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Issue Archive

Volume 123, Issue 22
May 29 2014
Issue Cover

Table of Contents

INSIDE BLOOD COMMENTARIES

INSIDE BLOOD COMMENTARY
Of mice and men…
James Palis
View Articletitled, Of mice and men…
INSIDE BLOOD COMMENTARY
CLL and NHL: the end of chemotherapy?
Clinical Trials & Observations
Bruce D. Cheson
View Articletitled, CLL and NHL: the end of chemotherapy?
INSIDE BLOOD COMMENTARY
p57Kip2 regulates T-cell development and lymphoma
Senthil Raja Jayapal,Philipp Kaldis
View Articletitled, p57<sup>Kip2</sup> regulates T-cell development and lymphoma
INSIDE BLOOD COMMENTARY
The missing link in early follicular lymphoma development
Philip M. Kluin
View Articletitled, The missing link in early follicular lymphoma development
INSIDE BLOOD COMMENTARY
A(nother) day in the life of neonatal platelets
Spencer K. Sullivan,Mortimer Poncz
View Articletitled, A(nother) day in the life of neonatal platelets
INSIDE BLOOD COMMENTARY
Antibodies in APS with competing interest
B. de Laat
View Articletitled, Antibodies in APS with competing interest
INSIDE BLOOD COMMENTARY
Bye-bye TRALI: by understanding and innovation
Beth H. Shaz
View Articletitled, Bye-bye TRALI: by understanding and innovation
INSIDE BLOOD COMMENTARY
Siglec-G signaling DAMPens GVHD
Robert Zeiser
View Articletitled, Siglec-G signaling DAMPens GVHD

BLOOD WORK

Diffuse large B-cell lymphoma in leukemic phase with flower cell morphology
Eric Wong,Surender Juneja
View Articletitled, Diffuse large B-cell lymphoma in leukemic phase with flower cell morphology
Disseminated fusariosis during acute myelogenous leukemia induction treatment
Amitkumar Mehta,Naresh Bellam
View Articletitled, Disseminated fusariosis during acute myelogenous leukemia induction treatment

PLENARY PAPER

Expansion of the neonatal platelet mass is achieved via an extension of platelet lifespan
Zhi-Jian Liu,Karin M. Hoffmeister,Zhongbo Hu,Donald E. Mager,Sihem Ait-Oudhia,Marlyse A. Debrincat,Irina Pleines,Emma C. Josefsson,Benjamin T. Kile,Joseph Italiano, Jr,Haley Ramsey,Renata Grozovsky,Peter Veng-Pedersen,Chaitanya Chavda,Martha Sola-Visner
View Articletitled, Expansion of the neonatal platelet mass is achieved via an extension of platelet lifespan
Supplemental data

CLINICAL TRIALS AND OBSERVATIONS

Idelalisib, an inhibitor of phosphatidylinositol 3-kinase p110δ, for relapsed/refractory chronic lymphocytic leukemia
Clinical Trials & Observations
Jennifer R. Brown,John C. Byrd,Steven E. Coutre,Don M. Benson,Ian W. Flinn,Nina D. Wagner-Johnston,Stephen E. Spurgeon,Brad S. Kahl,Celeste Bello,Heather K. Webb,Dave M. Johnson,Sissy Peterman,Daniel Li,Thomas M. Jahn,Brian J. Lannutti,Roger G. Ulrich,Albert S. Yu,Langdon L. Miller,Richard R. Furman
View Articletitled, Idelalisib, an inhibitor of phosphatidylinositol 3-kinase p110δ, for relapsed/refractory chronic lymphocytic leukemia
Supplemental data
A phase 1 study of the PI3Kδ inhibitor idelalisib in patients with relapsed/refractory mantle cell lymphoma (MCL)
Clinical Trials & Observations
Brad S. Kahl,Stephen E. Spurgeon,Richard R. Furman,Ian W. Flinn,Steven E. Coutre,Jennifer R. Brown,Don M. Benson,John C. Byrd,Sissy Peterman,Yoonjin Cho,Albert Yu,Wayne R. Godfrey,Nina D. Wagner-Johnston
View Articletitled, A phase 1 study of the PI3Kδ inhibitor idelalisib in patients with relapsed/refractory mantle cell lymphoma (MCL)
Idelalisib, a selective inhibitor of phosphatidylinositol 3-kinase-δ, as therapy for previously treated indolent non-Hodgkin lymphoma
Clinical Trials & Observations
Ian W. Flinn,Brad S. Kahl,John P. Leonard,Richard R. Furman,Jennifer R. Brown,John C. Byrd,Nina D. Wagner-Johnston,Steve E. Coutre,Don M. Benson,Sissy Peterman,Yoonjin Cho,Heather K. Webb,David M. Johnson,Albert S. Yu,Roger G. Ulrich,Wayne R. Godfrey,Langdon L. Miller,Stephen E. Spurgeon
View Articletitled, Idelalisib, a selective inhibitor of phosphatidylinositol 3-kinase-δ, as therapy for previously treated indolent non-Hodgkin lymphoma
Serum free immunoglobulin light chain evaluation as a marker of impact from intraclonal heterogeneity on myeloma outcome
Clinical Trials & Observations
Annamaria Brioli,Hannah Giles,Charlotte Pawlyn,John P. Campbell,Martin F. Kaiser,Lorenzo Melchor,Graham H. Jackson,Walter M. Gregory,Roger G. Owen,J. Anthony Child,Faith E. Davies,Michele Cavo,Mark T. Drayson,Gareth J. Morgan
View Articletitled, Serum free immunoglobulin light chain evaluation as a marker of impact from intraclonal heterogeneity on myeloma outcome

