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Journal Articles

Systemic Inflammation Induces Release of Cell-Free DNA from Hematopoietic and Parenchymal Cells in Mice and Human

Anna Kroeze, MD, Anne Jan van der Meer, MD, Arie J Hoogendijk, PhD, Aicha Ait Soussan, C. Ellen van der Schoot, MD PhD, Walter A Wuillemin, MD PhD, Carlijn Voermans, PhD, Tom van der Poll, MD PhD, Sacha S Zeerleder, MD PhD

Blood (2018) 132 (Supplement 1): 1107.

https://doi.org/10.1182/blood-2018-99-114468

Published: 2018

Journal Articles

Platelet glycoprotein VI aids in local immunity during pneumonia-derived sepsis caused by gram-negative bacteria

Theodora A. M. Claushuis, Alex F. de Vos, Bernard Nieswandt, Louis Boon, Joris J. T. H. Roelofs, Onno J. de Boer, Cornelis van ’t Veer, Tom van der Poll

Blood (2018) 131 (8): 864–876.

https://doi.org/10.1182/blood-2017-06-788067

Published: 2018

Includes: Supplemental data

Journal Articles

Thrombocytopenia is associated with a dysregulated host response in critically ill sepsis patients

Theodora A. M. Claushuis, Lonneke A. van Vught, Brendon P. Scicluna, Maryse A. Wiewel, Peter M. C. Klein Klouwenberg, Arie J. Hoogendijk, David S. Y. Ong, Olaf L. Cremer, Janneke Horn, Marek Franitza, Mohammad R. Toliat, Peter Nürnberg, Aeilko H. Zwinderman, Marc J. Bonten, Marcus J. Schultz, Tom van der Poll

Blood (2016) 127 (24): 3062–3072.

https://doi.org/10.1182/blood-2015-11-680744

Published: 2016

Includes: Supplemental data

Journal Articles

Thrombocytopenia impairs host defense in gram-negative pneumonia–derived sepsis in mice

Sacha F. de Stoppelaar, Cornelis van ’t Veer, Theodora A. M. Claushuis, Bregje J. A. Albersen, Joris J. T. H. Roelofs, Tom van der Poll

Blood (2014) 124 (25): 3781–3790.

https://doi.org/10.1182/blood-2014-05-573915

Published: 2014

Includes: Supplemental data

Journal Articles

TAM receptors, Gas6, and protein S: roles in inflammation and hemostasis

Jonathan H. M. van der Meer, Tom van der Poll, Cornelis van ‘t Veer

Blood (2014) 123 (16): 2460–2469.

https://doi.org/10.1182/blood-2013-09-528752

Published: 2014

Journal Articles

The endothelial protein C receptor and malaria

Tom van der Poll

Blood (2013) 122 (5): 624–625.

https://doi.org/10.1182/blood-2013-06-508531

Published: 2013

Journal Articles

Asthma and coagulation

J. Daan de Boer, Christof J. Majoor, Cornelis van 't Veer, Elisabeth H. D. Bel, Tom van der Poll

Blood (2012) 119 (14): 3236–3244.

https://doi.org/10.1182/blood-2011-11-391532

Published: 2012

Journal Articles

β 2 -Glycoprotein I: a novel component of innate immunity

Çetin Ağar, Philip G. de Groot, Matthias Mörgelin, Stephanie D. D. C. Monk, Gwendolyn van Os, Johannes H. M. Levels, Bas de Laat, Rolf T. Urbanus, Heiko Herwald, Tom van der Poll, Joost C. M. Meijers

Blood (2011) 117 (25): 6939–6947.

https://doi.org/10.1182/blood-2010-12-325951

Published: 2011

Journal Articles

Thrombin and diabetic nephropathy

Tom van der Poll

Blood (2011) 117 (19): 5015–5016.

https://doi.org/10.1182/blood-2011-03-342733

Published: 2011

Journal Articles

Hyperglycemia enhances coagulation and reduces neutrophil degranulation, whereas hyperinsulinemia inhibits fibrinolysis during human endotoxemia

