Skip Nav Destination

Issue Archive

Select Decade

Select Year

Issue

Volume 107, Issue 7

April 1 2006

In this Issue

INSIDE BLOOD
BLOOD WORK
PLENARY PAPERS
REVIEW IN TRANSLATIONAL HEMATOLOGY
ERRATA
CHEMOKINES, CYTOKINES, AND INTERLEUKINS
CLINICAL TRIALS AND OBSERVATIONS
GENE THERAPY
HEMATOPOIESIS
HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY
IMMUNOBIOLOGY
NEOPLASIA
PHAGOCYTES
RED CELLS
STEM CELLS IN HEMATOLOGY
TRANSFUSION MEDICINE
TRANSPLANTATION
CORRESPONDENCE

INSIDE BLOOD

IMMUNOBIOLOGY

IL-7 comes of age

Terry J. Fry

View Articletitled, IL-7 comes of age

CLINICAL TRIALS AND OBSERVATIONS

ATO: the forefront of APL treatment?
Clinical Trials & Observations

Dan Douer

View Articletitled, ATO: the forefront of APL treatment?

TRANSPLANTATION

Of mice and men

Judith A. Shizuru

View Articletitled, Of mice and men

CLINICAL OBSERVATIONS

Putting the “Tux” on ITP

Douglas B. Cines

View Articletitled, Putting the “Tux” on ITP

IMMUNOBIOLOGY

Tolerogenic dendritic cells: a KARAP/DAP12–IRF-8/ICSBP balance

Eric Vivier,Marc Dalod

View Articletitled, Tolerogenic dendritic cells: a KARAP/DAP12–IRF-8/ICSBP balance

NEOPLASIA

Host EBV communication

David A. Thorley-Lawson

View Articletitled, Host EBV communication

GENE THERAPY

FIXing hemophilia B with gene therapy

John A. Chiorini

View Articletitled, FIXing hemophilia B with gene therapy

NEOPLASIA

A novel gene for an old disease

Federico Caligaris-Cappio

View Articletitled, A novel gene for an old disease

RED CELLS

Treating iron overload with hepcidin

Clara Camaschella

View Articletitled, Treating iron overload with hepcidin

RED CELLS

Does eNOS stand for erythrocytic NO synthase?

Mark T. Gladwin

View Articletitled, Does eNOS stand for erythrocytic NO synthase?

BLOOD WORK

Precursor B-cell lymphoblastic leukemia

View Articletitled, Precursor B-cell lymphoblastic leukemia

PLENARY PAPERS

Role of melanotransferrin in iron metabolism: studies using targeted gene disruption in vivo
Brief Report

Eric O. Sekyere,Louise L. Dunn,Yohan Suryo Rahmanto,Des R. Richardson

View Articletitled, Role of melanotransferrin in iron metabolism: studies using targeted gene disruption in vivo

Lack of allosterically controlled intramolecular transfer of nitric oxide from the heme to cysteine in the β subunit of hemoglobin
Brief Report

Kris T. Huang,Ivan Azarov,Swati Basu,Jinming Huang,Daniel B. Kim-Shapiro

View Articletitled, Lack of allosterically controlled intramolecular transfer of nitric oxide from the heme to cysteine in the β subunit of hemoglobin

REVIEW IN TRANSLATIONAL HEMATOLOGY

Scientific and clinical opportunities for modeling blood disorders with embryonic stem cells

M. William Lensch,George Q. Daley

View Articletitled, Scientific and clinical opportunities for modeling blood disorders with embryonic stem cells

ERRATA

Erratum for vol. 107, p. 1996

View Articletitled, Erratum for vol. 107, p. 1996

CHEMOKINES, CYTOKINES, AND INTERLEUKINS

Upon viral exposure, myeloid and plasmacytoid dendritic cells produce 3 waves of distinct chemokines to recruit immune effectors

Bernard Piqueras,John Connolly,Heidi Freitas,Anna Karolina Palucka,Jacques Banchereau

View Articletitled, Upon viral exposure, myeloid and plasmacytoid dendritic cells produce 3 waves of distinct chemokines to recruit immune effectors

Supplemental data

CLINICAL TRIALS AND OBSERVATIONS

Intravascular survival of red cells coated with a mutated human anti-D antibody engineered to lack destructive activity
Clinical Trials & Observations

Kathryn L. Armour,David R. Parry-Jones,Nigel Beharry,James R. Ballinger,Rosey Mushens,R. Keith Williams,Cynthia Beatty,Simon Stanworth,Paul Lloyd-Evans,Marion Scott,Michael R. Clark,A. Michael Peters,Lorna M. Williamson

