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Journal Articles

IFN-λ therapy prevents severe gastrointestinal graft-versus-host disease

Blood (2021) 138 (8): 722–737.

https://doi.org/10.1182/blood.2020006375

Published: 2021

Includes: Supplemental data

Journal Articles

IL-6 dysregulation originates in dendritic cells and mediates graft-versus-host disease via classical signaling

Andrew N. Wilkinson, Karshing Chang, Rachel D. Kuns, Andrea S. Henden, Simone A. Minnie, Kathleen S. Ensbey, Andrew D. Clouston, Ping Zhang, Motoko Koyama, Juan Hidalgo, Stefan Rose-John, Antiopi Varelias, Slavica Vuckovic, Kate H. Gartlan, Geoffrey R. Hill

Blood (2019) 134 (23): 2092–2106.

https://doi.org/10.1182/blood.2019000396

Published: 2019

Includes: Supplemental data

Journal Articles

Donor T Cells Maintain Myeloma-Immune Equilibrium after Autologous Stem Cell Transplantation and Concurrent Immunotherapy Promotes Cure

Simone A Minnie, David Smith, Kate H Gartlan, PhD, Thomas S Watkins, Kate A Markey, PhD MBBS, Camille Guillerey, PhD, Rachel D Kuns, BSc, Kelly R Locke, Antiopi Varelias, PhD, Ping Zhang, Nicholas Huntington, PhD, Marta Chesi, PhD, John J Miles, PhD, Mark J Smyth, PhD, Slavica Vuckovic, PhD, Geoffrey R Hill, MD PhD

Blood (2018) 132 (Supplement 1): 2031.

https://doi.org/10.1182/blood-2018-99-118058

Published: 2018

Journal Articles

Myeloma escape after stem cell transplantation is a consequence of T-cell exhaustion and is prevented by TIGIT blockade

Simone A. Minnie, Rachel D. Kuns, Kate H. Gartlan, Ping Zhang, Andrew N. Wilkinson, Luke Samson, Camille Guillerey, Christian Engwerda, Kelli P. A. MacDonald, Mark J. Smyth, Kate A. Markey, Slavica Vuckovic, Geoffrey R. Hill

Blood (2018) 132 (16): 1675–1688.

https://doi.org/10.1182/blood-2018-01-825240

Published: 2018

Includes: Supplemental data

Journal Articles

In Vivo Expansion of Recipient DC Leads to Deletion of Donor Alloreactive CD8 + T Cells and Is an Alternative to Post-Transplant Cyclophosphamide for the Prevention of Graft-Versus-Host Disease after BMT

Kate A Markey, MBBS, PhD, Rachel D Kuns, BSc, Daniel J Browne, BSc, Kate H Gartlan, PhD, Renee J Robb, PhD, J Paulo Martins, BSc, Andrea S Henden, MBBS, Simone A Minnie, BSc, Melody Cheong, PhD, Motoko Koyama, MD PhD, Mark J Smyth, PhD, Gabrielle T Belz, PhD, Thomas Brocker, PhD, Mariapia Degli-Esposti, PhD, Steven W. Lane, MD PhD, Geoff R Hill, MD

Blood (2017) 130 (Supplement 1): 4443.

https://doi.org/10.1182/blood.V130.Suppl_1.4443.4443

Published: 2017

Journal Articles

Acute graft-versus-host disease is regulated by an IL-17–sensitive microbiome

Antiopi Varelias, Kate L. Ormerod, Mark D. Bunting, Motoko Koyama, Kate H. Gartlan, Rachel D. Kuns, Nancy Lachner, Kelly R. Locke, Chun Y. Lim, Andrea S. Henden, Ping Zhang, Andrew D. Clouston, Sumaira Z. Hasnain, Michael A. McGuckin, Bruce R. Blazar, Kelli P. A. MacDonald, Philip Hugenholtz, Geoffrey R. Hill

Blood (2017) 129 (15): 2172–2185.

https://doi.org/10.1182/blood-2016-08-732628

Published: 2017

Includes: Supplemental data

Journal Articles

GVHD prevents NK-cell–dependent leukemia and virus-specific innate immunity

Mark D. Bunting, Antiopi Varelias, Fernando Souza-Fonseca-Guimaraes, Iona S. Schuster, Katie E. Lineburg, Rachel D. Kuns, Peter Fleming, Kelly R. Locke, Nicholas D. Huntington, Bruce R. Blazar, Steven W. Lane, Siok-Keen Tey, Kelli P. A. MacDonald, Mark J. Smyth, Mariapia A. Degli-Esposti, Geoffrey R. Hill

Blood (2017) 129 (5): 630–642.

https://doi.org/10.1182/blood-2016-08-734020

Published: 2017

Includes: Supplemental data

Journal Articles

Corruption of dendritic cell antigen presentation during acute GVHD leads to regulatory T-cell failure and chronic GVHD

