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Journal Articles

TLT-1 Regulates Thrombus Growth Under Non-Inflammatory Conditions

Angela Doerr, Denise Pedrosa, Maria Schander, Yotis A. Senis, Alexandra Mazharian, Anthony Valance Washington, Wolfram Ruf, Thomas Anthony Jude McKinnon

Blood (2021) 138 (Supplement 1): 1050.

https://doi.org/10.1182/blood-2021-152975

Published: 2021

Journal Articles

Interplay between the tyrosine kinases Chk and Csk and phosphatase PTPRJ is critical for regulating platelets in mice

Zoltan Nagy, Jun Mori, Vanesa-Sindi Ivanova, Alexandra Mazharian, Yotis A. Senis

Blood (2020) 135 (18): 1574–1587.

https://doi.org/10.1182/blood.2019002848

Published: 2020

Includes: Supplemental data

Journal Articles

Catalytic dysregulation of SHP2 leading to Noonan syndromes affects platelet signaling and functions

Marie Bellio, Cédric Garcia, Thomas Edouard, Sophie Voisin, Benjamin G. Neel, Cendrine Cabou, Philippe Valet, Jun Mori, Alexandra Mazharian, Yotis A. Senis, Armelle Yart, Bernard Payrastre, Sonia Severin

Blood (2019) 134 (25): 2304–2317.

https://doi.org/10.1182/blood.2019001543

Published: 2019

Includes: Supplemental data

Journal Articles

Megakaryocyte-Driven Myelofibrosis Leads to Progressive Osteosclerosis in G6b-B Knockout Mice

Mariya Stavnichuk, BSc, Zoltan Nagy, Yotis A. Senis, Svetlana V. Komarova

Blood (2019) 134 (Supplement_1): 4199.

https://doi.org/10.1182/blood-2019-124186

Published: 2019

Journal Articles

The Gp1ba-Cre transgenic mouse: a new model to delineate platelet and leukocyte functions

Zoltan Nagy, Timo Vögtle, Mitchell J. Geer, Jun Mori, Silke Heising, Giada Di Nunzio, Ralph Gareus, Alexander Tarakhovsky, Arthur Weiss, Benjamin G. Neel, Guillaume E. Desanti, Alexandra Mazharian, Yotis A. Senis

Blood (2019) 133 (4): 331–343.

https://doi.org/10.1182/blood-2018-09-877787

Published: 2019

Includes: Supplemental data

Journal Articles

TLT-1: please release me, let me go

Yotis A. Senis

Blood (2018) 132 (23): 2427–2429.

https://doi.org/10.1182/blood-2018-10-879676

Published: 2018

Journal Articles

Uncoupling ITIM receptor G6b-B from tyrosine phosphatases Shp1 and Shp2 disrupts murine platelet homeostasis

Mitchell J. Geer, Johanna P. van Geffen, Piraveen Gopalasingam, Timo Vögtle, Christopher W. Smith, Silke Heising, Marijke J. E. Kuijpers, Bibian M. E. Tullemans, Gavin E. Jarvis, Johannes A. Eble, Mark Jeeves, Michael Overduin, Johan W. M. Heemskerk, Alexandra Mazharian, Yotis A. Senis

Blood (2018) 132 (13): 1413–1425.

https://doi.org/10.1182/blood-2017-10-802975

Published: 2018

Includes: Supplemental data

Journal Articles

Congenital macrothrombocytopenia with focal myelofibrosis due to mutations in human G6b-B is rescued in humanized mice

Blood (2018) 132 (13): 1399–1412.

https://doi.org/10.1182/blood-2017-08-802769

Published: 2018

Includes: Supplemental data

Journal Articles

Maintenance of murine platelet homeostasis by the kinase Csk and phosphatase CD148

Blood (2018) 131 (10): 1122–1144.

https://doi.org/10.1182/blood-2017-02-768077

Published: 2018

Includes: Multimedia, Supplemental data

Journal Articles

Congenital Thrombocytopenia and Myelofibrosis Due to Germline Mutations in G6b-B— a Megakaryocyte-Specific Immunoreceptor Tyrosine-Based Inhibitory Motif (ITIM) Receptor

Inga Hofmann, MD, Andrew Crispin, BS, Dean Campagna, BS, Monica Calicchio, Klaus Schmitz-Abe, Esther A. Obeng, MD PhD, Kyriacos Markianos, Yotis A. Senis, Mark D. Fleming, MD DPhil

Blood (2017) 130 (Supplement 1): 1630.

https://doi.org/10.1182/blood.V130.Suppl_1.1630.1630

Published: 2017

Journal Articles

ITIM receptors: more than just inhibitors of platelet activation

Carmen H. Coxon, Mitchell J. Geer, Yotis A. Senis

Blood (2017) 129 (26): 3407–3418.