IMMUNOBIOLOGY

Id2 represses E2A-mediated activation of IL-10 expression in T cells
Frederick Masson,Margherita Ghisi,Joanna R. Groom,Axel Kallies,Cyril Seillet,Ricky W. Johnstone,Stephen L. Nutt,Gabrielle T. Belz
View Articletitled, Id2 represses E2A-mediated activation of IL-10 expression in T cells

LYMPHOID NEOPLASIA

p57 regulates T-cell development and prevents lymphomagenesis by balancing p53 activity and pre-TCR signaling
Akinobu Matsumoto,Shoichiro Takeishi,Keiichi I. Nakayama
View Articletitled, p57 regulates T-cell development and prevents lymphomagenesis by balancing p53 activity and pre-TCR signaling
Supplemental data
One siRNA pool targeting the λ constant region stops λ light-chain production and causes terminal endoplasmic reticulum stress
Ping Zhou,Xun Ma,Lakshmanan Iyer,Chakra Chaulagain,Raymond L. Comenzo
View Articletitled, One siRNA pool targeting the λ constant region stops λ light-chain production and causes terminal endoplasmic reticulum stress
Supplemental data
SATB1 overexpression promotes malignant T-cell proliferation in cutaneous CD30+ lymphoproliferative disease by repressing p21
Yang Wang,Xiaoguang Gu,Gaolei Zhang,Lin Wang,Tingting Wang,Yun Zhao,Xiuyan Zhang,Youwen Zhou,Marshall Kadin,Ping Tu
View Articletitled, SATB1 overexpression promotes malignant T-cell proliferation in cutaneous CD30<sup>+</sup> lymphoproliferative disease by repressing p21
Supplemental data
Human t(14;18)positive germinal center B cells: a new step in follicular lymphoma pathogenesis?
Brief Report
Julie Tellier,Cedric Menard,Sandrine Roulland,Nadine Martin,Céline Monvoisin,Lionel Chasson,Bertrand Nadel,Philippe Gaulard,Claudine Schiff,Karin Tarte
View Articletitled, Human t(14;18)positive germinal center B cells: a new step in follicular lymphoma pathogenesis?
Supplemental data

MYELOID NEOPLASIA

Integrated genomic analysis illustrates the central role of JAK-STAT pathway activation in myeloproliferative neoplasm pathogenesis
e-blood
Raajit Rampal,Fatima Al-Shahrour,Omar Abdel-Wahab,Jay P. Patel,Jean-Philippe Brunel,Craig H. Mermel,Adam J. Bass,Jennifer Pretz,Jihae Ahn,Todd Hricik,Outi Kilpivaara,Martha Wadleigh,Lambert Busque,D. Gary Gilliland,Todd R. Golub,Benjamin L. Ebert,Ross L. Levine
View Articletitled, Integrated genomic analysis illustrates the central role of JAK-STAT pathway activation in myeloproliferative neoplasm pathogenesis
Supplemental data

RED CELLS, IRON, AND ERYTHROPOIESIS

Global transcriptome analyses of human and murine terminal erythroid differentiation
Xiuli An,Vincent P. Schulz,Jie Li,Kunlu Wu,Jing Liu,Fumin Xue,Jingping Hu,Narla Mohandas,Patrick G. Gallagher
View Articletitled, Global transcriptome analyses of human and murine terminal erythroid differentiation
Supplemental data

