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Issue Archive

Volume 128, Issue 23
December 8 2016
Issue Cover

Table of Contents

BLOOD FLASHBACK

Carbone PP, Bono V, Frei E III, Brindley CO. Clinical studies with vincristine. Blood. 1963;21(5):640-647.
View Articletitled, Carbone PP, Bono V, Frei E III, Brindley CO. Clinical studies with vincristine. <em>Blood</em>. 1963;21(5):<span class="related-article">640-647</span>.

INSIDE BLOOD COMMENTARIES

INSIDE BLOOD COMMENTARY
Targeting hedgehog in T-ALL
Shai Izraeli
View Articletitled, Targeting hedgehog in T-ALL
INSIDE BLOOD COMMENTARY
Deregulation of NF-κB, ie, a useful PMBL marker
Paul M. Barr
View Articletitled, Deregulation of NF-κB, ie, a useful PMBL marker
INSIDE BLOOD COMMENTARY
Twisting IL-1 signaling to kill CML stem cells
Lorenzo Stramucci,Danilo Perrotti
View Articletitled, Twisting IL-1 signaling to kill CML stem cells
INSIDE BLOOD COMMENTARY
Mechanism of O2-sensitive red cell properties
John S. Gibson
View Articletitled, Mechanism of O<sub>2</sub>-sensitive red cell properties
INSIDE BLOOD COMMENTARY
Ticagrelor: agonising over its mechanisms of action
William A. E. Parker,Robert F. Storey
View Articletitled, Ticagrelor: agonising over its mechanisms of action
INSIDE BLOOD COMMENTARY
Losing your GRP on platelet activation
Stephen P. Holly
View Articletitled, Losing your GRP on platelet activation

PERSPECTIVE

MGUS to myeloma: a mysterious gammopathy of underexplored significance
Madhav V. Dhodapkar
View Articletitled, MGUS to myeloma: a mysterious gammopathy of underexplored significance

REVIEW ARTICLES

Strategies before, during, and after hematopoietic cell transplantation to improve T-cell immune reconstitution
Coco de Koning,Stefan Nierkens,Jaap Jan Boelens
View Articletitled, Strategies before, during, and after hematopoietic cell transplantation to improve T-cell immune reconstitution
Haploidentical hematopoietic transplantation for the cure of leukemia: from its biology to clinical translation
Clinical Trials & Observations
Antonella Mancusi,Loredana Ruggeri,Andrea Velardi
View Articletitled, Haploidentical hematopoietic transplantation for the cure of leukemia: from its biology to clinical translation

HOW I TREAT

How I treat resistant cytomegalovirus infection in hematopoietic cell transplantation recipients
Firas El Chaer,Dimpy P. Shah,Roy F. Chemaly
View Articletitled, How I treat resistant cytomegalovirus infection in hematopoietic cell transplantation recipients

HEMATOPOIESIS AND STEM CELLS

TGF-β inhibitors stimulate red blood cell production by enhancing self-renewal of BFU-E erythroid progenitors
Brief Report
Xiaofei Gao,Hsiang-Ying Lee,Edroaldo Lummertz da Rocha,Cheng Zhang,Yi-Fen Lu,Dandan Li,Yuxiong Feng,Jideofor Ezike,Russell R. Elmes,M. Inmaculada Barrasa,Patrick Cahan,Hu Li,George Q. Daley,Harvey F. Lodish
View Articletitled, TGF-β inhibitors stimulate red blood cell production by enhancing self-renewal of BFU-E erythroid progenitors
Supplemental data

