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Issue Archive

Volume 125, Issue 19
May 7 2015
Issue Cover

Table of Contents

INSIDE BLOOD COMMENTARIES

INSIDE BLOOD COMMENTARY
Making a little go a long way…
Stella M. Davies
View Articletitled, Making a little go a long way…
INSIDE BLOOD COMMENTARY
Targeted drugs in concert with chemo: opposites attract
Clinical Trials & Observations
Clemens-Martin Wendtner,Kirsten Fischer
View Articletitled, Targeted drugs in concert with chemo: opposites attract
INSIDE BLOOD COMMENTARY
Ph+ ALL: drawing strength from a benign past
Markus Müschen
View Articletitled, <em>Ph</em><sup>+</sup> ALL: drawing strength from a benign past
INSIDE BLOOD COMMENTARY
Fish provide ID(H)eas on targeting leukemia
Eirini Trompouki
View Articletitled, Fish provide ID(H)eas on targeting leukemia
INSIDE BLOOD COMMENTARY
VWF propeptide in defining VWD subtypes
Sandra L. Haberichter
View Articletitled, VWF propeptide in defining VWD subtypes
INSIDE BLOOD COMMENTARY
Sugar polymers exacerbate lung GVHD
Nathan Mathewson,Pavan Reddy
View Articletitled, Sugar polymers exacerbate lung GVHD

PLENARY PAPER

TRANSPLANTATION
Enforced fucosylation of cord blood hematopoietic cells accelerates neutrophil and platelet engraftment after transplantation
Uday Popat,Rohtesh S. Mehta,Katayoun Rezvani,Patricia Fox,Kayo Kondo,David Marin,Ian McNiece,Betul Oran,Chitra Hosing,Amanda Olson,Simrit Parmar,Nina Shah,Michael Andreeff,Partow Kebriaei,Indreshpal Kaur,Eric Yvon,Marcos de Lima,Laurence J. N. Cooper,Priti Tewari,Richard E. Champlin,Yago Nieto,Borje S. Andersson,Amin Alousi,Roy B. Jones,Muzaffar H. Qazilbash,Qaiser Bashir,Stefan Ciurea,Sairah Ahmed,Paolo Anderlini,Doyle Bosque,Catherine Bollard,Jeffrey J. Molldrem,Julianne Chen,Gabriela Rondon,Michael Thomas,Leonard Miller,Steve Wolpe,Paul Simmons,Simon Robinson,Patrick A. Zweidler-McKay,Elizabeth J. Shpall
View Articletitled, Enforced fucosylation of cord blood hematopoietic cells accelerates neutrophil and platelet engraftment after transplantation

BLOOD SPOTLIGHT

Macrophages and iron trafficking at the birth and death of red cells
Tamara Korolnek,Iqbal Hamza
View Articletitled, Macrophages and iron trafficking at the birth and death of red cells

REVIEW ARTICLE

Activated protein C: biased for translation
John H. Griffin,Berislav V. Zlokovic,Laurent O. Mosnier
View Articletitled, Activated protein C: biased for translation

HOW I TREAT

How I treat hemophagocytic lymphohistiocytosis in the adult patient
Clinical Trials & Observations
Alison M. Schram,Nancy Berliner
View Articletitled, How I treat hemophagocytic lymphohistiocytosis in the adult patient

CLINICAL TRIALS AND OBSERVATIONS

The Bruton tyrosine kinase inhibitor ibrutinib with chemoimmunotherapy in patients with chronic lymphocytic leukemia
Clinical Trials & Observations
Jennifer R. Brown,Jacqueline C. Barrientos,Paul M. Barr,Ian W. Flinn,Jan A. Burger,Anh Tran,Fong Clow,Danelle F. James,Thorsten Graef,Jonathan W. Friedberg,Kanti Rai,Susan O’Brien
View Articletitled, The Bruton tyrosine kinase inhibitor ibrutinib with chemoimmunotherapy in patients with chronic lymphocytic leukemia
Supplemental data
Vosaroxin and vosaroxin plus low-dose Ara-C (LDAC) vs low-dose Ara-C alone in older patients with acute myeloid leukemia
Clinical Trials & Observations
Mike Dennis,Nigel Russell,Robert K. Hills,Claire Hemmaway,Nicki Panoskaltsis,Mary-Frances McMullin,Lars Kjeldsen,Helen Dignum,Ian F. Thomas,Richard E. Clark,Don Milligan,Alan K. Burnett
View Articletitled, Vosaroxin and vosaroxin plus low-dose Ara-C (LDAC) vs low-dose Ara-C alone in older patients with acute myeloid leukemia
Supplemental data