Lucie Leveque-El mouttie, Motoko Koyama, Laetitia Le Texier, Kate A. Markey, Melody Cheong, Rachel D. Kuns, Katie E. Lineburg, Bianca E. Teal, Kylie A. Alexander, Andrew D. Clouston, Bruce R. Blazar, Geoffrey R. Hill, Kelli P. A. MacDonald

Blood (2016) 128 (6): 794–804.

https://doi.org/10.1182/blood-2015-11-680876

Published: 2016

Includes: Supplemental data

Journal Articles

Recipient CD8 + DC Delete Alloreactive Donor CTL and Promote Leukemic Relapse after Allogeneic BMT

Kate A Markey, MBBS, PhD, Rachel D Kuns, BSc, Renee J Robb, PhD, Motoko Koyama, MDPhD, Kate Helen Gartlan, PhD, Andrea S Henden, MBBS, Simone A Minnie, B Sc, Kelli P A Macdonald, PhD, Thomas Brocker, PhD, Gabrielle T Belz, PhD, Steven W. Lane, MD, Geoff R Hill, MD

Blood (2015) 126 (23): 4279.

https://doi.org/10.1182/blood.V126.23.4279.4279

Published: 2015

Journal Articles

Hematopoeitic Stem Cells and Their Progenitors Critically Require Autophagy to Promote Early Engraftment Following Allogeneic Stem Cell Transplantation

Katie E Lineburg, BSc, Lucie Leveque-El Mouttie, PhD, Laetitia Le Texier, PhD, Bianca Teal, Rachel D Kuns, BSc, Geoffrey R Hill, MD PhD, Kelli P A MacDonald, PhD

Blood (2015) 126 (23): 34.

https://doi.org/10.1182/blood.V126.23.34.34

Published: 2015

Journal Articles

Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8 + T cells that induce GVHD without antileukemic effects

Blood (2015) 126 (13): 1609–1620.

https://doi.org/10.1182/blood-2015-01-622662

Published: 2015

Includes: Supplemental data

Journal Articles

Acute GVHD results in a severe DC defect that prevents T-cell priming and leads to fulminant cytomegalovirus disease in mice

Matthew E. Wikstrom, Peter Fleming, Rachel D. Kuns, Iona S. Schuster, Valentina Voigt, Gregory Miller, Andrew D. Clouston, Siok-Keen Tey, Christopher E. Andoniou, Geoffrey R. Hill, Mariapia A. Degli-Esposti

Blood (2015) 126 (12): 1503–1514.

https://doi.org/10.1182/blood-2015-01-622837

Published: 2015

Includes: Supplemental data

Journal Articles

Autophagy is required for stem cell mobilization by G-CSF

Lucie Leveque-El Mouttie, Therese Vu, Katie E. Lineburg, Rachel D. Kuns, Frederik O. Bagger, Bianca E. Teal, Mary Lor, Glen M. Boyle, Claudia Bruedigam, Justine D. Mintern, Geoffrey R. Hill, Kelli P. A. MacDonald, Steven W. Lane

Blood (2015) 125 (19): 2933–2936.

https://doi.org/10.1182/blood-2014-03-562660

Published: 2015

Includes: Supplemental data

Journal Articles

Lung parenchyma-derived IL-6 promotes IL-17A–dependent acute lung injury after allogeneic stem cell transplantation

Blood (2015) 125 (15): 2435–2444.

https://doi.org/10.1182/blood-2014-07-590232

Published: 2015

Includes: Supplemental data

Journal Articles

Lung Parenchyma–Derived IL-6 Induces Alloantigen Specific Th17 Differentiation Within The Lung and Idiopathic Pneumonia Syndrome After Allogeneic Stem Cell Transplantation

Blood (2013) 122 (21): 2011.

https://doi.org/10.1182/blood.V122.21.2011.2011

Published: 2013

Journal Articles

The Tc17 Population Required For Sclerodermatous Chronic Gvhd Represents a Non-Cytolytic, Pluripotent Inflammatory Effector T Cell Lineage

Kate H Gartlan, Kate A Markey, Katie E Lineburg, Antiopi Varelias, Stuart D Olver, Neil C Raffelt, Rachel D Kuns, Bianca E Teal, Mary Lor, Geoffrey R Hill, Kelli PA MacDonald

Blood (2013) 122 (21): 4475.

https://doi.org/10.1182/blood.V122.21.4475.4475

Published: 2013

Journal Articles

Autophagy Is Required For Long-Term Hematopoietic Stem Cell (HSC) Function and G-CSF-Induced HSC Mobilization

Lucie Leveque, Therese Vu, Rachel D Kuns, Bianca E Teal, Mary Lor, Katie E Lineburg, Claudia Bruedigam, Frederik Otzen Bagger, Glen Boyle, PhD, Geoffrey R Hill, Kelli P A MacDonald, PhD, Steven W Lane, MD, PhD

