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Journal Articles

MARCKS affects cell motility and response to BTK inhibitors in CLL

Laura Beckmann, Valeska Berg, Clarissa Dickhut, Clare Sun, Olaf Merkel, Johannes Bloehdorn, Sandra Robrecht, Marc Seifert, Alexandra da Palma Guerreiro, Julia Claasen, Stefan Loroch, Matteo Oliverio, Chingiz Underbayev, Lauren Vaughn, Daniel Thomalla, Malte F. Hülsemann, Eugen Tausch, Kirsten Fischer, Anna Maria Fink, Barbara Eichhorst, Albert Sickmann, Clemens M. Wendtner, Stephan Stilgenbauer, Michael Hallek, Adrian Wiestner, René P. Zahedi, Lukas P. Frenzel
Journal: Blood
Blood (2021) 138 (7): 544–556.
https://doi.org/10.1182/blood.2020009165
Published: 2021
Includes: Supplemental data
Journal Articles

BIM Regulation Is BTK Dependent and Can be Targeted By Entospletinib in Ibrutinib Refractory Mutants

Laura Beckmann, MD, Valeska Berg, PhD, Clarissa Dickhut, Gunter Krause, PhD, René Zahedi, PhD, Michael Hallek, Lukas P. Frenzel, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1765.
https://doi.org/10.1182/blood-2019-127148
Published: 2019
Journal Articles

FcmR Shapes BCR Signaling in IgM-Positive Leukemia

Alexandra da Palma Guerreiro, PhD, Cornelia Dorweiler, Ismini Halmer, Olaf Merkel, Elena Maria Hartmann, MD, Valeska Berg, PhD, Nina Reinart, Günter Fingerle-Rowson, MD PhD, Gero Knittel, MSc, Christian Pallasch, MD, Andreas Rosenwald, Christian Reinhardt, MD, Clemens-Martin Wendtner, Michael Hallek, MD, Lukas P. Frenzel, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2620.
https://doi.org/10.1182/blood-2018-99-118352
Published: 2018
Journal Articles

Integrated Proteomic and Phosphoproteomic Analysis Reveal Novel Targets and Suggest Rationale for Ibrutinib Efficacy in UM-CLL

Laura Beckmann, MD, Valeska Berg, PhD, Clarissa Dickhut, Johannes Bloehdorn, MD, Jasmin Bahlo, PhD, Sandra Robrecht, PhD, Malte Hülsemann, MD, Stefan Loroch, Olaf Merkel, Kirsten Fischer, MD, Clemens-Martin Wendtner, Stephan Stilgenbauer, Albert Sickmann, PhD, Michael Hallek, René Zahedi, PhD, Lukas P. Frenzel, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 583.
https://doi.org/10.1182/blood-2018-99-118235
Published: 2018
Journal Articles

Increased Palmitoylation Modulates Cytoskeletal Regulators to Enhance CXCR4-Mediated Motility of Malignant B Cells

Andrea Haerzschel, PhD, Dunja Baatout, PhD, Valeska Berg, PhD, Manuela Paunovic, Karin Oberascher, PhD, Hubert Kerschbaum, PhD, Richard Greil, MD, Michael J. Hallek, MD, Tanja N. Hartmann, PhD, Lukas P. Frenzel, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 3988.
https://doi.org/10.1182/blood.V130.Suppl_1.3988.3988
Published: 2017
Journal Articles

Mechanisms of Venetoclax Resistance in Chronic Lymphocytic Leukemia

Lukas P. Frenzel, MD, Carmen D. Herling, MD PhD, Nima Abedpour, PhD, Jonathan Weiss, PhD, Petra Mayer, Maria Cartolano, PhD, Valeska Berg, PhD, Nadine Kutsch, MD, Paula Cramer, MD, Clemens-Martin Wendtner, MD, Thorsten Persigehl, MD, Andreas Saleh, MD, Janine Altmüller, PhD, Peter Nürnberg, PhD, Christian Pallasch, MD, Viktor Achter, PhD, Ulrich Lang, PhD, Barbara F. Eichhorst, MD, Roberta Castiglione, MD, Stephan C. Schaefer, MD, Reinhard Buettner, MD, Karl-Anton Kreuzer, MD, Hans Christian Reinhardt, MD, Michael J. Hallek, MD, Martin Peifer, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 263.
https://doi.org/10.1182/blood.V130.Suppl_1.263.263
Published: 2017
Journal Articles

APT1-Mediated Cross-Talk Between Palmitoylation and Phosphorylation Events of the BCR Pathway Sensitizes CLL Cells Towards BCR-Associated Kinase Inhibitors

Valeska Berg, PhD, Dunja Baatout, M.Sc., Clemens Wendtner, MD, Michael Hallek, Lukas P. Frenzel, MD
Journal: Blood
Blood (2016) 128 (22): 4361.
https://doi.org/10.1182/blood.V128.22.4361.4361
Published: 2016
Journal Articles

Loss of TOSO Promotes Richter's Transformation of TCL1A Driven CLL

Alexandra da Palma Guerreiro, PhD, Cornelia Dorweiler, Laurent Kintzelé, Dunja Baatout, M.Sc., Malte Huelsemann, Valeska Berg, PhD, Olaf Merkel, Nina Reinart, PhD, Guenter Fingerle-Rowson, MD PhD, Gero Knittel, Christian Pallasch, MD, Hans Christian Reinhardt, Clemens Martin Wendtner, MD, Michael Hallek, Lukas P. Frenzel, MD
Journal: Blood
Blood (2016) 128 (22): 354.
https://doi.org/10.1182/blood.V128.22.354.354
Published: 2016
Journal Articles

miRs-138 and -424 control palmitoylation-dependent CD95-mediated cell death by targeting acyl protein thioesterases 1 and 2 in CLL

Valeska Berg, Marion Rusch, Nachiket Vartak, Christian Jüngst, Astrid Schauss, Herbert Waldmann, Christian Hedberg, Christian P. Pallasch, Philippe I. H. Bastiaens, Michael Hallek, Clemens-Martin Wendtner, Lukas P. Frenzel
Journal: Blood
Blood (2015) 125 (19): 2948–2957.
https://doi.org/10.1182/blood-2014-07-586511
Published: 2015
Includes: Supplemental data
Journal Articles

Mirs-138 and -424 Control Palmitoylation-Dependent CD95-Mediated Cell Death By Targeting Acyl Protein Thioesterases 1 and 2 in Chronic Lymphocytic Leukemia

Valeska Berg, Marion Rusch, PhD, Nachiket Vartak, PhD, Christian Juengst, Astrid Schauss, Herbert Waldmann, PhD, Christian Hedberg, PhD, Christian P. Pallasch, MD, Philippe Bastiaens, PhD, Michael Hallek, MD, Clemens-Martin Wendtner, MD, Lukas P. Frenzel, MD
Journal: Blood
Blood (2014) 124 (21): 1953.
https://doi.org/10.1182/blood.V124.21.1953.1953
Published: 2014
Journal Articles

A Complex Molecular Network Controls Palmitoylation-Dependant CD95 Sensitivity Of CLL Cells

Valeska Berg, Nachiket Vartak, PhD, Rainer Claus, MD, Julia Claasen, Marion Rusch, PhD, Christian P. Pallasch, MD, Herbert Waldmann, PhD, Christopher Plass, PhD, Philippe Bastiaens, PhD, Michael Hallek, MD, Christian Hedberg, PhD, Clemens Wendtner, MD, Lukas P. Frenzel, MD
Journal: Blood
Blood (2013) 122 (21): 4148.
https://doi.org/10.1182/blood.V122.21.4148.4148
Published: 2013