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Michelle Makiya
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Journal Articles

A Noncoding Germline Variant Creates a Gain-of-Function De Novo Enhancer That up-Regulates IL5 Transcription to Cause Familial Hypereosinophilia, Revealing a Previously Undescribed Mechanism for Human Disease

Jung-Hyun Kim, Abbie Bowman, Senbagavalli Babu, Jan Cools, Sofie Demeyer, Majid Kazemian, Warren Leonard, Jian-Xin Lin, Michelle Makiya, Mathieu Perez, Colin L. Sweeney, Luis M Franco, Neelam Redekar, Justin Lack, Linda Resar, Amy D Klion
Journal: Blood
Blood (2022) 140 (Supplement 1): 1399–1400.
https://doi.org/10.1182/blood-2022-169953
Published: 2022
Journal Articles

Glucocorticoid-induced eosinopenia results from CXCR4-dependent bone marrow migration

So Gun Hong, Noriko Sato, Fanny Legrand, Manasi Gadkari, Michelle Makiya, Kindra Stokes, Katherine N. Howe, Shiqin Judy Yu, Nathaniel Seth Linde, Randall R. Clevenger, Timothy Hunt, Zonghui Hu, Peter L. Choyke, Cynthia E. Dunbar, Amy D. Klion, Luis M. Franco
Journal: Blood
Blood (2020) 136 (23): 2667–2678.
https://doi.org/10.1182/blood.2020005161
Published: 2020
Includes: Multimedia, Supplemental data
Journal Articles

Dexpramipexole as an oral steroid-sparing agent in hypereosinophilic syndromes

Clinical Trials & Observations
Sandhya R. Panch, Michael E. Bozik, Thomas Brown, Michelle Makiya, Calman Prussin, Donald G. Archibald, Gregory T. Hebrank, Mary Sullivan, Xiaoping Sun, Lauren Wetzler, JeanAnne Ware, Michael P. Fay, Cynthia E. Dunbar, Steven I. Dworetzky, Paneez Khoury, Irina Maric, Amy D. Klion
Journal: Blood
Blood (2018) 132 (5): 501–509.
https://doi.org/10.1182/blood-2018-02-835330
Published: 2018
Includes: Supplemental data
Journal Articles

Somatic STAT5b gain-of-function mutations in early onset nonclonal eosinophilia, urticaria, dermatitis, and diarrhea

Chi A. Ma, Liqiang Xi, Brian Cauff, Adam DeZure, Alexandra F. Freeman, Sophie Hambleton, Gary Kleiner, T. Ronan Leahy, Maureen O’Sullivan, Michelle Makiya, Grainne O’Regan, Stefania Pittaluga, Julie Niemela, Jennifer Stoddard, Sergio D. Rosenzweig, Mark Raffeld, Amy D. Klion, Joshua D. Milner
Journal: Blood
Blood (2017) 129 (5): 650–653.
https://doi.org/10.1182/blood-2016-09-737817
Published: 2017
Includes: Supplemental data
Journal Articles

Dexpramipexole As a Steroid-Sparing Agent in Hypereosinophilic Syndromes (HES): An Open-Label Proof-of-Concept Study

Sandhya R. Panch, MD MPH, Michael Bozik, MD, Thomas Brown, RN, Ulrike Demarco, Dipl. Biol., Jamie Hahn, BS, Alexander Komarov, PhD, Tamika Magee, RN, Michelle Makiya, RN, Calman Prussin, MD, Armando Signore, PhD, Mary Sullivan, BA, Lauren Wetzler, MHS, PA, Cynthia E. Dunbar, MD, Steven Dworetzky, PhD, Irina Maric, MD, Amy D Klion, MD
Journal: Blood
Blood (2016) 128 (22): 1327.
https://doi.org/10.1182/blood.V128.22.1327.1327
Published: 2016