann Mullally,Jerome Ritz

View Articletitled, Beyond HLA: the significance of genomic variation for allogeneic hematopoietic stem cell transplantation

CHEMOKINES, CYTOKINES, AND INTERLEUKINS

FGF2 posttranscriptionally down-regulates expression of SDF1 in bone marrow stromal cells through FGFR1 IIIc

Takayuki Nakayama,Noriko Mutsuga,Giovanna Tosato

View Articletitled, FGF2 posttranscriptionally down-regulates expression of SDF1 in bone marrow stromal cells through FGFR1 IIIc

Histone deacetylase inhibitors suppress IFNα-induced up-regulation of promyelocytic leukemia protein

Jana Vlasáková,Zora Nováková,Lenka Rossmeislová,Michal Kahle,Pavel Hozák,Zdenĕk Hodný

View Articletitled, Histone deacetylase inhibitors suppress IFNα-induced up-regulation of promyelocytic leukemia protein

Shear flow–dependent integration of apical and subendothelial chemokines in T-cell transmigration: implications for locomotion and the multistep paradigm

Taylor H. Schreiber,Vera Shinder,Derek W. Cain,Ronen Alon,Robert Sackstein

View Articletitled, Shear flow–dependent integration of apical and subendothelial chemokines in T-cell transmigration: implications for locomotion and the multistep paradigm

CLINICAL TRIALS AND OBSERVATIONS

A phase 2 study of the farnesyltransferase inhibitor tipifarnib in poor-risk and elderly patients with previously untreated acute myelogenous leukemia
Clinical Trials & Observations

Jeffrey E. Lancet,Ivana Gojo,Jason Gotlib,Eric J. Feldman,Jacqueline Greer,Jane L. Liesveld,Laura M. Bruzek,Lawrence Morris,Youn Park,Alex A. Adjei,Scott H. Kaufmann,Elizabeth Garrett-Mayer,Peter L. Greenberg,John J. Wright,Judith E. Karp

View Articletitled, A phase 2 study of the farnesyltransferase inhibitor tipifarnib in poor-risk and elderly patients with previously untreated acute myelogenous leukemia

Prospective feasibility analysis of reduced-intensity conditioning (RIC) regimens for hematopoietic stem cell transplantation (HSCT) in elderly patients with acute myeloid leukemia (AML) and high-risk myelodysplastic syndrome (MDS)
Clinical Trials & Observations

Elihu Estey,Marcos de Lima,Raoul Tibes,Sherry Pierce,Hagop Kantarjian,Richard Champlin,Sergio Giralt

View Articletitled, Prospective feasibility analysis of reduced-intensity conditioning (RIC) regimens for hematopoietic stem cell transplantation (HSCT) in elderly patients with acute myeloid leukemia (AML) and high-risk myelodysplastic syndrome (MDS)

Therapy with high-dose dexamethasone (HD-DXM) in previously untreated patients affected by idiopathic thrombocytopenic purpura: a GIMEMA experience
Clinical Trials & Observations

Maria Gabriella Mazzucconi,Paola Fazi,Sayla Bernasconi,Giulio De Rossi,Giuseppe Leone,Luigi Gugliotta,Nicola Vianelli,Giuseppe Avvisati,Francesco Rodeghiero,Angela Amendola,Carlo Baronci,Cecilia Carbone,Stefano Quattrin,Giuseppe Fioritoni,Giulio D'Alfonso,Franco Mandelli,for the Gruppo Italiano Malattie EMatologiche dell'Adulto (GIMEMA) Thrombocytopenia Working Party

View Articletitled, Therapy with high-dose dexamethasone (HD-DXM) in previously untreated patients affected by idiopathic thrombocytopenic purpura: a GIMEMA experience

Imatinib combined with induction or consolidation chemotherapy in patients with de novo Philadelphia chromosome–positive acute lymphoblastic leukemia: results of the GRAAPH-2003 study
Clinical Trials & Observations

