1-12 of 12
David M. Langenau
Close
Sort by
Journal Articles

Therapeutic targeting of LCK tyrosine kinase and mTOR signaling in T-cell acute lymphoblastic leukemia

Saara Laukkanen, Alexandra Veloso, Chuan Yan, Laura Oksa, Eric J. Alpert, Daniel Do, Noora Hyvärinen, Karin McCarthy, Abhinav Adhikari, Qiqi Yang, Sowmya Iyer, Sara P. Garcia, Annukka Pello, Tanja Ruokoranta, Sanni Moisio, Sadiksha Adhikari, Jeffrey A. Yoder, Kayleigh Gallagher, Lauren Whelton, James R. Allen, Alex H. Jin, Siebe Loontiens, Merja Heinäniemi, Michelle Kelliher, Caroline A. Heckman, Olli Lohi, David M. Langenau
Journal: Blood
Blood (2022) 140 (17): 1891–1906.
https://doi.org/10.1182/blood.2021015106
Published: 2022
Includes: Supplemental data
Journal Articles

Redirecting T-Cells Against AML in a Multidimensional Targeting Space Using T-Cell Engaging Antibody Circuits (TEAC)

Eleanor Minogue, BSc, David Millar, PhD, Yan Chuan, PhD, Songfa Zhang, MD PhD, Korneel Grauwet, PhD, Mei Guo, Adam Langenbucher, Cyril H Benes, James Heather, PhD, Jeremy Minshull, PhD, Michael S. Lawrence, PhD, Rupa Narayan, David M. Langenau, PhD, Timothy A. Graubert, MD, Mark Cobbold
Journal: Blood
Blood (2019) 134 (Supplement_1): 2653.
https://doi.org/10.1182/blood-2019-127634
Published: 2019
Journal Articles

Thymocyte Selection-Associated High-Mobility Group Box Protein (TOX) Induces Genomic Instability in T-Cell Acute Lymphoblastic Leukemia

Riadh Lobbardi, PhD, Jordan Pinder, PhD, Barbara Martinez-Pastor, PhD, Jessica S Blackburn, PhD, Nouran Abdelfattah, Deborah Toiber, PhD, Manon De Waard, John M. Asara, PhD, Raul Mostoslavsky, MDPhD, Graham Dellaire, PhD, David M. Langenau, PhD
Journal: Blood
Blood (2014) 124 (21): 475.
https://doi.org/10.1182/blood.V124.21.475.475
Published: 2014
Journal Articles

Pten regulates zebrafish hematopoiesis

David M. Langenau
Journal: Blood
Blood (2014) 123 (2): 149–150.
https://doi.org/10.1182/blood-2013-11-536136
Published: 2014
Journal Articles

The TLE1 Tumor Suppressor Regulates Myc Induced Leukemogenesis

David Sweetser, M.D., Ph.D., Selvi Ramasamy, PhD, Jessica S Blackburn, PhD, David M. Langenau, PhD
Journal: Blood
Blood (2011) 118 (21): 2473.
https://doi.org/10.1182/blood.V118.21.2473.2473
Published: 2011
Journal Articles

Notch Expression Expands the Pre-Malignant Pool of T-Cell Acute Lymphoblastic Leukemia Clones without Affecting Self-Renewal

Jessica S Blackburn, PhD, Sali Liu, BS, David M. Langenau, PhD
Journal: Blood
Blood (2010) 116 (21): 3161.
https://doi.org/10.1182/blood.V116.21.3161.3161
Published: 2010
Journal Articles

High-throughput cell transplantation establishes that tumor-initiating cells are abundant in zebrafish T-cell acute lymphoblastic leukemia

Alexandra C. H. Smith, Aubrey R. Raimondi, Chris D. Salthouse, Myron S. Ignatius, Jessica S. Blackburn, Igor V. Mizgirev, Narie Y. Storer, Jill L. O. de Jong, Aye T. Chen, Yi Zhou, Sergei Revskoy, Leonard I. Zon, David M. Langenau
Journal: Blood
Blood (2010) 115 (16): 3296–3303.
https://doi.org/10.1182/blood-2009-10-246488
Published: 2010
Includes: Multimedia, Supplemental data
Journal Articles

Bcl2 Accelerates Onset but Not Progression of MYC-Induced T-Cell Leukemia in Transgenic Zebrafish.

Hui Feng, PhD, MD, David M. Langenau, Ph.D., Jennifer A. Kilgore, B.S., Andre Quinkertz, Ph.D., Cicely A. Jette, Ph.D., Donna S. Neuberg, Sc.D., Jose A. Campos-Ortega, Ph.D., John P. Kanki, Ph.D., Thomas Look, M.D.
Journal: Blood
Blood (2006) 108 (11): 1829.
https://doi.org/10.1182/blood.V108.11.1829.1829
Published: 2006
Journal Articles

Inducible hkRASG12D Expression in Zebrafish Hematopoietic Cells Leads to Myeloproliferative Disease.

Xiuning Le, David M. Langenau, Ph.D., Matthew D. Keefe, Jeffery L. Kutok, M.D. Ph.D., Leonard I. Zon, M.D.
Journal: Blood
Blood (2006) 108 (11): 2691.
https://doi.org/10.1182/blood.V108.11.2691.2691
Published: 2006
Journal Articles

Suppression of apoptosis by bcl-2 overexpression in lymphoid cells of transgenic zebrafish

David M. Langenau, Cicely Jette, Stephane Berghmans, Teresa Palomero, John P. Kanki, Jeffery L. Kutok, A. Thomas Look
Journal: Blood
Blood (2005) 105 (8): 3278–3285.
https://doi.org/10.1182/blood-2004-08-3073
Published: 2005
Includes: Supplemental data
Journal Articles

Effects of lethal irradiation in zebrafish and rescue by hematopoietic cell transplantation

David Traver, Alissa Winzeler, Howard M. Stern, Elizabeth A. Mayhall, David M. Langenau, Jeffrey L. Kutok, A. Thomas Look, Leonard I. Zon
Journal: Blood
Blood (2004) 104 (5): 1298–1305.
https://doi.org/10.1182/blood-2004-01-0100
Published: 2004
Includes: Multimedia, Supplemental data
Journal Articles

Myelopoiesis in the zebrafish, Danio rerio

Carolyn M. Bennett, John P. Kanki, Jennifer Rhodes, Ting X. Liu, Barry H. Paw, Mark W. Kieran, David M. Langenau, Anne Delahaye-Brown, Leonard I. Zon, Mark D. Fleming, A. Thomas Look
Journal: Blood
Blood (2001) 98 (3): 643–651.
https://doi.org/10.1182/blood.V98.3.643
Published: 2001