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The achievement of an early complete cytogenetic response is a major determinant for outcome in patients with early chronic phase chronic myeloid leukemia treated with tyrosine kinase inhibitors
Health-related quality of life in chronic myeloid leukemia patients receiving long-term therapy with imatinib compared with the general population
Prognostic implications of the IDH1 synonymous SNP rs11554137 in pediatric and adult AML: a report from the Children's Oncology Group and SWOG
Safety and efficacy of bosutinib (SKI-606) in chronic phase Philadelphia chromosome–positive chronic myeloid leukemia patients with resistance or intolerance to imatinib
Outcome according to cytogenetic abnormalities and DNA ploidy in myeloma patients receiving short induction with weekly bortezomib followed by maintenance
The utility of plasma vascular endothelial growth factor levels in the diagnosis and follow-up of patients with POEMS syndrome
Twenty-one cases of blastic plasmacytoid dendritic cell neoplasm: focus on biallelic locus 9p21.3 deletion
Chemoimmunotherapy for hemophagocytic lymphohistiocytosis: long-term results of the HLH-94 treatment protocol
Genome-wide ChIP-Seq reveals a dramatic shift in the binding of the transcription factor erythroid Kruppel-like factor during erythrocyte differentiation
Incidence of a first thromboembolic event in asymptomatic carriers of high-risk antiphospholipid antibody profile: a multicenter prospective study
A 2-step approach to myeloablative haploidentical stem cell transplantation: a phase 1/2 trial performed with optimized T-cell dosing
Issue Archive
October 27 2011
In this Issue
Table of Contents
Inside Blood
Plenary Paper
Review Article
Personalized therapy in multiple myeloma according to patient age and vulnerability: a report of the European Myeloma Network (EMN)
Antonio Palumbo,Sara Bringhen,Heinz Ludwig,Meletios A. Dimopoulos,Joan Bladé,Maria V. Mateos,Laura Rosiñol,Mario Boccadoro,Michele Cavo,Henk Lokhorst,Sonja Zweegman,Evangelos Terpos,Faith Davies,Christoph Driessen,Peter Gimsing,Martin Gramatzki,Roman Hàjek,Hans E. Johnsen,Fernando Leal Da Costa,Orhan Sezer,Andrew Spencer,Meral Beksac,Gareth Morgan,Hermann Einsele,Jesus F. San Miguel,Pieter Sonneveld
How I Treat
Clinical Trials and Observations
The achievement of an early complete cytogenetic response is a major determinant for outcome in patients with early chronic phase chronic myeloid leukemia treated with tyrosine kinase inhibitors
CME
Elias Jabbour,Hagop Kantarjian,Susan O'Brien,Jenny Shan,Alfonso Quintas-Cardama,Stefan Faderl,Guillermo Garcia-Manero,Farhad Ravandi,Mary Beth Rios,Jorge Cortes
Health-related quality of life in chronic myeloid leukemia patients receiving long-term therapy with imatinib compared with the general population
Clinical Trials & Observations
Fabio Efficace,Michele Baccarani,Massimo Breccia,Giuliana Alimena,Gianantonio Rosti,Francesco Cottone,Giorgio Lambertenghi Deliliers,Claudia Baratè,Antonella Russo Rossi,Giuseppe Fioritoni,Luigia Luciano,Diamante Turri,Bruno Martino,Francesco Di Raimondo,Melissa Dabusti,Micaela Bergamaschi,Pietro Leoni,Maria Pina Simula,Luciano Levato,Stefano Ulisciani,Dino Veneri,Simona Sica,Alessandro Rambaldi,Marco Vignetti,Franco Mandelli,for GIMEMA
