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Journal Articles

HMGA1 Chromatin Regulators Disrupt 3D Genome Architecture and Chromatin Looping to Repress MHC II Genes and Drive Immune Evasion during MPN Progression

Linda Resar, Joseph Kim, Audrey-Ann Supreme, Hyunsung Woo, Bailey West, Mariah C. Antopia, Zanshe Thompson, Karen Reddy, Jung-Hyun Kim, Leslie Cope, Raajit Rampal, Richard Koche, Alison R. Moliterno, Jerry L. Spivak

Blood (2024) 144 (Supplement 1): 756.

https://doi.org/10.1182/blood-2024-211336

Published: 2024

Journal Articles

Targeting HMGA1 Epigenetic Regulators and Downstream ETV5 Pathways with Histone Deacetylase Inhibitors in Combination Therapy for Relapsed, Pediatric B-ALL

Linda Resar, Jung-Hyun Kim, Li Z Luo, Katharina Hayer, Camilo Arenas Merizalde, Leslie Cope, Andrei Thomas-Tikhonenko, Sarah K. Tasian

Blood (2024) 144 (Supplement 1): 1361.

https://doi.org/10.1182/blood-2024-211514

Published: 2024

Journal Articles

High Mobility Group A1 (HMGA1) Chromatin Regulators Maintain Quiescent, Regenerative HSC By Repressing IGF1 Networks That Promote Stem Cell Aging

Zanshe Thompson, Li Z Luo, Liping Li, Bowen Wang, Jung-Hyun Kim, Lingling Xian, Bailey West, Leslie Cope, John Lister, Linda Resar

Blood (2024) 144 (Supplement 1): 1277.

https://doi.org/10.1182/blood-2024-211649

Published: 2024

Journal Articles

High Mobility Group A1 Chromatin Regulators Drive Regenerative Capacity during Stress Hematopoiesis through Modulation of TNF-α and Aging Transcriptional Networks

Zanshe Thompson, Li Z Luo, Bowen Wang, Jung-Hyun Kim, Hyunsung Woo, Leslie Cope, Linda Resar

Blood (2023) 142 (Supplement 1): 4050.

https://doi.org/10.1182/blood-2023-189964

Published: 2023

Journal Articles

Single Cell Transcriptomics Reveal That HMGA1 Chromatin Regulators Drive Transcriptional Networks Involved in Megakaryocyte Expansion, Platelet Activation, and Interferon Signaling in JAK2 V617F Myeloproliferative Neoplasms

Zanshe Thompson, Li Z Luo, Liping Li, Bowen Wang, Jung-Hyun Kim, Hyunsung Woo, Bailey West, Anandi Krishnan, Leslie Cope, Alison R. Moliterno, Jerry L. Spivak, Linda Resar

Blood (2023) 142 (Supplement 1): 3145.

https://doi.org/10.1182/blood-2023-190323

Published: 2023

Journal Articles

HMGA1 Chromatin Regulators Drive Immune Evasion in MPN Progression through Epigenetic Rewiring to Repress Antigen Presentation

Joseph Kim, Audrey-Ann Supreme, Bailey West, Mariah C. Antopia, Karen Reddy, Leslie Cope, Jung-Hyun Kim, Raajit K. Rampal, Richard Koche, Jerry L. Spivak, Alison R. Moliterno, Linda Resar

Blood (2023) 142 (Supplement 1): 992.

https://doi.org/10.1182/blood-2023-186452

Published: 2023

Journal Articles

The High Mobility Group A1 Chromatin Regulator Drives Immune Evasion during MPN Progression By Repressing Genes Involved in Antigen Presentation

Joseph Kim, Jung-Hyun Kim, Leslie Cope, Liping Li, Raajit K Rampal, Richard Koche, Jerry L. Spivak, Alison R. Moliterno, Linda Resar

Blood (2022) 140 (Supplement 1): 801–802.

https://doi.org/10.1182/blood-2022-166969

Published: 2022

Journal Articles

HMGA1-ETV5 Axis Is Essential for Relapsed B-Cell Leukemia and Provides Novel Therapeutic Targets

Jung-Hyun Kim, Liping Li, Zixin Zhang, Katharina Hayer, Li Luo, Leslie Cope, Lingling Xian, Andrei Thomas-Tikhonenko, Linda Resar

Blood (2022) 140 (Supplement 1): 3478–3479.

