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Simone A. Minnie
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Journal Articles

Cross-Talk between Leukemic Blasts and T Cells Drives Targetable T Cell Dysfunction in the AML Tumor Microenvironment

Susan DeWolf, Nicholas Ceglia, Matthew Zatzman, Brianna Gipson, Yuval Elhanati, Zoe Katsamakis, Hannah Lees, Kenyon Weis, Gustavo Yepes, Barbara Oliveira, Ana Figueiredo Longhini, Natalie Grier Smith, Katherine Nichols, Eliyahu Havasov, Karen Zhao, Brigita Meskauskaite, Ignas Masilionis, Alexander M. Lewis, Maria Adriana Cuibus, M. Kazim Pajwani, Simone A Minnie, Ronan Chaligne, Andri Leo L Lemarquis, Aaron D. Goldberg, Katharine C. Hsu, Eytan M. Stein, Benjamin D. Greenbaum, Omar Abdel-Wahab, Sohrab P. Shah, Marcel R.M. van den Brink
Journal: Blood
Blood (2024) 144 (Supplement 1): 637.
https://doi.org/10.1182/blood-2024-194037
Published: 2024
Journal Articles

Donor XCR1 + and CD11b + Dendritic Cells Determine the Severity of Th1 and Th17-Dependent Acute Gvhd within the Gastrointestinal Tract

Motoko Koyama, Shuichiro Takahashi, Takayuki Inoue, Kathleen S Ensbey, Samuel R. W. Legg, Tomoko Sekiguchi, Ethan Nelson, Nicole S Nemychenkov, Tanvi Joshi, Simone A Minnie, Albert C Yeh, Julie R Boiko, Ping Zhang, Mark B Headley, Jisun Paik, John K Amory, Geoffrey R. Hill
Journal: Blood
Blood (2024) 144 (Supplement 1): 905.
https://doi.org/10.1182/blood-2024-209473
Published: 2024
Journal Articles

Regulatory T cells suppress myeloma-specific immunity during autologous stem cell mobilization and transplantation

Shuichiro Takahashi, Simone A. Minnie, Kathleen S. Ensbey, Christine R. Schmidt, Tomoko Sekiguchi, Samuel R. W. Legg, Ping Zhang, Motoko Koyama, Stuart D. Olver, Alika D. Collinge, Sara Keshmiri, Melissa L. Comstock, Antiopi Varelias, Damian J. Green, Geoffrey R. Hill
Journal: Blood
Blood (2024) 143 (16): 1656–1669.
https://doi.org/10.1182/blood.2023022000
Published: 2024
Includes: Supplemental data
Journal Articles

Microbiota-Specific T Cells Contribute to Graft-Versus-Host Disease after Allogeneic Stem Cell Transplantation

Albert C Yeh, Motoko Koyama, Olivia Waltner, Simone A Minnie, Julie Boiko, Tamer B Shabaneh, Shuichiro Takahashi, Ping Zhang, Kathleen Ensbey, Christine Schmidt, Samuel Legg, Tomoko Sekiguchi, Ethan Nelson, Shruti Bhise, Andrew Stevens, Tracy A Goodpaster, Saranya R. Chakka, Scott N. Furlan, Kate A. Markey, Marie Bleakley, Charles O Elson, III, Geoffrey R Hill
Journal: Blood
Blood (2023) 142 (Supplement 1): 345.
https://doi.org/10.1182/blood-2023-178773
Published: 2023
Journal Articles

Regulatory T Cell Depletion during Stem Cell Mobilization Enhances Anti-Myeloma Immunity after Experimental Autologous Stem Cell Transplantation

Shuichiro Takahashi, Simone A Minnie, Samuel RW Legg, Christine R Schmidt, Kathleen S Ensbey, Damian J. Green, Geoffrey R Hill
Journal: Blood
Blood (2022) 140 (Supplement 1): 2086–2087.
https://doi.org/10.1182/blood-2022-168117
Published: 2022
Journal Articles

The Combination of Anti-Tigit and Lenalidomide Promotes Synergistic Myeloma-Specific Immunity after ASCT

Simone A Minnie, Nicole S Nemychenkov, Kathleen S Ensbey, Christine R Schmidt, Gregory Driessens, Gabriela Campoy, Shuichiro Takahashi, Leona A. Holmberg, Geoffrey R Hill
Journal: Blood
Blood (2021) 138 (Supplement 1): 328.
https://doi.org/10.1182/blood-2021-154087
Published: 2021
Journal Articles

Non-Genetic Determinants of Clonotypic T Cell Expansion Following Allogeneic Stem Cell Transplant

Albert Yeh, Motoko Koyama, Simone A Minnie, Julie Boiko, Kathleen S Ensbey, Christine R Schmidt, Sam Legg, Gabriela Campoy, Ethan Nelson, Phil Bradley, Geoff R. Hill
Journal: Blood
Blood (2021) 138 (Supplement 1): 646.
https://doi.org/10.1182/blood-2021-146026
Published: 2021
Journal Articles

