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Journal Articles

MYB deficiency leads to myeloid neoplasia too

Thomas J. Gonda

Blood (2023) 141 (15): 1786–1787.

https://doi.org/10.1182/blood.2022019533

Published: 2023

Journal Articles

Childhood acute myeloid leukemia shows a high level of germline predisposition

Blood (2021) 138 (22): 2293–2298.

https://doi.org/10.1182/blood.2021012666

Published: 2021

Includes: Supplemental data

Journal Articles

Rare Variants Affecting the Fanconi Anaemia DNA Repair Genes Associate with Increased Risk for AML

Kyaw Ze Ya Maung, BSc, Paul Leo, PhD, Anna L Brown, PhD, Mahmoud A Bassal, Bsc, BCompSc, Debora A. Casolari, PhD, Adam Ewing, B.A & PhD, Emma Duncan, PhD, Sarah C Bray, PhD, Evgeny Glazov, PhD, Luen Bik To, MBBS, FRACP, FRCPA, PhD, Russell Saal, MMSc, BSMedTech, Ian D Lewis, MBBS, PhD FRACP, FRCPA, Devinder S Gill, MBChB FRCPath MRCP, Paula Marlton, MBBS, FRACP, FRCPA, James X Gray, MD PhD, Thomas J Gonda, PhD, Richard D'Andrea, PhD

Blood (2016) 128 (22): 41.

https://doi.org/10.1182/blood.V128.22.41.41

Published: 2016

Journal Articles

Metabolic Profiling of Adult Acute Myeloid Leukemia (AML)

Blood (2016) 128 (22): 1684.

https://doi.org/10.1182/blood.V128.22.1684.1684

Published: 2016

Journal Articles

Rare and Common Germline Variants Contribute to Occurrence of Myelodysplastic Syndrome

Blood (2015) 126 (23): 1644.

https://doi.org/10.1182/blood.V126.23.1644.1644

Published: 2015

Journal Articles

Vascular Niche E-Selectin Protects Acute Myeloid Leukaemia Stem Cells from Chemotherapy

Ingrid G Winkler, PhD, Valerie Barbier, Diwakar R Pattabiraman, PhD, Thomas J Gonda, PhD, John L. Magnani, PhD, Jean-Pierre Levesque, PhD

Blood (2014) 124 (21): 620.

https://doi.org/10.1182/blood.V124.21.620.620

Published: 2014

Journal Articles

Whole Exome Sequencing of Acute Myeloid Leukaemia Patients Identifies Somatic and Germline Mutations in Fanconi Anaemia Genes

Kyaw Zeya Maung, BSc, James X Gray, MD PhD, Paul J Leo, PhD, Mahmoud Bassal, BSc, Anna L Brown, PhD, Sarah C Bray, PhD, Ing Soo Tiong, MBChB, Chung H Kok, PhD, Andrew Deans, PhD, Mhairi Marshall, PhD, Brooke Gardiner, PhD, Evgeny A Glazov, PhD, Paula Marlton, MBBS, Devinder Gill, MD, Luen Bik To, MBBS, PhD, Ian D Lewis, MBBS, PhD, Richard J D'Andrea, PhD, Thomas J Gonda, PhD

Blood (2014) 124 (21): 698.

https://doi.org/10.1182/blood.V124.21.698.698

Published: 2014

Journal Articles

An ENU Mutagenesis Screen of FLT3-ITD Knock-in Mice Identifies Novel Gene Mutations That Lead to an Exacerbated Myeloproliferative Neoplasm

Anna L Brown, PhD, Teresa Sadras, PhD, Grant A Engler, BSc (Hons), Robert Tunningley, PhD, Jennifer Kofler, BSc, Paul J Leo, PhD, Jesse Cheah, BSc, Adrienne Laskowski, BSc, Ann Frazier, PhD, David Stroud, PhD, Michael Ryan, PhD, David Thorburn, PhDFHGSA FFSc(RCPA), D Gary Gilliland, MDPhD, Ian D Lewis, MBBS, PhD, Thomas J Gonda, PhD, Richard J D'Andrea, PhD

Blood (2014) 124 (21): 3591.

https://doi.org/10.1182/blood.V124.21.3591.3591

Published: 2014

Journal Articles

Interaction of c-Myb with p300 is required for the induction of acute myeloid leukemia (AML) by human AML oncogenes