THROMBOSIS AND HEMOSTASIS

A non–complement-fixing antibody to β2 glycoprotein I as a novel therapy for antiphospholipid syndrome
Chiara Agostinis,Paolo Durigutto,Daniele Sblattero,Maria O. Borghi,Claudia Grossi,Filomena Guida,Roberta Bulla,Paolo Macor,Francesca Pregnolato,Pier Luigi Meroni,Francesco Tedesco
View Articletitled, A non–complement-fixing antibody to β2 glycoprotein I as a novel therapy for antiphospholipid syndrome
Supplemental data

TRANSFUSION MEDICINE

Experimental prestorage filtration removes antibodies and decreases lipids in RBC supernatants mitigating TRALI in vivo
Christopher C. Silliman,Marguerite R. Kelher,Samina Y. Khan,Monica LaSarre,F. Bernadette West,Kevin J. Land,Barbara Mish,Linda Ceriano,Samuel Sowemimo-Coker
View Articletitled, Experimental prestorage filtration removes antibodies and decreases lipids in RBC supernatants mitigating TRALI in vivo
Peripheral blood monocyte-derived chemokine blockade prevents murine transfusion-related acute lung injury (TRALI)
Christopher G. J. McKenzie,Michael Kim,Tarandeep K. Singh,Youli Milev,John Freedman,John W. Semple
View Articletitled, Peripheral blood monocyte-derived chemokine blockade prevents murine transfusion-related acute lung injury (TRALI)
Supplemental data

TRANSPLANTATION

Effect of body mass in children with hematologic malignancies undergoing allogeneic bone marrow transplantation
Richard Aplenc,Mei-Jie Zhang,Lillian Sung,Xiaochun Zhu,Vincent T. Ho,Kenneth Cooke,Christopher Dvorak,Gregory Hale,Luis M. Isola,Hillard M. Lazarus,Philip L. McCarthy,Richard Olsson,Michael Pulsipher,Marcelo C. Pasquini,Nancy Bunin,on behalf of the Regimen-Related Toxicity Working Committee, Center for International Blood and Marrow Transplant Research,on behalf of the Regimen-Related Toxicity Working Committee, Center for International Blood and Marrow Transplant Research,on behalf of the Regimen-Related Toxicity Working Committee, Center for International Blood and Marrow Transplant Research,on behalf of the Regimen-Related Toxicity Working Committee, Center for International Blood and Marrow Transplant Research,on behalf of the Regimen-Related Toxicity Working Committee, Center for International Blood and Marrow Transplant Research,on behalf of the Regimen-Related Toxicity Working Committee, Center for International Blood and Marrow Transplant Research,on behalf of the Regimen-Related Toxicity Working Committee, Center for International Blood and Marrow Transplant Research,on behalf of the Regimen-Related Toxicity Working Committee, Center for International Blood and Marrow Transplant Research,on behalf of the Regimen-Related Toxicity Working Committee, Center for International Blood and Marrow Transplant Research,on behalf of the Regimen-Related Toxicity Working Committee, Center for International Blood and Marrow Transplant Research,on behalf of the Regimen-Related Toxicity Working Committee, Center for International Blood and Marrow Transplant Research,on behalf of the Regimen-Related Toxicity Working Committee, Center for International Blood and Marrow Transplant Research,on behalf of the Regimen-Related Toxicity Working Committee, Center for International Blood and Marrow Transplant Research,on behalf of the Regimen-Related Toxicity Working Committee, Center for International Blood and Marrow Transplant Research,on behalf of the Regimen-Related Toxicity Working Committee, Center for International Blood and Marrow Transplant Research
View Articletitled, Effect of body mass in children with hematologic malignancies undergoing allogeneic bone marrow transplantation
Supplemental data
Siglec-G–CD24 axis controls the severity of graft-versus-host disease in mice
Tomomi Toubai,Guoqing Hou,Nathan Mathewson,Chen Liu,Ying Wang,Katherine Oravecz-Wilson,Emily Cummings,Corinne Rossi,Rebecca Evers,Yaping Sun,Julia Wu,Sung Won Choi,Dexing Fang,Pan Zheng,Yang Liu,Pavan Reddy
View Articletitled, Siglec-G–CD24 axis controls the severity of graft-versus-host disease in mice
Supplemental data
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