Blood (2013) 122 (21): 892.

https://doi.org/10.1182/blood.V122.21.892.892

Published: 2013

Journal Articles

Promoting regulation via the inhibition of DNAM-1 after transplantation

Motoko Koyama, Rachel D. Kuns, Stuart D. Olver, Katie E. Lineburg, Mary Lor, Bianca E. Teal, Neil C. Raffelt, Lucie Leveque, Christopher J. Chan, Renee J. Robb, Kate A. Markey, Kylie A. Alexander, Antiopi Varelias, Andrew D. Clouston, Mark J. Smyth, Kelli P. A. MacDonald, Geoffrey R. Hill

Blood (2013) 121 (17): 3511–3520.

https://doi.org/10.1182/blood-2012-07-444026

Published: 2013

Journal Articles

Promoting Regulation Via the Inhibition of DNAM-1 After Transplantation

Motoko Koyama, MD, PhD, Rachel D Kuns, Stuart D Olver, Katie E Lineburg, Mary Lor, Bianca E Teal, Neil C Raffelt, Lucie Leveque, Christopher J Chan, Renee J Robb, PhD, Kate A Markey, MD, PhD, Kylie A Alexander, PhD, Antiopi Varelias, PhD, Andrew D Clouston, MD, Kelli P A MacDonald, PhD, Mark J Smyth, PhD, Geoffrey R Hill, MD

Blood (2012) 120 (21): 338.

https://doi.org/10.1182/blood.V120.21.338.338

Published: 2012

Journal Articles

Identification and expansion of highly suppressive CD8 + FoxP3 + regulatory T cells after experimental allogeneic bone marrow transplantation

Renee J. Robb, Katie E. Lineburg, Rachel D. Kuns, Yana A. Wilson, Neil C. Raffelt, Stuart D. Olver, Antiopi Varelias, Kylie A. Alexander, Bianca E. Teal, Tim Sparwasser, Gunter J. Hammerling, Kate A. Markey, Motoko Koyama, Andrew D. Clouston, Christian R. Engwerda, Geoffrey R. Hill, Kelli P. A. MacDonald

Blood (2012) 119 (24): 5898–5908.

https://doi.org/10.1182/blood-2011-12-396119

Published: 2012

NARROW

IFN-λ therapy prevents severe gastrointestinal graft-versus-host disease

IL-6 dysregulation originates in dendritic cells and mediates graft-versus-host disease via classical signaling

Donor T Cells Maintain Myeloma-Immune Equilibrium after Autologous Stem Cell Transplantation and Concurrent Immunotherapy Promotes Cure

Myeloma escape after stem cell transplantation is a consequence of T-cell exhaustion and is prevented by TIGIT blockade

In Vivo Expansion of Recipient DC Leads to Deletion of Donor Alloreactive CD8 + T Cells and Is an Alternative to Post-Transplant Cyclophosphamide for the Prevention of Graft-Versus-Host Disease after BMT

Acute graft-versus-host disease is regulated by an IL-17–sensitive microbiome

GVHD prevents NK-cell–dependent leukemia and virus-specific innate immunity

Corruption of dendritic cell antigen presentation during acute GVHD leads to regulatory T-cell failure and chronic GVHD

Recipient CD8 + DC Delete Alloreactive Donor CTL and Promote Leukemic Relapse after Allogeneic BMT

Hematopoeitic Stem Cells and Their Progenitors Critically Require Autophagy to Promote Early Engraftment Following Allogeneic Stem Cell Transplantation

Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8 + T cells that induce GVHD without antileukemic effects

Acute GVHD results in a severe DC defect that prevents T-cell priming and leads to fulminant cytomegalovirus disease in mice

Autophagy is required for stem cell mobilization by G-CSF

Lung parenchyma-derived IL-6 promotes IL-17A–dependent acute lung injury after allogeneic stem cell transplantation

Lung Parenchyma–Derived IL-6 Induces Alloantigen Specific Th17 Differentiation Within The Lung and Idiopathic Pneumonia Syndrome After Allogeneic Stem Cell Transplantation

The Tc17 Population Required For Sclerodermatous Chronic Gvhd Represents a Non-Cytolytic, Pluripotent Inflammatory Effector T Cell Lineage

Autophagy Is Required For Long-Term Hematopoietic Stem Cell (HSC) Function and G-CSF-Induced HSC Mobilization

Promoting regulation via the inhibition of DNAM-1 after transplantation

Promoting Regulation Via the Inhibition of DNAM-1 After Transplantation

Identification and expansion of highly suppressive CD8 + FoxP3 + regulatory T cells after experimental allogeneic bone marrow transplantation

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American Society of Hematology

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ASH Publications

American Society of Hematology

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