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Volume 108, Issue 3

August 1 2006

In this Issue

INSIDE BLOOD
BLOOD WORK
PLENARY PAPERS
PERSPECTIVES
REVIEW ARTICLES
CHEMOKINES, CYTOKINES, AND INTERLEUKINS
CLINICAL TRIALS AND OBSERVATIONS
GENE THERAPY
HEMATOPOIESIS
HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY
IMMUNOBIOLOGY
NEOPLASIA
RED CELLS
STEM CELLS IN HEMATOLOGY
TRANSPLANTATION
CORRESPONDENCE

INSIDE BLOOD

RED CELLS

Deep mining of the RBC proteome

David W. Speicher

View Articletitled, Deep mining of the RBC proteome

CLINICAL TRIALS AND OBSERVATIONS

RIC for MDS: the glass is half full
Clinical Trials & Observations

David L. Porter

View Articletitled, RIC for MDS: the glass is half full

HEMATOPOIESIS

Cell-cycle control in erythropoiesis

Marieke von Lindern

View Articletitled, Cell-cycle control in erythropoiesis

HEMOSTASIS

Quinine: common remedy, serious reactions, new insights

James N. George

View Articletitled, Quinine: common remedy, serious reactions, new insights

RED CELLS

Hemoglobin F: new targets, new path

Susan P. Perrine

View Articletitled, Hemoglobin F: new targets, new path

IMMUNOBIOLOGY

Macrophage activation:'tis the way the WNT blows

Jeff Schorey

View Articletitled, Macrophage activation:'tis the way the WNT blows

NEOPLASIA

Colonel Mustard, with the rope, in the ballroom

Bruce M. Camitta

View Articletitled, Colonel Mustard, with the rope, in the ballroom

NEOPLASIA

HTLV-I and AZT: die another day

Renaud Mahieux

View Articletitled, HTLV-I and AZT: die another day

TRANSPLANTATION

Never say never again!

Jane F. Apperley

View Articletitled, Never say never again!

NEOPLASIA

Glucocorticoid resistance: a persistent riddle

Bruce M. Camitta

View Articletitled, Glucocorticoid resistance: a persistent riddle

BLOOD WORK

Cancer, anemia, and fever

View Articletitled, Cancer, anemia, and fever

PLENARY PAPERS

In-depth analysis of the membrane and cytosolic proteome of red blood cells

Erica M. Pasini,Morten Kirkegaard,Peter Mortensen,Hans U. Lutz,Alan W. Thomas,Matthias Mann

View Articletitled, In-depth analysis of the membrane and cytosolic proteome of red blood cells

Supplemental data

PERSPECTIVES

Low-dose therapy trumps high-dose therapy again in the treatment of Gaucher disease

Ari Zimran,Deborah Elstein,Ernest Beutler

View Articletitled, Low-dose therapy trumps high-dose therapy again in the treatment of Gaucher disease

REVIEW ARTICLES

Regulatory T cells in cancer

Marc Beyer,Joachim L. Schultze

View Articletitled, Regulatory T cells in cancer

CHEMOKINES, CYTOKINES, AND INTERLEUKINS

G-CSF down-regulation of CXCR4 expression identified as a mechanism for mobilization of myeloid cells

Hyun Kyung Kim,Maria De La Luz Sierra,Cassin Kimmel Williams,A. Virginia Gulino,Giovanna Tosato

View Articletitled, G-CSF down-regulation of CXCR4 expression identified as a mechanism for mobilization of myeloid cells

RAX, the PKR activator, sensitizes cells to inflammatory cytokines, serum withdrawal, chemotherapy, and viral infection

Richard L. Bennett,William L. Blalock,Dean M. Abtahi,Yu Pan,Sue A. Moyer,W. Stratford May

View Articletitled, RAX, the PKR activator, sensitizes cells to inflammatory cytokines, serum withdrawal, chemotherapy, and viral infection

CLINICAL TRIALS AND OBSERVATIONS

Superior effects of high-dose enzyme replacement therapy in type 1 Gaucher disease on bone marrow involvement and chitotriosidase levels: a 2-center retrospective analysis
Clinical Trials & Observations