https://doi.org/10.1182/blood-2016-12-720185

Published: 2017

Includes: Supplemental data

Journal Articles

Ups and downs of the ADP phosphoproteome

Zoltan Nagy, Yotis A. Senis

Blood (2017) 129 (2): 135–136.

https://doi.org/10.1182/blood-2016-11-751917

Published: 2017

Journal Articles

Proplatelets slip slidin’ away

Alexandra Mazharian, Yotis A. Senis

Blood (2015) 125 (5): 747–748.

https://doi.org/10.1182/blood-2014-12-614131

Published: 2015

Journal Articles

Src family kinases: at the forefront of platelet activation

Yotis A. Senis, Alexandra Mazharian, Jun Mori

Blood (2014) 124 (13): 2013–2024.

https://doi.org/10.1182/blood-2014-01-453134

Published: 2014

Journal Articles

Megakaryocyte-specific deletion of the protein-tyrosine phosphatases Shp1 and Shp2 causes abnormal megakaryocyte development, platelet production, and function

Alexandra Mazharian, Jun Mori, Ying-Jie Wang, Silke Heising, Benjamin G. Neel, Steve P. Watson, Yotis A. Senis

Blood (2013) 121 (20): 4205–4220.

https://doi.org/10.1182/blood-2012-08-449272

Published: 2013

Includes: Multimedia, Supplemental data

Journal Articles

The tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosis

Yotis A. Senis, Michael G. Tomlinson, Stuart Ellison, Alexandra Mazharian, Jenson Lim, Yan Zhao, Kristin N. Kornerup, Jocelyn M. Auger, Steve G. Thomas, Tarvinder Dhanjal, Neena Kalia, Jing W. Zhu, Arthur Weiss, Steve P. Watson

Blood (2009) 113 (20): 4942–4954.

https://doi.org/10.1182/blood-2008-08-174318

Published: 2009

Includes: Multimedia, Supplemental data

Journal Articles

GPIb-dependent platelet activation is dependent on Src kinases but not MAP kinase or cGMP-dependent kinase

Stuart J. Marshall, Yotis A. Senis, Jocelyn M. Auger, Robert Feil, Franz Hofmann, Gary Salmon, J. Thomas Peterson, Frank Burslem, Steve P. Watson

Blood (2004) 103 (7): 2601–2609.

https://doi.org/10.1182/blood-2003-09-3319

Published: 2004

Journal Articles

GPVI levels in platelets: relationship to platelet function at high shear

Denise Best, Yotis A. Senis, Gavin E. Jarvis, Helen J. Eagleton, David J. Roberts, Takashi Saito, Stephanie M. Jung, Masaaki Moroi, Paul Harrison, Fiona R. Green, Steve P. Watson

Blood (2003) 102 (8): 2811–2818.

https://doi.org/10.1182/blood-2003-01-0231

Published: 2003

NARROW

TLT-1 Regulates Thrombus Growth Under Non-Inflammatory Conditions

Interplay between the tyrosine kinases Chk and Csk and phosphatase PTPRJ is critical for regulating platelets in mice

Catalytic dysregulation of SHP2 leading to Noonan syndromes affects platelet signaling and functions

Megakaryocyte-Driven Myelofibrosis Leads to Progressive Osteosclerosis in G6b-B Knockout Mice

The Gp1ba-Cre transgenic mouse: a new model to delineate platelet and leukocyte functions

TLT-1: please release me, let me go

Uncoupling ITIM receptor G6b-B from tyrosine phosphatases Shp1 and Shp2 disrupts murine platelet homeostasis

Congenital macrothrombocytopenia with focal myelofibrosis due to mutations in human G6b-B is rescued in humanized mice

Maintenance of murine platelet homeostasis by the kinase Csk and phosphatase CD148

Congenital Thrombocytopenia and Myelofibrosis Due to Germline Mutations in G6b-B— a Megakaryocyte-Specific Immunoreceptor Tyrosine-Based Inhibitory Motif (ITIM) Receptor

ITIM receptors: more than just inhibitors of platelet activation

Ups and downs of the ADP phosphoproteome

Proplatelets slip slidin’ away

Src family kinases: at the forefront of platelet activation

Megakaryocyte-specific deletion of the protein-tyrosine phosphatases Shp1 and Shp2 causes abnormal megakaryocyte development, platelet production, and function

The tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosis

GPIb-dependent platelet activation is dependent on Src kinases but not MAP kinase or cGMP-dependent kinase

GPVI levels in platelets: relationship to platelet function at high shear

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American Society of Hematology

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ASH Publications

American Society of Hematology

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