Corien L. Eckhardt,for the INSIGHT Study Group,Alice S. van Velzen,for the INSIGHT Study Group,Marjolein Peters,for the INSIGHT Study Group,Jan Astermark,for the INSIGHT Study Group,Paul P. Brons,for the INSIGHT Study Group,Giancarlo Castaman,for the INSIGHT Study Group,Marjon H. Cnossen,for the INSIGHT Study Group,Natasja Dors,for the INSIGHT Study Group,Carmen Escuriola-Ettingshausen,for the INSIGHT Study Group,Karly Hamulyak,for the INSIGHT Study Group,Daniel P. Hart,for the INSIGHT Study Group,Charles R. M. Hay,for the INSIGHT Study Group,Saturnino Haya,for the INSIGHT Study Group,Waander L. van Heerde,for the INSIGHT Study Group,Cedric Hermans,for the INSIGHT Study Group,Margareta Holmström,for the INSIGHT Study Group,Victor Jimenez-Yuste,for the INSIGHT Study Group,Russell D. Keenan,for the INSIGHT Study Group,Robert Klamroth,for the INSIGHT Study Group,Britta A. P. Laros-van Gorkom,for the INSIGHT Study Group,Frank W. G. Leebeek,for the INSIGHT Study Group,Ri Liesner,for the INSIGHT Study Group,Anne Mäkipernaa,for the INSIGHT Study Group,Christoph Male,for the INSIGHT Study Group,Evelien Mauser-Bunschoten,for the INSIGHT Study Group,Maria G. Mazzucconi,for the INSIGHT Study Group,Simon McRae,for the INSIGHT Study Group,Karina Meijer,for the INSIGHT Study Group,Michael Mitchell,for the INSIGHT Study Group,Massimo Morfini,for the INSIGHT Study Group,Marten Nijziel,for the INSIGHT Study Group,Johannes Oldenburg,for the INSIGHT Study Group,Kathelijne Peerlinck,for the INSIGHT Study Group,Pia Petrini,for the INSIGHT Study Group,Helena Platokouki,for the INSIGHT Study Group,Sylvia E. Reitter-Pfoertner,for the INSIGHT Study Group,Elena Santagostino,for the INSIGHT Study Group,Piercarla Schinco,for the INSIGHT Study Group,Frans J. Smiers,for the INSIGHT Study Group,Berthold Siegmund,for the INSIGHT Study Group,Annarita Tagliaferri,for the INSIGHT Study Group,Thynn T. Yee,for the INSIGHT Study Group,Pieter Willem Kamphuisen,for the INSIGHT Study Group,Johanna G. van der Bom,for the INSIGHT Study Group,Karin Fijnvandraat,for the INSIGHT Study Group

View Articletitled, Factor VIII gene (F8) mutation and risk of inhibitor development in nonsevere hemophilia A

Supplemental data

TRANSPLANTATION

HLA class II upregulation during viral infection leads to HLA-DP–directed graft-versus-host disease after CD4+ donor lymphocyte infusion

Sanja Stevanović,Cornelis A. M. van Bergen,Simone A. P. van Luxemburg-Heijs,Boris van der Zouwen,Ekaterina S. Jordanova,Alwine B. Kruisselbrink,Marian van de Meent,Jessica C. Harskamp,Frans H. J. Claas,Erik W. A. Marijt,Jaap Jan Zwaginga,Constantijn J. M. Halkes,Inge Jedema,Marieke Griffioen,J. H. Frederik Falkenburg

View Articletitled, HLA class II upregulation during viral infection leads to HLA-DP–directed graft-versus-host disease after CD4+ donor lymphocyte infusion

Supplemental data

Impact of donor source on hematopoietic cell transplantation outcomes for patients with myelodysplastic syndromes (MDS)

Wael Saber,Corey S. Cutler,Ryotaro Nakamura,Mei-Jie Zhang,Ehab Atallah,J. Douglas Rizzo,Richard T. Maziarz,Jorge Cortes,Matt E. Kalaycio,Mary M. Horowitz

