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Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 study
Molecular remission is an independent predictor of clinical outcome in patients with mantle cell lymphoma after combined immunochemotherapy: a European MCL intergroup study
High-dose cyclophosphamide as single-agent, short-course prophylaxis of graft-versus-host disease
X-linked thrombocytopenia (XLT) due to WAS mutations: clinical characteristics, long-term outcome, and treatment options
Issue Archive
April 22 2010
In this Issue
Table of Contents
INSIDE BLOOD
PLENARY PAPERS
BCR-ABL enhances differentiation of long-term repopulating hematopoietic stem cells
Mirle Schemionek,Christian Elling,Ulrich Steidl,Nicole Bäumer,Ashley Hamilton,Tilmann Spieker,Joachim R. Göthert,Martin Stehling,Amy Wagers,Claudia S. Huettner,Daniel G. Tenen,Lara Tickenbrock,Wolfgang E. Berdel,Hubert Serve,Tessa L. Holyoake,Carsten Müller-Tidow,Steffen Koschmieder
REVIEW ARTICLES
CLINICAL TRIALS AND OBSERVATIONS
Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 study
CME
Valentino Conter,Claus R. Bartram,Maria Grazia Valsecchi,André Schrauder,Renate Panzer-Grümayer,Anja Möricke,Maurizio Aricò,Martin Zimmermann,Georg Mann,Giulio De Rossi,Martin Stanulla,Franco Locatelli,Giuseppe Basso,Felix Niggli,Elena Barisone,Günter Henze,Wolf-Dieter Ludwig,Oskar A. Haas,Giovanni Cazzaniga,Rolf Koehler,Daniela Silvestri,Jutta Bradtke,Rosanna Parasole,Rita Beier,Jacques J. M. van Dongen,Andrea Biondi,Martin Schrappe
Molecular remission is an independent predictor of clinical outcome in patients with mantle cell lymphoma after combined immunochemotherapy: a European MCL intergroup study
Clinical Trials & Observations
Christiane Pott,Eva Hoster,Marie-Helene Delfau-Larue,Kheira Beldjord,Sebastian Böttcher,Vahid Asnafi,Anne Plonquet,Reiner Siebert,Evelyne Callet-Bauchu,Niels Andersen,Jacques J. M. van Dongen,Wolfram Klapper,Françoise Berger,Vincent Ribrag,Achiel L. van Hoof,Marek Trneny,Jan Walewski,Peter Dreger,Michael Unterhalt,Wolfgang Hiddemann,Michael Kneba,Hanneke C. Kluin-Nelemans,Olivier Hermine,Elizabeth Macintyre,Martin Dreyling
High-dose cyclophosphamide as single-agent, short-course prophylaxis of graft-versus-host disease
Clinical Trials & Observations
Leo Luznik,Javier Bolaños-Meade,Marianna Zahurak,Allen R. Chen,B. Douglas Smith,Robert Brodsky,Carol Ann Huff,Ivan Borrello,William Matsui,Jonathan D. Powell,Yvette Kasamon,Steven N. Goodman,Allan Hess,Hyam I. Levitsky,Richard F. Ambinder,Richard J. Jones,Ephraim J. Fuchs
X-linked thrombocytopenia (XLT) due to WAS mutations: clinical characteristics, long-term outcome, and treatment options
Clinical Trials & Observations
Michael H. Albert,Tanja C. Bittner,Shigeaki Nonoyama,Lucia Dora Notarangelo,Siobhan Burns,Kohsuke Imai,Teresa Espanol,Anders Fasth,Isabelle Pellier,Gabriele Strauss,Tomohiro Morio,Benjamin Gathmann,Jeroen G. Noordzij,Cristina Fillat,Manfred Hoenig,Michaela Nathrath,Alfons Meindl,Philipp Pagel,Uwe Wintergerst,Alain Fischer,Adrian J. Thrasher,Bernd H. Belohradsky,Hans D. Ochs
HEMATOPOIESIS AND STEM CELLS
IMMUNOBIOLOGY
LYMPHOID NEOPLASIA
High-throughput cell transplantation establishes that tumor-initiating cells are abundant in zebrafish T-cell acute lymphoblastic leukemia
Alexandra C. H. Smith,Aubrey R. Raimondi,Chris D. Salthouse,Myron S. Ignatius,Jessica S. Blackburn,Igor V. Mizgirev,Narie Y. Storer,Jill L. O. de Jong,Aye T. Chen,Yi Zhou,Sergei Revskoy,Leonard I. Zon,David M. Langenau
Correlation of the autoantibody response to the ALK oncoantigen in pediatric anaplastic lymphoma kinase–positive anaplastic large cell lymphoma with tumor dissemination and relapse risk
Kamel Ait-Tahar,Christine Damm-Welk,Birgit Burkhardt,Martin Zimmermann,Wolfram Klapper,Alfred Reiter,Karen Pulford,Wilhelm Woessmann
MYELOID NEOPLASIA
PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS
PLATELETS AND THROMBOPOIESIS
RED CELLS, IRON, AND ERYTHROPOIESIS
Comparison of 3 Tfr2-deficient murine models suggests distinct functions for Tfr2-α and Tfr2-β isoforms in different tissues
Antonella Roetto,Ferdinando Di Cunto,Rosa Maria Pellegrino,Emilio Hirsch,Ornella Azzolino,Alessandro Bondi,Ilaria Defilippi,Sonia Carturan,Barbara Miniscalco,Fulvio Riondato,Daniela Cilloni,Lorenzo Silengo,Fiorella Altruda,Clara Camaschella,Giuseppe Saglio
TRANSPLANTATION
VASCULAR BIOLOGY
CORRESPONDENCE
Once- versus twice-weekly bortezomib induction therapy with CyBorD in newly diagnosed multiple myeloma
Craig B. Reeder,Donna E. Reece,Vishal Kukreti,Christine Chen,Suzanne Trudel,Kristina Laumann,Joseph Hentz,Nicholas A. Pirooz,Jesus G. Piza,Rodger Tiedemann,Joseph R. Mikhael,Peter L. Bergsagel,Jose F. Leis,Rafael Fonseca,Alexander K. Stewart
OTHER DEPARTMENTS
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Cover Image
Cover Image
![issue cover]()
One fish, two fish, red fish, blue fish: adult transgenic zebrafish (Danio rerio) expressing fluorescent proteins in the muscle are superimposed over GFP-labeled T-cell acute lymphoblastic leukemia (T-ALL) cells from diseased animals. Zebrafish are a powerful genetic model of leukemia and have now been used in conjunction with syngeneic zebrafish lines and high-throughput cell transplantation approaches to show that leukemia-initiating cells are abundant in T-ALL. See the article by Smith et al on page 3296. Artwork and photography by David Langenau and Aubrey Raimondi.
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