View Articletitled, Intravascular survival of red cells coated with a mutated human anti-D antibody engineered to lack destructive activity

Single-agent arsenic trioxide in the treatment of newly diagnosed acute promyelocytic leukemia: durable remissions with minimal toxicity
Clinical Trials & Observations

Vikram Mathews,Biju George,Kavitha M. Lakshmi,Auro Viswabandya,Ashish Bajel,Poonkuzhali Balasubramanian,Ramachandran Velayudhan Shaji,Vivi M. Srivastava,Alok Srivastava,Mammen Chandy

View Articletitled, Single-agent arsenic trioxide in the treatment of newly diagnosed acute promyelocytic leukemia: durable remissions with minimal toxicity

Total therapy 2 without thalidomide in comparison with total therapy 1: role of intensified induction and posttransplantation consolidation therapies
Clinical Trials & Observations

Bart Barlogie,Guido Tricot,Erik Rasmussen,Elias Anaissie,Frits van Rhee,Maurizio Zangari,Athanasios Fassas,Klaus Hollmig,Mauricio Pineda-Roman,John Shaughnessy,Joshua Epstein,John Crowley

View Articletitled, Total therapy 2 without thalidomide in comparison with total therapy 1: role of intensified induction and posttransplantation consolidation therapies

Prospective phase 1/2 study of rituximab in childhood and adolescent chronic immune thrombocytopenic purpura
Clinical Trials & Observations Brief Report

Carolyn M. Bennett,Zora R. Rogers,Daniel D. Kinnamon,James B. Bussel,Donald H. Mahoney,Thomas C. Abshire,Hadi Sawaf,Theodore B. Moore,Mignon L. Loh,Bertil E. Glader,Maggie C. McCarthy,Brigitta U. Mueller,Thomas A. Olson,Adonis N. Lorenzana,William C. Mentzer,George R. Buchanan,Henry A. Feldman,Ellis J. Neufeld,the Pediatric Rituximab/ITP Study Group and the Glaser Pediatric Research Network

View Articletitled, Prospective phase 1/2 study of rituximab in childhood and adolescent chronic immune thrombocytopenic purpura

Supplemental data

GENE THERAPY

Differentiation of naive cord-blood T cells into CD19-specific cytolytic effectors for posttransplantation adoptive immunotherapy

Lisa Marie Serrano,Timothy Pfeiffer,Simon Olivares,Tontanai Numbenjapon,Jennifer Bennitt,Daniel Kim,David Smith,George McNamara,Zaid Al-Kadhimi,Joseph Rosenthal,Stephen J. Forman,Michael C. Jensen,Laurence J. N. Cooper

View Articletitled, Differentiation of naive cord-blood T cells into CD19-specific cytolytic effectors for posttransplantation adoptive immunotherapy

Supplemental data

Self-complementary adeno-associated virus vectors containing a novel liver-specific human factor IX expression cassette enable highly efficient transduction of murine and nonhuman primate liver

Amit C. Nathwani,John T. Gray,Catherine Y. C. Ng,Junfang Zhou,Yunyu Spence,Simon N. Waddington,Edward G. D. Tuddenham,Geoffrey Kemball-Cook,Jenny McIntosh,Mariette Boon-Spijker,Koen Mertens,Andrew M. Davidoff

View Articletitled, Self-complementary adeno-associated virus vectors containing a novel liver-specific human factor IX expression cassette enable highly efficient transduction of murine and nonhuman primate liver

Supplemental data

HEMATOPOIESIS

Core erythropoietin receptor signals for late erythroblast development

Madhu P. Menon,Jing Fang,Don M. Wojchowski

View Articletitled, Core erythropoietin receptor signals for late erythroblast development

Supplemental data

Expression of rearranged TCRγ genes in natural killer cells suggests a minor thymus-dependent pathway of lineage commitment

Linnea Lora Veinotte,Chelsea Pamela Greenwood,Nastaran Mohammadi,Christine Anna Parachoniak,Fumio Takei

View Articletitled, Expression of rearranged TCRγ genes in natural killer cells suggests a minor thymus-dependent pathway of lineage commitment

Supplemental data

Mutations in dyskeratosis congenita: their impact on telomere length and the diversity of clinical presentation
Clinical Trials & Observations

Tom J. Vulliamy,Anna Marrone,Stuart W. Knight,Amanda Walne,Philip J. Mason,Inderjeet Dokal

View Articletitled, Mutations in dyskeratosis congenita: their impact on telomere length and the diversity of clinical presentation