HEMATOPOIESIS AND STEM CELLS

Autophagy is required for stem cell mobilization by G-CSF
Brief Report
Lucie Leveque-El Mouttie,Therese Vu,Katie E. Lineburg,Rachel D. Kuns,Frederik O. Bagger,Bianca E. Teal,Mary Lor,Glen M. Boyle,Claudia Bruedigam,Justine D. Mintern,Geoffrey R. Hill,Kelli P. A. MacDonald,Steven W. Lane
View Articletitled, Autophagy is required for stem cell mobilization by G-CSF
Supplemental data

IMMUNOBIOLOGY

Synergy between rapamycin and FLT3 ligand enhances plasmacytoid dendritic cell–dependent induction of CD4+CD25+FoxP3+ Treg
Moanaro Biswas,Debalina Sarkar,Sandeep R. P. Kumar,Sushrusha Nayak,Geoffrey L. Rogers,David M. Markusic,Gongxian Liao,Cox Terhorst,Roland W. Herzog
View Articletitled, Synergy between rapamycin and FLT3 ligand enhances plasmacytoid dendritic cell–dependent induction of CD4<sup>+</sup>CD25<sup>+</sup>FoxP3<sup>+</sup> Treg
Supplemental data

LYMPHOID NEOPLASIA

miRs-138 and -424 control palmitoylation-dependent CD95-mediated cell death by targeting acyl protein thioesterases 1 and 2 in CLL
Valeska Berg,Marion Rusch,Nachiket Vartak,Christian Jüngst,Astrid Schauss,Herbert Waldmann,Christian Hedberg,Christian P. Pallasch,Philippe I. H. Bastiaens,Michael Hallek,Clemens-Martin Wendtner,Lukas P. Frenzel
View Articletitled, miRs-138 and -424 control palmitoylation-dependent CD95-mediated cell death by targeting acyl protein thioesterases 1 and 2 in CLL
Supplemental data
Thymic expression of a T-cell receptor targeting a tumor-associated antigen coexpressed in the thymus induces T-ALL
Yongzhi Cui,Masahiro Onozawa,Haven R. Garber,Leigh Samsel,Ziyao Wang,J. Philip McCoy,Sandra Burkett,Xiaolin Wu,Peter D. Aplan,Crystal L. Mackall
View Articletitled, Thymic expression of a T-cell receptor targeting a tumor-associated antigen coexpressed in the thymus induces T-ALL
Supplemental data
Tyrosine kinase inhibitors induce mesenchymal stem cell–mediated resistance in BCR-ABL+ acute lymphoblastic leukemia
Brief Report
Saradhi Mallampati,Xiaohong Leng,Haiqing Ma,Jianfang Zeng,June Li,Haiying Wang,Kevin Lin,Yue Lu,Yang Yang,Baohua Sun,Yun Gong,Ju-Seog Lee,Marina Konopleva,Michael Andreeff,Ralph B. Arlinghaus,Zhen Cai,Bingliang Fang,Haifa Shen,Xin Han,Cheryl F. Hirsch-Ginsberg,Xiaolian Gao,Anurag N. Paranjape,Sendurai A. Mani,Karen Clise-Dwyer,Xiaoping Sun
View Articletitled, Tyrosine kinase inhibitors induce mesenchymal stem cell–mediated resistance in BCR-ABL<sup>+</sup> acute lymphoblastic leukemia
Supplemental data

MYELOID NEOPLASIA

Functions of idh1 and its mutation in the regulation of developmental hematopoiesis in zebrafish
Xiangguo Shi,Bai-Liang He,Alvin C. H. Ma,Yuhan Guo,Yali Chi,Cheuk Him Man,Wenqing Zhang,Yiyue Zhang,Zilong Wen,Tao Cheng,Anskar Y. H. Leung
View Articletitled, Functions of idh1 and its mutation in the regulation of developmental hematopoiesis in zebrafish
Supplemental data
Downregulation of the Wnt inhibitor CXXC5 predicts a better prognosis in acute myeloid leukemia
Clinical Trials & Observations
Andrea Kühnl,Peter J. M. Valk,Mathijs A. Sanders,Adam Ivey,Robert K. Hills,Ken I. Mills,Rosemary E. Gale,Martin F. Kaiser,Richard Dillon,Melanie Joannides,Amanda Gilkes,Torsten Haferlach,Susanne Schnittger,Estelle Duprez,David C. Linch,Ruud Delwel,Bob Löwenberg,Claudia D. Baldus,Ellen Solomon,Alan K. Burnett,David Grimwade
View Articletitled, Downregulation of the Wnt inhibitor CXXC5 predicts a better prognosis in acute myeloid leukemia
Supplemental data

