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Journal Articles

First-Line Venetoclax and a Hypomethylating Agent or Conventional Chemotherapy in Older Adults with IDH -Mutated AML

Ian Bouligny, Graeme Murray, Thuy Ho, Juhi Gor, Kyle Zacholski, Nolan Wages, Steven Grant, Keri Maher
Journal: Blood
Blood (2023) 142 (Supplement 1): 1488.
https://doi.org/10.1182/blood-2023-188400
Published: 2023
Journal Articles

Validation of the Charlson Comorbidity Index Model in Acute Myeloid Leukemia Treated with a Hypomethylating Agent and Venetoclax

Ian Bouligny, Graeme Murray, Thuy Ho, Juhi Gor, Kyle Zacholski, Nolan Wages, Steven Grant, Keri Maher
Journal: Blood
Blood (2023) 142 (Supplement 1): 5093.
https://doi.org/10.1182/blood-2023-189322
Published: 2023
Journal Articles

The Impact of Delayed Venetoclax Initiation on Overall Survival in Acute Myeloid Leukemia

Ian Bouligny, Graeme Murray, Thuy Ho, Juhi Gor, Kyle Zacholski, Nolan Wages, Steven Grant, Keri Maher
Journal: Blood
Blood (2023) 142 (Supplement 1): 4233.
https://doi.org/10.1182/blood-2023-188249
Published: 2023
Journal Articles

CPX-351 Versus FLAG-IDA with or without Venetoclax in Previously Untreated and Relapsed or Refractory Acute Myeloid Leukemia

Ian Bouligny, Graeme Murray, Thuy Ho, Juhi Gor, Kyle Zacholski, Nolan Wages, Steven Grant, Keri Maher
Journal: Blood
Blood (2023) 142 (Supplement 1): 4269.
https://doi.org/10.1182/blood-2023-189184
Published: 2023
Journal Articles

Phase 1 Pharmacodynamic and Pharmacokinetic Study of the Geranylgeranyltransferase I Inhibitor PTX-100 (GGTI-2418) in Patients with Advanced Malignancies

Terrence Chew, Costas K. Yannakou, Vinod Ganju, Steven Grant, Said Sebti, H. Miles Prince
Journal: Blood
Blood (2023) 142 (Supplement 1): 1705.
https://doi.org/10.1182/blood-2023-179411
Published: 2023
Journal Articles

CUX1 mut Acute Myeloid Leukemia As a Distinct Biological Entity: An Analysis of Clinical Outcomes and Implications

Ian Bouligny, Graeme Murray, Thuy Ho, Juhi Gor, Kyle Zacholski, Nolan Wages, Steven Grant, Keri Maher
Journal: Blood
Blood (2023) 142 (Supplement 1): 5978.
https://doi.org/10.1182/blood-2023-189407
Published: 2023
Journal Articles

Comparison of Response and Survival with Chemotherapy and Targeted Therapies between IDH mut Isoforms in Acute Myeloid Leukemia

Ian Bouligny, Graeme Murray, Thuy Ho, Juhi Gor, Kyle Zacholski, Nolan Wages, Steven Grant, Keri Maher
Journal: Blood
Blood (2023) 142 (Supplement 1): 6010.
https://doi.org/10.1182/blood-2023-188362
Published: 2023
Journal Articles

FLT3 Inhibitors in Combination with FLAG-IDA in Relapsed or Refractory Acute Myeloid Leukemia

Ian Bouligny, Graeme Murray, Thuy Ho, Juhi Gor, Kyle Zacholski, Nolan Wages, Steven Grant, Keri Maher
Journal: Blood
Blood (2023) 142 (Supplement 1): 5920.
https://doi.org/10.1182/blood-2023-188333
Published: 2023
Journal Articles

The Molecular Landscape of Acute Myeloid Leukemia with Trisomy 8: A Comprehensive Cancer Center Analysis of 627 Patients

Ian Bouligny, Graeme Murray, Thuy Ho, Juhi Gor, Kyle Zacholski, Nolan Wages, Steven Grant, Keri Maher
Journal: Blood
Blood (2023) 142 (Supplement 1): 6053.
https://doi.org/10.1182/blood-2023-189260
Published: 2023
Journal Articles

Revisiting Ratify: Daunorubicin 60 Mg/m 2 Vs 90 Mg/m 2 in Previously Untreated FLT3 mut Acute Myeloid Leukemia

Ian Bouligny, Graeme Murray, Thuy Ho, Juhi Gor, Kyle Zacholski, Nolan Wages, Steven Grant, Keri Maher
Journal: Blood
Blood (2023) 142 (Supplement 1): 5912.
https://doi.org/10.1182/blood-2023-189138
Published: 2023
Journal Articles

Randomized Phase II Study to Assess the Role of Nivolumab As Single Agent to Eliminate Minimal Residual Disease and Maintain Remission in Acute Myelogenous Leukemia (AML) Patients after Chemotherapy (NCI9706 protocol; REMAIN Trial)

