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Journal Articles

AAV-mediated gene transfer in the perinatal period results in expression of FVII at levels that protect against fatal spontaneous hemorrhage

Christopher Binny, Jenny McIntosh, Marco Della Peruta, Hanna Kymalainen, Edward G. D. Tuddenham, Suzanne M. K. Buckley, Simon N. Waddington, John H. McVey, Yunyu Spence, Christopher L. Morton, Adrian J. Thrasher, John T. Gray, Francis J. Castellino, Alice F. Tarantal, Andrew M. Davidoff, Amit C. Nathwani

Blood (2012) 119 (4): 957–966.

https://doi.org/10.1182/blood-2011-09-377630

Published: 2012

Includes: Supplemental data

Journal Articles

Codon optimization of human factor VIII cDNAs leads to high-level expression

Natalie J. Ward, Suzanne M. K. Buckley, Simon N. Waddington, Thierry VandenDriessche, Marinee K. L. Chuah, Amit C. Nathwani, Jenny McIntosh, Edward G. D. Tuddenham, Christine Kinnon, Adrian J. Thrasher, John H. McVey

Blood (2011) 117 (3): 798–807.

https://doi.org/10.1182/blood-2010-05-282707

Published: 2011

Includes: Supplemental data

Journal Articles

Biodistribution and retargeting of FX-binding ablated adenovirus serotype 5 vectors

Raul Alba, Angela C. Bradshaw, Lynda Coughlan, Laura Denby, Robert A. McDonald, Simon N. Waddington, Suzanne M. K. Buckley, Jenny A. Greig, Alan L. Parker, Ashley M. Miller, Hongjie Wang, Andre Lieber, Nico van Rooijen, John H. McVey, Stuart A. Nicklin, Andrew H. Baker

Blood (2010) 116 (15): 2656–2664.

https://doi.org/10.1182/blood-2009-12-260026

Published: 2010

Includes: Supplemental data

Journal Articles

Identification of coagulation factor (F)X binding sites on the adenovirus serotype 5 hexon: effect of mutagenesis on FX interactions and gene transfer

Raul Alba, Angela C. Bradshaw, Alan L. Parker, David Bhella, Simon N. Waddington, Stuart A. Nicklin, Nico van Rooijen, Jerome Custers, Jaap Goudsmit, Dan H. Barouch, John H. McVey, Andrew H. Baker

Blood (2009) 114 (5): 965–971.

https://doi.org/10.1182/blood-2009-03-208835

Published: 2009

Includes: Supplemental data

Journal Articles

Multiple vitamin K-dependent coagulation zymogens promote adenovirus-mediated gene delivery to hepatocytes

Alan L. Parker, Simon N. Waddington, Campbell G. Nicol, Dmitry M. Shayakhmetov, Suzanne M. Buckley, Laura Denby, Geoffrey Kemball-Cook, Shaoheng Ni, Andre Lieber, John H. McVey, Stuart A. Nicklin, Andrew H. Baker

Blood (2006) 108 (8): 2554–2561.

https://doi.org/10.1182/blood-2006-04-008532

Published: 2006

Journal Articles

Self-complementary adeno-associated virus vectors containing a novel liver-specific human factor IX expression cassette enable highly efficient transduction of murine and nonhuman primate liver

Amit C. Nathwani, John T. Gray, Catherine Y. C. Ng, Junfang Zhou, Yunyu Spence, Simon N. Waddington, Edward G. D. Tuddenham, Geoffrey Kemball-Cook, Jenny McIntosh, Mariette Boon-Spijker, Koen Mertens, Andrew M. Davidoff

Blood (2006) 107 (7): 2653–2661.

https://doi.org/10.1182/blood-2005-10-4035

Published: 2006

Includes: Supplemental data

Journal Articles

Permanent phenotypic correction of hemophilia B in immunocompetent mice by prenatal gene therapy

Blood (2004) 104 (9): 2714–2721.

https://doi.org/10.1182/blood-2004-02-0627

Published: 2004

Journal Articles

In utero gene transfer of human factor IX to fetal mice can induce postnatal tolerance of the exogenous clotting factor

Simon N. Waddington, Suzanne M. K. Buckley, Megha Nivsarkar, Sarah Jezzard, Holm Schneider, Thomas Dahse, Geoff Kemball-Cook, Maznu Miah, Nick Tucker, Margaret J. Dallman, Mike Themis, Charles Coutelle

Blood (2003) 101 (4): 1359–1366.

https://doi.org/10.1182/blood-2002-03-0779

Published: 2003

NARROW

AAV-mediated gene transfer in the perinatal period results in expression of FVII at levels that protect against fatal spontaneous hemorrhage

Codon optimization of human factor VIII cDNAs leads to high-level expression

Biodistribution and retargeting of FX-binding ablated adenovirus serotype 5 vectors

Identification of coagulation factor (F)X binding sites on the adenovirus serotype 5 hexon: effect of mutagenesis on FX interactions and gene transfer

Multiple vitamin K-dependent coagulation zymogens promote adenovirus-mediated gene delivery to hepatocytes

Self-complementary adeno-associated virus vectors containing a novel liver-specific human factor IX expression cassette enable highly efficient transduction of murine and nonhuman primate liver

Permanent phenotypic correction of hemophilia B in immunocompetent mice by prenatal gene therapy

In utero gene transfer of human factor IX to fetal mice can induce postnatal tolerance of the exogenous clotting factor

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American Society of Hematology

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ASH Publications

American Society of Hematology

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