LYMPHOID NEOPLASIA

Hedgehog pathway activation in T-cell acute lymphoblastic leukemia predicts response to SMO and GLI1 inhibitors
Antonis Dagklis,Sofie Demeyer,Jolien De Bie,Enrico Radaelli,Daphnie Pauwels,Sandrine Degryse,Olga Gielen,Carmen Vicente,Roel Vandepoel,Ellen Geerdens,Anne Uyttebroeck,Nancy Boeckx,Charles E. de Bock,Jan Cools
View Articletitled, Hedgehog pathway activation in T-cell acute lymphoblastic leukemia predicts response to SMO and GLI1 inhibitors
Supplemental data
Caspase-3–dependent cleavage of Bcl-xL in the stroma exosomes is required for their uptake by hematological malignant cells
Ioulia Vardaki,Claire Sanchez,Pedro Fonseca,Magnus Olsson,Dimitrios Chioureas,George Rassidakis,Anders Ullén,Boris Zhivotovsky,Magnus Björkholm,Theocharis Panaretakis
View Articletitled, Caspase-3–dependent cleavage of Bcl-xL in the stroma exosomes is required for their uptake by hematological malignant cells
Supplemental data
Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma
Clinical Trials & Observations Brief Report
Larry Mansouri,Daniel Noerenberg,Emma Young,Elena Mylonas,Maysaa Abdulla,Mareike Frick,Fazila Asmar,Viktor Ljungström,Markus Schneider,Kenichi Yoshida,Aron Skaftason,Tatjana Pandzic,Blanca Gonzalez,Anna Tasidou,Nils Waldhueter,Alfredo Rivas-Delgado,Maria Angelopoulou,Marita Ziepert,Christopher Maximilian Arends,Lucile Couronné,Dido Lenze,Claudia D. Baldus,Christian Bastard,Jessica Okosun,Jude Fitzgibbon,Bernd Dörken,Hans G. Drexler,Damien Roos-Weil,Clemens A. Schmitt,Helga D. Munch-Petersen,Thorsten Zenz,Martin-Leo Hansmann,Jonathan C. Strefford,Gunilla Enblad,Olivier A. Bernard,Elisabeth Ralfkiaer,Martin Erlanson,Penelope Korkolopoulou,Magnus Hultdin,Theodora Papadaki,Kirsten Grønbæk,Armando Lopez-Guillermo,Seishi Ogawa,Ralf Küppers,Kostas Stamatopoulos,Niki Stavroyianni,George Kanellis,Andreas Rosenwald,Elias Campo,Rose-Marie Amini,German Ott,Theodoros P. Vassilakopoulos,Michael Hummel,Richard Rosenquist,Frederik Damm
View Articletitled, Frequent <em>NFKBIE</em> deletions are associated with poor outcome in primary mediastinal B-cell lymphoma
Supplemental data

MYELOID NEOPLASIA

Inhibition of interleukin-1 signaling enhances elimination of tyrosine kinase inhibitor–treated CML stem cells
Bin Zhang,Su Chu,Puneet Agarwal,Victoria L. Campbell,Lisa Hopcroft,Heather G. Jørgensen,Allen Lin,Karl Gaal,Tessa L. Holyoake,Ravi Bhatia
View Articletitled, Inhibition of interleukin-1 signaling enhances elimination of tyrosine kinase inhibitor–treated CML stem cells
IL1RAP antibodies block IL-1–induced expansion of candidate CML stem cells and mediate cell killing in xenograft models
Helena Ågerstam,Nils Hansen,Sofia von Palffy,Carl Sandén,Kristian Reckzeh,Christine Karlsson,Henrik Lilljebjörn,Niklas Landberg,Maria Askmyr,Carl Högberg,Marianne Rissler,Kimmo Porkka,Hans Wadenvik,Satu Mustjoki,Johan Richter,Marcus Järås,Thoas Fioretos
View Articletitled, IL1RAP antibodies block IL-1–induced expansion of candidate CML stem cells and mediate cell killing in xenograft models
Supplemental data
LXR agonist treatment of blastic plasmacytoid dendritic cell neoplasm restores cholesterol efflux and triggers apoptosis
Adam Ceroi,David Masson,Anne Roggy,Christophe Roumier,Cécile Chagué,Thierry Gauthier,Laure Philippe,Baptiste Lamarthée,Fanny Angelot-Delettre,Francis Bonnefoy,Sylvain Perruche,Sabeha Biichle,Claude Preudhomme,Elisabeth Macintyre,Laurent Lagrost,Francine Garnache-Ottou,Philippe Saas
View Articletitled, LXR agonist treatment of blastic plasmacytoid dendritic cell neoplasm restores cholesterol efflux and triggers apoptosis
Supplemental data

