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Kate H. Gartlan
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Journal Articles

IFN-λ therapy prevents severe gastrointestinal graft-versus-host disease

Andrea S. Henden, Motoko Koyama, Renee J. Robb, Adriana Forero, Rachel D. Kuns, Karshing Chang, Kathleen S. Ensbey, Antiopi Varelias, Stephen H. Kazakoff, Nicole Waddell, Andrew D. Clouston, Rabina Giri, Jakob Begun, Bruce R. Blazar, Mariapia A. Degli-Esposti, Sergei V. Kotenko, Steven W. Lane, Kate L. Bowerman, Ram Savan, Philip Hugenholtz, Kate H. Gartlan, Geoffrey R. Hill
Journal: Blood
Blood (2021) 138 (8): 722–737.
https://doi.org/10.1182/blood.2020006375
Published: 2021
Includes: Supplemental data
Journal Articles

A phase 3 double-blind study of the addition of tocilizumab vs placebo to cyclosporin/methotrexate GVHD prophylaxis

Clinical Trials & Observations
Glen A. Kennedy, Siok-Keen Tey, Luke Buizen, Antiopi Varelias, Kate H. Gartlan, Cameron Curley, Stuart D. Olver, Karshing Chang, Jason P. Butler, Ashish Misra, Elango Subramoniapillai, A. James Morton, Simon Durrant, Andrea S. Henden, John Moore, David Ritchie, David Gottlieb, Julian Cooney, Sanjoy K. Paul, Geoffrey R. Hill
Journal: Blood
Blood (2021) 137 (14): 1970–1979.
https://doi.org/10.1182/blood.2020009050
Published: 2021
Includes: Supplemental data
Journal Articles

IL-6 dysregulation originates in dendritic cells and mediates graft-versus-host disease via classical signaling

Andrew N. Wilkinson, Karshing Chang, Rachel D. Kuns, Andrea S. Henden, Simone A. Minnie, Kathleen S. Ensbey, Andrew D. Clouston, Ping Zhang, Motoko Koyama, Juan Hidalgo, Stefan Rose-John, Antiopi Varelias, Slavica Vuckovic, Kate H. Gartlan, Geoffrey R. Hill
Journal: Blood
Blood (2019) 134 (23): 2092–2106.
https://doi.org/10.1182/blood.2019000396
Published: 2019
Includes: Supplemental data
Journal Articles

Donor T Cells Maintain Myeloma-Immune Equilibrium after Autologous Stem Cell Transplantation and Concurrent Immunotherapy Promotes Cure

Simone A Minnie, David Smith, Kate H Gartlan, PhD, Thomas S Watkins, Kate A Markey, PhD MBBS, Camille Guillerey, PhD, Rachel D Kuns, BSc, Kelly R Locke, Antiopi Varelias, PhD, Ping Zhang, Nicholas Huntington, PhD, Marta Chesi, PhD, John J Miles, PhD, Mark J Smyth, PhD, Slavica Vuckovic, PhD, Geoffrey R Hill, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2031.
https://doi.org/10.1182/blood-2018-99-118058
Published: 2018
Journal Articles

Myeloma escape after stem cell transplantation is a consequence of T-cell exhaustion and is prevented by TIGIT blockade

Simone A. Minnie, Rachel D. Kuns, Kate H. Gartlan, Ping Zhang, Andrew N. Wilkinson, Luke Samson, Camille Guillerey, Christian Engwerda, Kelli P. A. MacDonald, Mark J. Smyth, Kate A. Markey, Slavica Vuckovic, Geoffrey R. Hill
Journal: Blood
Blood (2018) 132 (16): 1675–1688.
https://doi.org/10.1182/blood-2018-01-825240
Published: 2018
Includes: Supplemental data
Journal Articles

In Vivo Expansion of Recipient DC Leads to Deletion of Donor Alloreactive CD8 + T Cells and Is an Alternative to Post-Transplant Cyclophosphamide for the Prevention of Graft-Versus-Host Disease after BMT

Kate A Markey, MBBS, PhD, Rachel D Kuns, BSc, Daniel J Browne, BSc, Kate H Gartlan, PhD, Renee J Robb, PhD, J Paulo Martins, BSc, Andrea S Henden, MBBS, Simone A Minnie, BSc, Melody Cheong, PhD, Motoko Koyama, MD PhD, Mark J Smyth, PhD, Gabrielle T Belz, PhD, Thomas Brocker, PhD, Mariapia Degli-Esposti, PhD, Steven W. Lane, MD PhD, Geoff R Hill, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4443.
https://doi.org/10.1182/blood.V130.Suppl_1.4443.4443
Published: 2017
Journal Articles