Adrienne de Labarthe,Philippe Rousselot,Françoise Huguet-Rigal,Eric Delabesse,Francis Witz,Sébastien Maury,Delphine Réa,Jean-Michel Cayuela,Marie-Christine Vekemans,Oumedaly Reman,Agnès Buzyn,Arnaud Pigneux,Martine Escoffre,Yves Chalandon,Elizabeth MacIntyre,Véronique Lhéritier,Jean-Paul Vernant,Xavier Thomas,Norbert Ifrah,Hervé Dombret,for the Group for Research on Adult Acute Lymphoblastic Leukemia (GRAALL)

View Articletitled, Imatinib combined with induction or consolidation chemotherapy in patients with de novo Philadelphia chromosome–positive acute lymphoblastic leukemia: results of the GRAAPH-2003 study

Supplemental data

GENE THERAPY

Safe and efficient transduction of the liver after peripheral vein infusion of self-complementary AAV vector results in stable therapeutic expression of human FIX in nonhuman primates

Amit C. Nathwani,John T. Gray,Jenny McIntosh,Catherine Y. C. Ng,Junfang Zhou,Yunyu Spence,Melanie Cochrane,Elaine Gray,Edward G. D. Tuddenham,Andrew M. Davidoff

View Articletitled, Safe and efficient transduction of the liver after peripheral vein infusion of self-complementary AAV vector results in stable therapeutic expression of human FIX in nonhuman primates

HEMATOPOIESIS

Toll-like receptors and their ligands control mesenchymal stem cell functions

Meirav Pevsner-Fischer,Vered Morad,Michal Cohen-Sfady,Liat Rousso-Noori,Alexandra Zanin-Zhorov,Shmuel Cohen,Irun R. Cohen,Dov Zipori

View Articletitled, Toll-like receptors and their ligands control mesenchymal stem cell functions

The megakaryocyte lineage originates from hemangioblast precursors and is an integral component both of primitive and of definitive hematopoiesis

Joanna Tober,Anne Koniski,Kathleen E. McGrath,Radhika Vemishetti,Rachael Emerson,Karen K. L. de Mesy-Bentley,Richard Waugh,James Palis

View Articletitled, The megakaryocyte lineage originates from hemangioblast precursors and is an integral component both of primitive and of definitive hematopoiesis

Supplemental data

Caspase-8 prevents sustained activation of NF-κB in monocytes undergoing macrophagic differentiation

Cédric Rébé,Séverine Cathelin,Sophie Launay,Rodolphe Filomenko,Laurent Prévotat,Coralie L'Ollivier,Emmanuel Gyan,Olivier Micheau,Steven Grant,Anne Dubart-Kupperschmitt,Michaëla Fontenay,Eric Solary

View Articletitled, Caspase-8 prevents sustained activation of NF-κB in monocytes undergoing macrophagic differentiation

Supplemental data

Expression analysis of primary mouse megakaryocyte differentiation and its application in identifying stage-specific molecular markers and a novel transcriptional target of NF-E2

Zhao Chen,Michael Hu,Ramesh A. Shivdasani

View Articletitled, Expression analysis of primary mouse megakaryocyte differentiation and its application in identifying stage-specific molecular markers and a novel transcriptional target of NF-E2

Supplemental data

The hypomorphic Gata1^low mutation alters the proliferation/differentiation potential of the common megakaryocytic-erythroid progenitor

Barbara Ghinassi,Massimo Sanchez,Fabrizio Martelli,Giovanni Amabile,Alessandro Maria Vannucchi,Giovanni Migliaccio,Stuart H. Orkin,Anna Rita Migliaccio

View Articletitled, The hypomorphic Gata1low mutation alters the proliferation/differentiation potential of the common megakaryocytic-erythroid progenitor

Supplemental data

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

The histone methyltransferase MLL is an upstream regulator of endothelial-cell sprout formation

Florian Diehl,Lothar Rössig,Andreas M. Zeiher,Stefanie Dimmeler,Carmen Urbich

View Articletitled, The histone methyltransferase MLL is an upstream regulator of endothelial-cell sprout formation

Dissecting the role of endothelial SURVIVIN ΔEx3 in angiogenesis

Hugo Caldas,Jason R. Fangusaro,Daniel R. Boué,Michael P. Holloway,Rachel A. Altura

View Articletitled, Dissecting the role of endothelial SURVIVIN ΔEx3 in angiogenesis

