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Poonkuzhali Balasubramanian
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Journal Articles

Rationalization of Anti-PD-1 Therapy Using Receptor Occupancy Data to Guide Drug Dosing - a Single Arm Phase II Trial Using Immunomodulation in Relapsed/Refractory Hodgkin Lymphoma

Anu Korula, Arun Arunachalam, Uday Kulkarni, Phaneendra Venkateswara Rao Datari, Sumith Mathew, Aswin Anand PAI, Sushil Selvarajan, Fouzia N., Aby Abraham, Biju George, Poonkuzhali Balasubramanian, Vikram Mathews
Journal: Blood
Blood (2024) 144 (Supplement 1): 647.
https://doi.org/10.1182/blood-2024-201172
Published: 2024
Journal Articles

EASIX d0 Predicts Early Transplant-Related Mortality in Patients Undergoing Haploidentical Transplantation with Post-Transplant Cyclophosphamide-Mycophenolate Mofetil-Based GvHD Prophylaxis

Aswin Anand Pai, Nieshanth Parthiban, Nayanthara Bijukumar, Rachel Mariam Renji, Manoj A, Sujith Karumathil, Kavitha M Lakshmi, Sushil Selvarajan, Anu Korula, Fouzia NA, Aby Abraham, Alok Srivastava, Vikram Mathews, Biju George, Uday Kulkarni, Poonkuzhali Balasubramanian
Journal: Blood
Blood (2024) 144 (Supplement 1): 4879.
https://doi.org/10.1182/blood-2024-201901
Published: 2024
Journal Articles

Lower Mycophenolic Acid Exposure in Patients Undergoing Haploidentical Stem Cell Transplantation with Post-Transplant Cyclophosphamide/ Cyclosporine a-Based GvHD Prophylaxis - Need for Dose Intensification

Aswin Anand Pai, John C Panetta, Nayanthara Bijukumar, Rachel Mariam Renji, Manoj A, Agila Jayaraman, Sujith Karumathil, Anu Korula, Sushil Selvarajan, Alok Srivastava, Aby Abraham, Vikram Mathews, Biju George, Uday Kulkarni, Poonkuzhali Balasubramanian
Journal: Blood
Blood (2024) 144 (Supplement 1): 2150.
https://doi.org/10.1182/blood-2024-203105
Published: 2024
Journal Articles

Targeting Cholesterol Homeostasis Pathway to Overcome Acquired Cytarabine Resistance in Acute Myeloid Leukemia

Saswati Das, Raveen Stephen Stallon Illangeswaran, Daniel Zechariah Paul Zechariah Paul Jebanesan, Rakhi Thalayatta Vidhyadharan, Vikram Mathews, Shaji Ramachandran Velayudhan, Poonkuzhali Balasubramanian
Journal: Blood
Blood (2022) 140 (Supplement 1): 11543.
https://doi.org/10.1182/blood-2022-168776
Published: 2022
Journal Articles

Efficient Knock-out of Serine Protease Cathepsin G Enhances Chemosensitivity to Cytarabine By Modulating the Cytarabine Metabolic Pathway Genes in Acute Myeloid Leukemia

Saswati Das, Raveen Stephen Stallon Illangeswaran, Daniel Zechariah Paul Jebanesan, Esther Sathya Bama Benjamin, Rakhi Thalayatta Vidhyadharan, Vikram Mathews, Shaji Ramachandran Velayudhan, Poonkuzhali Balasubramanian
Journal: Blood
Blood (2022) 140 (Supplement 1): 11542.
https://doi.org/10.1182/blood-2022-168817
Published: 2022
Journal Articles

Intracranial Bleeding in Acute Promyelocytic Leukemia Treated with Arsenic Trioxide-Based Regimens: Impact on Relapse and Survival