Maaike de Fost,Carla E. M. Hollak,Johanna E. M. Groener,Johannes M. F. G. Aerts,Mario Maas,Ludger W. Poll,Maaike G. Wiersma,Dieter Häussinger,Sarah Brett,Nicole Brill,Stephan vom Dahl

View Articletitled, Superior effects of high-dose enzyme replacement therapy in type 1 Gaucher disease on bone marrow involvement and chitotriosidase levels: a 2-center retrospective analysis

Retrospective comparison of reduced-intensity conditioning and conventional high-dose conditioning for allogeneic hematopoietic stem cell transplantation using HLA-identical sibling donors in myelodysplastic syndromes
Clinical Trials & Observations

Rodrigo Martino,Simona Iacobelli,Ronald Brand,Thekla Jansen,Anja van Biezen,Jürgen Finke,Andrea Bacigalupo,Dietrich Beelen,Jossy Reiffers,Agnes Devergie,Emilie Alessandrino,Ghulam J. Mufti,Renée Barge,Jorge Sierra,Tapani Ruutu,Marc Boogaerts,Michele Falda,Jean-Pierre Jouet,Dieter Niederwieser,Theo de Witte,for the Myelodysplastic Syndrome subcommittee of the Chronic Leukemia Working Party of the European Blood and Marrow Transplantation Group

View Articletitled, Retrospective comparison of reduced-intensity conditioning and conventional high-dose conditioning for allogeneic hematopoietic stem cell transplantation using HLA-identical sibling donors in myelodysplastic syndromes

Stroke Prevention Trial in Sickle Cell Anemia (STOP): extended follow-up and final results
Clinical Trials & Observations

Margaret T. Lee,Sergio Piomelli,Suzanne Granger,Scott T. Miller,Shannon Harkness,Donald J. Brambilla,Robert J. Adams,for the STOP Study Investigators

View Articletitled, Stroke Prevention Trial in Sickle Cell Anemia (STOP): extended follow-up and final results

Clinical significance of ZAP-70 protein expression in B-cell chronic lymphocytic leukemia
Clinical Trials & Observations

Maria Ilaria Del Principe,Giovanni Del Poeta,Francesco Buccisano,Luca Maurillo,Adriano Venditti,Antonella Zucchetto,Rita Marini,Pasquale Niscola,Maria Antonietta Irno Consalvo,Carla Mazzone,Licia Ottaviani,Paola Panetta,Antonio Bruno,Riccardo Bomben,Giovanna Suppo,Massimo Degan,Valter Gattei,Paolo de Fabritiis,Maria Cantonetti,Francesco Lo Coco,Domenico Del Principe,Sergio Amadori

View Articletitled, Clinical significance of ZAP-70 protein expression in B-cell chronic lymphocytic leukemia

GENE THERAPY

Correction of a murine model of von Willebrand disease by gene transfer

Robert G. Pergolizzi,Guangchun Jin,Diane Chan,Lorraine Pierre,James Bussel,Barbara Ferris,Philip L. Leopold,Ronald G. Crystal

View Articletitled, Correction of a murine model of von Willebrand disease by gene transfer

Targeting self-antigens through allogeneic TCR gene transfer

Moniek A. de Witte,Miriam Coccoris,Monika C. Wolkers,Marly D. van den Boom,Elly M. Mesman,Ji-Ying Song,Martin van der Valk,John B. A. G. Haanen,Ton N. M. Schumacher

View Articletitled, Targeting self-antigens through allogeneic TCR gene transfer

Supplemental data

HEMATOPOIESIS

Mouse plasmacytoid dendritic cells derive exclusively from estrogen-resistant myeloid progenitors

Benjamin C. Harman,Juli P. Miller,Neda Nikbakht,Rachel Gerstein,David Allman

View Articletitled, Mouse plasmacytoid dendritic cells derive exclusively from estrogen-resistant myeloid progenitors

E2f4 regulates fetal erythropoiesis through the promotion of cellular proliferation

Kathryn M. Kinross,Allison J. Clark,Rosa M. Iazzolino,Patrick Orson Humbert

View Articletitled, E2f4 regulates fetal erythropoiesis through the promotion of cellular proliferation