Supplemental data

Correlation between antiphospholipid antibodies that recognize domain I of β2-glycoprotein I and a reduction in the anticoagulant activity of annexin A5

Bas de Laat,Xiao-Xuan Wu,Menno van Lummel,Ronald H. W. M. Derksen,Philip G. de Groot,Jacob H. Rand

View Articletitled, Correlation between antiphospholipid antibodies that recognize domain I of β2-glycoprotein I and a reduction in the anticoagulant activity of annexin A5

Receptor activator of nuclear factor (NF)–κB ligand (RANKL) increases vascular permeability: impaired permeability and angiogenesis in eNOS-deficient mice

Jeong-Ki Min,Young-Lai Cho,Jae-Hoon Choi,Yonghak Kim,Jeong Hun Kim,Young Suk Yu,Jaerang Rho,Naoki Mochizuki,Young-Myeong Kim,Goo Taeg Oh,Young-Guen Kwon

View Articletitled, Receptor activator of nuclear factor (NF)–κB ligand (RANKL) increases vascular permeability: impaired permeability and angiogenesis in eNOS-deficient mice

Supplemental data

Pf4-Cre transgenic mice allow the generation of lineage-restricted gene knockouts for studying megakaryocyte and platelet function in vivo

Ralph Tiedt,Tibor Schomber,Hui Hao-Shen,Radek C. Skoda

View Articletitled, Pf4-Cre transgenic mice allow the generation of lineage-restricted gene knockouts for studying megakaryocyte and platelet function in vivo

Supplemental data

The role of TLR2 in the inflammatory activation of mouse fibroblasts by human antiphospholipid antibodies

Nathalie Satta,Sylvie Dunoyer-Geindre,Guido Reber,Richard J. Fish,Francoise Boehlen,Egbert K. O. Kruithof,Philippe de Moerloose

View Articletitled, The role of TLR2 in the inflammatory activation of mouse fibroblasts by human antiphospholipid antibodies

Supplemental data

Caveolin-1 regulates expression of junction-associated proteins in brain microvascular endothelial cells

Li Song,Shujun Ge,Joel S. Pachter

View Articletitled, Caveolin-1 regulates expression of junction-associated proteins in brain microvascular endothelial cells

Deletion of tetraspanin Cd151 results in decreased pathologic angiogenesis in vivo and in vitro

Yoshito Takeda,Alexander R. Kazarov,Catherine E. Butterfield,Benjamin D. Hopkins,Laura E. Benjamin,Arja Kaipainen,Martin E. Hemler

View Articletitled, Deletion of tetraspanin Cd151 results in decreased pathologic angiogenesis in vivo and in vitro

Supplemental data

The Slc35d3 gene, encoding an orphan nucleotide sugar transporter, regulates platelet-dense granules

Sreenivasulu Chintala,Jian Tan,Rashi Gautam,Michael E. Rusiniak,Xiaoli Guo,Wei Li,William A. Gahl,Marjan Huizing,Richard A. Spritz,Saunie Hutton,Edward K. Novak,Richard T. Swank

View Articletitled, The Slc35d3 gene, encoding an orphan nucleotide sugar transporter, regulates platelet-dense granules

Antiadhesive effect of fibrinogen: a safeguard for thrombus stability

Valeryi K. Lishko,Timothy Burke,Tatiana Ugarova

View Articletitled, Antiadhesive effect of fibrinogen: a safeguard for thrombus stability

IMMUNOBIOLOGY

Kaposi sarcoma herpesvirus–encoded vFLIP and vIRF1 regulate antigen presentation in lymphatic endothelial cells

Dimitrios Lagos,Matthew W. B. Trotter,Richard J. Vart,Hsei-Wei Wang,Nick C. Matthews,Amy Hansen,Ornella Flore,Frances Gotch,Chris Boshoff

View Articletitled, Kaposi sarcoma herpesvirus–encoded vFLIP and vIRF1 regulate antigen presentation in lymphatic endothelial cells

Supplemental data

Progressive immunoglobulin gene mutations in chronic lymphocytic leukemia: evidence for antigen-driven intraclonal diversification

