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Journal Articles

Phase 1 Study of the Safety and Pharmacodynamics of a Single Dose of Vmx-C001 in Healthy Subjects with and without FXa Direct Oral Anticoagulants

Gerard Short, Michael Zoerer, Emma Hilton, Taina Gomes, Jan Ohrstrom, Bo Persson, Daniël Verhoef, Pieter H. Reitsma

Blood (2024) 144 (Supplement 1): 2624.

https://doi.org/10.1182/blood-2024-201421

Published: 2024

Journal Articles

Vmx-C001 Prevents Rivaroxaban-Induced Bleeding in a Liver Injury Model in Cynomolgus Monkeys

Daniël Verhoef, Viola J.F. Strijbis, Taina Gomes, Jan Ohrstrom, Gerard Short, Michael Zoerer, Pieter H. Reitsma

Blood (2024) 144 (Supplement 1): 1195.

https://doi.org/10.1182/blood-2024-205141

Published: 2024

Journal Articles

Human Prothrombin Variants with Modifications in the Active Site S4 Subpocket Demonstrate Resistance to Dabigatran

Viola J.F. Strijbis, Ka Lei Cheung, Tessa A. Rutten, Pieter H. Reitsma, Daniel Verhoef, Mettine H.A. Bos

Blood (2021) 138 (Supplement 1): 439.

https://doi.org/10.1182/blood-2021-150212

Published: 2021

Journal Articles

Whole-exome sequencing identifies rare variants in STAB2 associated with venous thromboembolic disease

Karl C. Desch, Ayse B. Ozel, Matt Halvorsen, Paula M. Jacobi, Krista Golden, Mary Underwood, Marine Germain, David-Alexandre Tregouet, Pieter H. Reitsma, Clive Kearon, Lauren Mokry, J. Brent Richards, Frances Williams, Jun Z. Li, David Goldstein, David Ginsburg

Blood (2020) 136 (5): 533–541.

https://doi.org/10.1182/blood.2019004161

Published: 2020

Includes: Supplemental data

Journal Articles

Mouse venous thrombosis upon silencing of anticoagulants depends on tissue factor and platelets, not FXII or neutrophils

Marco Heestermans, Salam Salloum-Asfar, Tom Streef, El Houari Laghmani, Daniela Salvatori, Brenda M. Luken, Sacha S. Zeerleder, Henri M. H. Spronk, Suzanne J. Korporaal, Daniel Kirchhofer, Gerry T. M. Wagenaar, Henri H. Versteeg, Pieter H. Reitsma, Thomas Renné, Bart J. M. van Vlijmen

Blood (2019) 133 (19): 2090–2099.

https://doi.org/10.1182/blood-2018-06-853762

Published: 2019

Includes: Supplemental data

Journal Articles

Phe174-Mutated Human Factor X As Bypassing Agent to the Direct FXa Inhibitors

Mark Schreuder, MD, Daniel Verhoef, MSc, Ka Lei Cheung, Koen Visscher, MSc, Daan Geerke, PhD, Pieter H. Reitsma, PhD, Mettine H.A. Bos, PhD

Blood (2017) 130 (Supplement 1): 363.

https://doi.org/10.1182/blood.V130.Suppl_1.363.363

Published: 2017

Journal Articles

Exome Sequencing Studies Identify Mutations in STAB2 As a Genetic Risk for Venous Thromboembolic Disease

Karl Desch, MD, Ayse Bilge Ozel, PhD, Matthew Halvorsen, PhD, Alison L. Michels, Laura L Swystun, BSc, PhD, Lauren Mokry, PhD, Brent Richards, Marine Germain, David A. Tregouet, PhD, Pieter H. Reitsma, PhD, Clive Kearon, MB, Jun Z Li, PhD, David B. Goldstein, PhD, David Lillicrap, MD FRCPC, David Ginsburg, MD

Blood (2017) 130 (Supplement 1): 457.

https://doi.org/10.1182/blood.V130.Suppl_1.457.457

Published: 2017

Journal Articles

Exome Sequencing in Venous Thromboembolic Disease Identifies Excess Mutation Burden in PROS1, PROC, SERPINC1 and STAB2