Hongtao Liu, Elad Sharon, Theodore G. Karrison, Yuanyuan Zha, Noreen Fulton, Howard Streicher, Kendra Sweet, George Yaghmour, Jane Jijun Liu, Brian A. Jonas, Aaron D. Schimmer, Steven Grant, Amer M. Zeidan, Gerhard C. Hildebrandt, Christopher S. Hourigan, Christopher H. Lowrey, Ryan J. Mattison, Neil Palmisiano, Amandeep Salhotra, Dimitrios Tzachanis, Maria R. Baer, Tara L. Lin, Prapti Patel, Helen Chen, Walter M. Stadler, Olatoyosi Odenike, Richard A. Larson, Thomas F. Gajewski, Wendy Stock
Journal: Blood
Blood (2022) 140 (Supplement 1): 1716–1719.
https://doi.org/10.1182/blood-2022-157326
Published: 2022
Journal Articles

Acid Ceramidase (ASAH1) Is a Key Mediator of Drug Resistance in Refractory Multiple Myeloma

Ryan T Bishop, Tao Li, Raghunandan Reddy Alugubelli, Mark Meads, Bin Fang, Gabriel De Avila, Oliver Hampton, Steven Grant, John M. Koomen, Ariosto Siqueira Silva, Kenneth H. Shain, Conor Lynch
Journal: Blood
Blood (2022) 140 (Supplement 1): 5977–5978.
https://doi.org/10.1182/blood-2022-170103
Published: 2022
Journal Articles

Acid Ceramidase (ASAH1) Mediates Intrinsic and Intercellular Transfer of Proteasome Inhibitor Resistance in Multiple Myeloma

Ryan T Bishop, Tao Li, Raghunandan R Alugubelli, Oliver Hampton, Ariosto Siqueira Silva, Steven Grant, Kenneth H. Shain, Conor C Lynch
Journal: Blood
Blood (2021) 138 (Supplement 1): 1206.
https://doi.org/10.1182/blood-2021-152686
Published: 2021
Journal Articles

Targeting cereblon in AML

Steven Grant
Journal: Blood
Blood (2021) 137 (5): 584–586.
https://doi.org/10.1182/blood.2020009827
Published: 2021
Journal Articles

Modeling Marginal Zone Lymphomagenesis

Victor Yazbeck, MD, Ian McConnell, Emily Harris, Joseph Lownik, Ariel Sindel, DO, Roy Sabo, PhD, Alden Chesney, MD, Guanhua Lai, MD PhD, Adolfo Mauro, PhD, Chad Cain, Fadi N. Salloum, Jamal Zweit, PhD, Steven Grant, MD, Jolene Windle, PhD, Steven Grossman, MD
Journal: Blood
Blood (2020) 136 (Supplement 1): 31.
https://doi.org/10.1182/blood-2020-142768
Published: 2020
Journal Articles

Role of the PI3K Pathway in the Pathogenesis of Marginal Zone Lymphoma

Ariel Sindel, DO, Ian McConnell, MS, Jolene Windle, PhD, Roy Sabo, PhD, Alden Chesney, MD, Guanhua Lai, MD PhD, Adolfo Mauro, PhD, Taha Al-Juhaishi, MD, Mohamed Rahmani, PhD, Jamal Zweit, PhD, Steven Grant, MD, Steven Grossman, MD, Victor Youssef Yazbeck, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4125.
https://doi.org/10.1182/blood-2018-99-111284
Published: 2018
Journal Articles

R-spondin(g) to syndecan-1 in myeloma

Steven Grant
Journal: Blood
Blood (2018) 131 (9): 946–947.
https://doi.org/10.1182/blood-2017-12-821504
Published: 2018
Journal Articles

Alvocidib Enhances Venetoclax Sensitivity in Unfavorable-Risk Multiple Myeloma Cells In Vitro and In Vivo

Liang Zhou, PhD, Yu Zhang, PhD, Deepak Sampath, PhD, Joel D. Leverson, PhD, Yun Dai, MD, Maciej Kmieciak, Matthew Nguyen, Robert Z. Orlowski, MD PhD, Steven Grant, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2540.
https://doi.org/10.1182/blood.V130.Suppl_1.2540.2540
Published: 2017
Journal Articles

Gls Inhibitor CB-839 Modulates Cellular Metabolism in AML and Potently Suppresses AML Cell Growth When Combined with 5-Azacitidine

Tianyu Cai, PhD, Philip L Lorenzi, PhD, Dinesh Rakheja, MD, Michael A Pontikos, Alessia Lodi, Lina Han, MD PhD, Qi Zhang, MD PhD, Helen Ma, MS, Mohamed Rahmani, PhD, Tushar Damodar Bhagat, PhD, Thomas D Horvath, PhD, Courtney D. DiNardo, MD MSCE, Steven Grant, MD, Stefano Tiziani, PhD, Amit Verma, MD, Marina Konopleva, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4064.
https://doi.org/10.1182/blood.V128.22.4064.4064
Published: 2016
Journal Articles

Combination Therapy with Bortezomib or Carfilzomib and Selinexor Induces Nuclear Localization of Ikbα and Overcomes Acquired Proteasome Inhibitor Resistance in Human Multiple Myeloma

Joel G Turner, PhD, Trinayan Kashyap, MS, Jana L Dawson, BS, Juan A Gomez, BS, Alexis Bauer, BS, Steven Grant, MD, Yun Dai, PhD, Kenneth H. Shain, MD PhD, Mark B Meads, PhD, Yosef Landesman, PhD, Daniel M Sullivan, MD
Journal: Blood
Blood (2016) 128 (22): 3299.
https://doi.org/10.1182/blood.V128.22.3299.3299
Published: 2016