Alicia D. Volkheimer,J. Brice Weinberg,Bethany E. Beasley,John F. Whitesides,Jon P. Gockerman,Joseph O. Moore,Garnett Kelsoe,Barbara K. Goodman,Marc C. Levesque

View Articletitled, Progressive immunoglobulin gene mutations in chronic lymphocytic leukemia: evidence for antigen-driven intraclonal diversification

Supplemental data

l-arginine availability regulates T-lymphocyte cell-cycle progression

Paulo C. Rodriguez,David G. Quiceno,Augusto C. Ochoa

View Articletitled, l-arginine availability regulates T-lymphocyte cell-cycle progression

Supplemental data

Contribution of Toll-like receptors to the innate immune response to Gram-negative and Gram-positive bacteria

Greg Elson,Irène Dunn-Siegrist,Bruno Daubeuf,Jérome Pugin

View Articletitled, Contribution of Toll-like receptors to the innate immune response to Gram-negative and Gram-positive bacteria

Supplemental data

GSK-3 mediates differentiation and activation of proinflammatory dendritic cells

Elena Rodionova,Michael Conzelmann,Eugene Maraskovsky,Michael Hess,Michael Kirsch,Thomas Giese,Anthony D. Ho,Margot Zöller,Peter Dreger,Thomas Luft

View Articletitled, GSK-3 mediates differentiation and activation of proinflammatory dendritic cells

Supplemental data

Plasminogen activator inhibitor type 1 is protective during severe Gram-negative pneumonia

Rosemarijn Renckens,Joris J. T. H. Roelofs,Peter I. Bonta,Sandrine Florquin,Carlie J. M. de Vries,Marcel Levi,Peter Carmeliet,Cornelis van't Veer,Tom van der Poll

View Articletitled, Plasminogen activator inhibitor type 1 is protective during severe Gram-negative pneumonia

Function of CD4⁺CD3⁻ cells in relation to B- and T-zone stroma in spleen

Mi-Yeon Kim,Fiona M. McConnell,Fabrina M. C. Gaspal,Andrea White,Stephanie H. Glanville,Vasilios Bekiaris,Lucy S. K. Walker,Jorge Caamano,Eric Jenkinson,Graham Anderson,Peter J. L. Lane

View Articletitled, Function of CD4+CD3− cells in relation to B- and T-zone stroma in spleen

CpG DNA activation and plasma-cell differentiation of CD27⁻ naive human B cells

Jennifer Huggins,Tina Pellegrin,Raymond E. Felgar,Chungwen Wei,Miguel Brown,Bo Zheng,Eric C. B. Milner,Steven H. Bernstein,Ignacio Sanz,Martin S. Zand

View Articletitled, CpG DNA activation and plasma-cell differentiation of CD27− naive human B cells

The antiapoptotic protein Mcl-1 is essential for the survival of neutrophils but not macrophages

Ivan Dzhagalov,Ashley St. John,You-Wen He

View Articletitled, The antiapoptotic protein Mcl-1 is essential for the survival of neutrophils but not macrophages

The induction of Bim expression in human T-cell blasts is dependent on nonapoptotic Fas/CD95 signaling

Alberto Bosque,Juan Ignacio Aguiló,M. Angeles Alava,Estela Paz-Artal,Javier Naval,Luis M. Allende,Alberto Anel

View Articletitled, The induction of Bim expression in human T-cell blasts is dependent on nonapoptotic Fas/CD95 signaling

NEOPLASIA

The oncoprotein LMO2 is expressed in normal germinal-center B cells and in human B-cell lymphomas

Yasodha Natkunam,Shuchun Zhao,David Y. Mason,Jun Chen,Behnaz Taidi,Margaret Jones,Anne S. Hammer,Stephen Hamilton Dutoit,Izidore S. Lossos,Ronald Levy

View Articletitled, The oncoprotein LMO2 is expressed in normal germinal-center B cells and in human B-cell lymphomas

Prolonged exposure to FLT3 inhibitors leads to resistance via activation of parallel signaling pathways