Supplemental data

Proper levels of c-Myb are discretely defined at distinct steps of hematopoietic cell development

Hiroshi Sakamoto,Guoyou Dai,Kaori Tsujino,Kazuaki Hashimoto,Xin Huang,Tetsuhiro Fujimoto,Michael Mucenski,Jon Frampton,Minetaro Ogawa

View Articletitled, Proper levels of c-Myb are discretely defined at distinct steps of hematopoietic cell development

Supplemental data

Identification of the nonreceptor tyrosine kinase MATK/CHK as an essential regulator of immune cells using Matk/CHK-deficient mice
Brief Report

Byeong-Chel Lee,Shalom Avraham,Akira Imamoto,Hava Karsenty Avraham

View Articletitled, Identification of the nonreceptor tyrosine kinase MATK/CHK as an essential regulator of immune cells using Matk/CHK-deficient mice

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Activation-independent, antibody-mediated removal of GPVI from circulating human platelets: development of a novel NOD/SCID mouse model to evaluate the in vivo effectiveness of anti–human platelet agents

Brian Boylan,Michael C. Berndt,Mark L. Kahn,Peter J. Newman

View Articletitled, Activation-independent, antibody-mediated removal of GPVI from circulating human platelets: development of a novel NOD/SCID mouse model to evaluate the in vivo effectiveness of anti–human platelet agents

Endothelial progenitor cells from infantile hemangioma and umbilical cord blood display unique cellular responses to endostatin

Zia A. Khan,Juan M. Melero-Martin,Xiao Wu,Sailaja Paruchuri,Elisa Boscolo,John B. Mulliken,Joyce Bischoff

View Articletitled, Endothelial progenitor cells from infantile hemangioma and umbilical cord blood display unique cellular responses to endostatin

Patients with quinine-induced immune thrombocytopenia have both “drug-dependent” and “drug-specific” antibodies

Daniel W. Bougie,Peter R. Wilker,Richard H. Aster

View Articletitled, Patients with quinine-induced immune thrombocytopenia have both “drug-dependent” and “drug-specific” antibodies

Platelet-derived LIGHT induces inflammatory responses in endothelial cells and monocytes

Kari Otterdal,Camilla Smith,Erik Øie,Turid M. Pedersen,Arne Yndestad,Espen Stang,Knut Endresen,Nils O. Solum,Pål Aukrust,Jan K. Damås

View Articletitled, Platelet-derived LIGHT induces inflammatory responses in endothelial cells and monocytes

Structural basis for platelet collagen responses by the immune-type receptor glycoprotein VI

Katsunori Horii,Mark L. Kahn,Andrew B. Herr

View Articletitled, Structural basis for platelet collagen responses by the immune-type receptor glycoprotein VI

Supplemental data

Relative efficacy of intravenous immunoglobulin G in ameliorating thrombocytopenia induced by antiplatelet GPIIbIIIa versus GPIbα antibodies
Brief Report

Michelle Lee Webster,Ebrahim Sayeh,Min Crow,Pingguo Chen,Bernhard Nieswandt,John Freedman,Heyu Ni

View Articletitled, Relative efficacy of intravenous immunoglobulin G in ameliorating thrombocytopenia induced by antiplatelet GPIIbIIIa versus GPIbα antibodies

IMMUNOBIOLOGY

The apoptotic-cell receptor CR3, but not αvβ5, is a regulator of human dendritic-cell immunostimulatory function

Mojca Škoberne,Selin Somersan,Wanda Almodovar,Tuan Truong,Kseniya Petrova,Peter M. Henson,Nina Bhardwaj

View Articletitled, The apoptotic-cell receptor CR3, but not αvβ5, is a regulator of human dendritic-cell immunostimulatory function

Supplemental data

Phospholipase D2 acts as an essential adaptor protein in the activation of Syk in antigen-stimulated mast cells

Jun Ho Lee,Young Mi Kim,Nam Wook Kim,Jie Wan Kim,Erk Her,Bo Kyung Kim,Jong Hyun Kim,Sung Ho Ryu,Jong Woo Park,Dong Wan Seo,Jeung Whan Han,Michael A. Beaven,Wahn Soo Choi

