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Michelle Perugini
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Journal Articles

Hypermethylation of GADD45A Defines a Methylation Profile Distinct to Mutant IDH1/2 , and Correlates with More Aggressive AML

Saumya E Samaraweera, PhD, Francine E. Garrett-Bakelman, MD PhD, Yaseswini Neelamraju, Michelle Perugini, PhD, Debora A. Casolari, PhD, Diana Iarossi, Sarah C Bray, PhD, Caroline Sheridan, Tak C Lee, M.S., Ing Soo Tiong, MBChB, Silke Danner, Nik Cummings, BSc, Monica L. Guzman, PhD, Gail J. Roboz, Luen Bik To, MBBS, FRACP, FRCPA, PhD, Andrew Wei, Christopher E. Mason, PhD, Christopher Y. Park, MD PhD, Ross L. Levine, MD, Martin Carroll, MD, Michael W. Becker, MD, Ian D Lewis, MBBS, PhD FRACP, FRCPA, Ari Melnick, MD, Richard D'Andrea, PhD
Journal: Blood
Blood (2016) 128 (22): 2877.
https://doi.org/10.1182/blood.V128.22.2877.2877
Published: 2016
Journal Articles

Rare and Common Germline Variants Contribute to Occurrence of Myelodysplastic Syndrome

Christopher N Hahn, PhD, Milena Babic, BMPharBio (Hons), Andreas W Schreiber, PhD, Monika M Kutyna, MSc, L Amilia Wee, BSc (Hons), Anna L Brown, PhD, Michelle Perugini, PhD, Deepak Singhal, MD FRCPA, Smita Hiwase, PhD, Jinghua Feng, PhD, Wendy T Parker, PhD, Sarah Moore, BSc (Hon), FFSc (RCPA), Peter G Bardy, MBBS, FRACP, FRCPA, Russell Saal, MMSc,BSMedTech, Paula Marlton, MBBS, FRACP, FRCPA, Andrew S. Moore, MBBS, FRACP, PhD, Thomas J Gonda, PhD, Paul Leo, PhD, Susan Branford, PhD, Richard J D'Andrea, PhD, Ian D Lewis, MBBS, PhD FRACP, FRCPA, Luen Bik To, MBBS, PhD, Hamish S Scott, BSc, PhD FFSc (RCPA), Devendra Hiwase, MBBS, FRACP, FRCPA, MD PhD
Journal: Blood
Blood (2015) 126 (23): 1644.
https://doi.org/10.1182/blood.V126.23.1644.1644
Published: 2015
Journal Articles

The Significance of GADD45A Promoter DNA Hypermethylation in AML: Association with IDH1/2 and TET2 Mutation

Michelle Perugini, PhD, Saumya E Samaraweera, PhD, Anna L Brown, PhD, Nik Cummings, BSc, Silke Danner, Ing Soo Tiong, MBChB, Francine E Garrett-Bakelman, MD PhD, Martin P. Carroll, MD, Michael W. Becker, MD, Stephen S. Chung, MD, Christopher Y. Park, MD PhD, Christopher E Mason, PhD, Monica L. Guzman, PhD, Ross L. Levine, MD, Ari M Melnick, MD, Luen Bik To, MBBS, PhD, Andrew H Wei, MBBS, PhD, Ian D Lewis, MBBS, PhD, Richard J D'Andrea, PhD
Journal: Blood
Blood (2014) 124 (21): 69.
https://doi.org/10.1182/blood.V124.21.69.69
Published: 2014
Journal Articles

Methylation of the Proximal Promoter of GADD45A Is Common in Acute Myeloid Leukemia and Is Associated with Poor Survival.