Michiel E. Stegenga, Saskia N. van der Crabben, Regje M. E. Blümer, Marcel Levi, Joost C. M. Meijers, Mireille J. Serlie, Michael W. T. Tanck, Hans P. Sauerwein, Tom van der Poll

Blood (2008) 112 (1): 82–89.

https://doi.org/10.1182/blood-2007-11-121723

Published: 2008

Journal Articles

Plasminogen activator inhibitor type 1 is protective during severe Gram-negative pneumonia

Rosemarijn Renckens, Joris J. T. H. Roelofs, Peter I. Bonta, Sandrine Florquin, Carlie J. M. de Vries, Marcel Levi, Peter Carmeliet, Cornelis van't Veer, Tom van der Poll

Blood (2006) 109 (4): 1593–1601.

https://doi.org/10.1182/blood-2006-05-025197

Published: 2006

Journal Articles

A Reduced Capacity To Generate Activated Protein C and the Role of PAI-1 Deficiency on Coagulation Activation and Fibrin Formation during Murine Influenza Pneumonia.

Tymen Keller, Matthijs van Wissen, Koen van der Sluijs, PhD, Eric van Gorp, PhD, Joost Meijers, PhD, Tom van der Poll, PhD, Harry Buller, PhD, Dees Brandjes, PhD, Marcel Levi, PhD, Victor Gerdes, PhD

Blood (2005) 106 (11): 2134.

https://doi.org/10.1182/blood.V106.11.2134.2134

Published: 2005

Journal Articles

A thrombomodulin mutation that impairs activated protein C generation results in uncontrolled lung inflammation during murine tuberculosis

Sebastiaan Weijer, Catharina W. Wieland, Sandrine Florquin, Tom van der Poll

Blood (2005) 106 (8): 2761–2768.

https://doi.org/10.1182/blood-2004-12-4623

Published: 2005

Journal Articles

Thrombomodulin mutant mice with a strongly reduced capacity to generate activated protein C have an unaltered pulmonary immune response to respiratory pathogens and lipopolysaccharide

Anita W. Rijneveld, Sebastiaan Weijer, Sandrine Florquin, Charles T. Esmon, Joost C. M. Meijers, Peter Speelman, Pieter H. Reitsma, Hugo Ten Cate, Tom van der Poll

Blood (2004) 103 (5): 1702–1709.

https://doi.org/10.1182/blood-2002-05-1380

Published: 2004

Journal Articles

Plasminogen activator inhibitor type–1 deficiency does not influence the outcome of murine pneumococcal pneumonia

Anita W. Rijneveld, Sandrine Florquin, Paul Bresser, Marcel Levi, Vivian de Waard, Roger Lijnen, Jaring S. Van der Zee, Peter Speelman, Peter Carmeliet, Tom van der Poll

Blood (2003) 102 (3): 934–939.

https://doi.org/10.1182/blood-2003-01-0227

Published: 2003

Journal Articles

Aggravation of endotoxin-induced disseminated intravascular coagulation and cytokine activation in heterozygous protein-C–deficient mice

Marcel Levi, Janine Dörffler-Melly, Pieter Reitsma, Harry Büller, Sandrine Florquin, Tom van der Poll, Peter Carmeliet

Blood (2003) 101 (12): 4823–4827.

https://doi.org/10.1182/blood-2002-10-3254

Published: 2003

Journal Articles

Inhibition of coagulation, fibrinolysis, and endothelial cell activation by a p38 mitogen-activated protein kinase inhibitor during human endotoxemia

Judith Branger, Bernt van den Blink, Sebastiaan Weijer, Abhya Gupta, Sander J.H. van Deventer, C. Erik Hack, Maikel P. Peppelenbosch, Tom van der Poll

Blood (2003) 101 (11): 4446–4448.

