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Fall of the mutants: T cells targeting BCR-ABL
Consensus guidelines for the diagnosis and management of patients with classic hairy cell leukemia
Evaluating surveillance imaging for diffuse large B-cell lymphoma and Hodgkin lymphoma
How I treat FLT3-mutated AML
Ph-like acute lymphoblastic leukemia: a high-risk subtype in adults
BCR-ABL–specific T-cell therapy in Ph+ ALL patients on tyrosine-kinase inhibitors
A phase 3 randomized trial comparing inolimomab vs usual care in steroid-resistant acute GVHD
Issue Archive
February 2 2017
Table of Contents
INSIDE BLOOD COMMENTARIES
INSIDE BLOOD COMMENTARY
Fall of the mutants: T cells targeting BCR-ABL
Clinical Trials & Observations
BLOOD SPOTLIGHT
REVIEW ARTICLE
Consensus guidelines for the diagnosis and management of patients with classic hairy cell leukemia
Clinical Trials & Observations
Michael R. Grever,Omar Abdel-Wahab,Leslie A. Andritsos,Versha Banerji,Jacqueline Barrientos,James S. Blachly,Timothy G. Call,Daniel Catovsky,Claire Dearden,Judit Demeter,Monica Else,Francesco Forconi,Alessandro Gozzetti,Anthony D. Ho,James B. Johnston,Jeffrey Jones,Gunnar Juliusson,Eric Kraut,Robert J. Kreitman,Loree Larratt,Francesco Lauria,Gerard Lozanski,Emili Montserrat,Sameer A. Parikh,Jae H. Park,Aaron Polliack,Graeme R. Quest,Kanti R. Rai,Farhad Ravandi,Tadeusz Robak,Alan Saven,John F. Seymour,Tamar Tadmor,Martin S. Tallman,Constantine Tam,Enrico Tiacci,Xavier Troussard,Clive S. Zent,Thorsten Zenz,Pier Luigi Zinzani,Brunangelo Falini
EVIDENCE-BASED FOCUSED REVIEW
Evaluating surveillance imaging for diffuse large B-cell lymphoma and Hodgkin lymphoma
Clinical Trials & Observations
HOW I TREAT
How I treat FLT3-mutated AML
Clinical Trials & Observations
CLINICAL TRIALS AND OBSERVATIONS
Ph-like acute lymphoblastic leukemia: a high-risk subtype in adults
Clinical Trials & Observations
Nitin Jain,Kathryn G. Roberts,Elias Jabbour,Keyur Patel,Agda Karina Eterovic,Ken Chen,Patrick Zweidler-McKay,Xinyan Lu,Gloria Fawcett,Sa A. Wang,Sergej Konoplev,Richard C. Harvey,I-Ming Chen,Debbie Payne-Turner,Marcus Valentine,Deborah Thomas,Guillermo Garcia-Manero,Farhad Ravandi,Jorge Cortes,Steven Kornblau,Susan O’Brien,Sherry Pierce,Jeffrey Jorgensen,Kenna R. Mills Shaw,Cheryl L. Willman,Charles G. Mullighan,Hagop Kantarjian,Marina Konopleva
BCR-ABL–specific T-cell therapy in Ph+ ALL patients on tyrosine-kinase inhibitors
Clinical Trials & Observations
Brief Report
Patrizia Comoli,Sabrina Basso,Giovanni Riva,Patrizia Barozzi,Ilaria Guido,Antonella Gurrado,Giuseppe Quartuccio,Laura Rubert,Ivana Lagreca,Daniela Vallerini,Fabio Forghieri,Monica Morselli,Paola Bresciani,Angela Cuoghi,Ambra Paolini,Elisabetta Colaci,Roberto Marasca,Antonio Cuneo,Lorenzo Iughetti,Tommaso Trenti,Franco Narni,Robin Foà,Marco Zecca,Mario Luppi,Leonardo Potenza