Richard J D'Andrea, PhD, Michelle Perugini, PhD, Sonya M Diakiw, PhD, Chung H Kok, PhD, Diana Salerno, Nik Cummings, BSc, Anna L Brown, PhD, Silke Danner, Peter G Bardy, MBBS, FRACP, FRCPA, Andrew H Wei, MBBS, PhD, L. Bik To, MD, Ian D Lewis, MBBS, PhD
Journal: Blood
Blood (2012) 120 (21): 2396.
https://doi.org/10.1182/blood.V120.21.2396.2396
Published: 2012
Journal Articles

A Regulatory Promoter Polymorphism and Hypermethylation of Intron 1 Are Associated with Reduced Expression of KLF5 and Inferior Survival in AML

Anna L Brown, PhD, Sonya M Diakiw, PhD, Michelle Perugini, PhD, Nik Cummings, BSc, Andrew H Wei, MBBS, PhD, L. Bik To, MD, Ian D Lewis, MBBS, PhD, Richard J D'Andrea, PhD
Journal: Blood
Blood (2012) 120 (21): 3508.
https://doi.org/10.1182/blood.V120.21.3508.3508
Published: 2012
Journal Articles

Expression of Erythroid Transcription Factors Are Decreased in a RPS19 Knockdown Cell Line Model of Diamond Blackfan Anaemia

Sarah C E Bray, PhD, Amilia Wee, BSc (hons), Michelle Perugini, PhD, L. Bik To, MD, Richard J D'Andrea, PhD
Journal: Blood
Blood (2012) 120 (21): 3473.
https://doi.org/10.1182/blood.V120.21.3473.3473
Published: 2012
Journal Articles

BCR-ABL-Induced Downregulation of GADD45G in Chronic Myeloid Leukemia

Debora A Casolari, PhD, Jun Ishiko, MD, PhD, Michelle Perugini, PhD, Richard J D'Andrea, PhD, Junia V Melo, MD, PhD
Journal: Blood
Blood (2012) 120 (21): 3731.
https://doi.org/10.1182/blood.V120.21.3731.3731
Published: 2012
Journal Articles

Methylation of a Single CpG in the GADD45A Proximal Promoter Is Associated with Poor Survival in Acute Myeloid Leukemia,

Richard J D'Andrea, PhD, Michelle Perugini, PhD, Chung H Kok, PhD, Diana Salerno, Silke Danner, Peter G Bardy, MBBS, FRACP, FRCPA, Andrew H Wei, MBBS, PhD, L. Bik To, MD, Ian D Lewis, MBBS, PhD
Journal: Blood
Blood (2011) 118 (21): 3540.
https://doi.org/10.1182/blood.V118.21.3540.3540
Published: 2011
Journal Articles

Alternative modes of GM-CSF receptor activation revealed using activated mutants of the common β-subunit

Michelle Perugini, Anna L. Brown, Diana G. Salerno, Grant W. Booker, Cvetan Stojkoski, Timothy R. Hercus, Angel F. Lopez, Margaret L. Hibbs, Thomas J. Gonda, Richard J. D'Andrea
Journal: Blood
Blood (2010) 115 (16): 3346–3353.
https://doi.org/10.1182/blood-2009-08-235846
Published: 2010
Includes: Supplemental data
Journal Articles

The GM-CSF Receptor Utilises Members of the Canonical Wnt-Signaling Pathway during Macrophage Differentiation

Anna Brown, BSc, PhD, Diana Salerno, Christopher Wilkinson, Michelle Perugini, Chung Kok, Greg Goodall, Patricia Solomon, Thomas Gonda, Richard D’Andrea, PhD
Journal: Blood
Blood (2008) 112 (11): 3856.
https://doi.org/10.1182/blood.V112.11.3856.3856
Published: 2008
Journal Articles

Common Leukemic Signaling Pathways Identified by Comparative Analysis of GM-CSF and FLT3 Activated Receptor Mutations.

Richard D’Andrea, PhD, Michelle Perugini, BSc(Hons), Chung Kok, BSc(Hons), Christopher Wilkinson, PhD, Anna Brown, PhD, Thomas Gonda, PhD
Journal: Blood
Blood (2006) 108 (11): 1912.
https://doi.org/10.1182/blood.V108.11.1912.1912
Published: 2006