Obdulio Piloto,Melissa Wright,Patrick Brown,Kyu-Tae Kim,Mark Levis,Donald Small

View Articletitled, Prolonged exposure to FLT3 inhibitors leads to resistance via activation of parallel signaling pathways

Supplemental data

Emodin and DHA potently increase arsenic trioxide interferon-α–induced cell death of HTLV-I–transformed cells by generation of reactive oxygen species and inhibition of Akt and AP-1

Megan Brown,Marcia Bellon,Christophe Nicot

View Articletitled, Emodin and DHA potently increase arsenic trioxide interferon-α–induced cell death of HTLV-I–transformed cells by generation of reactive oxygen species and inhibition of Akt and AP-1

Differential Noxa/Mcl-1 balance in peripheral versus lymph node chronic lymphocytic leukemia cells correlates with survival capacity

Laura A. Smit,Delfine Y.H. Hallaert,René Spijker,Bart de Goeij,Annelieke Jaspers,Arnon P. Kater,Marinus H.J. van Oers,Carel J.M. van Noesel,Eric Eldering

View Articletitled, Differential Noxa/Mcl-1 balance in peripheral versus lymph node chronic lymphocytic leukemia cells correlates with survival capacity

Targeting PKC in multiple myeloma: in vitro and in vivo effects of the novel, orally available small-molecule inhibitor enzastaurin (LY317615.HCl)

Klaus Podar,Marc S. Raab,Jing Zhang,Douglas McMillin,Iris Breitkreutz,Yu-Tzu Tai,Boris K. Lin,Nikhil Munshi,Teru Hideshima,Dharminder Chauhan,Kenneth C. Anderson

View Articletitled, Targeting PKC in multiple myeloma: in vitro and in vivo effects of the novel, orally available small-molecule inhibitor enzastaurin (LY317615.HCl)

Supplemental data

Constitutive activation of Stat5 promotes its cytoplasmic localization and association with PI3-kinase in myeloid leukemias

Noria Harir,Christian Pecquet,Marc Kerenyi,Karoline Sonneck,Boris Kovacic,Remy Nyga,Marie Brevet,Isabelle Dhennin,Valerie Gouilleux-Gruart,Hartmut Beug,Peter Valent,Kaiss Lassoued,Richard Moriggl,Fabrice Gouilleux

View Articletitled, Constitutive activation of Stat5 promotes its cytoplasmic localization and association with PI3-kinase in myeloid leukemias

Supplemental data

β common receptor inactivation attenuates myeloproliferative disease in Nf1 mutant mice

Andrew Kim,Kelly Morgan,Diane E. Hasz,Stephen M. Wiesner,Jennifer O. Lauchle,Jennifer L. Geurts,Miechaleen D. Diers,Doan T. Le,Scott C. Kogan,Luis F. Parada,Kevin Shannon,David A. Largaespada

View Articletitled, β common receptor inactivation attenuates myeloproliferative disease in Nf1 mutant mice

Supplemental data

Gene-expression signature of benign monoclonal gammopathy evident in multiple myeloma is linked to good prognosis

Fenghuang Zhan,Bart Barlogie,Varant Arzoumanian,Yongsheng Huang,David R. Williams,Klaus Hollmig,Mauricio Pineda-Roman,Guido Tricot,Frits van Rhee,Maurizio Zangari,Madhav Dhodapkar,John D. Shaughnessy, Jr

View Articletitled, Gene-expression signature of benign monoclonal gammopathy evident in multiple myeloma is linked to good prognosis

Supplemental data

Hypusination of eukaryotic initiation factor 5A (eIF5A): a novel therapeutic target in BCR-ABL–positive leukemias identified by a proteomics approach

Stefan Balabanov,Artur Gontarewicz,Patrick Ziegler,Ulrike Hartmann,Winfried Kammer,Mhairi Copland,Ute Brassat,Martin Priemer,Ilona Hauber,Thomas Wilhelm,Gerold Schwarz,Lothar Kanz,Carsten Bokemeyer,Joachim Hauber,Tessa L. Holyoake,Alfred Nordheim,Tim H. Brümmendorf

View Articletitled, Hypusination of eukaryotic initiation factor 5A (eIF5A): a novel therapeutic target in BCR-ABL–positive leukemias identified by a proteomics approach