Diwakar R. Pattabiraman, Crystal McGirr, Konstantin Shakhbazov, Valerie Barbier, Keerthana Krishnan, Pamela Mukhopadhyay, Paula Hawthorne, Ann Trezise, Jianmin Ding, Sean M. Grimmond, Peter Papathanasiou, Warren S. Alexander, Andrew C. Perkins, Jean-Pierre Levesque, Ingrid G. Winkler, Thomas J. Gonda

Blood (2014) 123 (17): 2682–2690.

https://doi.org/10.1182/blood-2012-02-413187

Published: 2014

Includes: Supplemental data

Journal Articles

Interaction of c-Myb with p300 Is Required for the Induction of Acute Myeloid Leukemia by Human AML Oncogenes, and Represents a Potential Therapeutic Target.

Diwakar R Pattabiraman, PhD, Konstantin Shakhbazov, PhD, Valerie Barbier, Crystal McGirr, BSc (Hons), Keerthana Krishnan, BSc (Hons), Pamela Mukhopadhyay, PhD, Paula Hawthorne, PhD, Ann Trezise, PhD, Sean Grimmond, PhD, Peter Papathanasiou, Andrew C. Perkins, MBBS, PhD, FRACP, FRCPA, Jean-Pierre Levesque, PhD, Warren S. Alexander, Ingrid G Winkler, PhD, Thomas J Gonda, PhD

Blood (2012) 120 (21): 2402.

https://doi.org/10.1182/blood.V120.21.2402.2402

Published: 2012

Journal Articles

A recessive screen for genes regulating hematopoietic stem cells

Peter Papathanasiou, Robert Tunningley, Diwakar R. Pattabiraman, Ping Ye, Thomas J. Gonda, Belinda Whittle, Adam E. Hamilton, Simon O. Cridland, Rohan Lourie, Andrew C. Perkins

Blood (2010) 116 (26): 5849–5858.

https://doi.org/10.1182/blood-2010-04-269951

Published: 2010

Includes: Supplemental data

Journal Articles

Alternative modes of GM-CSF receptor activation revealed using activated mutants of the common β-subunit

Michelle Perugini, Anna L. Brown, Diana G. Salerno, Grant W. Booker, Cvetan Stojkoski, Timothy R. Hercus, Angel F. Lopez, Margaret L. Hibbs, Thomas J. Gonda, Richard J. D'Andrea

Blood (2010) 115 (16): 3346–3353.

https://doi.org/10.1182/blood-2009-08-235846

Published: 2010

Includes: Supplemental data

Journal Articles

A Recessive Embryonic Screen for Genes Regulating Hematopoietic Stem Cell and Blood Cell Generation and Function.

Peter Papathanasiou, BSc, PhD, Robert Tunningley, B, Appl, Sci, Diwakar Ram Pattabiraman, M, Phil, Ping Ye, BSc, Thomas J Gonda, PhD, Andrew Charles Perkins, MB, BS, PhD, FRACP, FRCPA

Blood (2009) 114 (22): 2527.

https://doi.org/10.1182/blood.V114.22.2527.2527

Published: 2009

Journal Articles

Identification of Novel MYB Target Genes

Liang Zhao, PhD, Faisal Al- Owaidi, MSc, Diwakar R Pattabiraman, MPhil, Emily Verrier, BSc, Anna Tsykin, PhD, Gregory J. Goodall, PhD, Paul Leo, PhD, Thomas J Gonda, PhD

Blood (2008) 112 (11): 3580.

https://doi.org/10.1182/blood.V112.11.3580.3580

Published: 2008

Journal Articles

Constitutive mutants of the GM-CSF receptor reveal multiple pathways leading to myeloid cell survival, proliferation, and granulocyte-macrophage differentiation

Anna L. Brown, Michelle Peters, Richard J. D'Andrea, Thomas J. Gonda

Blood (2004) 103 (2): 507–516.

https://doi.org/10.1182/blood-2003-05-1435

Published: 2004

Journal Articles

Novel murine myeloid cell lines that exhibit a differentiation switch in response to IL-3 or GM-CSF, or to different constitutively active mutants of the GM-CSF receptor β subunit

Matthew P. McCormack, Thomas J. Gonda

Blood (2000) 95 (1): 120–127.

