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Journal Articles

Saliva of persons with hemophilia A triggers coagulation via extrinsic tenase complexes

Johannes Thaler, Carla Tripisciano, Daniel Kraemmer, Chi Hau, Nazanin Samadi, Wolfram Ruf, Ingrid Pabinger, Paul Knoebl, Rienk Nieuwland, Cihan Ay

Blood (2024) 144 (25): 2666–2677.

https://doi.org/10.1182/blood.2024025093

Published: 2024

Includes: Supplemental data

Journal Articles

Barrier disruption by coagulation FXIa

Philip Wenzel, Wolfram Ruf

Blood (2024) 144 (17): 1760–1762.

https://doi.org/10.1182/blood.2024026283

Published: 2024

Journal Articles

Targeting the tissue factor coagulation initiation complex prevents antiphospholipid antibody development

Nadine Müller-Calleja, Kristin Grunz, T. Son Nguyen, Jens Posma, Denise Pedrosa, Myriam Meineck, Anne Hollerbach, Johannes Braun, Sabine Muth, Hansjörg Schild, Kathrin Saar, Norbert Hübner, Sriram Krishnaswamy, Jennifer Royce, Luc Teyton, Niels Lemmermann, Julia Weinmann-Menke, Karl J. Lackner, Wolfram Ruf

Blood (2024) 143 (12): 1167–1180.

https://doi.org/10.1182/blood.2023022276

Published: 2024

Includes: Supplemental data

Journal Articles

Nucleic acid sensing promotes inflammatory monocyte migration through biased coagulation factor VIIa signaling

Hortensia Zelaya, Kristin Grunz, T. Son Nguyen, Anxhela Habibi, Claudius Witzler, Sabine Reyda, Irene Gonzalez-Menendez, Leticia Quintanilla-Martinez, Markus Bosmann, Hartmut Weiler, Wolfram Ruf

Blood (2024) 143 (10): 845–857.

https://doi.org/10.1182/blood.2023021149

Published: 2024

Includes: Supplemental data

Journal Articles

Hijacking of the Fibrinolytic System By B-Cell Acute Lymphoblastic Leukaemia and Its Therapeutic Targeting

Valentina Minciacchi, Christina Karantanou, Costanza Zanetti, Rahul Kumar, Theresa Krack, Nathalie Thomasberger, Pablo Llavona, Sylvia Hartmann, Veronique Maguer-Satta, Sylvain Lefort, Mateusz Putyrski, Andreas Ernst, Eshwar Meduri, Brian Huntly, Wolfram Ruf, Daniela S. Krause

Blood (2023) 142 (Supplement 1): 2781.

https://doi.org/10.1182/blood-2023-178811

Published: 2023

Journal Articles

Chronically Elevated Interleukin-6 Disturbs the Coagulation Cascade in Mice

Tanja Knopp, Jeremy Lagrange, Rebecca Jung, Johannes Wild, Heidi Rossmann, Henri M.H. Spronk, Thomas Wunderlich, Nadine Hoevelmeyer, Thomas Münzel, Bernhard Lämmle, Wolfram Ruf, Philip Wenzel, Ari Waisman, Susanne Helena Karbach

Blood (2021) 138 (Supplement 1): 2065.

https://doi.org/10.1182/blood-2021-149628

Published: 2021

Journal Articles

TLT-1 Regulates Thrombus Growth Under Non-Inflammatory Conditions

Angela Doerr, Denise Pedrosa, Maria Schander, Yotis A. Senis, Alexandra Mazharian, Anthony Valance Washington, Wolfram Ruf, Thomas Anthony Jude McKinnon

Blood (2021) 138 (Supplement 1): 1050.

https://doi.org/10.1182/blood-2021-152975

Published: 2021

Journal Articles

EPCR Signaling Controls the Activity of Hematopoietic Stem Cells Independent of Coagulation Regulation

Son Nguyen, Divij Verma, Claudine Graf, Shiri Gur-Cohen, Jennifer Royce, Naomi Esmon, Charles Esmon, Daniela S. Krause, Wolfram Ruf

Blood (2021) 138 (Supplement 1): 3263.

https://doi.org/10.1182/blood-2021-152673

Published: 2021

Journal Articles

Procoagulant activities of skeletal muscle and cardiac myosins require both myosin protein and myosin-associated anionic phospholipids

Shravan Morla, Hiroshi Deguchi, José A. Fernández, Wolfram Ruf, Rolf A. Brekken, John H. Griffin

Blood (2021) 137 (13): 1839–1842.

https://doi.org/10.1182/blood.2020008580

Published: 2021

Journal Articles

TRIF turns the switch for DIC in sepsis

Wolfram Ruf

Blood (2020) 135 (14): 1073–1074.

https://doi.org/10.1182/blood.2020004988

Published: 2020

Journal Articles

Links Between Complement Activation and Thrombosis

Wolfram Ruf, MD

Blood (2019) 134 (Supplement_1): SCI-40.

https://doi.org/10.1182/blood-2019-121113

Published: 2019

Journal Articles

Gpibα Engagement Induces Activation of Human Platelet TF and Association with Constitutively Platelet Surface-Bound FVIIa

Olga Panes, Biochemist, M. Francisca Becerra, Biochemist, Roger Valle, Biochemist, Claudia G Sáez, PhD, Patricia Hidalgo, MT, Jaime Pereira, MD, Jennifer Royce, Wolfram Ruf, MD, PhD, Diego Mezzano, MD

Blood (2019) 134 (Supplement_1): 2337.