https://doi.org/10.1182/blood-2002-11-3338

Published: 2003

Journal Articles

Up-regulation of HIV coreceptors CXCR4 and CCR5 on CD4 + T cells during human endotoxemia and after stimulation with (myco)bacterial antigens: the role of cytokines

Nicole P. Juffermans, William A. Paxton, Pascale E. P. Dekkers, Annelies Verbon, Evert de Jonge, Peter Speelman, Sander J. H. van Deventer, Tom van der Poll

Blood (2000) 96 (8): 2649–2654.

https://doi.org/10.1182/blood.V96.8.2649

Published: 2000

Journal Articles

The in vivo kinetics of tissue factor messenger RNA expression during human endotoxemia: relationship with activation of coagulation

Rendrik F. Franco, Evert de Jonge, Pascale E. P. Dekkers, Janneke J. Timmerman, C. Arnold Spek, Sander J. H. van Deventer, Peter van Deursen, Liesbeth van Kerkhoff, Bob van Gemen, Hugo ten Cate, Tom van der Poll, Pieter H. Reitsma

Blood (2000) 96 (2): 554–559.

https://doi.org/10.1182/blood.V96.2.554

Published: 2000

Journal Articles

Tissue factor pathway inhibitor dose-dependently inhibits coagulation activation without influencing the fibrinolytic and cytokine response during human endotoxemia

Evert de Jonge, Pascale E. P. Dekkers, Abla A. Creasey, C. Erik Hack, Susan K. Paulson, Aziz Karim, Jozef Kesecioglu, Marcel Levi, Sander J. H. van Deventer, Tom van der Poll

Blood (2000) 95 (4): 1124–1129.

https://doi.org/10.1182/blood.V95.4.1124.002k20_1124_1129

Published: 2000

NARROW

Systemic Inflammation Induces Release of Cell-Free DNA from Hematopoietic and Parenchymal Cells in Mice and Human

Platelet glycoprotein VI aids in local immunity during pneumonia-derived sepsis caused by gram-negative bacteria

Thrombocytopenia is associated with a dysregulated host response in critically ill sepsis patients

Thrombocytopenia impairs host defense in gram-negative pneumonia–derived sepsis in mice

TAM receptors, Gas6, and protein S: roles in inflammation and hemostasis

The endothelial protein C receptor and malaria

Asthma and coagulation

β 2 -Glycoprotein I: a novel component of innate immunity

Thrombin and diabetic nephropathy

Hyperglycemia enhances coagulation and reduces neutrophil degranulation, whereas hyperinsulinemia inhibits fibrinolysis during human endotoxemia

Plasminogen activator inhibitor type 1 is protective during severe Gram-negative pneumonia

A Reduced Capacity To Generate Activated Protein C and the Role of PAI-1 Deficiency on Coagulation Activation and Fibrin Formation during Murine Influenza Pneumonia.

A thrombomodulin mutation that impairs activated protein C generation results in uncontrolled lung inflammation during murine tuberculosis

Thrombomodulin mutant mice with a strongly reduced capacity to generate activated protein C have an unaltered pulmonary immune response to respiratory pathogens and lipopolysaccharide

Plasminogen activator inhibitor type–1 deficiency does not influence the outcome of murine pneumococcal pneumonia

Aggravation of endotoxin-induced disseminated intravascular coagulation and cytokine activation in heterozygous protein-C–deficient mice

Inhibition of coagulation, fibrinolysis, and endothelial cell activation by a p38 mitogen-activated protein kinase inhibitor during human endotoxemia

Up-regulation of HIV coreceptors CXCR4 and CCR5 on CD4 + T cells during human endotoxemia and after stimulation with (myco)bacterial antigens: the role of cytokines

The in vivo kinetics of tissue factor messenger RNA expression during human endotoxemia: relationship with activation of coagulation

Tissue factor pathway inhibitor dose-dependently inhibits coagulation activation without influencing the fibrinolytic and cytokine response during human endotoxemia

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American Society of Hematology

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American Society of Hematology

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