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Journal Articles

Delayed Trp53 Activation Protects Dnmt3a -Mutant Haematopoietic Stem Cells from Inflammatory Attrition

Ludovica Marando, George Giotopoulos, Pedro Madrigal, Dhoyazan M A Azazi, Ryan Asby, Maria Erendira Calleja-Cervantes, David Lara-Astiaso, Nicola K. Wilson, Rebecca Hannah, Jaana Bagri, Elsa Barnard, Sarah J Horton, Berthold Gottgens, Elli Papaemmanuil, Shuchi Agrawal Singh, Malgorzata Gozdecka, George S Vassiliou, Brian J P Huntly

Blood (2024) 144 (Supplement 1): 190.

https://doi.org/10.1182/blood-2024-201612

Published: 2024

Journal Articles

Multimodal Single Cell Analysis Reveals Hematopoietic Changes across the Human Lifespan

Tomoya Isobe, Mariana Quiroga Londoño, Nicole Mende, Emily Stephenson, Deena Iskander, Simone Webb, Issac Goh, Vijay Shanmugiah, Rebecca Hannah, Anindita Roy, Irene Roberts, Elisa Laurenti, Muzlifah Haniffa, Nicola K. Wilson, Berthold Gottgens

Blood (2024) 144 (Supplement 1): 2659.

https://doi.org/10.1182/blood-2024-204131

Published: 2024

Journal Articles

A Novel in Vitro Model of Pre-Leukemic Competition Reveals “Super-Competitive” TET2-Mutant Hematopoietic Stem Cell Clones

Lilia Cabrera-Cosme, Juan Rubio-Lara, Ellie Bennett, Joanna Milek, Maria Jassinskaja, Sandy MacDonald, Karen Hogg, Nicola K. Wilson, Berthold Gottgens, David Kent

Blood (2024) 144 (Supplement 1): 4115.

https://doi.org/10.1182/blood-2024-207127

Published: 2024

Journal Articles

Adaptation to ex vivo culture reduces human hematopoietic stem cell activity independently of the cell cycle

Blood (2024) 144 (7): 729–741.

https://doi.org/10.1182/blood.2023021426

Published: 2024

Includes: Supplemental data

Journal Articles

Circadian Rhythms Metabolically Regulate Bone Marrow Retained Primitive Hematopoietic Stem Cell Size and Function

Priyasmita Chakrabarti, Nicola K. Wilson, Abhishek K. Singh, Iwo Kucinski, Lizeth-Alejandra Ordonez-Moreno, Sony Sharma, Sarah J. Kinston, Montaser B. Haddad, Orit Kollet, Ekaterina Petrovich-Kopitman, Avik Choudhuri, Leonard I. Zon, Jose A. Cancelas, John E. Dick, Stephanie Xie, Bertie Göttgens, Tsvee Lapidot

Blood (2023) 142 (Supplement 1): 2672.

https://doi.org/10.1182/blood-2023-186260

Published: 2023

Journal Articles

A Multimodal Single Cell Atlas of Adult Murine Haematopoiesis Reveals Nine Differentiation Trajectories and Epigenetic Regulatory Programs

Katherine Sturgess, Vijay Shanmugiah, Tomoya Isobe, Melania Barlie, Nicola K. Wilson, Berthold Gottgens

Blood (2023) 142 (Supplement 1): 2686.

https://doi.org/10.1182/blood-2023-189941

Published: 2023

Journal Articles

Introduction to a review series on single-cell genomics: getting ready for clinical impact in leukemia and myeloid neoplasms

Katherine H. M. Sturgess, Nicola K. Wilson, Berthold Göttgens

Blood (2023) 141 (4): 323–325.

https://doi.org/10.1182/blood.2022017361

Published: 2023

Journal Articles

STAT1 is essential for HSC function and maintains MHCII hi stem cells that resist myeloablation and neoplastic expansion

Blood (2022) 140 (14): 1592–1606.

https://doi.org/10.1182/blood.2021014009

Published: 2022

Includes: Supplemental data

Journal Articles

p57Kip2 regulates embryonic blood stem cells by controlling sympathoadrenal progenitor expansion

Chrysa Kapeni, Leslie Nitsche, Alastair M. Kilpatrick, Nicola K. Wilson, Kankan Xia, Bahar Mirshekar-Syahkal, Vashe Chandrakanthan, Camille Malouf, John E. Pimanda, Berthold Göttgens, Kristina Kirschner, Simon R. Tomlinson, Katrin Ottersbach

Blood (2022) 140 (5): 464–477.