Id helix-loop-helix proteins negatively regulate TRANCE-mediated osteoclast differentiation

Junwon Lee,Kabsun Kim,Jung Ha Kim,Hye Mi Jin,Han Kyung Choi,Seoung-Hoon Lee,Hyun Kook,Kyung Keun Kim,Yoshifumi Yokota,Soo Young Lee,Yongwon Choi,Nacksung Kim

View Articletitled, Id helix-loop-helix proteins negatively regulate TRANCE-mediated osteoclast differentiation

The Notch ligand delta-1 is a hematopoietic development cofactor for plasmacytoid dendritic cells

Aurélie Olivier,Evelyne Lauret,Patrick Gonin,Anne Galy

View Articletitled, The Notch ligand delta-1 is a hematopoietic development cofactor for plasmacytoid dendritic cells

Supplemental data

Hepcidin inhibits in vitro erythroid colony formation at reduced erythropoietin concentrations
Brief Report

Gail Dallalio,Erin Law,Robert T. Means, Jr

View Articletitled, Hepcidin inhibits in vitro erythroid colony formation at reduced erythropoietin concentrations

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Hypoxic induction of an HIF-1α–dependent bFGF autocrine loop drives angiogenesis in human endothelial cells

Maura Calvani,Annamaria Rapisarda,Badarch Uranchimeg,Robert H. Shoemaker,Giovanni Melillo

View Articletitled, Hypoxic induction of an HIF-1α–dependent bFGF autocrine loop drives angiogenesis in human endothelial cells

αIIbβ3 biogenesis is controlled by engagement of αIIb in the calnexin cycle via the N15-linked glycan

W. Beau Mitchell,JiHong Li,Deborah L. French,Barry S. Coller

View Articletitled, αIIbβ3 biogenesis is controlled by engagement of αIIb in the calnexin cycle via the N15-linked glycan

The extracellular adherence protein (Eap) of Staphylococcus aureus inhibits wound healing by interfering with host defense and repair mechanisms

Athanasios N. Athanasopoulos,Matina Economopoulou,Valeria V. Orlova,Astrid Sobke,Darius Schneider,Holger Weber,Hellmut G. Augustin,Sabine A. Eming,Uwe Schubert,Thomas Linn,Peter P. Nawroth,Muzaffar Hussain,Hans-Peter Hammes,Mathias Herrmann,Klaus T. Preissner,Triantafyllos Chavakis

View Articletitled, The extracellular adherence protein (Eap) of Staphylococcus aureus inhibits wound healing by interfering with host defense and repair mechanisms

The small GTPase Rap1b regulates the cross talk between platelet integrin α₂β₁ and integrin α_IIbβ₃

Bruno Bernardi,Gianni F. Guidetti,Francesca Campus,Jill R. Crittenden,Ann M. Graybiel,Cesare Balduini,Mauro Torti

View Articletitled, The small GTPase Rap1b regulates the cross talk between platelet integrin α2β1 and integrin αIIbβ3

Differential regulation of endothelial exocytosis of P-selectin and von Willebrand factor by protease-activated receptors and cAMP

John H. Cleator,Wen Qin Zhu,Douglas E. Vaughan,Heidi E. Hamm

View Articletitled, Differential regulation of endothelial exocytosis of P-selectin and von Willebrand factor by protease-activated receptors and cAMP

Variable phosphorylation states of pigment-epithelium–derived factor differentially regulate its function

Galia Maik-Rachline,Rony Seger

View Articletitled, Variable phosphorylation states of pigment-epithelium–derived factor differentially regulate its function

Placental dermatan sulfate: isolation, anticoagulant activity, and association with heparin cofactor II

Tusar K. Giri,Douglas M. Tollefsen

View Articletitled, Placental dermatan sulfate: isolation, anticoagulant activity, and association with heparin cofactor II

Lack of F8 mRNA: a novel mechanism leading to hemophilia A

Osman El-Maarri,Heike Singer,Claudia Klein,Matthias Watzka,Ursula Herbiniaux,Hans H. Brackmann,Jörg Schröder,Jochen Graw,Clemens R. Müller,Wolfgang Schramm,Rainer Schwaab,Thomas Haaf,Peter Hanfland,Johannes Oldenburg

View Articletitled, Lack of F8 mRNA: a novel mechanism leading to hemophilia A

Supplemental data

Thrombophilic abnormalities, oral contraceptives, and risk of cerebral vein thrombosis: a meta-analysis
Clinical Trials & Observations