PKC412 demonstrates JNK-dependent activity against human multiple myeloma cells

Janelle Sharkey,Tiffany Khong,Andrew Spencer

View Articletitled, PKC412 demonstrates JNK-dependent activity against human multiple myeloma cells

Gene-expression profiling and array-based CGH classify CD4⁺CD56⁺ hematodermic neoplasm and cutaneous myelomonocytic leukemia as distinct disease entities

Remco Dijkman,Remco van Doorn,Károly Szuhai,Rein Willemze,Maarten H. Vermeer,Cornelis P. Tensen

View Articletitled, Gene-expression profiling and array-based CGH classify CD4+CD56+ hematodermic neoplasm and cutaneous myelomonocytic leukemia as distinct disease entities

Supplemental data

RED CELLS

Urea stimulation of KCl cotransport induces abnormal volume reduction in sickle reticulocytes

Clinton H. Joiner,R. Kirk Rettig,Maorong Jiang,Mary Risinger,Robert S. Franco

View Articletitled, Urea stimulation of KCl cotransport induces abnormal volume reduction in sickle reticulocytes

Supplemental data

STEM CELLS IN HEMATOLOGY

The impact of altered p53 dosage on hematopoietic stem cell dynamics during aging

Melissa Dumble,Lynette Moore,Stuart M. Chambers,Hartmut Geiger,Gary Van Zant,Margaret A. Goodell,Lawrence A. Donehower

View Articletitled, The impact of altered p53 dosage on hematopoietic stem cell dynamics during aging

SSEA-4 identifies mesenchymal stem cells from bone marrow

Eun J. Gang,Darko Bosnakovski,Camila A. Figueiredo,Jan W. Visser,Rita C. R. Perlingeiro

View Articletitled, SSEA-4 identifies mesenchymal stem cells from bone marrow

Supplemental data

TRANSFUSION MEDICINE

Donor antibodies to HNA-3a implicated in TRALI reactions prime neutrophils and cause PMN-mediated damage to human pulmonary microvascular endothelial cells in a two-event in vitro model
Brief Report

Christopher C. Silliman,Brian R. Curtis,Patricia M. Kopko,Samina Y. Khan,Marguerite R. Kelher,Randy M. Schuller,Baindu Sannoh,Daniel R. Ambruso

View Articletitled, Donor antibodies to HNA-3a implicated in TRALI reactions prime neutrophils and cause PMN-mediated damage to human pulmonary microvascular endothelial cells in a two-event in vitro model

TRANSPLANTATION

Donor-derived thymic-dependent T cells cause chronic graft-versus-host disease

Yukimi Sakoda,Daigo Hashimoto,Shoji Asakura,Kengo Takeuchi,Mine Harada,Mitsune Tanimoto,Takanori Teshima

View Articletitled, Donor-derived thymic-dependent T cells cause chronic graft-versus-host disease

Diabetes, hypertension, and cardiovascular events in survivors of hematopoietic cell transplantation: a report from the bone marrow transplantation survivor study

K. Scott Baker,Kirsten K. Ness,Julia Steinberger,Andrea Carter,Liton Francisco,Linda J. Burns,Charles Sklar,Stephen Forman,Daniel Weisdorf,James G. Gurney,Smita Bhatia

View Articletitled, Diabetes, hypertension, and cardiovascular events in survivors of hematopoietic cell transplantation: a report from the bone marrow transplantation survivor study

B-cell extrinsic CR1/CR2 promotes natural antibody production and tolerance induction of anti-αGAL–producing B-1 cells

Ichiro Shimizu,Toshiyasu Kawahara,Fabienne Haspot,Philip D. Bardwell,Michael C. Carroll,Megan Sykes

View Articletitled, B-cell extrinsic CR1/CR2 promotes natural antibody production and tolerance induction of anti-αGAL–producing B-1 cells

The effects of imatinib mesylate treatment before allogeneic transplantation for chronic myeloid leukemia
Clinical Trials & Observations

Vivian G. Oehler,Ted Gooley,David S. Snyder,Laura Johnston,Allen Lin,Carrie C. Cummings,Su Chu,Ravi Bhatia,Stephen J. Forman,Robert S. Negrin,Frederick R. Appelbaum,Jerald P. Radich