View Articletitled, Phospholipase D2 acts as an essential adaptor protein in the activation of Syk in antigen-stimulated mast cells

The Wingless homolog WNT5A and its receptor Frizzled-5 regulate inflammatory responses of human mononuclear cells induced by microbial stimulation

Antje Blumenthal,Stefan Ehlers,Jörg Lauber,Jan Buer,Christoph Lange,Torsten Goldmann,Holger Heine,Ernst Brandt,Norbert Reiling

View Articletitled, The Wingless homolog WNT5A and its receptor Frizzled-5 regulate inflammatory responses of human mononuclear cells induced by microbial stimulation

Supplemental data

Autoreactive MZ and B-1 B-cell activation by Fas^lpr is coincident with an increased frequency of apoptotic lymphocytes and a defect in macrophage clearance

Ye Qian,Kara L. Conway,Xiangdong Lu,Heather M. Seitz,Glenn K. Matsushima,Stephen H. Clarke

View Articletitled, Autoreactive MZ and B-1 B-cell activation by Faslpr is coincident with an increased frequency of apoptotic lymphocytes and a defect in macrophage clearance

Proprotein convertase furin is preferentially expressed in T helper 1 cells and regulates interferon gamma
Brief Report

Marko Pesu,Linda Muul,Yuka Kanno,John J. O'Shea

View Articletitled, Proprotein convertase furin is preferentially expressed in T helper 1 cells and regulates interferon gamma

Supplemental data

NEOPLASIA

Transcriptional regulatory networks downstream of TAL1/SCL in T-cell acute lymphoblastic leukemia

Teresa Palomero,Duncan T. Odom,Jennifer O'Neil,Adolfo A. Ferrando,Adam Margolin,Donna S. Neuberg,Stuart S. Winter,Richard S. Larson,Wei Li,X. Shirley Liu,Richard A. Young,A. Thomas Look

View Articletitled, Transcriptional regulatory networks downstream of TAL1/SCL in T-cell acute lymphoblastic leukemia

Supplemental data

Mdm2 inhibitor Nutlin-3a induces p53-mediated apoptosis by transcription-dependent and transcription-independent mechanisms and may overcome Atm-mediated resistance to fludarabine in chronic lymphocytic leukemia

Kensuke Kojima,Marina Konopleva,Teresa McQueen,Susan O'Brien,William Plunkett,Michael Andreeff

View Articletitled, Mdm2 inhibitor Nutlin-3a induces p53-mediated apoptosis by transcription-dependent and transcription-independent mechanisms and may overcome Atm-mediated resistance to fludarabine in chronic lymphocytic leukemia

Plasma thrombopoietin compared with immunoglobulin heavy-chain mutation status as a predictor of survival in chronic lymphocytic leukemia
Clinical Trials & Observations

Charles Koller,B. Nebiyou Bekele,Xian Zhou,Charles Park,Zeev Estrov,Susan O'Brien,Michael Keating,Iman Jilani,Francis J. Giles,Hagop M. Kantarjian,Maher Albitar

View Articletitled, Plasma thrombopoietin compared with immunoglobulin heavy-chain mutation status as a predictor of survival in chronic lymphocytic leukemia

Effective treatment of a murine model of adult T-cell leukemia using ²¹¹At-7G7/B6 and its combination with unmodified anti-Tac (daclizumab) directed toward CD25

Zhuo Zhang,Meili Zhang,Kayhan Garmestani,Vladimir S. Talanov,Paul S. Plascjak,Barbara Beck,Carolyn Goldman,Martin W. Brechbiel,Thomas A. Waldmann

View Articletitled, Effective treatment of a murine model of adult T-cell leukemia using 211At-7G7/B6 and its combination with unmodified anti-Tac (daclizumab) directed toward CD25

Aberrant somatic hypermutation in tumor cells of nodular-lymphocyte–predominant and classic Hodgkin lymphoma

Arcangelo Liso,Daniela Capello,Teresa Marafioti,Enrico Tiacci,Michaela Cerri,Verena Distler,Marco Paulli,Antonino Carbone,Georges Delsol,Elias Campo,Stefano Pileri,Laura Pasqualucci,Gianluca Gaidano,Brunangelo Falini