Francesco Dentali,Mark Crowther,Walter Ageno

View Articletitled, Thrombophilic abnormalities, oral contraceptives, and risk of cerebral vein thrombosis: a meta-analysis

Evidence for incorporation of bone marrow–derived endothelial cells into perfused blood vessels in tumors
Brief Report

Dan G. Duda,Kenneth S. Cohen,Sergey V. Kozin,Jean Y. Perentes,Dai Fukumura,David T. Scadden,Rakesh K. Jain

View Articletitled, Evidence for incorporation of bone marrow–derived endothelial cells into perfused blood vessels in tumors

Supplemental data

IMMUNOBIOLOGY

A transforming growth factor–β–induced protein stimulates endocytosis and is up-regulated in immature dendritic cells

Weiping Cao,Patrick Tan,Chee How Lee,Haifeng Zhang,Jinhua Lu

View Articletitled, A transforming growth factor–β–induced protein stimulates endocytosis and is up-regulated in immature dendritic cells

Supplemental data

CD40-activated B cells express full lymph node homing triad and induce T-cell chemotaxis: potential as cellular adjuvants

Michael von Bergwelt-Baildon,Alexander Shimabukuro-Vornhagen,Alexey Popov,Nela Klein-Gonzalez,Francesca Fiore,Svenja Debey,Andreas Draube,Britta Maecker,Isaura Menezes,Lee M. Nadler,Joachim L. Schultze

View Articletitled, CD40-activated B cells express full lymph node homing triad and induce T-cell chemotaxis: potential as cellular adjuvants

Supplemental data

Posttranscriptional regulation of Fas (CD95) ligand killing activity by lipid rafts

Ueli Nachbur,Daniela Kassahn,Shida Yousefi,Daniel F. Legler,Thomas Brunner

View Articletitled, Posttranscriptional regulation of Fas (CD95) ligand killing activity by lipid rafts

T-bet concomitantly controls migration, survival, and effector functions during the development of Vα14i NKT cells

Jennifer L. Matsuda,Qianjun Zhang,Rachel Ndonye,Stewart K. Richardson,Amy R. Howell,Laurent Gapin

View Articletitled, T-bet concomitantly controls migration, survival, and effector functions during the development of Vα14i NKT cells

Supplemental data

Vaccination of human subjects expands both specific and bystander memory T cells but antibody production remains vaccine specific

Gianfranco Di Genova,Joanna Roddick,Feargal McNicholl,Freda K. Stevenson

View Articletitled, Vaccination of human subjects expands both specific and bystander memory T cells but antibody production remains vaccine specific

Supplemental data

De novo synthesis of early growth response factor-1 is required for the full responsiveness of mast cells to produce TNF and IL-13 by IgE and antigen stimulation

Bo Li,Melanie R. Power,Tong-Jun Lin

View Articletitled, De novo synthesis of early growth response factor-1 is required for the full responsiveness of mast cells to produce TNF and IL-13 by IgE and antigen stimulation

SLAM/SLAM interactions inhibit CD40-induced production of inflammatory cytokines in monocyte-derived dendritic cells

Bence Réthi,Péter Gogolák,Istvan Szatmari,Ágota Veres,Erika Erdôs,Laszlo Nagy,Éva Rajnavölgyi,Cox Terhorst,Árpád Lányi

View Articletitled, SLAM/SLAM interactions inhibit CD40-induced production of inflammatory cytokines in monocyte-derived dendritic cells

Persistence of naive CD45RA⁺ regulatory T cells in adult life

Nabila Seddiki,Brigitte Santner-Nanan,Stuart G. Tangye,Stephen I. Alexander,Michael Solomon,Soon Lee,Ralph Nanan,Barbara Fazekas de Saint Groth

View Articletitled, Persistence of naive CD45RA+ regulatory T cells in adult life

Identifying a common molecular mechanism for inhibition of MITF and STAT3 by PIAS3

Carmit Levy,Yu-Nee Lee,Hovav Nechushtan,Ora Schueler-Furman,Amir Sonnenblick,Shelley Hacohen,Ehud Razin

View Articletitled, Identifying a common molecular mechanism for inhibition of MITF and STAT3 by PIAS3

Toward the identification of a tolerogenic signature in IDO-competent dendritic cells

Ciriana Orabona,Paolo Puccetti,Carmine Vacca,Silvio Bicciato,Alessandra Luchini,Francesca Fallarino,Roberta Bianchi,Enrico Velardi,Katia Perruccio,Andrea Velardi,Vincenzo Bronte,Maria Cristina Fioretti,Ursula Grohmann