RED CELLS, IRON, AND ERYTHROPOIESIS

Reversible binding of hemoglobin to band 3 constitutes the molecular switch that mediates O2 regulation of erythrocyte properties
Haiyan Chu,Mary M. McKenna,Nathan A. Krump,Suilan Zheng,Laurel Mendelsohn,Swee Lay Thein,Lisa J. Garrett,David M. Bodine,Philip S. Low
View Articletitled, Reversible binding of hemoglobin to band 3 constitutes the molecular switch that mediates O<sub>2</sub> regulation of erythrocyte properties
Supplemental data

THROMBOSIS AND HEMOSTASIS

Inverse agonism at the P2Y12 receptor and ENT1 transporter blockade contribute to platelet inhibition by ticagrelor
Riyaad Aungraheeta,Alexandra Conibear,Mark Butler,Eamonn Kelly,Sven Nylander,Andrew Mumford,Stuart J. Mundell
View Articletitled, Inverse agonism at the P2Y<sub>12</sub> receptor and ENT1 transporter blockade contribute to platelet inhibition by ticagrelor
Human CalDAG-GEFI deficiency increases bleeding and delays αIIbβ3 activation
Brief Report
Hisashi Kato,Yozo Nakazawa,Yumi Kurokawa,Hirokazu Kashiwagi,Yoichiro Morikawa,Daisuke Morita,Fumiaki Banno,Shigenori Honda,Yuzuru Kanakura,Yoshiaki Tomiyama
View Articletitled, Human CalDAG-GEFI deficiency increases bleeding and delays αIIbβ3 activation
Supplemental data
PDGFB, a new candidate plasma biomarker for venous thromboembolism: results from the VEREMA affinity proteomics study
e-blood
Maria Bruzelius,Maria Jesus Iglesias,Mun-Gwan Hong,Laura Sanchez-Rivera,Beata Gyorgy,Juan Carlos Souto,Mattias Frånberg,Claudia Fredolini,Rona J. Strawbridge,Margareta Holmström,Anders Hamsten,Mathias Uhlén,Angela Silveira,Jose Manuel Soria,David M. Smadja,Lynn M. Butler,Jochen M. Schwenk,Pierre-Emmanuel Morange,David-Alexandre Trégouët,Jacob Odeberg
View Articletitled, PDGFB, a new candidate plasma biomarker for venous thromboembolism: results from the VEREMA affinity proteomics study
Supplemental data

TRANSPLANTATION

Excellent T-cell reconstitution and survival depend on low ATG exposure after pediatric cord blood transplantation
Clinical Trials & Observations
Rick Admiraal,Caroline A. Lindemans,Charlotte van Kesteren,Marc B. Bierings,A. Birgitta Versluijs,Stefan Nierkens,Jaap Jan Boelens
View Articletitled, Excellent T-cell reconstitution and survival depend on low ATG exposure after pediatric cord blood transplantation
Supplemental data

BLOOD WORK

RUSH for G6PD!
Uqba Khan,Tarik Hadid
View Articletitled, RUSH for G6PD!
von Willebrand disease type 2B
Eric McGinnis,Suzanne M. Vercauteren
View Articletitled, von Willebrand disease type 2B

ERRATUM

Crivello P, Heinold A, Rebmann V, et al. Functional distance between recipient and donor HLA-DPB1 determines nonpermissive mismatches in unrelated HCT. Blood. 2016;128(1):120-129.
View Articletitled, Crivello P, Heinold A, Rebmann V, et al. Functional distance between recipient and donor HLA-DPB1 determines nonpermissive mismatches in unrelated HCT. <em>Blood.</em> 2016;128(1):120-129.
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