https://doi.org/10.1182/blood.2021014853

Published: 2022

Includes: Supplemental data

Journal Articles

Unique molecular and functional features of extramedullary hematopoietic stem and progenitor cell reservoirs in humans

Blood (2022) 139 (23): 3387–3401.

https://doi.org/10.1182/blood.2021013450

Published: 2022

Includes: Supplemental data

Journal Articles

Cohesin-dependent regulation of gene expression during differentiation is lost in cohesin-mutated myeloid malignancies

Daniel Sasca, Haiyang Yun, George Giotopoulos, Jakub Szybinski, Theo Evan, Nicola K. Wilson, Moritz Gerstung, Paolo Gallipoli, Anthony R. Green, Robert Hills, Nigel Russell, Cameron S. Osborne, Elli Papaemmanuil, Berthold Göttgens, Peter Campbell, Brian J. P. Huntly

Blood (2019) 134 (24): 2195–2208.

https://doi.org/10.1182/blood.2019001553

Published: 2019

Includes: Supplemental data

Journal Articles

Single-cell approaches identify the molecular network driving malignant hematopoietic stem cell self-renewal

Mairi S. Shepherd, Juan Li, Nicola K. Wilson, Caroline A. Oedekoven, Jiangbing Li, Miriam Belmonte, Juergen Fink, Janine C. M. Prick, Dean C. Pask, Tina L. Hamilton, Dirk Loeffler, Anjana Rao, Timm Schröder, Berthold Göttgens, Anthony R. Green, David G. Kent

Blood (2018) 132 (8): 791–803.

https://doi.org/10.1182/blood-2017-12-821066

Published: 2018

Includes: Supplemental data

Journal Articles

A single-cell hematopoietic landscape resolves 8 lineage trajectories and defects in Kit mutant mice

Joakim S. Dahlin, Fiona K. Hamey, Blanca Pijuan-Sala, Mairi Shepherd, Winnie W. Y. Lau, Sonia Nestorowa, Caleb Weinreb, Samuel Wolock, Rebecca Hannah, Evangelia Diamanti, David G. Kent, Berthold Göttgens, Nicola K. Wilson

Blood (2018) 131 (21): e1–e11.

https://doi.org/10.1182/blood-2017-12-821413

Published: 2018

Includes: Supplemental data

Journal Articles

A single-cell resolution map of mouse hematopoietic stem and progenitor cell differentiation

Sonia Nestorowa, Fiona K. Hamey, Blanca Pijuan Sala, Evangelia Diamanti, Mairi Shepherd, Elisa Laurenti, Nicola K. Wilson, David G. Kent, Berthold Göttgens

Blood (2016) 128 (8): e20–e31.

https://doi.org/10.1182/blood-2016-05-716480

Published: 2016

Includes: Supplemental data

Journal Articles

Integrated genome-scale analysis of the transcriptional regulatory landscape in a blood stem/progenitor cell model

Nicola K. Wilson, Stefan Schoenfelder, Rebecca Hannah, Manuel Sánchez Castillo, Judith Schütte, Vasileios Ladopoulos, Joanna Mitchelmore, Debbie K. Goode, Fernando J. Calero-Nieto, Victoria Moignard, Adam C. Wilkinson, Isabel Jimenez-Madrid, Sarah Kinston, Mikhail Spivakov, Peter Fraser, Berthold Göttgens

Blood (2016) 127 (13): e12–e23.

https://doi.org/10.1182/blood-2015-10-677393

Published: 2016

Includes: Supplemental data

Journal Articles

Genome-wide analysis of transcriptional regulators in human HSPCs reveals a densely interconnected network of coding and noncoding genes

Dominik Beck, Julie A. I. Thoms, Dilmi Perera, Judith Schütte, Ashwin Unnikrishnan, Kathy Knezevic, Sarah J. Kinston, Nicola K. Wilson, Tracey A. O’Brien, Berthold Göttgens, Jason W. H. Wong, John E. Pimanda

Blood (2013) 122 (14): e12–e22.

https://doi.org/10.1182/blood-2013-03-490425

Published: 2013

Includes: Supplemental data

Journal Articles

GFI1 and GFI1B control the loss of endothelial identity of hemogenic endothelium during hematopoietic commitment

Christophe Lancrin, Milena Mazan, Monika Stefanska, Rahima Patel, Monika Lichtinger, Guilherme Costa, Özge Vargel, Nicola K. Wilson, Tarik Möröy, Constanze Bonifer, Berthold Göttgens, Valerie Kouskoff, Georges Lacaud

Blood (2012) 120 (2): 314–322.

https://doi.org/10.1182/blood-2011-10-386094

Published: 2012

Includes: Multimedia, Supplemental data

Journal Articles

The Lymphoblastic Leukemia Gene 1 (Lyl1) Regulates Lymphoid Specification and Maintenance of Early T Lineage Progenitors

Fabian Zohren, MD, George Souroullas, PhD, Min Luo, Ph.D., Ulrike Gerdemann, MD, Nicola K Wilson, Berthold Göttgens, DPhil, Georgi L. Lukov, MD, PhD, Margaret Goodell, Ph.D.