View Articletitled, Toward the identification of a tolerogenic signature in IDO-competent dendritic cells

Supplemental data

Altered IL-7Rα expression with aging and the potential implications of IL-7 therapy on CD8⁺ T-cell immune responses
Clinical Trials & Observations

Hang-Rae Kim,Myung Sun Hong,Jin Myung Dan,Insoo Kang

View Articletitled, Altered IL-7Rα expression with aging and the potential implications of IL-7 therapy on CD8+ T-cell immune responses

CD7-restricted activation of Fas-mediated apoptosis: a novel therapeutic approach for acute T-cell leukemia

Edwin Bremer,Bram ten Cate,Douwe F. Samplonius,Lou F. M. H. de Leij,Wijnand Helfrich

View Articletitled, CD7-restricted activation of Fas-mediated apoptosis: a novel therapeutic approach for acute T-cell leukemia

In vivo disruption of tolerogenic cross-presentation mechanisms uncovers an effective T-cell activation by B-cell lymphomas leading to antitumor immunity

Pedro Horna,Alex Cuenca,Fengdong Cheng,Jason Brayer,Hong-Wei Wang,Ivan Borrello,Hyam Levitsky,Eduardo M. Sotomayor

View Articletitled, In vivo disruption of tolerogenic cross-presentation mechanisms uncovers an effective T-cell activation by B-cell lymphomas leading to antitumor immunity

Overexpression of HES-1 is not sufficient to impose T-cell differentiation on human hematopoietic stem cells
Brief Report

Inge Hoebeke,Magda De Smedt,Inge Van de Walle,Katia Reynvoet,Greet De Smet,Jean Plum,Georges Leclercq

View Articletitled, Overexpression of HES-1 is not sufficient to impose T-cell differentiation on human hematopoietic stem cells

NEOPLASIA

B-lymphocyte stimulator (BLyS) stimulates immunoglobulin production and malignant B-cell growth in Waldenström macroglobulinemia

Sherine F. Elsawa,Anne J. Novak,Deanna M. Grote,Steven C. Ziesmer,Thomas E. Witzig,Robert A. Kyle,Stacey R. Dillon,Brandon Harder,Jane A. Gross,Stephen M. Ansell

View Articletitled, B-lymphocyte stimulator (BLyS) stimulates immunoglobulin production and malignant B-cell growth in Waldenström macroglobulinemia

Strikingly homologous immunoglobulin gene rearrangements and poor outcome in V_H3-21-using chronic lymphocytic leukemia patients independent of geographic origin and mutational status
Clinical Trials & Observations

Mia Thorsélius,Alexander Kröber,Fiona Murray,Ulf Thunberg,Gerard Tobin,Andreas Bühler,Dirk Kienle,Emilia Albesiano,Rossana Maffei,Lan-Phuong Dao-Ung,James Wiley,Juhani Vilpo,Anna Laurell,Mats Merup,Göran Roos,Karin Karlsson,Nicholas Chiorazzi,Roberto Marasca,Hartmut Döhner,Stephan Stilgenbauer,Richard Rosenquist

View Articletitled, Strikingly homologous immunoglobulin gene rearrangements and poor outcome in VH3-21-using chronic lymphocytic leukemia patients independent of geographic origin and mutational status

Supplemental data

Apoptosis and complement-mediated lysis of myeloma cells by polyclonal rabbit antithymocyte globulin

Martin S. Zand,Thuong Vo,Tina Pellegrin,Raymond Felgar,Jane L. Liesveld,Jainulabdeen J. Ifthikharuddin,Camille N. Abboud,Ignacio Sanz,Jennifer Huggins

View Articletitled, Apoptosis and complement-mediated lysis of myeloma cells by polyclonal rabbit antithymocyte globulin

Identification of a gene on chromosome 12q22 uniquely overexpressed in chronic lymphocytic leukemia

Anne Mette Buhl,Jesper Jurlander,Flemming S. Jørgensen,Anne Marie Ottesen,Jack B. Cowland,Lise Mette Gjerdrum,Brian V. Hansen,Henrik Leffers

View Articletitled, Identification of a gene on chromosome 12q22 uniquely overexpressed in chronic lymphocytic leukemia

Supplemental data

Long-term risk of cardiovascular disease after treatment for aggressive non-Hodgkin lymphoma
Clinical Trials & Observations

Elizabeth C. Moser,Evert M. Noordijk,Flora E. van Leeuwen,Saskia le Cessie,Joke W. Baars,José Thomas,Patrice Carde,Jacobus H. Meerwaldt,Martine van Glabbeke,Hanneke C. Kluin-Nelemans