View Articletitled, Aberrant somatic hypermutation in tumor cells of nodular-lymphocyte–predominant and classic Hodgkin lymphoma

Supplemental data

Persistent inhibition of telomerase reprograms adult T-cell leukemia to p53-dependent senescence

Abhik Datta,Marcia Bellon,Uma Sinha-Datta,Ali Bazarbachi,Yves Lepelletier,Danielle Canioni,Thomas A. Waldmann,Olivier Hermine,Christophe Nicot

View Articletitled, Persistent inhibition of telomerase reprograms adult T-cell leukemia to p53-dependent senescence

The Flt3 receptor tyrosine kinase collaborates with NUP98-HOX fusions in acute myeloid leukemia

Lars Palmqvist,Bob Argiropoulos,Nicolas Pineault,Carolina Abramovich,Laura M. Sly,Gerald Krystal,Adrian Wan,R. Keith Humphries

View Articletitled, The Flt3 receptor tyrosine kinase collaborates with NUP98-HOX fusions in acute myeloid leukemia

Diagnostic application of flow cytometric characteristics of CD34⁺ cells in low-grade myelodysplastic syndromes

Kiyoyuki Ogata,Yoshifumi Kishikawa,Chikako Satoh,Hideto Tamura,Kazuo Dan,Akio Hayashi

View Articletitled, Diagnostic application of flow cytometric characteristics of CD34+ cells in low-grade myelodysplastic syndromes

Supplemental data

Glucocorticoid-induced glucocorticoid-receptor expression and promoter usage is not linked to glucocorticoid resistance in childhood ALL

Wim J. E. Tissing,Jules P. P. Meijerink,Bas Brinkhof,Mathilde J. C. Broekhuis,Renee X. Menezes,Monique L. den Boer,Rob Pieters

View Articletitled, Glucocorticoid-induced glucocorticoid-receptor expression and promoter usage is not linked to glucocorticoid resistance in childhood ALL

Genes contributing to minimal residual disease in childhood acute lymphoblastic leukemia: prognostic significance of CASP8AP2
Clinical Trials & Observations

Christian Flotho,Elaine Coustan-Smith,Deqing Pei,Shotaro Iwamoto,Guangchun Song,Cheng Cheng,Ching-Hon Pui,James R. Downing,Dario Campana

View Articletitled, Genes contributing to minimal residual disease in childhood acute lymphoblastic leukemia: prognostic significance of CASP8AP2

STAT3 induces transcription of the DNA methyltransferase 1 gene (DNMT1) in malignant T lymphocytes

Qian Zhang,Hong Y. Wang,Anders Woetmann,Puthiyaveettil N. Raghunath,Niels Odum,Mariusz A. Wasik

View Articletitled, STAT3 induces transcription of the DNA methyltransferase 1 gene (DNMT1) in malignant T lymphocytes

Rapamycin inhibits growth and survival of D816V-mutated c-kit mast cells

Marion Gabillot-Carré,Yves Lepelletier,Martine Humbert,Paulo de Sepuvelda,Nadine Ben Hamouda,Jean Pierre Zappulla,Roland Liblau,Antoine Ribadeau-Dumas,François Machavoine,Sébastien Letard,Cédric Baude,Aurélie Hermant,Ying Yang,Jacques Vargaftig,Christine Bodemer,Emmanuel Morelon,Olivier Lortholary,Christian Recher,Guy Laurent,Michel Dy,Michel Arock,Patrice Dubreuil,Olivier Hermine

View Articletitled, Rapamycin inhibits growth and survival of D816V-mutated c-kit mast cells

RED CELLS

The effect of fetal hemoglobin on the survival characteristics of sickle cells

Robert S. Franco,Zahida Yasin,Mary B. Palascak,Peter Ciraolo,Clinton H. Joiner,Donald L. Rucknagel

View Articletitled, The effect of fetal hemoglobin on the survival characteristics of sickle cells

cMYB is involved in the regulation of fetal hemoglobin production in adults

Jie Jiang,Steve Best,Stephan Menzel,Nicholas Silver,Mei I. Lai,Gabriela L. Surdulescu,Tim D. Spector,Swee Lay Thein