https://doi.org/10.1182/blood-2022-167037

Published: 2022

Journal Articles

A Noncoding Germline Variant Creates a Gain-of-Function De Novo Enhancer That up-Regulates IL5 Transcription to Cause Familial Hypereosinophilia, Revealing a Previously Undescribed Mechanism for Human Disease

Jung-Hyun Kim, Abbie Bowman, Senbagavalli Babu, Jan Cools, Sofie Demeyer, Majid Kazemian, Warren Leonard, Jian-Xin Lin, Michelle Makiya, Mathieu Perez, Colin L. Sweeney, Luis M Franco, Neelam Redekar, Justin Lack, Linda Resar, Amy D Klion

Blood (2022) 140 (Supplement 1): 1399–1400.

https://doi.org/10.1182/blood-2022-169953

Published: 2022

Journal Articles

HMGA1 chromatin regulators induce transcriptional networks involved in GATA2 and proliferation during MPN progression

Blood (2022) 139 (18): 2797–2815.

https://doi.org/10.1182/blood.2021013925

Published: 2022

Includes: Supplemental data

Journal Articles

The High Mobility Group A1 Chromatin Regulator Drives Immune Evasion during MPN Progression By Repressing Genes Involved in Antigen Presentation and Immune Attack

Joseph Kim, Jung-Hyun Kim, Leslie Cope, Liping Li, Raajit Rampal, Richard Koche, Donna M Williams, Jerry L. Spivak, Alison R. Moliterno, Linda Resar

Blood (2021) 138 (Supplement 1): 2546.

https://doi.org/10.1182/blood-2021-151139

Published: 2021

Journal Articles

High Mobility Group A1 (HMGA1) Epigenetic Regulators Induce ETV5 Networks in Relapsed B-Cell Leukemia and Provide Novel Therapeutic Targets

Jung-Hyun Kim, Liping Li, Zixin Zhang, Katharina Hayer, Lingling Xian, Li Luo, Leslie Cope, Andrei Thomas-Tikhonenko, Linda Resar

Blood (2021) 138 (Supplement 1): 707.

https://doi.org/10.1182/blood-2021-152950

Published: 2021

Journal Articles

HMGA1 Chromatin Regulators Drive Progression in Myeloproliferative Neoplasms through Epigenetic Rewiring to Induce Networks Involved in GATA2 and Proliferation

Liping Li, Jung-Hyun Kim, Wenyan Lu, Leslie Cope, Donna M Williams, Joseph Kim, Raajit Rampal, Richard Koche, Lingling Xian, Li Luo, Marija Vasiljevic, Daniel R Matson, Zhizhuang Joe Zhao, Ophelia Rogers, Matthew C. Stubbs, Karen Reddy, Jerry L. Spivak, Alison R. Moliterno, Linda Resar

Blood (2021) 138 (Supplement 1): 625.

https://doi.org/10.1182/blood-2021-144712

Published: 2021

Journal Articles

Hematological Disorders in Human Patients with Son Mutations

Lana Vukadin, Jung-Hyun Kim, PhD, Tara Bly Hackwelder, Nathan Ungerleider, PhD, Erik Flemington, Eun-Young Erin Ahn, PhD

Blood (2019) 134 (Supplement_1): 3709.

https://doi.org/10.1182/blood-2019-130616

Published: 2019

Journal Articles

Investigation of the Significance of Son Isoform mRNA Expression in Patients with Blood Cytopenias with/without Evidence of Myeloid Neoplasia

Jung-Hyun Kim, PhD, Eun-Young Erin Ahn, PhD, Aliyeh Kennedy, Aaron Dinerman, Thomas W Butler, MD

Blood (2018) 132 (Supplement 1): 5123.

https://doi.org/10.1182/blood-2018-99-120211

Published: 2018

Journal Articles

Investigation of the Significance of Son Isoform mRNA Expression in Patients with Blood Cytopenias with/without Evidence of Myeloid Neoplasia

Aaron Dinerman, Jung-Hyun Kim, PhD, Eun-Young Erin Ahn, PhD, Thomas Butler, MD

Blood (2017) 130 (Supplement 1): 5293.

https://doi.org/10.1182/blood.V130.Suppl_1.5293.5293

Published: 2017

Journal Articles

Combinational Treatment of Imatinib and Allicin Synergistically Inhibits the Growth of BCR-ABL-Positive Leukemia and the Emergence of Drug-Resistant Cells