Prognostic implications of the IDH1 synonymous SNP rs11554137 in pediatric and adult AML: a report from the Children's Oncology Group and SWOG
Clinical Trials & Observations
Phoenix A. Ho,Kenneth J. Kopecky,Todd A. Alonzo,Robert B. Gerbing,Kristen L. Miller,Julia Kuhn,Rong Zeng,Rhonda E. Ries,Susana C. Raimondi,Betsy A. Hirsch,Vivian Oehler,Craig A. Hurwitz,Janet L. Franklin,Alan S. Gamis,Stephen H. Petersdorf,Jeanne E. Anderson,John E. Godwin,Gregory H. Reaman,Cheryl L. Willman,Irwin D. Bernstein,Jerald P. Radich,Frederick R. Appelbaum,Derek L. Stirewalt,Soheil Meshinchi
Safety and efficacy of bosutinib (SKI-606) in chronic phase Philadelphia chromosome–positive chronic myeloid leukemia patients with resistance or intolerance to imatinib
Clinical Trials & Observations
Jorge E. Cortes,Hagop M. Kantarjian,Tim H. Brümmendorf,Dong-Wook Kim,Anna G. Turkina,Zhi-Xiang Shen,Ricardo Pasquini,H. Jean Khoury,Steven Arkin,Angela Volkert,Nadine Besson,Richat Abbas,Junyuan Wang,Eric Leip,Carlo Gambacorti-Passerini
Gene Therapy
Hematopoiesis and Stem Cells
Immunobiology
Subtle differences in CTL cytotoxicity determine susceptibility to hemophagocytic lymphohistiocytosis in mice and humans with Chediak-Higashi syndrome
Birthe Jessen,Andrea Maul-Pavicic,Heike Ufheil,Thomas Vraetz,Anselm Enders,Kai Lehmberg,Alfred Längler,Ute Gross-Wieltsch,Ali Bay,Zuhre Kaya,Yenan T. Bryceson,Ewa Koscielniak,Sherif Badawy,Graham Davies,Markus Hufnagel,Annette Schmitt-Graeff,Peter Aichele,Udo zur Stadt,Klaus Schwarz,Stephan Ehl
Lymphoid Neoplasia
Outcome according to cytogenetic abnormalities and DNA ploidy in myeloma patients receiving short induction with weekly bortezomib followed by maintenance
Clinical Trials & Observations
María-Victoria Mateos,Norma C. Gutiérrez,María-Luisa Martín-Ramos,Bruno Paiva,María-Angeles Montalbán,Albert Oriol,Joaquín Martínez-López,Ana-Isabel Teruel,Enrique Bengoechea,Alejandro Martín,Joaquín Díaz-Mediavilla,Felipe de Arriba,Luis Palomera,José-Mariano Hernández,Anna Sureda,Joan Bargay,Francisco-Javier Peñalver,Josep-Maria Ribera,María-Luisa Martín-Mateos,Manuela Fernández,Ramón García-Sanz,María-Belén Vidriales,Joan Bladé,Juan-José Lahuerta,Jesús F. San Miguel
The cooperating mutation or “second hit” determines the immunologic visibility toward MYC-induced murine lymphomas
Christian Schuster,Angelika Berger,Maria A. Hoelzl,Eva M. Putz,Anna Frenzel,Olivia Simma,Nadine Moritz,Andrea Hoelbl,Boris Kovacic,Michael Freissmuth,Mathias Müller,Andreas Villunger,Leonard Müllauer,Ana-Iris Schmatz,Berthold Streubel,Edit Porpaczy,Ulrich Jäger,Dagmar Stoiber,Veronika Sexl
Cell of origin strongly influences genetic selection in a mouse model of T-ALL
Katherine E. Berquam-Vrieze,Kishore Nannapaneni,Benjamin T. Brett,Linda Holmfeldt,Jing Ma,Oksana Zagorodna,Nancy A. Jenkins,Neal G. Copeland,David K. Meyerholz,C. Michael Knudson,Charles G. Mullighan,Todd E. Scheetz,Adam J. Dupuy
The utility of plasma vascular endothelial growth factor levels in the diagnosis and follow-up of patients with POEMS syndrome
Brief Report