Karl C. Desch, MD, Ayse Bilge Ozel, PhD, Matt Halvorsen, PhD, Paula M. Jacobi, Marine Germain, PhD, David Alexandre Tregouet, PhD, Pieter H. Reitsma, David Goldstein, PhD, David Ginsburg, MD

Blood (2016) 128 (22): 3794.

https://doi.org/10.1182/blood.V128.22.3794.3794

Published: 2016

Journal Articles

Role of platelets, neutrophils, and factor XII in spontaneous venous thrombosis in mice

Marco Heestermans, Salam Salloum-Asfar, Daniela Salvatori, El Houari Laghmani, Brenda M. Luken, Sacha S. Zeerleder, Henri M. H. Spronk, Suzanne J. Korporaal, Gerry T. M. Wagenaar, Pieter H. Reitsma, Bart J. M. van Vlijmen

Blood (2016) 127 (21): 2630–2637.

https://doi.org/10.1182/blood-2015-10-672766

Published: 2016

Includes: Supplemental data

Journal Articles

Engineered Factor Xa Variants Retain Procoagulant Activity Independent of Direct Factor Xa-Inhibitors

Daniël Verhoef, Mark Schreuder, Ka Lei Cheung, Pieter H. Reitsma, Mettine H.A. Bos, PhD

Blood (2015) 126 (23): 126.

https://doi.org/10.1182/blood.V126.23.126.126

Published: 2015

Journal Articles

Protein S levels and the risk of venous thrombosis: results from the MEGA case-control study

Maria Carolina Pintao, Daniel D. Ribeiro, Irene D. Bezemer, Andrea A. Garcia, Marieke C. H. de Visser, Carine J. M. Doggen, Willem M. Lijfering, Pieter H. Reitsma, Frits R. Rosendaal

Blood (2013) 122 (18): 3210–3219.

https://doi.org/10.1182/blood-2013-04-499335

Published: 2013

Journal Articles

Acute and severe coagulopathy in adult mice following silencing of hepatic antithrombin and protein C production

Huma Safdar, Ka Lei Cheung, Daniela Salvatori, Henri H. Versteeg, El Houari Laghmani, Gerry T. M. Wagenaar, Pieter H. Reitsma, Bart J. M. van Vlijmen

Blood (2013) 121 (21): 4413–4416.

https://doi.org/10.1182/blood-2012-11-465674

Published: 2013

Includes: Supplemental data

Journal Articles

Analysis of the storage and secretion of von Willebrand factor in blood outgrowth endothelial cells derived from patients with von Willebrand disease

Jiong-Wei Wang, Eveline A. M. Bouwens, Maria Carolina Pintao, Jan Voorberg, Huma Safdar, Karine M. Valentijn, Hetty C. de Boer, Koen Mertens, Pieter H. Reitsma, Jeroen Eikenboom

Blood (2013) 121 (14): 2762–2772.

https://doi.org/10.1182/blood-2012-06-434373

Published: 2013

Includes: Supplemental data

Journal Articles

Biogenesis and Exocytosis of Weibel-Palade Bodies Is Affected by Naturally Occurring Von Willebrand Disease Variants within the A1-A3 Domains of VWF

Dafna J Groeneveld, Msc, Jiong-Wei Wang, Msc, Marjon J Mourik, Msc, Richard J Dirven, Bsc, Karine M Valentijn, PhD, Jan Voorberg, PhD, Pieter H. Reitsma, PhD, Jeroen C. J. Eikenboom, MD, PhD

Blood (2012) 120 (21): 1072.

https://doi.org/10.1182/blood.V120.21.1072.1072

Published: 2012

Journal Articles

Multiple SNP testing improves risk prediction of first venous thrombosis

Hugoline G. de Haan, Irene D. Bezemer, Carine J. M. Doggen, Saskia Le Cessie, Pieter H. Reitsma, Andre R. Arellano, Carmen H. Tong, James J. Devlin, Lance A. Bare, Frits R. Rosendaal, Carla Y. Vossen

Blood (2012) 120 (3): 656–663.

https://doi.org/10.1182/blood-2011-12-397752

Published: 2012

Includes: Supplemental data

Journal Articles

The relationship between tissue factor and cancer progression: insights from bench and bedside