https://doi.org/10.1182/blood-2019-126359

Published: 2019

Journal Articles

Tissue factor pathway inhibitor primes monocytes for antiphospholipid antibody-induced thrombosis

Nadine Müller-Calleja, Anne Hollerbach, Svenja Ritter, Denise G. Pedrosa, Dennis Strand, Claudine Graf, Christoph Reinhardt, Susanne Strand, Philippe Poncelet, John H. Griffin, Karl J. Lackner, Wolfram Ruf

Blood (2019) 134 (14): 1119–1131.

https://doi.org/10.1182/blood.2019001530

Published: 2019

Journal Articles

Macrophage Factor Xa Signaling Promotes Cancer Immune Evasion

Claudine Graf, MD PhD, Petra Wilgenbus, Maki Kitano, Stephan Macher-Göppinger, Wolfram Ruf, MD

Blood (2018) 132 (Supplement 1): 135.

https://doi.org/10.1182/blood-2018-99-119167

Published: 2018

Journal Articles

Integrin Alphav-beta3 on Podocytes Orchestrates Coagulation Protease Signaling through Protease-Activated Receptors

Madhusudhan Thati, PhD, Sanchita Ghosh, MS, Hongjie Wang, MD PhD, Wolfram Ruf, MD, Berend H. Isermann, MD

Blood (2018) 132 (Supplement 1): 137.

https://doi.org/10.1182/blood-2018-99-114566

Published: 2018

Journal Articles

Macrophage Protease-Activated Receptor 2 Regulates Fetal Liver Hematopoiesis in Mice

Mona Saffarzadeh, PhD, Wolfram Ruf, MD

Blood (2018) 132 (Supplement 1): 134.

https://doi.org/10.1182/blood-2018-99-112829

Published: 2018

Journal Articles

Extravascular coagulation in hematopoietic stem and progenitor cell regulation

T. Son Nguyen, Tsvee Lapidot, Wolfram Ruf

Blood (2018) 132 (2): 123–131.

https://doi.org/10.1182/blood-2017-12-768986

Published: 2018

Journal Articles

Paraoxonase-2 regulates coagulation activation through endothelial tissue factor

Julia Ebert, Petra Wilgenbus, John F. Teiber, Kerstin Jurk, Kathrin Schwierczek, Mareike Döhrmann, Ning Xia, Huige Li, Lisa Spiecker, Wolfram Ruf, Sven Horke

Blood (2018) 131 (19): 2161–2172.

https://doi.org/10.1182/blood-2017-09-807040

Published: 2018

Includes: Supplemental data

Journal Articles

Identification of the integrin-binding site on coagulation factor VIIa required for proangiogenic PAR2 signaling

Andrea S. Rothmeier, Enbo Liu, Sagarika Chakrabarty, Jennifer Disse, Barbara M. Mueller, Henrik Østergaard, Wolfram Ruf

Blood (2018) 131 (6): 674–685.

https://doi.org/10.1182/blood-2017-02-768218

Published: 2018

Journal Articles

Selective factor VIII activation by the tissue factor–factor VIIa–factor Xa complex

Yuichi Kamikubo, G. Loredana Mendolicchio, Antonella Zampolli, Patrizia Marchese, Andrea S. Rothmeier, Jennifer Nagrampa Orje, Andrew J. Gale, Sriram Krishnaswamy, András Gruber, Henrik Østergaard, Lars C. Petersen, Wolfram Ruf, Zaverio M. Ruggeri

Blood (2017) 130 (14): 1661–1670.

https://doi.org/10.1182/blood-2017-02-767079

Published: 2017

Includes: Supplemental data

NARROW

Saliva of persons with hemophilia A triggers coagulation via extrinsic tenase complexes

Barrier disruption by coagulation FXIa

Targeting the tissue factor coagulation initiation complex prevents antiphospholipid antibody development

Nucleic acid sensing promotes inflammatory monocyte migration through biased coagulation factor VIIa signaling

Hijacking of the Fibrinolytic System By B-Cell Acute Lymphoblastic Leukaemia and Its Therapeutic Targeting

Chronically Elevated Interleukin-6 Disturbs the Coagulation Cascade in Mice

TLT-1 Regulates Thrombus Growth Under Non-Inflammatory Conditions

EPCR Signaling Controls the Activity of Hematopoietic Stem Cells Independent of Coagulation Regulation

Procoagulant activities of skeletal muscle and cardiac myosins require both myosin protein and myosin-associated anionic phospholipids

TRIF turns the switch for DIC in sepsis

Links Between Complement Activation and Thrombosis

Gpibα Engagement Induces Activation of Human Platelet TF and Association with Constitutively Platelet Surface-Bound FVIIa

Tissue factor pathway inhibitor primes monocytes for antiphospholipid antibody-induced thrombosis

Macrophage Factor Xa Signaling Promotes Cancer Immune Evasion

Integrin Alphav-beta3 on Podocytes Orchestrates Coagulation Protease Signaling through Protease-Activated Receptors

Macrophage Protease-Activated Receptor 2 Regulates Fetal Liver Hematopoiesis in Mice

Extravascular coagulation in hematopoietic stem and progenitor cell regulation

Paraoxonase-2 regulates coagulation activation through endothelial tissue factor

Identification of the integrin-binding site on coagulation factor VIIa required for proangiogenic PAR2 signaling

Selective factor VIII activation by the tissue factor–factor VIIa–factor Xa complex

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American Society of Hematology

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American Society of Hematology

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