A Critical Role for Donor-Derived IL-22 in Cutaneous Chronic Gvhd

Kate H Gartlan, PhD, Hemamalini Bommiasamy, PhD, Katelyn Paz, Andrew Wilkinson, Mary Owen, Dawn Reichenbach, PhD, Tatjana Banovic, PhD MD, Kimberly Wehner, Faith Buchanan, Antiopi Varelias, PhD, Rachel Kuns, Karshing Chang, Yuri Fedoriw, MD, Thomas C. Shea, MD, James M. Coghill, Jr., MD, Michael Zaiken, Maximilian Plank, PhD, Paul Foster, Andrew Clouston, Bruce Blazar, MD, Jonathan S Serody, MD, Geoffrey R Hill, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 69.
https://doi.org/10.1182/blood.V130.Suppl_1.69.69
Published: 2017
Journal Articles

Acute graft-versus-host disease is regulated by an IL-17–sensitive microbiome

Antiopi Varelias, Kate L. Ormerod, Mark D. Bunting, Motoko Koyama, Kate H. Gartlan, Rachel D. Kuns, Nancy Lachner, Kelly R. Locke, Chun Y. Lim, Andrea S. Henden, Ping Zhang, Andrew D. Clouston, Sumaira Z. Hasnain, Michael A. McGuckin, Bruce R. Blazar, Kelli P. A. MacDonald, Philip Hugenholtz, Geoffrey R. Hill
Journal: Blood
Blood (2017) 129 (15): 2172–2185.
https://doi.org/10.1182/blood-2016-08-732628
Published: 2017
Includes: Supplemental data
Journal Articles

Tc17 cells are a proinflammatory, plastic lineage of pathogenic CD8 + T cells that induce GVHD without antileukemic effects

Kate H. Gartlan, Kate A. Markey, Antiopi Varelias, Mark D. Bunting, Motoko Koyama, Rachel D. Kuns, Neil C. Raffelt, Stuart D. Olver, Katie E. Lineburg, Melody Cheong, Bianca E. Teal, Mary Lor, Iain Comerford, Michele W. L. Teng, Mark J. Smyth, James McCluskey, Jamie Rossjohn, Brigitta Stockinger, Glen M. Boyle, Steven W. Lane, Andrew D. Clouston, Shaun R. McColl, Kelli P. A. MacDonald, Geoffrey R. Hill
Journal: Blood
Blood (2015) 126 (13): 1609–1620.
https://doi.org/10.1182/blood-2015-01-622662
Published: 2015
Includes: Supplemental data
Journal Articles

Lung parenchyma-derived IL-6 promotes IL-17A–dependent acute lung injury after allogeneic stem cell transplantation

Antiopi Varelias, Kate H. Gartlan, Ellen Kreijveld, Stuart D. Olver, Mary Lor, Rachel D. Kuns, Katie E. Lineburg, Bianca E. Teal, Neil C. Raffelt, Melody Cheong, Kylie A. Alexander, Motoko Koyama, Kate A. Markey, Elise Sturgeon, Justine Leach, Pavan Reddy, Glen A. Kennedy, Gregory A. Yanik, Bruce R. Blazar, Siok-Keen Tey, Andrew D. Clouston, Kelli P. A. MacDonald, Kenneth R. Cooke, Geoffrey R. Hill
Journal: Blood
Blood (2015) 125 (15): 2435–2444.
https://doi.org/10.1182/blood-2014-07-590232
Published: 2015
Includes: Supplemental data
Journal Articles

The Tc17 Population Required For Sclerodermatous Chronic Gvhd Represents a Non-Cytolytic, Pluripotent Inflammatory Effector T Cell Lineage

Kate H Gartlan, Kate A Markey, Katie E Lineburg, Antiopi Varelias, Stuart D Olver, Neil C Raffelt, Rachel D Kuns, Bianca E Teal, Mary Lor, Geoffrey R Hill, Kelli PA MacDonald
Journal: Blood
Blood (2013) 122 (21): 4475.
https://doi.org/10.1182/blood.V122.21.4475.4475
Published: 2013
Journal Articles

Lung Parenchyma–Derived IL-6 Induces Alloantigen Specific Th17 Differentiation Within The Lung and Idiopathic Pneumonia Syndrome After Allogeneic Stem Cell Transplantation

Antiopi Varelias, Kate H Gartlan, Stuart D Olver, Katie E Lineburg, Rachel D Kuns, Mary Lor, Bianca E Teal, Melody Cheong, Motoko Koyama, Kate A Markey, Kylie Alexander, Alison Budelsky, Elise Sturgeon, Justine Leach, Judy Avery, Glen A Kennedy, Siok- Tey, Andrew D Clouston, Kelli PA MacDonald, Geoff R Hill
Journal: Blood
Blood (2013) 122 (21): 2011.
https://doi.org/10.1182/blood.V122.21.2011.2011
Published: 2013