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Peter P. Nawroth
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Journal Articles

Signal integration at the PI3K-p85-XBP1 hub endows coagulation protease activated protein C with insulin-like function

Thati Madhusudhan, Hongjie Wang, Sanchita Ghosh, Wei Dong, Varun Kumar, Moh'd Mohanad Al-Dabet, Jayakumar Manoharan, Sumra Nazir, Ahmed Elwakiel, Fabian Bock, Shrey Kohli, Andi Marquardt, Ibrahim Sögüt, Khurrum Shahzad, Andreas J. Müller, Charles T. Esmon, Peter P. Nawroth, Jochen Reiser, Triantafyllos Chavakis, Wolfram Ruf, Berend Isermann
Journal: Blood
Blood (2017) 130 (12): 1445–1455.
https://doi.org/10.1182/blood-2017-02-767921
Published: 2017
Includes: Supplemental data
Journal Articles

Disulfide HMGB1 derived from platelets coordinates venous thrombosis in mice

Konstantin Stark, Vanessa Philippi, Sven Stockhausen, Johanna Busse, Antonella Antonelli, Meike Miller, Irene Schubert, Parandis Hoseinpour, Sue Chandraratne, Marie-Luise von Brühl, Florian Gaertner, Michael Lorenz, Alessandra Agresti, Raffaele Coletti, Daniel J. Antoine, Ralf Heermann, Kirsten Jung, Sven Reese, Iina Laitinen, Markus Schwaiger, Axel Walch, Markus Sperandio, Peter P. Nawroth, Christoph Reinhardt, Sven Jäckel, Marco E. Bianchi, Steffen Massberg
Journal: Blood
Blood (2016) 128 (20): 2435–2449.
https://doi.org/10.1182/blood-2016-04-710632
Published: 2016
Includes: Multimedia, Supplemental data
Journal Articles

Activated Protein C Targets PI3K-p85/XBP1 Pathway to Inhibit Hyperglycemia Induced Endoplasmic Reticulum Stress in Diabetic Nephropathy

Berend H. Isermann, MD, Hongjie Wang, MD, Peter P. Nawroth, MD, Thati Madhusudhan, PhD
Journal: Blood
Blood (2012) 120 (21): 3354.
https://doi.org/10.1182/blood.V120.21.3354.3354
Published: 2012
Journal Articles

Cytoprotective signaling by activated protein C requires protease-activated receptor-3 in podocytes

Thati Madhusudhan, Hongjie Wang, Beate K. Straub, Elisabeth Gröne, Qianxing Zhou, Khurrum Shahzad, Sandra Müller-Krebs, Vedat Schwenger, Bruce Gerlitz, Brian W. Grinnell, John H. Griffin, Jochen Reiser, Hermann-Josef Gröne, Charles T. Esmon, Peter P. Nawroth, Berend Isermann
Journal: Blood
Blood (2012) 119 (3): 874–883.
https://doi.org/10.1182/blood-2011-07-365973
Published: 2012
Includes: Supplemental data
Journal Articles

Activated Protein C Controls p66shc: A Novel Defense Mechanism in Diabetic Nephropathy

Fabian M Bock, Khurrum Shahzad, Ph.D., Thati Madhusudhan, Ph.D., Hongjie Wang, Peter P Nawroth, MD, Berend H. Isermann, MD
Journal: Blood
Blood (2011) 118 (21): 2204.
https://doi.org/10.1182/blood.V118.21.2204.2204
Published: 2011
Journal Articles

Intermediate Thrombin Activation Is Associated with Reduced Cardiovascular Death Independently of Markers of Lipid Metabolism and Inflammation

Berend H. Isermann, MD, Jochen Schneider, MD, Marcus E Kleber, Ph.D., Hongjie Wang, Bernhard O Boehm, MD, Tanja B Grammer, MD, Florian Prüller, MD, Peter P Nawroth, MD, Winfried März, MD
Journal: Blood
Blood (2011) 118 (21): 31.
https://doi.org/10.1182/blood.V118.21.31.31
Published: 2011
Journal Articles