Uday Prakash Kulkarni, Sushil Selvarajan, Fouzia NA, Sharon Lionel, Sukesh C Nair, Poonkuzhali Balasubramanian, Thenmozhi Mani, Aby Abraham, Biju George, Vikram Mathews
Journal: Blood
Blood (2022) 140 (Supplement 1): 8917–8918.
https://doi.org/10.1182/blood-2022-168649
Published: 2022
Journal Articles

Population Pharmacokinetics of Mycophenolic Acid in Haploidentical Transplant Recipients Receiving Post-Transplant Cyclophosphamide Based GvHD Prophylaxis

Aswin Anand PAI, Uday Kulkarni, Binu Susan Mathew, Nayanthara KB, John C Panetta, Sujith Karumathil, Aby Abraham, Vikram Mathews, Biju George, Poonkuzhali Balasubramanian
Journal: Blood
Blood (2022) 140 (Supplement 1): 10473–10474.
https://doi.org/10.1182/blood-2022-168894
Published: 2022
Journal Articles

A Model-Informed Precision Busulfan Dosing in Pediatric Patients Undergoing Hematopoietic Cell Transplantation- Real-World Data

Poonkuzhali Balasubramanian, Aswin Anand PAI, Rajesh Nagarajan, Stephanie Hughes, Eunice Sindhuvi Edison, Uday Prakash Kulkarni, Aby Abraham, Alok Srivastava, Vikram Mathews, Biju George
Journal: Blood
Blood (2022) 140 (Supplement 1): 4743–4744.
https://doi.org/10.1182/blood-2022-166959
Published: 2022
Journal Articles

Rxra Overexpression Improves the Sensitivity to Imatinib I n-Vitro/in-Vivo By Disrupting the Oxidative Capacity of Chronic Myeloid Leukemia Cells

Raveen Stephen Stallon Illangeswaran, Bharathi M Rajamani, Esther Sathya Bama Benjamin, Saswati Das, Daniel Zechariah Paul Jebanesan, Vikram Mathews, Shaji Ramachandran Velayudhan, Poonkuzhali Balasubramanian
Journal: Blood
Blood (2022) 140 (Supplement 1): 9595–9596.
https://doi.org/10.1182/blood-2022-168634
Published: 2022
Journal Articles

Low Dose Dasatinib Is Not As Active in a CML CP Cohort Enriched with Intermediate/High-Risk CML Chronic Phase: A Phase IIb Multi-Center Trial

Aby Abraham, Hasmukh Jain, Jina Bhattacharyya, Dubashi Biswajit, Jayachandran PK, Dinesh Bhurani, Stalin Chowdary Bala, Suman Pramanik, Santhosh Devadas, Uday Prakash Kulkarni, Manju Sengar, Rayaz Ahmed, Thenmozhi Mani, Damodar Das, Parathan Karunakaran, Sadashivudu Gundeti, Rasmi Pallasseri, Nikhil Patkar, Manjunath Nookala, Smita Kayal, Poonkuzhali Balasubramanian
Journal: Blood
Blood (2022) 140 (Supplement 1): 6789–6790.
https://doi.org/10.1182/blood-2022-169777
Published: 2022
Journal Articles

Real-World Outcomes for Acute Promyelocytic Leukemia: Need to Address Induction Mortality

Manju Sengar, Hasmukh Jain, Uday Prakash Kulkarni, Vasu Babu Goli, Anu Korula, Prasanna Samuel, Sushil Selvarajan, Lingaraj Nayak, Aby Abraham, Om Prakash, Fouzia N., Saranya Kumaran, Jayashree Thorat, Bhausaheb Bagal, Poonkuzhali Balasubramanian, Dhanlaxmi Shetty, Nikhil Patkar, Biju George, Vikram Mathews
Journal: Blood
Blood (2022) 140 (Supplement 1): 3244–3245.
https://doi.org/10.1182/blood-2022-167202
Published: 2022
Journal Articles

