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Tomoko Sekiguchi
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Journal Articles

CSF-1R inhibition and lenalidomide synergize to promote myeloma control after autologous stem cell transplantation

Free
Simone Minnie, Rachael Adams, Kathleen Ensbey, Christine Schmidt, Melissa Comstock, Justina Lyons, Samuel Legg, Tomoko Sekiguchi, Nicole Nemychenkov, Julie Boiko, Motoko Koyama, Andrew Spencer, Damian Green, Geoff Hill
Journal: Blood
Blood (2025) 146 (Supplement 1): 689.
https://doi.org/10.1182/blood-2025-689
Published: 2025
Journal Articles

IFNγ-driven MHC class II expression by intestinal epithelial cells dictates local cytolytic Th1 cell differentiation and intestinal stem cell loss

Free
Motoko Koyama, Albert Yeh, Kathleen Ensbey, Shruti Bhise, Iona Schuster, Samuel Legg, Ethan Nelson, Tomoko Sekiguchi, Nicole Nemychenkov, Shuichiro Takahashi, Ping Zhang, Simone Minnie, Francoise Haeseleer, Daniel Hippe, Mariapia Degli-Esposti, Scott Furlan, Geoff Hill
Journal: Blood
Blood (2025) 146 (Supplement 1): 159.
https://doi.org/10.1182/blood-2025-159
Published: 2025
Journal Articles

Multiplex detection of gastrointestinal microbiota using short probes in graft vs. host disease

Free
Albert Yeh, Annalyssa Long, David Sierra, Paul Kong, Kathleen Ensbey, Samuel Legg, Tomoko Sekiguchi, Tomas Bencomo, Anna Elz, Neelendu Dey, Armin Rashidi, Kate Markey, David Fredricks, David Hockenbery, Geoff Hill
Journal: Blood
Blood (2025) 146 (Supplement 1): 2311.
https://doi.org/10.1182/blood-2025-2311
Published: 2025
Journal Articles

Donor XCR1 + and CD11b + Dendritic Cells Determine the Severity of Th1 and Th17-Dependent Acute Gvhd within the Gastrointestinal Tract

Free
Motoko Koyama, Shuichiro Takahashi, Takayuki Inoue, Kathleen S Ensbey, Samuel R. W. Legg, Tomoko Sekiguchi, Ethan Nelson, Nicole S Nemychenkov, Tanvi Joshi, Simone A Minnie, Albert C Yeh, Julie R Boiko, Ping Zhang, Mark B Headley, Jisun Paik, John K Amory, Geoffrey R. Hill
Journal: Blood
Blood (2024) 144 (Supplement 1): 905.
https://doi.org/10.1182/blood-2024-209473
Published: 2024
Journal Articles

Cytokines associated with organ manifestations in chronic graft-versus-host disease

Free
Stephanie J. Lee, Ningxin Ma, Timothy Randolph, Carrie L. Kitko, Corey S. Cutler, Najla El Jurdi, George Chen, Betty K. Hamilton, Joseph A. Pidala, Paul A Carpenter, Sally Arai, Lynn Onstad, Sophie Paczesny, Tomoko Sekiguchi, Motoko Koyama, Geoffrey R. Hill
Journal: Blood
Blood (2024) 144 (Supplement 1): 4902.
https://doi.org/10.1182/blood-2024-203743
Published: 2024
Journal Articles

GVHD targets organoid-forming bile duct stem cells in a TGF-β–dependent manner

Free
Yuta Hasegawa, Daigo Hashimoto, Zixuan Zhang, Toru Miyajima, Yumika Saito, Wenyu Li, Ryo Kikuchi, Hajime Senjo, Tomoko Sekiguchi, Takahiro Tateno, Xuanzhong Chen, Emi Yokoyama, Shuichiro Takahashi, Hiroyuki Ohigashi, Takahide Ara, Eiko Hayase, Isao Yokota, Takanori Teshima
Journal: Blood
Blood (2024) 144 (8): 904–913.
https://doi.org/10.1182/blood.2023023060
Published: 2024
Includes: Supplemental data
Journal Articles

Regulatory T cells suppress myeloma-specific immunity during autologous stem cell mobilization and transplantation

Free
Shuichiro Takahashi, Simone A. Minnie, Kathleen S. Ensbey, Christine R. Schmidt, Tomoko Sekiguchi, Samuel R. W. Legg, Ping Zhang, Motoko Koyama, Stuart D. Olver, Alika D. Collinge, Sara Keshmiri, Melissa L. Comstock, Antiopi Varelias, Damian J. Green, Geoffrey R. Hill
Journal: Blood
Blood (2024) 143 (16): 1656–1669.
https://doi.org/10.1182/blood.2023022000
Published: 2024
Includes: Supplemental data
Journal Articles

Microbiota-Specific T Cells Contribute to Graft-Versus-Host Disease after Allogeneic Stem Cell Transplantation

Free
Albert C Yeh, Motoko Koyama, Olivia Waltner, Simone A Minnie, Julie Boiko, Tamer B Shabaneh, Shuichiro Takahashi, Ping Zhang, Kathleen Ensbey, Christine Schmidt, Samuel Legg, Tomoko Sekiguchi, Ethan Nelson, Shruti Bhise, Andrew Stevens, Tracy A Goodpaster, Saranya R. Chakka, Scott N. Furlan, Kate A. Markey, Marie Bleakley, Charles O Elson, III, Geoffrey R Hill
Journal: Blood
Blood (2023) 142 (Supplement 1): 345.
https://doi.org/10.1182/blood-2023-178773
Published: 2023
Journal Articles

Gvhd Targets Organoid-Forming Biliary Epithelial Stem Cells Via a TGF-β-Dependent Manner

Free
Yuta Hasegawa, Daigo Hashimoto, Ryo Kikuchi, Zixuan Zhang, Hajime Senjo, Tomoko Sekiguchi, Eiko Hayase, Takahiro Tateno, Emi Yokoyama, Shuichiro Takahashi, Xuanzhong Chen, Kazuki Yoneda, Hiroyuki Ohigashi, Takahide Ara, Takanori Teshima
Journal: Blood
Blood (2021) 138 (Supplement 1): 90.
https://doi.org/10.1182/blood-2021-149061
Published: 2021