Anita D'Souza,Suzanne R. Hayman,Francis Buadi,Michelle Mauermann,Martha Q. Lacy,Morie A. Gertz,Robert A. Kyle,Shaji Kumar,Philip R. Greipp,John A. Lust,Stephen J. Russell,Steven Zeldenrust,David Dingli,Thomas E. Witzig,S. Vincent Rajkumar,Angela Dispenzieri
Myeloid Neoplasia
Twenty-one cases of blastic plasmacytoid dendritic cell neoplasm: focus on biallelic locus 9p21.3 deletion
Brief Report
Marco Lucioni,Francesca Novara,Giacomo Fiandrino,Roberta Riboni,Daniele Fanoni,Mariarosa Arra,Luigia Venegoni,Marta Nicola,Elena Dallera,Luca Arcaini,Francesco Onida,Pamela Vezzoli,Erica Travaglino,Emanuela Boveri,Orsetta Zuffardi,Marco Paulli,Emilio Berti
Coordinate loss of a microRNA and protein-coding gene cooperate in the pathogenesis of 5q− syndrome
Madhu S. Kumar,Anupama Narla,Atsushi Nonami,Ann Mullally,Nadya Dimitrova,Brian Ball,J. Randall McAuley,Luke Poveromo,Jeffrey L. Kutok,Naomi Galili,Azra Raza,Eyal Attar,D. Gary Gilliland,Tyler Jacks,Benjamin L. Ebert
Phagocytes, Granulocytes, and Myelopoiesis
Chemoimmunotherapy for hemophagocytic lymphohistiocytosis: long-term results of the HLH-94 treatment protocol
Clinical Trials & Observations
Helena Trottestam,AnnaCarin Horne,Maurizio Aricò,R. Maarten Egeler,Alexandra H. Filipovich,Helmut Gadner,Shinsaku Imashuku,Stephan Ladisch,David Webb,Gritta Janka,Jan-Inge Henter,for the Histiocyte Society
Red Cells, Iron, and Erythropoiesis
Genome-wide ChIP-Seq reveals a dramatic shift in the binding of the transcription factor erythroid Kruppel-like factor during erythrocyte differentiation
e-blood
Andre M. Pilon,Subramanian S. Ajay,Swathi Ashok Kumar,Laurie A. Steiner,Praveen F. Cherukuri,Stephen Wincovitch,Stacie M. Anderson,NISC Comparative Sequencing Center,James C. Mullikin,Patrick G. Gallagher,Ross C. Hardison,Elliott H. Margulies,David M. Bodine
Thrombosis and Hemostasis
Incidence of a first thromboembolic event in asymptomatic carriers of high-risk antiphospholipid antibody profile: a multicenter prospective study
Clinical Trials & Observations
Vittorio Pengo,Amelia Ruffatti,Cristina Legnani,Sophie Testa,Tiziana Fierro,Francesco Marongiu,Valeria De Micheli,Paolo Gresele,Marta Tonello,Angelo Ghirarduzzi,Elisa Bison,Gentian Denas,Alessandra Banzato,Seena Padayattil Jose,Sabino Iliceto
Transplantation
A 2-step approach to myeloablative haploidentical stem cell transplantation: a phase 1/2 trial performed with optimized T-cell dosing
Clinical Trials & Observations
Dolores Grosso,Matthew Carabasi,Joanne Filicko-O'Hara,Margaret Kasner,John L. Wagner,Beth Colombe,Patricia Cornett Farley,William O'Hara,Phyllis Flomenberg,Maria Werner-Wasik,Janet Brunner,Bijoyesh Mookerjee,Terry Hyslop,Mark Weiss,Neal Flomenberg
Vascular Biology
Other Departments
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Cover Image
Cover Image
![issue cover]()
To connect with the host vasculature, implanted endothelial cells (green) wrap around existing vessels (brown), express MMPs (small dots), modify existing wall structure, and replace the underlying host ECs in a process of “wrapping-and-tapping” anastomosis. Illustration by Lance Munn. See the article by Cheng et al on page 4740.
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