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Randomized study of induction therapy comparing standard-dose idarubicin with high-dose daunorubicin in adult patients with previously untreated acute myeloid leukemia: the JALSG AML201 Study
A randomized comparison of 4 courses of standard-dose multiagent chemotherapy versus 3 courses of high-dose cytarabine alone in postremission therapy for acute myeloid leukemia in adults: the JALSG AML201 Study
Prognostic impact, concurrent genetic mutations, and gene expression features of AML with CEBPA mutations in a cohort of 1182 cytogenetically normal AML patients: further evidence for CEBPA double mutant AML as a distinctive disease entity
The sensing of poorly deformable red blood cells by the human spleen can be mimicked in vitro
Issue Archive
February 24 2011
In this Issue
Table of Contents
Inside blood
Perspectives
Review Article
How I Treat
Clinical Trials and Observations
Randomized study of induction therapy comparing standard-dose idarubicin with high-dose daunorubicin in adult patients with previously untreated acute myeloid leukemia: the JALSG AML201 Study
Clinical Trials & Observations
Shigeki Ohtake,Shuichi Miyawaki,Hiroyuki Fujita,Hitoshi Kiyoi,Katsuji Shinagawa,Noriko Usui,Hirokazu Okumura,Koichi Miyamura,Chiaki Nakaseko,Yasushi Miyazaki,Atsushi Fujieda,Tadashi Nagai,Takahisa Yamane,Masafumi Taniwaki,Masatomo Takahashi,Fumiharu Yagasaki,Yukihiko Kimura,Norio Asou,Hisashi Sakamaki,Hiroshi Handa,Sumihisa Honda,Kazunori Ohnishi,Tomoki Naoe,Ryuzo Ohno
A randomized comparison of 4 courses of standard-dose multiagent chemotherapy versus 3 courses of high-dose cytarabine alone in postremission therapy for acute myeloid leukemia in adults: the JALSG AML201 Study
Clinical Trials & Observations
Shuichi Miyawaki,Shigeki Ohtake,Shin Fujisawa,Hitoshi Kiyoi,Katsuji Shinagawa,Noriko Usui,Toru Sakura,Koichi Miyamura,Chiaki Nakaseko,Yasushi Miyazaki,Atsushi Fujieda,Tadashi Nagai,Takahisa Yamane,Masafumi Taniwaki,Masatomo Takahashi,Fumiharu Yagasaki,Yukihiko Kimura,Norio Asou,Hisashi Sakamaki,Hiroshi Handa,Sumihisa Honda,Kazunori Ohnishi,Tomoki Naoe,Ryuzo Ohno
Prognostic impact, concurrent genetic mutations, and gene expression features of AML with CEBPA mutations in a cohort of 1182 cytogenetically normal AML patients: further evidence for CEBPA double mutant AML as a distinctive disease entity
Clinical Trials & Observations
Erdogan Taskesen,Lars Bullinger,Andrea Corbacioglu,Mathijs A. Sanders,Claudia A. J. Erpelinck,Bas J. Wouters,Sonja C. van der Poel-van de Luytgaarde,Frederik Damm,Jürgen Krauter,Arnold Ganser,Richard F. Schlenk,Bob Löwenberg,Ruud Delwel,Hartmut Döhner,Peter J. M. Valk,Konstanze Döhner
Hematopoiesis and Stem Cells
Immunobiology
Lymphoid Neoplasia
The host genetic background of DNA repair mechanisms is an independent predictor of survival in diffuse large B-cell lymphoma
Davide Rossi,Silvia Rasi,Alice Di Rocco,Alberto Fabbri,Francesco Forconi,Annunziata Gloghini,Alessio Bruscaggin,Silvia Franceschetti,Marco Fangazio,Lorenzo De Paoli,Riccardo Bruna,Daniela Capello,Annalisa Chiappella,Chiara Lobetti Bodoni,Manuela Giachelia,Maria Chiara Tisi,Enrico M. Pogliani,Francesco Lauria,Marco Ladetto,Stefan Hohaus,Maurizio Martelli,Umberto Vitolo,Antonino Carbone,Robin Foà,Gianluca Gaidano
High-throughput mutation profiling of CTCL samples reveals KRAS and NRAS mutations sensitizing tumors toward inhibition of the RAS/RAF/MEK signaling cascade
Michael K. Kießling,Patrick A. Oberholzer,Chandrani Mondal,Maria B. Karpova,Marie C. Zipser,William M. Lin,Michael Girardi,Laura E. MacConaill,Sarah M. Kehoe,Charlie Hatton,Lars E. French,Levi A. Garraway,Gernot Polier,Dorothee Süss,Claus-Detlev Klemke,Peter H. Krammer,Karsten Gülow,Reinhard Dummer
Somatic mutations at EZH2 Y641 act dominantly through a mechanism of selectively altered PRC2 catalytic activity, to increase H3K27 trimethylation
Damian B. Yap,Justin Chu,Tobias Berg,Matthieu Schapira,S.-W. Grace Cheng,Annie Moradian,Ryan D. Morin,Andrew J. Mungall,Barbara Meissner,Merrill Boyle,Victor E. Marquez,Marco A. Marra,Randy D. Gascoyne,R. Keith Humphries,Cheryl H. Arrowsmith,Gregg B. Morin,Samuel A. J. R. Aparicio
Myeloid Neoplasia
Platelets and Thrombopoiesis
Red Cells, Iron, and Erythropoiesis
The sensing of poorly deformable red blood cells by the human spleen can be mimicked in vitro
e-blood
Guillaume Deplaine,Innocent Safeukui,Fakhri Jeddi,François Lacoste,Valentine Brousse,Sylvie Perrot,Sylvestre Biligui,Micheline Guillotte,Corinne Guitton,Safi Dokmak,Béatrice Aussilhou,Alain Sauvanet,Dominique Cazals Hatem,François Paye,Marc Thellier,Dominique Mazier,Geneviève Milon,Narla Mohandas,Odile Mercereau-Puijalon,Peter H. David,Pierre A. Buffet
Thrombosis and Hemostasis
Transplantation
Vascular Biology
Dentin matrix protein 1 induces membrane expression of VE-cadherin on endothelial cells and inhibits VEGF-induced angiogenesis by blocking VEGFR-2 phosphorylation
Sophie Pirotte,Virginie Lamour,Vincent Lambert,Maria-Luz Alvarez Gonzalez,Sandra Ormenese,Agnès Noël,Denis Mottet,Vincent Castronovo,Akeila Bellahcène
Other Departments
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Cover Image
Cover Image
![issue cover]()
Fibronectin fibrillogenesis is a cell-mediated matrix assembly process. The image shows type I collagen-dependent assembly of soluble fluorescein isothiocyanate (FITC)–labeled fibronectin (green) into a fibrillar matrix in a spread CD61-positive (red) human cord blood–derived megakaryocyte. Nuclei were stained with Hoechst 33288 (blue). See the article by Malara et al on page 2476.
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