View Articletitled, The effects of imatinib mesylate treatment before allogeneic transplantation for chronic myeloid leukemia

CORRESPONDENCE

Imatinib concentrations in human milk

Carlo B. Gambacorti-Passerini,Lucia Tornaghi,Elena Marangon,Anna Franceschino,Enrico M. Pogliani,Maurizio D'Incalci,Massimo Zucchetti

View Articletitled, Imatinib concentrations in human milk

Cover Image

Cover Image
Front Matter
Table of Contents
Advertising
Editorial Board

All Issues

Advertisement intended for health care professionals

Email alerts

First Edition Alert

Latest Issue Alert

Latest
Most Read
Most Cited

Licking the wound with procoagulant vesicles

Approaching Hypercalcemia in Monoclonal Gammopathy of Undetermined Significance: Insights from the iStopMM study

CAR T-cells in autoimmunity: game changer or stepping stone?

Long-Term Efficacy and Safety of Danicopan as Add-On Therapy to Ravulizumab or Eculizumab in PNH With Significant EVH

How I treat quantitative fibrinogen disorders

Advertisement intended for health care professionals

Issue Archive

Table of Contents

INSIDE BLOOD

PLENARY PAPERS

PERSPECTIVE

REVIEW IN TRANSLATIONAL HEMATOLOGY

CHEMOKINES, CYTOKINES, AND INTERLEUKINS

CLINICAL TRIALS AND OBSERVATIONS

A phase 2 study of the farnesyltransferase inhibitor tipifarnib in poor-risk and elderly patients with previously untreated acute myelogenous leukemia Clinical Trials & Observations

Prospective feasibility analysis of reduced-intensity conditioning (RIC) regimens for hematopoietic stem cell transplantation (HSCT) in elderly patients with acute myeloid leukemia (AML) and high-risk myelodysplastic syndrome (MDS) Clinical Trials & Observations

Therapy with high-dose dexamethasone (HD-DXM) in previously untreated patients affected by idiopathic thrombocytopenic purpura: a GIMEMA experience Clinical Trials & Observations

Imatinib combined with induction or consolidation chemotherapy in patients with de novo Philadelphia chromosome–positive acute lymphoblastic leukemia: results of the GRAAPH-2003 study Clinical Trials & Observations

GENE THERAPY

HEMATOPOIESIS

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

IMMUNOBIOLOGY

NEOPLASIA

RED CELLS

STEM CELLS IN HEMATOLOGY

TRANSFUSION MEDICINE

Donor antibodies to HNA-3a implicated in TRALI reactions prime neutrophils and cause PMN-mediated damage to human pulmonary microvascular endothelial cells in a two-event in vitro model Brief Report

TRANSPLANTATION

The effects of imatinib mesylate treatment before allogeneic transplantation for chronic myeloid leukemia Clinical Trials & Observations

CORRESPONDENCE

Cover Image

Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only

A phase 2 study of the farnesyltransferase inhibitor tipifarnib in poor-risk and elderly patients with previously untreated acute myelogenous leukemia
Clinical Trials & Observations

Prospective feasibility analysis of reduced-intensity conditioning (RIC) regimens for hematopoietic stem cell transplantation (HSCT) in elderly patients with acute myeloid leukemia (AML) and high-risk myelodysplastic syndrome (MDS)
Clinical Trials & Observations

Therapy with high-dose dexamethasone (HD-DXM) in previously untreated patients affected by idiopathic thrombocytopenic purpura: a GIMEMA experience
Clinical Trials & Observations

Imatinib combined with induction or consolidation chemotherapy in patients with de novo Philadelphia chromosome–positive acute lymphoblastic leukemia: results of the GRAAPH-2003 study
Clinical Trials & Observations

Donor antibodies to HNA-3a implicated in TRALI reactions prime neutrophils and cause PMN-mediated damage to human pulmonary microvascular endothelial cells in a two-event in vitro model
Brief Report

The effects of imatinib mesylate treatment before allogeneic transplantation for chronic myeloid leukemia
Clinical Trials & Observations