https://doi.org/10.1182/blood.V95.1.120

Published: 2000

Journal Articles

Saturation Mutagenesis of the β Subunit of the Human Granulocyte-Macrophage Colony-Stimulating Factor Receptor Shows Clustering of Constitutive Mutations, Activation of ERK MAP Kinase and STAT Pathways, and Differential β Subunit Tyrosine Phosphorylation

Brendan J. Jenkins, Timothy J. Blake, Thomas J. Gonda

Blood (1998) 92 (6): 1989–2002.

https://doi.org/10.1182/blood.V92.6.1989

Published: 1998

Journal Articles

Expression of Constitutively Activated Human c-Kit in Myb Transformed Early Myeloid Cells Leads to Factor Independence, Histiocytic Differentiation, and Tumorigenicity

Petranel Ferrao, Thomas J. Gonda, Leonie K. Ashman

Blood (1997) 90 (11): 4539–4552.

https://doi.org/10.1182/blood.V90.11.4539

Published: 1997

Journal Articles

Expression of Activated Mutants of the Human Interleukin-3/Interleukin-5/Granulocyte-Macrophage Colony-Stimulating Factor Receptor Common β Subunit in Primary Hematopoietic Cells Induces Factor-Independent Proliferation and Differentiation

Matthew P. McCormack, Thomas J. Gonda

Blood (1997) 90 (4): 1471–1481.

https://doi.org/10.1182/blood.V90.4.1471

Published: 1997

Journal Articles

Activating Mutations in Cytokine Receptors: Implications for Receptor Function and Role in Disease

Thomas J. Gonda, Richard J. D'Andrea

Blood (1997) 89 (2): 355–369.

https://doi.org/10.1182/blood.V89.2.355

Published: 1997

NARROW

MYB deficiency leads to myeloid neoplasia too

Childhood acute myeloid leukemia shows a high level of germline predisposition

Rare Variants Affecting the Fanconi Anaemia DNA Repair Genes Associate with Increased Risk for AML

Metabolic Profiling of Adult Acute Myeloid Leukemia (AML)

Rare and Common Germline Variants Contribute to Occurrence of Myelodysplastic Syndrome

Vascular Niche E-Selectin Protects Acute Myeloid Leukaemia Stem Cells from Chemotherapy

Whole Exome Sequencing of Acute Myeloid Leukaemia Patients Identifies Somatic and Germline Mutations in Fanconi Anaemia Genes

An ENU Mutagenesis Screen of FLT3-ITD Knock-in Mice Identifies Novel Gene Mutations That Lead to an Exacerbated Myeloproliferative Neoplasm

Interaction of c-Myb with p300 is required for the induction of acute myeloid leukemia (AML) by human AML oncogenes

Interaction of c-Myb with p300 Is Required for the Induction of Acute Myeloid Leukemia by Human AML Oncogenes, and Represents a Potential Therapeutic Target.

A recessive screen for genes regulating hematopoietic stem cells

Alternative modes of GM-CSF receptor activation revealed using activated mutants of the common β-subunit

A Recessive Embryonic Screen for Genes Regulating Hematopoietic Stem Cell and Blood Cell Generation and Function.

Identification of Novel MYB Target Genes

Constitutive mutants of the GM-CSF receptor reveal multiple pathways leading to myeloid cell survival, proliferation, and granulocyte-macrophage differentiation

Novel murine myeloid cell lines that exhibit a differentiation switch in response to IL-3 or GM-CSF, or to different constitutively active mutants of the GM-CSF receptor β subunit

Saturation Mutagenesis of the β Subunit of the Human Granulocyte-Macrophage Colony-Stimulating Factor Receptor Shows Clustering of Constitutive Mutations, Activation of ERK MAP Kinase and STAT Pathways, and Differential β Subunit Tyrosine Phosphorylation

Expression of Constitutively Activated Human c-Kit in Myb Transformed Early Myeloid Cells Leads to Factor Independence, Histiocytic Differentiation, and Tumorigenicity

Expression of Activated Mutants of the Human Interleukin-3/Interleukin-5/Granulocyte-Macrophage Colony-Stimulating Factor Receptor Common β Subunit in Primary Hematopoietic Cells Induces Factor-Independent Proliferation and Differentiation

Activating Mutations in Cytokine Receptors: Implications for Receptor Function and Role in Disease

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ASH Publications

American Society of Hematology

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ASH Publications

American Society of Hematology

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