View Articletitled, cMYB is involved in the regulation of fetal hemoglobin production in adults

Supplemental data

STEM CELLS IN HEMATOLOGY

Human short-term repopulating cells have enhanced telomerase reverse transcriptase expression

Marcus Järås,Anna Edqvist,Johan Rebetz,Leif G. Salford,Bengt Widegren,Xiaolong Fan

View Articletitled, Human short-term repopulating cells have enhanced telomerase reverse transcriptase expression

TRANSPLANTATION

Long-term survival in refractory acute myeloid leukemia after sequential treatment with chemotherapy and reduced-intensity conditioning for allogeneic stem cell transplantation

Christoph Schmid,Michael Schleuning,Rainer Schwerdtfeger,Bernd Hertenstein,Eva Mischak-Weissinger,Donald Bunjes,Stephanie v. Harsdorf,Christoph Scheid,Udo Holtick,Hildegard Greinix,Felix Keil,Barbara Schneider,Michael Sandherr,Gesine Bug,Johanna Tischer,Georg Ledderose,Michael Hallek,Wolfgang Hiddemann,Hans-Jochem Kolb

View Articletitled, Long-term survival in refractory acute myeloid leukemia after sequential treatment with chemotherapy and reduced-intensity conditioning for allogeneic stem cell transplantation

Spermatogenesis in long-term survivors after allogeneic hematopoietic stem cell transplantation is associated with age, time interval since transplantation, and apparently absence of chronic GvHD
Clinical Trials & Observations

Alicia Rovó,André Tichelli,Jakob R. Passweg,Dominik Heim,Sandrine Meyer-Monard,Wolfgang Holzgreve,Alois Gratwohl,Christian De Geyter

View Articletitled, Spermatogenesis in long-term survivors after allogeneic hematopoietic stem cell transplantation is associated with age, time interval since transplantation, and apparently absence of chronic GvHD

CORRESPONDENCE

Selected anti-Epo receptor antibodies predict Epo receptor expression

Frédèrique Verdier,Sophie Gomez,Catherine Lacombe,Patrick Mayeux

View Articletitled, Selected anti-Epo receptor antibodies predict Epo receptor expression

Erythropoietin receptors on cancer cells: exciting perspectives, difficult to appreciate

Michael Henke,Ajay Verma,Geza Acs

View Articletitled, Erythropoietin receptors on cancer cells: exciting perspectives, difficult to appreciate

A chromosomal translocation in cyclin D1–negative/cyclin D2–positive mantle cell lymphoma fuses the CCND2 gene to the IGK locus

Stefan Gesk,Wolfram Klapper,José I. Martín-Subero,Inga Nagel,Lana Harder,Kai Fu,Heinz-Wolfram Bernd,Dennis D. Weisenburger,Reza Parwaresch,Reiner Siebert

View Articletitled, A chromosomal translocation in cyclin D1–negative/cyclin D2–positive mantle cell lymphoma fuses the CCND2 gene to the IGK locus

Phenotype of neoplastic cells in angioimmunoblastic T-cell lymphoma is consistent with activated follicular B helper T cells

Laszlo Krenacs,Patrick Schaerli,Gyongyi Kis,Eniko Bagdi

View Articletitled, Phenotype of neoplastic cells in angioimmunoblastic T-cell lymphoma is consistent with activated follicular B helper T cells

Immune thrombocytopenic purpura does not exhibit a disparity in prevalence between African American and white veterans

Ola Landgren,Gloria Gridley,Thomas R. Fears,Neil Caporaso

View Articletitled, Immune thrombocytopenic purpura does not exhibit a disparity in prevalence between African American and white veterans

Severe pulmonary complication after bortezomib treatment for multiple myeloma

James E. Boyer,Reema B. Batra,Joao L. Ascensao,Geraldine P. Schechter

View Articletitled, Severe pulmonary complication after bortezomib treatment for multiple myeloma

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Refined ELN 2024 risk stratification improves survival prognostication following venetoclax-based therapy in AML

Safety and efficacy of pegcetacoplan treatment for cold agglutinin disease and warm antibody autoimmune hemolytic anemia