PLATELETS AND THROMBOPOIESIS

Pak2 restrains endomitosis during megakaryopoiesis and alters cytoskeleton organization
Rachelle E. Kosoff,Joseph E. Aslan,John C. Kostyak,Essel Dulaimi,Hoi Yee Chow,Tatiana Y. Prudnikova,Maria Radu,Satya P. Kunapuli,Owen J. T. McCarty,Jonathan Chernoff
View Articletitled, Pak2 restrains endomitosis during megakaryopoiesis and alters cytoskeleton organization
Supplemental data

THROMBOSIS AND HEMOSTASIS

von Willebrand factor propeptide and the phenotypic classification of von Willebrand disease
Clinical Trials & Observations
Yvonne V. Sanders,Dafna Groeneveld,Karina Meijer,Karin Fijnvandraat,Marjon H. Cnossen,Johanna G. van der Bom,M. Coppens,Joke de Meris,Britta A. P. Laros-van Gorkom,Eveline P. Mauser-Bunschoten,Frank W. G. Leebeek,Jeroen Eikenboom,the WiN study group
View Articletitled, von Willebrand factor propeptide and the phenotypic classification of von Willebrand disease
Supplemental data

TRANSPLANTATION

α-Mannan induces Th17-mediated pulmonary graft-versus-host disease in mice
Hidetaka Uryu,Daigo Hashimoto,Koji Kato,Eiko Hayase,Satomi Matsuoka,Reiki Ogasawara,Shuichiro Takahashi,Yoshinobu Maeda,Hiromi Iwasaki,Toshihiro Miyamoto,Shinobu Saijo,Yoichiro Iwakura,Geoffrey R. Hill,Koichi Akashi,Takanori Teshima
View Articletitled, α-Mannan induces Th17-mediated pulmonary graft-versus-host disease in mice
Supplemental data
Risk-stratified outcomes of nonmyeloablative HLA-haploidentical BMT with high-dose posttransplantation cyclophosphamide
Clinical Trials & Observations
Shannon R. McCurdy,Jennifer A. Kanakry,Margaret M. Showel,Hua-Ling Tsai,Javier Bolaños-Meade,Gary L. Rosner,Christopher G. Kanakry,Karlo Perica,Heather J. Symons,Robert A. Brodsky,Douglas E. Gladstone,Carol Ann Huff,Keith W. Pratz,Gabrielle T. Prince,Amy E. Dezern,Ivana Gojo,William H. Matsui,Ivan Borrello,Michael A. McDevitt,Lode J. Swinnen,B. Douglas Smith,Mark J. Levis,Richard F. Ambinder,Leo Luznik,Richard J. Jones,Ephraim J. Fuchs,Yvette L. Kasamon
View Articletitled, Risk-stratified outcomes of nonmyeloablative HLA-haploidentical BMT with high-dose posttransplantation cyclophosphamide
Supplemental data

BLOOD WORK

Dysplastic changes of peripheral eosinophils in acute myeloid leukemia with myelodysplastic syndrome–related features
Sunyoung Lee,John O. Mascarenhas
View Articletitled, Dysplastic changes of peripheral eosinophils in acute myeloid leukemia with myelodysplastic syndrome–related features

CORRESPONDENCE

Rising rates of acute lymphoblastic leukemia in Hispanic children: trends in incidence from 1992 to 2011
Jessica L. Barrington-Trimis,Myles Cockburn,Catherine Metayer,W. James Gauderman,Joseph Wiemels,Roberta McKean-Cowdin
View Articletitled, Rising rates of acute lymphoblastic leukemia in Hispanic children: trends in incidence from 1992 to 2011
Platelet dense granule secretion defects may obscure α-granule secretion mechanisms: evidence from Munc13-4–deficient platelets
Matthew T. Harper,Marion T. van den Bosch,Ingeborg Hers,Alastair W. Poole
View Articletitled, Platelet dense granule secretion defects may obscure α-granule secretion mechanisms: evidence from Munc13-4–deficient platelets

ERRATA

Tassara M, Döhner K, Brossart P, et al. Valproic acid in combination with all-trans retinoic acid and intensive therapy for acute myeloid leukemia in older patients. Blood. 2014;123(26):4027-4036.
View Articletitled, Tassara M, Döhner K, Brossart P, et al. Valproic acid in combination with all-trans retinoic acid and intensive therapy for acute myeloid leukemia in older patients. <em>Blood</em>. 2014;123(26):4027-4036.
All Issues

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