Real World Data of Concurrent Arsenic Trioxide and All-Trans Retinoic Acid with Minimal Use of Anthracycline in the Treatment of Acute Promyelocytic Leukemia

Uday Prakash Kulkarni, Sushil Selvarajan, Sharon Lionel, Mithun Abraham Prakash, Hamenth Kumar Palani, Nithya Balasundaram, Arvind Venkatraman, Anu Korula, Anup J Devasia, Fouzia NA, Nancy Beryl Janet, Sukesh Chandran Nair, Aby Abraham, Thenmozhi Mani, Jeyaseelan Lakshmanan, Arun Kumar Arunachalam, Poonkuzhali Balasubramanian, Biju George, Vikram Mathews
Journal: Blood
Blood (2021) 138 (Supplement 1): 2338.
https://doi.org/10.1182/blood-2021-146362
Published: 2021
Journal Articles

Combining Arsenic Trioxide and Mitocans Selectively Disrupts Cellular Energetics in Acute Myeloid Leukemia

Nithya Balasundaram, Arvind Venkatraman, Yolanda Augustin, Hamenth Kumar Palani, Swathy Palanikumar, Nair Reeshma Radhakrishnan, Anu Korula, Uday Prakash Kulkarni, Poonkuzhali Balasubramanian, Eunice Sindhuvi, Biju George, Sanjeev Krishna, Vikram Mathews
Journal: Blood
Blood (2021) 138 (Supplement 1): 2245.
https://doi.org/10.1182/blood-2021-150038
Published: 2021
Journal Articles

Endothelial Activation and Stress Index (EASIX) Measured Pre-Transplant Identifies a Subgroup with High Transplant Related Mortality in Patients with Thalassemia Undergoing Stem Cell Transplantation Using Thiotepa-Treosulfan-Fludarabine Conditioning

Uday Prakash Kulkarni, Aswin Anand Pai, Kavitha M Lakshmi, Sushil Selvarajan, Sharon Lionel, Anup J Devasia, Anu Korula, Fouzia NA, Eunice Sindhuvi, Aby Abraham, Alok Srivastava, Vikram Mathews, Biju George, Poonkuzhali Balasubramanian
Journal: Blood
Blood (2021) 138 (Supplement 1): 1781.
https://doi.org/10.1182/blood-2021-152153
Published: 2021
Journal Articles

Genetic Ablation of Nuclear Receptor Interacting Protein 1 (NRIP1) Sensitizes Acute Myeloid Leukemia Cells to Retinoic Acids

Raveen Stephen Stallon Illangeswaran, Sreeja Karathedath, Abhirup Bagchi, Bharathi M Rajamani, Balaji Balakrishnan, Vikram Mathews, Shaji Ramachandran Velayudhan, Poonkuzhali Balasubramanian
Journal: Blood
Blood (2021) 138 (Supplement 1): 1146.
https://doi.org/10.1182/blood-2021-152058
Published: 2021
Journal Articles

Haploidentical Natural Killer Cell Therapy As an Adjunct to Stem Cell Transplantation for Refractory Acute Myeloid Leukemia

Uday Prakash Kulkarni, Arun Kumar Arunachalam, Hamenth Kumar Palani, Nithya Balasundaram, Arvind Venkatraman, Anu Korula, Anup J Devasia, Fouzia NA, Sushil Selvarajan, Sharon Lionel, Madhavi Maddali, Aby Abraham, Poonkuzhali Balasubramanian, Biju George, Vikram Mathews
Journal: Blood
Blood (2021) 138 (Supplement 1): 3827.
https://doi.org/10.1182/blood-2021-149539
Published: 2021
Journal Articles

Treosulfan Metabolite (S, S-EBDM) Pharmacokinetics Influences Regimen Related Toxicity in Patients with Beta Thalassaemia Major Undergoing HSCT