HEMATOPOIESIS AND STEM CELLS
G-CSF-induced sympathetic tone provokes fever and primes antimobilizing functions of neutrophils via PGE2
Yuko Kawano,Chie Fukui,Masakazu Shinohara,Kanako Wakahashi,Shinichi Ishii,Tomohide Suzuki,Mari Sato,Noboru Asada,Hiroki Kawano,Kentaro Minagawa,Akiko Sada,Tomoyuki Furuyashiki,Satoshi Uematsu,Shizuo Akira,Toshimitsu Uede,Shuh Narumiya,Toshimitsu Matsui,Yoshio Katayama
LYMPHOID NEOPLASIA
HSP90 promotes Burkitt lymphoma cell survival by maintaining tonic B-cell receptor signaling
Roland Walter,Kuan-Ting Pan,Carmen Doebele,Federico Comoglio,Katarzyna Tomska,Hanibal Bohnenberger,Ryan M. Young,Laura Jacobs,Ulrich Keller,Halvard Bönig,Michael Engelke,Andreas Rosenwald,Henning Urlaub,Louis M. Staudt,Hubert Serve,Thorsten Zenz,Thomas Oellerich
MYELOID NEOPLASIA
An anti-CD3/anti–CLL-1 bispecific antibody for the treatment of acute myeloid leukemia
Steven R. Leong,Siddharth Sukumaran,Maria Hristopoulos,Klara Totpal,Shannon Stainton,Elizabeth Lu,Alfred Wong,Lucinda Tam,Robert Newman,Brian R. Vuillemenot,Diego Ellerman,Chen Gu,Mary Mathieu,Mark S. Dennis,Allen Nguyen,Bing Zheng,Crystal Zhang,Genee Lee,Yu-Waye Chu,Rodney A. Prell,Kedan Lin,Steven T. Laing,Andrew G. Polson
RED CELLS, IRON, AND ERYTHROPOIESIS
TRANSPLANTATION
GVHD prevents NK-cell–dependent leukemia and virus-specific innate immunity
Mark D. Bunting,Antiopi Varelias,Fernando Souza-Fonseca-Guimaraes,Iona S. Schuster,Katie E. Lineburg,Rachel D. Kuns,Peter Fleming,Kelly R. Locke,Nicholas D. Huntington,Bruce R. Blazar,Steven W. Lane,Siok-Keen Tey,Kelli P. A. MacDonald,Mark J. Smyth,Mariapia A. Degli-Esposti,Geoffrey R. Hill
A phase 3 randomized trial comparing inolimomab vs usual care in steroid-resistant acute GVHD
Clinical Trials & Observations
Gérard Socié,Stéphane Vigouroux,Ibrahim Yakoub-Agha,Jacques-Olivier Bay,Sabine Fürst,Karin Bilger,Felipe Suarez,Mauricette Michallet,Dominique Bron,Philippe Gard,Zakaria Medeghri,Philippe Lehert,Chinglin Lai,Tim Corn,Jean-Paul Vernant
LETTERS TO BLOOD
Somatic STAT5b gain-of-function mutations in early onset nonclonal eosinophilia, urticaria, dermatitis, and diarrhea
Chi A. Ma,Liqiang Xi,Brian Cauff,Adam DeZure,Alexandra F. Freeman,Sophie Hambleton,Gary Kleiner,T. Ronan Leahy,Maureen O’Sullivan,Michelle Makiya,Grainne O’Regan,Stefania Pittaluga,Julie Niemela,Jennifer Stoddard,Sergio D. Rosenzweig,Mark Raffeld,Amy D. Klion,Joshua D. Milner
BLOOD WORK
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Cover Image
Cover Image
Immunohistochemistry staining of a human lymph follicle showing high heat shock protein 90 β (HSP90β) expression in the germinal center. In the article by Walter et al on page 598, the authors investigate the role of HSP90 in Burkitt lymphoma.
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