Childhood Langerhans cell histiocytosis hematological involvement: severity associated with BRAFV600E loads

Long-term Outcomes of tyrosine kinase inhibitors in chronic myeloid leukemia

Leukemic myeloblasts with erythrophagocytosis

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Issue Archive

Table of Contents

INSIDE BLOOD

RIC for MDS: the glass is half full Clinical Trials & Observations

BLOOD WORK

PLENARY PAPERS

PERSPECTIVES

REVIEW ARTICLES

CHEMOKINES, CYTOKINES, AND INTERLEUKINS

CLINICAL TRIALS AND OBSERVATIONS

Superior effects of high-dose enzyme replacement therapy in type 1 Gaucher disease on bone marrow involvement and chitotriosidase levels: a 2-center retrospective analysis Clinical Trials & Observations

Retrospective comparison of reduced-intensity conditioning and conventional high-dose conditioning for allogeneic hematopoietic stem cell transplantation using HLA-identical sibling donors in myelodysplastic syndromes Clinical Trials & Observations

Stroke Prevention Trial in Sickle Cell Anemia (STOP): extended follow-up and final results Clinical Trials & Observations

Clinical significance of ZAP-70 protein expression in B-cell chronic lymphocytic leukemia Clinical Trials & Observations

GENE THERAPY

HEMATOPOIESIS

Identification of the nonreceptor tyrosine kinase MATK/CHK as an essential regulator of immune cells using Matk/CHK-deficient mice Brief Report

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Relative efficacy of intravenous immunoglobulin G in ameliorating thrombocytopenia induced by antiplatelet GPIIbIIIa versus GPIbα antibodies Brief Report

IMMUNOBIOLOGY

Proprotein convertase furin is preferentially expressed in T helper 1 cells and regulates interferon gamma Brief Report

NEOPLASIA

Plasma thrombopoietin compared with immunoglobulin heavy-chain mutation status as a predictor of survival in chronic lymphocytic leukemia Clinical Trials & Observations

Genes contributing to minimal residual disease in childhood acute lymphoblastic leukemia: prognostic significance of CASP8AP2 Clinical Trials & Observations

RED CELLS

STEM CELLS IN HEMATOLOGY

TRANSPLANTATION

Spermatogenesis in long-term survivors after allogeneic hematopoietic stem cell transplantation is associated with age, time interval since transplantation, and apparently absence of chronic GvHD Clinical Trials & Observations

CORRESPONDENCE

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RIC for MDS: the glass is half full
Clinical Trials & Observations

Superior effects of high-dose enzyme replacement therapy in type 1 Gaucher disease on bone marrow involvement and chitotriosidase levels: a 2-center retrospective analysis
Clinical Trials & Observations

Retrospective comparison of reduced-intensity conditioning and conventional high-dose conditioning for allogeneic hematopoietic stem cell transplantation using HLA-identical sibling donors in myelodysplastic syndromes
Clinical Trials & Observations

Stroke Prevention Trial in Sickle Cell Anemia (STOP): extended follow-up and final results
Clinical Trials & Observations

Clinical significance of ZAP-70 protein expression in B-cell chronic lymphocytic leukemia
Clinical Trials & Observations

Identification of the nonreceptor tyrosine kinase MATK/CHK as an essential regulator of immune cells using Matk/CHK-deficient mice
Brief Report

Relative efficacy of intravenous immunoglobulin G in ameliorating thrombocytopenia induced by antiplatelet GPIIbIIIa versus GPIbα antibodies
Brief Report

Proprotein convertase furin is preferentially expressed in T helper 1 cells and regulates interferon gamma
Brief Report

Plasma thrombopoietin compared with immunoglobulin heavy-chain mutation status as a predictor of survival in chronic lymphocytic leukemia
Clinical Trials & Observations

Genes contributing to minimal residual disease in childhood acute lymphoblastic leukemia: prognostic significance of CASP8AP2
Clinical Trials & Observations

Spermatogenesis in long-term survivors after allogeneic hematopoietic stem cell transplantation is associated with age, time interval since transplantation, and apparently absence of chronic GvHD
Clinical Trials & Observations