Jamie Lim, Jung-Hyun Kim, PhD, Eun-Young Erin Ahn, PhD

Blood (2017) 130 (Supplement 1): 4992.

https://doi.org/10.1182/blood.V130.Suppl_1.4992.4992

Published: 2017

Journal Articles

Son and Its Alternatively Spliced Isoforms Control MLL Complex-Mediated H3K4me3 and Transcription of Leukemia-Associated Genes

Jung-Hyun Kim, PhD, Thomas W. Butler, MD, Eun-Young Erin Ahn, PhD

Blood (2015) 126 (23): 2426.

https://doi.org/10.1182/blood.V126.23.2426.2426

Published: 2015

Journal Articles

Aberrant Upregulation Of Alternatively Spliced Isoforms Of Son In Myeloid Leukemia: Implications In Hematopoiesis and Leukemogenesis

Jung-Hyun Kim, Ph.D., Christopher J Hickey, Ph.D, E.Y. Erin Ahn, Ph.D.

Blood (2013) 122 (21): 3731.

https://doi.org/10.1182/blood.V122.21.3731.3731

Published: 2013

NARROW

HMGA1 Chromatin Regulators Disrupt 3D Genome Architecture and Chromatin Looping to Repress MHC II Genes and Drive Immune Evasion during MPN Progression

Targeting HMGA1 Epigenetic Regulators and Downstream ETV5 Pathways with Histone Deacetylase Inhibitors in Combination Therapy for Relapsed, Pediatric B-ALL

High Mobility Group A1 (HMGA1) Chromatin Regulators Maintain Quiescent, Regenerative HSC By Repressing IGF1 Networks That Promote Stem Cell Aging

High Mobility Group A1 Chromatin Regulators Drive Regenerative Capacity during Stress Hematopoiesis through Modulation of TNF-α and Aging Transcriptional Networks

Single Cell Transcriptomics Reveal That HMGA1 Chromatin Regulators Drive Transcriptional Networks Involved in Megakaryocyte Expansion, Platelet Activation, and Interferon Signaling in JAK2 V617F Myeloproliferative Neoplasms

HMGA1 Chromatin Regulators Drive Immune Evasion in MPN Progression through Epigenetic Rewiring to Repress Antigen Presentation

The High Mobility Group A1 Chromatin Regulator Drives Immune Evasion during MPN Progression By Repressing Genes Involved in Antigen Presentation

HMGA1-ETV5 Axis Is Essential for Relapsed B-Cell Leukemia and Provides Novel Therapeutic Targets

A Noncoding Germline Variant Creates a Gain-of-Function De Novo Enhancer That up-Regulates IL5 Transcription to Cause Familial Hypereosinophilia, Revealing a Previously Undescribed Mechanism for Human Disease

HMGA1 chromatin regulators induce transcriptional networks involved in GATA2 and proliferation during MPN progression

The High Mobility Group A1 Chromatin Regulator Drives Immune Evasion during MPN Progression By Repressing Genes Involved in Antigen Presentation and Immune Attack

High Mobility Group A1 (HMGA1) Epigenetic Regulators Induce ETV5 Networks in Relapsed B-Cell Leukemia and Provide Novel Therapeutic Targets

HMGA1 Chromatin Regulators Drive Progression in Myeloproliferative Neoplasms through Epigenetic Rewiring to Induce Networks Involved in GATA2 and Proliferation

Hematological Disorders in Human Patients with Son Mutations

Investigation of the Significance of Son Isoform mRNA Expression in Patients with Blood Cytopenias with/without Evidence of Myeloid Neoplasia

Investigation of the Significance of Son Isoform mRNA Expression in Patients with Blood Cytopenias with/without Evidence of Myeloid Neoplasia

Combinational Treatment of Imatinib and Allicin Synergistically Inhibits the Growth of BCR-ABL-Positive Leukemia and the Emergence of Drug-Resistant Cells

Son and Its Alternatively Spliced Isoforms Control MLL Complex-Mediated H3K4me3 and Transcription of Leukemia-Associated Genes

Aberrant Upregulation Of Alternatively Spliced Isoforms Of Son In Myeloid Leukemia: Implications In Hematopoiesis and Leukemogenesis

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American Society of Hematology

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ASH Publications

American Society of Hematology

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