View Articletitled, Long-term risk of cardiovascular disease after treatment for aggressive non-Hodgkin lymphoma

Impaired class switch recombination (CSR) in Waldenström macroglobulinemia (WM) despite apparently normal CSR machinery

Jitra Kriangkum,Brian J. Taylor,Erin Strachan,Michael J. Mant,Tony Reiman,Andrew R. Belch,Linda M. Pilarski

View Articletitled, Impaired class switch recombination (CSR) in Waldenström macroglobulinemia (WM) despite apparently normal CSR machinery

IL-10 can induce the expression of EBV-encoded latent membrane protein-1 (LMP-1) in the absence of EBNA-2 in B lymphocytes and in Burkitt lymphoma- and NK lymphoma-derived cell lines

Lorand L. Kis,Miki Takahara,Noemi Nagy,George Klein,Eva Klein

View Articletitled, IL-10 can induce the expression of EBV-encoded latent membrane protein-1 (LMP-1) in the absence of EBNA-2 in B lymphocytes and in Burkitt lymphoma- and NK lymphoma-derived cell lines

PHAGOCYTES

Human neutrophil peptides induce interleukin-8 production through the P2Y₆ signaling pathway

Aye Aye Khine,Lorenzo Del Sorbo,Rosanna Vaschetto,Stefanos Voglis,Elizabeth Tullis,Arthur S. Slutsky,Gregory P. Downey,Haibo Zhang

View Articletitled, Human neutrophil peptides induce interleukin-8 production through the P2Y6 signaling pathway

RED CELLS

Red blood cells express a functional endothelial nitric oxide synthase

Petra Kleinbongard,Rainer Schulz,Tienush Rassaf,Thomas Lauer,André Dejam,Thomas Jax,Intan Kumara,Putrika Gharini,Svetlana Kabanova,Burcin Özüyaman,Hans-Georg Schnürch,Axel Gödecke,Artur-A. Weber,Mirko Robenek,Horst Robenek,Wilhelm Bloch,Peter Rösen,Malte Kelm

View Articletitled, Red blood cells express a functional endothelial nitric oxide synthase

Chronic hepcidin induction causes hyposideremia and alters the pattern of cellular iron accumulation in hemochromatotic mice

Lydie Viatte,Gaël Nicolas,Dan-Qing Lou,Myriam Bennoun,Jeanne-Claire Lesbordes-Brion,François Canonne-Hergaux,Kai Schönig,Hermann Bujard,Axel Kahn,Nancy C. Andrews,Sophie Vaulont

View Articletitled, Chronic hepcidin induction causes hyposideremia and alters the pattern of cellular iron accumulation in hemochromatotic mice

STEM CELLS IN HEMATOLOGY

Lack of α4 integrin expression in stem cells restricts competitive function and self-renewal activity

Gregory V. Priestley,Linda M. Scott,Tatiana Ulyanova,Thalia Papayannopoulou

View Articletitled, Lack of α4 integrin expression in stem cells restricts competitive function and self-renewal activity

Enhanced engraftment of hematopoietic stem/progenitor cells by the transient inhibition of an adaptor protein, Lnk

Hitoshi Takizawa,Chiyomi Kubo-Akashi,Ikuo Nobuhisa,Sang-Mo Kwon,Masanori Iseki,Tetsuya Taga,Kiyoshi Takatsu,Satoshi Takaki

View Articletitled, Enhanced engraftment of hematopoietic stem/progenitor cells by the transient inhibition of an adaptor protein, Lnk

TRANSFUSION MEDICINE

A novel murine model of fetal and neonatal alloimmune thrombocytopenia: response to intravenous IgG therapy

Heyu Ni,Pingguo Chen,Christopher M. Spring,Ebrahim Sayeh,John W. Semple,Alan H. Lazarus,Richard O. Hynes,John Freedman

View Articletitled, A novel murine model of fetal and neonatal alloimmune thrombocytopenia: response to intravenous IgG therapy

TRANSPLANTATION

Graft rejection after unrelated donor hematopoietic stem cell transplantation for thalassemia is associated with nonpermissive HLA-DPB1 disparity in host-versus-graft direction
Clinical Trials & Observations

Katharina Fleischhauer,Franco Locatelli,Marco Zecca,Maria Grazia Orofino,Claudio Giardini,Piero De Stefano,Andrea Pession,Angela Maria Iannone,Carlo Carcassi,Elisabetta Zino,Giorgio La Nasa

