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Journal Articles

p21-activated kinase 2 regulates HSPC cytoskeleton, migration, and homing via CDC42 activation and interaction with β-Pix

Pavankumar N. G. Reddy, Maria Radu, Ke Xu, Jenna Wood, Chad E. Harris, Jonathan Chernoff, David A. Williams
Journal: Blood
Blood (2016) 127 (16): 1967–1975.
https://doi.org/10.1182/blood-2016-01-693572
Published: 2016
Journal Articles

Pak2 restrains endomitosis during megakaryopoiesis and alters cytoskeleton organization

Rachelle E. Kosoff, Joseph E. Aslan, John C. Kostyak, Essel Dulaimi, Hoi Yee Chow, Tatiana Y. Prudnikova, Maria Radu, Satya P. Kunapuli, Owen J. T. McCarty, Jonathan Chernoff
Journal: Blood
Blood (2015) 125 (19): 2995–3005.
https://doi.org/10.1182/blood-2014-10-604504
Published: 2015
Includes: Supplemental data
Journal Articles

Kinase Activity Of Pak2, An Effector Of Rac/CDC42 and Its Interaction With β-PIX Is Required For Murine Hematopoietic Stem Cell Shape, F-Actin Formation, Directional Migration In Vitro and For HSPC Homing To Bone Marrow In Vivo

Pavankumar N.G. Reddy, PhD, Jenna Wood, Chad E Harris, Ke Xu, Meaghan McGuinness, Maria Radu, MD PhD, Rachelle Kosoff, Jonathan Chernoff, MD, PhD, David A. Williams, MD
Journal: Blood
Blood (2013) 122 (21): 2419.
https://doi.org/10.1182/blood.V122.21.2419.2419
Published: 2013
Journal Articles

The Rac GTPase effector p21-activated kinase is essential for hematopoietic stem/progenitor cell migration and engraftment

Adrienne M. Dorrance, Serena De Vita, Maria Radu, Pavankumar N. G. Reddy, Meaghan K. McGuinness, Chad E. Harris, Ronald Mathieu, Steven W. Lane, Rachelle Kosoff, Michael D. Milsom, Jonathan Chernoff, David A. Williams
Journal: Blood
Blood (2013) 121 (13): 2474–2482.
https://doi.org/10.1182/blood-2012-10-460709
Published: 2013
Includes: Multimedia, Supplemental data