View Articletitled, Impact of donor source on hematopoietic cell transplantation outcomes for patients with myelodysplastic syndromes (MDS)

Supplemental data

CORRESPONDENCE

In vivo evidence insufficient to conclude that “KIR/HLA incompatibility between sexual partners confers protection against HIV-1 transmission”

Carolyn E. Behrendt,John A. Zaia

View Articletitled, In vivo evidence insufficient to conclude that “KIR/HLA incompatibility between sexual partners confers protection against HIV-1 transmission”

Response: KIR/HLA incompatibility in HIV-1 transmission and importance of the ‘missing self’ model

Wim Jennes,Sonja Verheyden,Julie W. Mertens,Makhtar Camara,Moussa Seydi,Tandakha N. Dieye,Souleymane Mboup,Christian Demanet,Luc Kestens

View Articletitled, Response: KIR/HLA incompatibility in HIV-1 transmission and importance of the ‘missing self’ model

Molecular classification of mature aggressive B-cell lymphoma using digital multiplexed gene expression on formalin-fixed paraffin-embedded biopsy specimens

Neus Masqué-Soler,Monika Szczepanowski,Christian W. Kohler,Rainer Spang,Wolfram Klapper

View Articletitled, Molecular classification of mature aggressive B-cell lymphoma using digital multiplexed gene expression on formalin-fixed paraffin-embedded biopsy specimens

Supplemental data

ANKRD26-related thrombocytopenia and myeloid malignancies

Patrizia Noris,Remi Favier,Marie-Christine Alessi,Amy E. Geddis,Shinji Kunishima,Paula G. Heller,Paola Giordano,Karen Y. Niederhoffer,James B. Bussel,Gian Marco Podda,Nicola Vianelli,Rogier Kersseboom,Alessandro Pecci,Chiara Gnan,Caterina Marconi,Anne Auvrignon,William Cohen,Jennifer C. Yu,Akihiro Iguchi,Allison Miller Imahiyerobo,Francoise Boehlen,Dorsaf Ghalloussi,Daniela De Rocco,Pamela Magini,Elisa Civaschi,Ginevra Biino,Marco Seri,Anna Savoia,Carlo L. Balduini

View Articletitled, ANKRD26-related thrombocytopenia and myeloid malignancies

Plasma hepcidin of Ethiopian highlanders with steady-state hypoxia

Erika L. Lundgrin,Allison J. Janocha,Carl D. Koch,Amha Gebremedhin,Anna Di Rienzo,Gorka Alkorta-Aranburu,Gary M. Brittenham,Serpil C. Erzurum,Cynthia M. Beall

View Articletitled, Plasma hepcidin of Ethiopian highlanders with steady-state hypoxia

Supplemental data

Fcγ receptor IIB gene polymorphism in adult Japanese patients with primary immune thrombocytopenia

Takashi Satoh,Koji Miyazaki,Asako Shimohira,Naoki Amano,Yuka Okazaki,Tetsuya Nishimoto,Tohru Akahoshi,Shinichi Munekata,Yuhsaku Kanoh,Yasuo Ikeda,Masaaki Higashihara,Shinichiro Takahashi,Masataka Kuwana

View Articletitled, Fcγ receptor IIB gene polymorphism in adult Japanese patients with primary immune thrombocytopenia

Supplemental data

Cover Image

Cover Image

Multicolor immunofluorescent staining for CD3 (clone PS1, IgG2a + IgG2a ALEXA 546) (red), CD8 (clone 4B11, IgG2b + IgGb ALEXA 647) (blue), and HLA class II (clone CR3/43, IgG1 + IgG1 ALEXA 488) (green) was performed on colonic biopsy from patient-2 obtained at the time of GVHD diagnosis after CD4+ DLI. Double CD3+CD8+ cells (purple) were defined as CD8+ T-cells, whereas CD3+CD8- expressing cells (red) were defined as CD4+ T-cells. Images were captured with a confocal laser scanning microscope (LSM510, Zeiss, Sliedrecht, The Netherlands) (×200 magnification) (supplemental Methods). See the article by Stevanović et al on page 1963.
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