View Articletitled, Graft rejection after unrelated donor hematopoietic stem cell transplantation for thalassemia is associated with nonpermissive HLA-DPB1 disparity in host-versus-graft direction

Donor CD4⁺ T and B cells in transplants induce chronic graft-versus-host disease with autoimmune manifestations

Chunyan Zhang,Ivan Todorov,Zhifang Zhang,Yinping Liu,Fouad Kandeel,Stephen Forman,Samuel Strober,Defu Zeng

View Articletitled, Donor CD4+ T and B cells in transplants induce chronic graft-versus-host disease with autoimmune manifestations

Supplemental data

Oral valganciclovir leads to higher exposure to ganciclovir than intravenous ganciclovir in patients following allogeneic stem cell transplantation
Clinical Trials & Observations

Hermann Einsele,Pierre Reusser,Martin Bornhäuser,Peter Kalhs,Gerhard Ehninger,Holger Hebart,Yves Chalandon,Nicolaus Kröger,Bernd Hertenstein,Frank Rohde,for the EBMT Working Group on Infectious Disease

View Articletitled, Oral valganciclovir leads to higher exposure to ganciclovir than intravenous ganciclovir in patients following allogeneic stem cell transplantation

CORRESPONDENCE

Severe human herpesvirus-8 primary infection in a renal transplant patient successfully treated with anti-CD20 monoclonal antibody

Olivier Thaunat,Marie-France Mamzer-Bruneel,Felix Agbalika,Françoise Valensi,Marcia Venditto,Céleste Lebbe,Camille Frances,Romain Kania,Lucienne Chatenoud,Corinne Antoine,Srinivas Kaveri,Henri Kreis,Emmanuel Morelon

View Articletitled, Severe human herpesvirus-8 primary infection in a renal transplant patient successfully treated with anti-CD20 monoclonal antibody

Mutagenic potential of temozolomide in bone marrow cells in vivo

Hartmut Geiger,David Schleimer,Kalpana J. Nattamai,Stefanie R. Dannenmann,Stella M. Davies,Brian D. Weiss

View Articletitled, Mutagenic potential of temozolomide in bone marrow cells in vivo

Fibrinogen containing γ′ chains

David H. Farrell

View Articletitled, Fibrinogen containing γ′ chains

Elemental arsenic entered the cerebrospinal fluid during oral arsenic trioxide treatment of meningeal relapse of acute promyelocytic leukemia

Wing-Yan Au,Sidney Tam,Bonnie M. Fong,Yok-Lam Kwong

View Articletitled, Elemental arsenic entered the cerebrospinal fluid during oral arsenic trioxide treatment of meningeal relapse of acute promyelocytic leukemia

The infectious consequences of rituximab addition to fludarabine-containing regimens

Constantine S. Tam,John F. Seymour

View Articletitled, The infectious consequences of rituximab addition to fludarabine-containing regimens

The case for rituximab in AIDS-related lymphoma

Kieron Dunleavy,Wyndham H. Wilson

View Articletitled, The case for rituximab in AIDS-related lymphoma

Cover Image

Cover Image
Front Matter
Table of Contents
Advertising
Editorial Board

All Issues

Advertisement intended for health care professionals

Email alerts

First Edition Alert

Latest Issue Alert

Latest
Most Read
Most Cited

Two strikes, base hit: odronextamab after CAR T cells in LBCL

“When I’m 64”: functional shift of aging platelets

Introduction to a review series on acute lymphoblastic leukemia

Prizloncabtagene autoleucel: a new CAR T cell for B-NHL

Blood-Based Proteomic Profiling Identifies OSMR as a Novel Biomarker of AML Outcomes

Advertisement intended for health care professionals

Issue Archive

Table of Contents

INSIDE BLOOD

ATO: the forefront of APL treatment? Clinical Trials & Observations

BLOOD WORK

PLENARY PAPERS

Role of melanotransferrin in iron metabolism: studies using targeted gene disruption in vivo Brief Report

Lack of allosterically controlled intramolecular transfer of nitric oxide from the heme to cysteine in the β subunit of hemoglobin Brief Report

REVIEW IN TRANSLATIONAL HEMATOLOGY

ERRATA

CHEMOKINES, CYTOKINES, AND INTERLEUKINS

CLINICAL TRIALS AND OBSERVATIONS

Intravascular survival of red cells coated with a mutated human anti-D antibody engineered to lack destructive activity Clinical Trials & Observations

Single-agent arsenic trioxide in the treatment of newly diagnosed acute promyelocytic leukemia: durable remissions with minimal toxicity Clinical Trials & Observations