Aswin Anand PAI, MSc, John C Panetta, PhD, Ezhil Pavai Mohanan, PhD, Raveen Stephen Stallon Illangeswaran, MSc, Balaji Balakrishnan, PhD, Eunice Sindhuvi Edison, PhD, Kavitha M Lakshmi, MSc, Uday Prakash Kulkarni, MD DM, Anup Joseph Devasia, MD DM, Fouzia N., Anu Korula, MD DM, Aby Abraham, MD DM, Biju George, MDDM, Vikram Mathews, MD DM, Alok Srivastava, MD,FRACP,FRCPA, Poonkuzhali Balasubramanian, PhD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1977.
https://doi.org/10.1182/blood-2019-125604
Published: 2019
Journal Articles

Targeting Extracellular Vesicle Secretion As a Strategy to Overcome Microenvironment Mediated Drug Resistance in Acute Myeloid Leukemia

Palani Kumar Kumar, PhD, Saravanan Ganesan, PhD, Nithya Balasundaram, MSc, Sachin David, M.Sc, Arvind Venkatraman, M.Tech, Uday Prakash Kulkarni, MD DM, Anu Korula, MD DM, Biju George, MDDM, Poonkuzhali Balasubramanian, PhD, Vikram Mathews, MD DM
Journal: Blood
Blood (2019) 134 (Supplement_1): 3733.
https://doi.org/10.1182/blood-2019-126389
Published: 2019
Journal Articles

Induction Related Mortality in Acute Myeloid Leukemia: Multivariate Model of Predictive Score from the Indian Acute Leukemia Research Database (INwARD) of the Hematology Cancer Consortium (HCC)

Smita Kayal, MD DM, Manju Sengar, MD DM, Hasmukh Jain, MD DM, Avinash Bonda, MD DM, Biju George, MDDM, Uday Prakash Kulkarni, MD DM, Poonkuzhali Balasubramanian, PhD, Dinesh Bhurani, MD DM, FRCPA, Rayaz Ahmed, MDDM, Dubashi Biswajit, MD DNB, DM, Jayachandran PK, MD MRCP, DM, Ankit Batra, MD, Suman Kumar, MD DM, Kundan Mishra, MD DM, Jina Bhattacharyya, MD DM, Chepsy C Philip, MD, Maitreyee Bhattacharyya, MD DM, Lokanatha Dasappa, MD, K Govind Babu, MD DM, Smitha Carol Saldanha, DM, MBBS, MD, Atul Sharma, MD DM, Jeyaseelan Lakshmanan, PhD, Jothilakshmi Durairaj, M.Sc., Vishnu Vardhan Rudravaram, PhD, Vikram Mathews, MD DM, Rajan Kapoor, MD DM
Journal: Blood
Blood (2019) 134 (Supplement_1): 2615.
https://doi.org/10.1182/blood-2019-127623
Published: 2019
Journal Articles

Hematological Cancer Consortium: Multi-Center Acute Myeloid Leukemia Registry Data from India

Rajan Kapoor, MD DM, Hasmukh Jain, MD DM, Anu Korula, MD DM, Dinesh Bhurani, MD DM, FRCPA, Venkatraman Radhakrishnan, MD DM, Chepsy C Philip, MD, Jina Bhattacharyya, MD, Maitreyee Bhattacharyya, DM, Smita Kayal, MD, Pankaj Malhotra, MD, Govind Babu, MD DM, Lalit Kumar, MD DM, Om Prakash, MSc, Ambily Nadaraj, MSc, Jeyaseelan Lakshmanan, PhD, Biju George, DM, Poonkuzhali Balasubramanian, MSc, Bhausaheb Bagal, MD DM, Satyaranjan Das, MD, Rayaz Ahmed, MD DM, Prasanth Ganesan, MD DM, Gaurav Prakash, MD DM, Nikita Mehra, MD DM, Manju Sengar, MD DM, Vikram Mathews, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4006.
https://doi.org/10.1182/blood-2018-99-116853
Published: 2018