Low but sustained coagulation activation ameliorates glucose-induced podocyte apoptosis: protective effect of factor V Leiden in diabetic nephropathy

Hongjie Wang, Thati Madhusudhan, Tao He, Björn Hummel, Simone Schmidt, Ilya A. Vinnikov, Khurrum Shahzad, Muhammed Kashif, Sandra Muller-Krebs, Vedat Schwenger, Angelika Bierhaus, Gottfried Rudofsky, Peter P. Nawroth, Berend Isermann
Journal: Blood
Blood (2011) 117 (19): 5231–5242.
https://doi.org/10.1182/blood-2010-10-314773
Published: 2011
Includes: Supplemental data
Journal Articles

RAGE and ICAM-1 cooperate in mediating leukocyte recruitment during acute inflammation in vivo

David Frommhold, Anna Kamphues, Ingrid Hepper, Monika Pruenster, Ivan K. Lukić, Ines Socher, Victoria Zablotskaya, Kirsten Buschmann, Baerbel Lange-Sperandio, Jürgen Schymeinsky, Eduard Ryschich, Johannes Poeschl, Christian Kupatt, Peter P. Nawroth, Markus Moser, Barbara Walzog, Angelika Bierhaus, Markus Sperandio
Journal: Blood
Blood (2010) 116 (5): 841–849.
https://doi.org/10.1182/blood-2009-09-244293
Published: 2010
Includes: Multimedia, Supplemental data
Journal Articles

The extracellular adherence protein (Eap) of Staphylococcus aureus inhibits wound healing by interfering with host defense and repair mechanisms

Athanasios N. Athanasopoulos, Matina Economopoulou, Valeria V. Orlova, Astrid Sobke, Darius Schneider, Holger Weber, Hellmut G. Augustin, Sabine A. Eming, Uwe Schubert, Thomas Linn, Peter P. Nawroth, Muzaffar Hussain, Hans-Peter Hammes, Mathias Herrmann, Klaus T. Preissner, Triantafyllos Chavakis
Journal: Blood
Blood (2006) 107 (7): 2720–2727.
https://doi.org/10.1182/blood-2005-08-3140
Published: 2006
Journal Articles

Loss of TM-Dependent PC-Activation Predisposes to Diabetic Nephropathy: Potential Role of Endothelial Apoptosis.

Berend Isermann, MD, Madhusudhan Thati, Ilya Vinnikov, MD, Stefanie Herzog, Sina Huntscha, Robert Bünder, MD, Hartmut Weiler, PhD, Angelika Bierhaus, PhD, Peter P. Nawroth, MD
Journal: Blood
Blood (2005) 106 (11): 1029.
https://doi.org/10.1182/blood.V106.11.1029.1029
Published: 2005
Journal Articles

Angiostatin is a novel anti-inflammatory factor by inhibiting leukocyte recruitment

Triantafyllos Chavakis, Athanasios Athanasopoulos, Joong-Sup Rhee, Valeria Orlova, Thomas Schmidt-Wöll, Angelika Bierhaus, Andreas E. May, Ilhan Celik, Peter P. Nawroth, Klaus T. Preissner
Journal: Blood
Blood (2005) 105 (3): 1036–1043.
https://doi.org/10.1182/blood-2004-01-0166
Published: 2005
Journal Articles

Identification of Four Genes in Endothelial Cells Whose Expression Is Affected by Tumor Cells and Host Immune Status—A Study in Ex Vivo–Isolated Endothelial Cells

Birgit Liliensiek, Marian Rocha, Victor Umansky, Axel Benner, Jie Lin, Reinhard Ziegler, Peter P. Nawroth, Volker Schirrmacher
Journal: Blood
Blood (1998) 92 (9): 3394–3404.
https://doi.org/10.1182/blood.V92.9.3394
Published: 1998