Total therapy 2 without thalidomide in comparison with total therapy 1: role of intensified induction and posttransplantation consolidation therapies Clinical Trials & Observations

Prospective phase 1/2 study of rituximab in childhood and adolescent chronic immune thrombocytopenic purpura Clinical Trials & Observations Brief Report

GENE THERAPY

HEMATOPOIESIS

Mutations in dyskeratosis congenita: their impact on telomere length and the diversity of clinical presentation Clinical Trials & Observations

Hepcidin inhibits in vitro erythroid colony formation at reduced erythropoietin concentrations Brief Report

HEMOSTASIS, THROMBOSIS, AND VASCULAR BIOLOGY

Thrombophilic abnormalities, oral contraceptives, and risk of cerebral vein thrombosis: a meta-analysis Clinical Trials & Observations

Evidence for incorporation of bone marrow–derived endothelial cells into perfused blood vessels in tumors Brief Report

IMMUNOBIOLOGY

Altered IL-7Rα expression with aging and the potential implications of IL-7 therapy on CD8+ T-cell immune responses Clinical Trials & Observations

Overexpression of HES-1 is not sufficient to impose T-cell differentiation on human hematopoietic stem cells Brief Report

NEOPLASIA

Strikingly homologous immunoglobulin gene rearrangements and poor outcome in VH3-21-using chronic lymphocytic leukemia patients independent of geographic origin and mutational status Clinical Trials & Observations

Long-term risk of cardiovascular disease after treatment for aggressive non-Hodgkin lymphoma Clinical Trials & Observations

PHAGOCYTES

RED CELLS

STEM CELLS IN HEMATOLOGY

TRANSFUSION MEDICINE

TRANSPLANTATION

Graft rejection after unrelated donor hematopoietic stem cell transplantation for thalassemia is associated with nonpermissive HLA-DPB1 disparity in host-versus-graft direction Clinical Trials & Observations

Oral valganciclovir leads to higher exposure to ganciclovir than intravenous ganciclovir in patients following allogeneic stem cell transplantation Clinical Trials & Observations

CORRESPONDENCE

Cover Image

Email alerts

ASH Publications

American Society of Hematology

This Feature Is Available To Subscribers Only

ATO: the forefront of APL treatment?
Clinical Trials & Observations

Role of melanotransferrin in iron metabolism: studies using targeted gene disruption in vivo
Brief Report

Lack of allosterically controlled intramolecular transfer of nitric oxide from the heme to cysteine in the β subunit of hemoglobin
Brief Report

Intravascular survival of red cells coated with a mutated human anti-D antibody engineered to lack destructive activity
Clinical Trials & Observations

Single-agent arsenic trioxide in the treatment of newly diagnosed acute promyelocytic leukemia: durable remissions with minimal toxicity
Clinical Trials & Observations

Total therapy 2 without thalidomide in comparison with total therapy 1: role of intensified induction and posttransplantation consolidation therapies
Clinical Trials & Observations

Prospective phase 1/2 study of rituximab in childhood and adolescent chronic immune thrombocytopenic purpura
Clinical Trials & Observations Brief Report

Mutations in dyskeratosis congenita: their impact on telomere length and the diversity of clinical presentation
Clinical Trials & Observations

Hepcidin inhibits in vitro erythroid colony formation at reduced erythropoietin concentrations
Brief Report

Thrombophilic abnormalities, oral contraceptives, and risk of cerebral vein thrombosis: a meta-analysis
Clinical Trials & Observations

Evidence for incorporation of bone marrow–derived endothelial cells into perfused blood vessels in tumors
Brief Report

Altered IL-7Rα expression with aging and the potential implications of IL-7 therapy on CD8⁺ T-cell immune responses
Clinical Trials & Observations

Overexpression of HES-1 is not sufficient to impose T-cell differentiation on human hematopoietic stem cells
Brief Report

Strikingly homologous immunoglobulin gene rearrangements and poor outcome in V_H3-21-using chronic lymphocytic leukemia patients independent of geographic origin and mutational status
Clinical Trials & Observations

Long-term risk of cardiovascular disease after treatment for aggressive non-Hodgkin lymphoma
Clinical Trials & Observations

Graft rejection after unrelated donor hematopoietic stem cell transplantation for thalassemia is associated with nonpermissive HLA-DPB1 disparity in host-versus-graft direction
Clinical Trials & Observations

Oral valganciclovir leads to higher exposure to ganciclovir than intravenous ganciclovir in patients following allogeneic stem cell transplantation
Clinical Trials & Observations