The IL-2/IL-15 Mimetic NL-201 Prevents Myeloma Relapse after ASCT By Expanding Highly Cytolytic T Cells in the Bone Marrow That Are Resistant to Exhaustion

Simone A Minnie, Nicole S Nemychenkov, Shuichiro Takahashi, Christine R Schmidt, Samuel RW Legg, Kathleen S Ensbey, Geoffrey R Hill
Journal: Blood
Blood (2021) 138 (Supplement 1): 1609.
https://doi.org/10.1182/blood-2021-153095
Published: 2021
Journal Articles

IL-6 dysregulation originates in dendritic cells and mediates graft-versus-host disease via classical signaling

Andrew N. Wilkinson, Karshing Chang, Rachel D. Kuns, Andrea S. Henden, Simone A. Minnie, Kathleen S. Ensbey, Andrew D. Clouston, Ping Zhang, Motoko Koyama, Juan Hidalgo, Stefan Rose-John, Antiopi Varelias, Slavica Vuckovic, Kate H. Gartlan, Geoffrey R. Hill
Journal: Blood
Blood (2019) 134 (23): 2092–2106.
https://doi.org/10.1182/blood.2019000396
Published: 2019
Includes: Supplemental data
Journal Articles

Donor T Cells Maintain Myeloma-Immune Equilibrium after Autologous Stem Cell Transplantation and Concurrent Immunotherapy Promotes Cure

Simone A Minnie, David Smith, Kate H Gartlan, PhD, Thomas S Watkins, Kate A Markey, PhD MBBS, Camille Guillerey, PhD, Rachel D Kuns, BSc, Kelly R Locke, Antiopi Varelias, PhD, Ping Zhang, Nicholas Huntington, PhD, Marta Chesi, PhD, John J Miles, PhD, Mark J Smyth, PhD, Slavica Vuckovic, PhD, Geoffrey R Hill, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 2031.
https://doi.org/10.1182/blood-2018-99-118058
Published: 2018
Journal Articles

Myeloma escape after stem cell transplantation is a consequence of T-cell exhaustion and is prevented by TIGIT blockade

Simone A. Minnie, Rachel D. Kuns, Kate H. Gartlan, Ping Zhang, Andrew N. Wilkinson, Luke Samson, Camille Guillerey, Christian Engwerda, Kelli P. A. MacDonald, Mark J. Smyth, Kate A. Markey, Slavica Vuckovic, Geoffrey R. Hill
Journal: Blood
Blood (2018) 132 (16): 1675–1688.
https://doi.org/10.1182/blood-2018-01-825240
Published: 2018
Includes: Supplemental data
Journal Articles

TIGIT immune checkpoint blockade restores CD8 + T-cell immunity against multiple myeloma

Brief Report
Camille Guillerey, Heidi Harjunpää, Nadège Carrié, Sahar Kassem, Tricia Teo, Kim Miles, Sophie Krumeich, Marianne Weulersse, Marine Cuisinier, Kimberley Stannard, Yuan Yu, Simone A. Minnie, Geoffrey R. Hill, William C. Dougall, Hervé Avet-Loiseau, Michele W. L. Teng, Kyohei Nakamura, Ludovic Martinet, Mark J. Smyth
Journal: Blood
Blood (2018) 132 (16): 1689–1694.
https://doi.org/10.1182/blood-2018-01-825265
Published: 2018
Journal Articles

In Vivo Expansion of Recipient DC Leads to Deletion of Donor Alloreactive CD8 + T Cells and Is an Alternative to Post-Transplant Cyclophosphamide for the Prevention of Graft-Versus-Host Disease after BMT

Kate A Markey, MBBS, PhD, Rachel D Kuns, BSc, Daniel J Browne, BSc, Kate H Gartlan, PhD, Renee J Robb, PhD, J Paulo Martins, BSc, Andrea S Henden, MBBS, Simone A Minnie, BSc, Melody Cheong, PhD, Motoko Koyama, MD PhD, Mark J Smyth, PhD, Gabrielle T Belz, PhD, Thomas Brocker, PhD, Mariapia Degli-Esposti, PhD, Steven W. Lane, MD PhD, Geoff R Hill, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 4443.
https://doi.org/10.1182/blood.V130.Suppl_1.4443.4443
Published: 2017
Journal Articles

Recipient CD8 + DC Delete Alloreactive Donor CTL and Promote Leukemic Relapse after Allogeneic BMT

Kate A Markey, MBBS, PhD, Rachel D Kuns, BSc, Renee J Robb, PhD, Motoko Koyama, MDPhD, Kate Helen Gartlan, PhD, Andrea S Henden, MBBS, Simone A Minnie, B Sc, Kelli P A Macdonald, PhD, Thomas Brocker, PhD, Gabrielle T Belz, PhD, Steven W. Lane, MD, Geoff R Hill, MD
Journal: Blood
Blood (2015) 126 (23): 4279.
https://doi.org/10.1182/blood.V126.23.4279.4279
Published: 2015