Blood (2011) 118 (21): 548.

https://doi.org/10.1182/blood.V118.21.548.548

Published: 2011

Journal Articles

Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells

Mathias Leddin, Chiara Perrod, Maarten Hoogenkamp, Saeed Ghani, Salam Assi, Sven Heinz, Nicola K. Wilson, George Follows, Jörg Schönheit, Lena Vockentanz, Ali M. Mosammam, Wei Chen, Daniel G. Tenen, David R. Westhead, Berthold Göttgens, Constanze Bonifer, Frank Rosenbauer

Blood (2011) 117 (10): 2827–2838.

https://doi.org/10.1182/blood-2010-08-302976

Published: 2011

Includes: Supplemental data

Journal Articles

Expression of the leukemia oncogene Lmo2 is controlled by an array of tissue-specific elements dispersed over 100 kb and bound by Tal1/Lmo2, Ets, and Gata factors

Josette-Renée Landry, Nicolas Bonadies, Sarah Kinston, Kathy Knezevic, Nicola K. Wilson, S. Helen Oram, Mary Janes, Sandie Piltz, Michelle Hammett, Jacinta Carter, Tina Hamilton, Ian J. Donaldson, Georges Lacaud, Jonathan Frampton, George Follows, Valerie Kouskoff, Berthold Göttgens

Blood (2009) 113 (23): 5783–5792.

https://doi.org/10.1182/blood-2008-11-187757

Published: 2009

Includes: Supplemental data

NARROW

Delayed Trp53 Activation Protects Dnmt3a -Mutant Haematopoietic Stem Cells from Inflammatory Attrition

Multimodal Single Cell Analysis Reveals Hematopoietic Changes across the Human Lifespan

A Novel in Vitro Model of Pre-Leukemic Competition Reveals “Super-Competitive” TET2-Mutant Hematopoietic Stem Cell Clones

Adaptation to ex vivo culture reduces human hematopoietic stem cell activity independently of the cell cycle

Circadian Rhythms Metabolically Regulate Bone Marrow Retained Primitive Hematopoietic Stem Cell Size and Function

A Multimodal Single Cell Atlas of Adult Murine Haematopoiesis Reveals Nine Differentiation Trajectories and Epigenetic Regulatory Programs

Introduction to a review series on single-cell genomics: getting ready for clinical impact in leukemia and myeloid neoplasms

STAT1 is essential for HSC function and maintains MHCII hi stem cells that resist myeloablation and neoplastic expansion

p57Kip2 regulates embryonic blood stem cells by controlling sympathoadrenal progenitor expansion

Unique molecular and functional features of extramedullary hematopoietic stem and progenitor cell reservoirs in humans

Cohesin-dependent regulation of gene expression during differentiation is lost in cohesin-mutated myeloid malignancies

Single-cell approaches identify the molecular network driving malignant hematopoietic stem cell self-renewal

A single-cell hematopoietic landscape resolves 8 lineage trajectories and defects in Kit mutant mice

A single-cell resolution map of mouse hematopoietic stem and progenitor cell differentiation

Integrated genome-scale analysis of the transcriptional regulatory landscape in a blood stem/progenitor cell model

Genome-wide analysis of transcriptional regulators in human HSPCs reveals a densely interconnected network of coding and noncoding genes

GFI1 and GFI1B control the loss of endothelial identity of hemogenic endothelium during hematopoietic commitment

The Lymphoblastic Leukemia Gene 1 (Lyl1) Regulates Lymphoid Specification and Maintenance of Early T Lineage Progenitors

Two distinct auto-regulatory loops operate at the PU.1 locus in B cells and myeloid cells

Expression of the leukemia oncogene Lmo2 is controlled by an array of tissue-specific elements dispersed over 100 kb and bound by Tal1/Lmo2, Ets, and Gata factors

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American Society of Hematology

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ASH Publications

American Society of Hematology

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