Yascha W. van den Berg, Susanne Osanto, Pieter H. Reitsma, Henri H. Versteeg

Blood (2012) 119 (4): 924–932.

https://doi.org/10.1182/blood-2011-06-317685

Published: 2012

Journal Articles

Free and Total Protein S Antigen Levels on the Risk of Venous Thrombosis: Results From the MEGA Study

Daniel D. Ribeiro, MD, Maria Carolina T. Pintao, PhD, Willem M. Lijfering, PhD, Pieter H. Reitsma, PhD, Frits R. Rosendaal, PhD

Blood (2011) 118 (21): 538.

https://doi.org/10.1182/blood.V118.21.538.538

Published: 2011

Journal Articles

Complete abolishment of coagulant activity in monomeric disulfide-deficient tissue factor

Lisa G. van den Hengel, Begüm Kocatürk, Pieter H. Reitsma, Wolfram Ruf, Henri H. Versteeg

Blood (2011) 118 (12): 3446–3448.

https://doi.org/10.1182/blood-2011-06-364612

Published: 2011

Journal Articles

High Levels of Protein C Are Determinated by PROCR H3 in a Dutch Family.

Maria Carolina Pintao, MD, Sara Roshani, Marieke C.H. de Visser, MD, PhD, Cris Tieken, Michael W.T. Tanck, PhD, Harry Roger Buller, MD, PhD, Iris M Wichers, Joost C.M. Meijers, PhD, Saskia Middeldorp, MD, PhD, Pieter H. Reitsma, PhD

Blood (2009) 114 (22): 2139.

https://doi.org/10.1182/blood.V114.22.2139.2139

Published: 2009

Journal Articles

Genetic Risk Factors of Thrombosis.

Pieter H. Reitsma, PhD

Blood (2009) 114 (22): SCI-43.

https://doi.org/10.1182/blood.V114.22.SCI-43.SCI-43

Published: 2009

NARROW

Phase 1 Study of the Safety and Pharmacodynamics of a Single Dose of Vmx-C001 in Healthy Subjects with and without FXa Direct Oral Anticoagulants

Vmx-C001 Prevents Rivaroxaban-Induced Bleeding in a Liver Injury Model in Cynomolgus Monkeys

Human Prothrombin Variants with Modifications in the Active Site S4 Subpocket Demonstrate Resistance to Dabigatran

Whole-exome sequencing identifies rare variants in STAB2 associated with venous thromboembolic disease

Mouse venous thrombosis upon silencing of anticoagulants depends on tissue factor and platelets, not FXII or neutrophils

Phe174-Mutated Human Factor X As Bypassing Agent to the Direct FXa Inhibitors

Exome Sequencing Studies Identify Mutations in STAB2 As a Genetic Risk for Venous Thromboembolic Disease

Exome Sequencing in Venous Thromboembolic Disease Identifies Excess Mutation Burden in PROS1, PROC, SERPINC1 and STAB2

Role of platelets, neutrophils, and factor XII in spontaneous venous thrombosis in mice

Engineered Factor Xa Variants Retain Procoagulant Activity Independent of Direct Factor Xa-Inhibitors

Protein S levels and the risk of venous thrombosis: results from the MEGA case-control study

Acute and severe coagulopathy in adult mice following silencing of hepatic antithrombin and protein C production

Analysis of the storage and secretion of von Willebrand factor in blood outgrowth endothelial cells derived from patients with von Willebrand disease

Biogenesis and Exocytosis of Weibel-Palade Bodies Is Affected by Naturally Occurring Von Willebrand Disease Variants within the A1-A3 Domains of VWF

Multiple SNP testing improves risk prediction of first venous thrombosis

The relationship between tissue factor and cancer progression: insights from bench and bedside

Free and Total Protein S Antigen Levels on the Risk of Venous Thrombosis: Results From the MEGA Study

Complete abolishment of coagulant activity in monomeric disulfide-deficient tissue factor

High Levels of Protein C Are Determinated by PROCR H3 in a Dutch Family.

Genetic Risk Factors of Thrombosis.

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American Society of Hematology

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American Society of Hematology

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