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Journal Articles

Lactate Dehydrogenase to Carboxyhemoglobin Ratio As a Biomarker of Heme Release to Heme Processing Is Associated with Higher Tricuspid Regurgitant Jet Velocity and Early Death in Sickle Cell Disease

Annelies J. Van Vuren, MD, Laurel Mendelsohn, BS, Richard van Wijk, PhD, Caterina P. Minniti, MD, John Baird, MD, Gregory J Kato, MD, Eduard J. van Beers, MD PhD

Blood (2019) 134 (Supplement_1): 2274.

https://doi.org/10.1182/blood-2019-124048

Published: 2019

Journal Articles

Neutrophil Extracellular Traps Are an Intrinsic Feature in Sickle Cell Disease

Emilia Alina Barbu, Venina Marcela Dominical, PhD, Laurel Mendelsohn, BS, James Nichols, RN, Darlene Allen, MT(ASCP), Swee Lay Thein, DSc,FRCP,FRCPath,MBBS,MRCPath,MRCP

Blood (2018) 132 (Supplement 1): 3651.

https://doi.org/10.1182/blood-2018-99-118723

Published: 2018

Journal Articles

Reversible binding of hemoglobin to band 3 constitutes the molecular switch that mediates O 2 regulation of erythrocyte properties

Haiyan Chu, Mary M. McKenna, Nathan A. Krump, Suilan Zheng, Laurel Mendelsohn, Swee Lay Thein, Lisa J. Garrett, David M. Bodine, Philip S. Low

Blood (2016) 128 (23): 2708–2716.

https://doi.org/10.1182/blood-2016-01-692079

Published: 2016

Includes: Supplemental data

Journal Articles

Hemoglobin S Oxidation Promotes Plasma-Derived Microparticle Membrane Alterations and Toxicity

Sirsendu Jana, PhD, Michael B Strader, PhD, Tigist Kassa, PhD, Fantao Meng, PhD, Wayne Hicks, PhD, Ivan Tarandovskiy, PhD, Silvia De Paoli, PhD, Jan Simak, PhD, Jeffery L Miller, MD, Laurel Mendelsohn, BSc., Jim Nichols, RSN, Swee Lay Thein, MD, John D. Belcher, PhD, Gregory M Vercellotti, MD, Abdu Alayash, PhD

Blood (2016) 128 (22): 856.

https://doi.org/10.1182/blood.V128.22.856.856

Published: 2016

Journal Articles

Heme Augments Toll-like Receptor 4 Signalling in Sickle Cell and Healthy Control Monocytes

Pradeep K Dagur, PhD, J. Philip McCoy, PhD, J Nichols, Laurel Mendelsohn, BS, C Seamon, Gregory J Kato, MD, Eduard J van Beers, MD PhD

Blood (2015) 126 (23): 2167.

https://doi.org/10.1182/blood.V126.23.2167.2167

Published: 2015

Journal Articles

Plasma FGF23 Is a Biomarker for Left Ventricular Hypertrophy and Mortality in Adults with Sickle Cell Anemia Chronic Kidney Disease

Chia-Hao Liu, PhD, Olusola Laja, BA, MSc, Laurel Mendelsohn, BS, Kathleen Vaughan, BA, Lena Diaw, PhD, Jefferey Kopp, MD, James G. Taylor, MD

Blood (2015) 126 (23): 2171.

https://doi.org/10.1182/blood.V126.23.2171.2171

Published: 2015

Journal Articles

Quantification of Anti-Sickling Effect of Aes-103 in Sickle Cell Disease Using an in Vitro Microfluidic Assay

E. Du, PhD, Laurel Mendelsohn, BS, James S. Nichols, RN, Ming Dao, PhD, Gregory J. Kato, MD

Blood (2014) 124 (21): 2699.

https://doi.org/10.1182/blood.V124.21.2699.2699

Published: 2014

Journal Articles

Iron, Expression of the Pattern Recognition Receptor-Inflammasome System, and Early Death in Adults with Sickle Cell Disease

Eduard J. van Beers, MD PhD, Yanqin Yang, MS, Nalini Raghavachari, PhD, Xin Tian, PhD, Darlene Allen, MT(ASCP), James S. Nichols, RN, Laurel Mendelsohn, BS, Sergei A. Nekhai, PhD, Victor R. Gordeuk, MD, James G. Taylor VI, MD, Gregory J. Kato, MD

Blood (2014) 124 (21): 2702.

https://doi.org/10.1182/blood.V124.21.2702.2702

Published: 2014

Journal Articles

End-Alveolar Carbon Monoxide As a Measure of Erythrocyte Survival and Hemolytic Severity in Sickle Cell Disease

Caterina P. Minniti, MD, John H. Baird, Dihua Xu, Laurel Mendelsohn, BS, Rehan Saiyed, B.S., Mary Jackson, RN, James Nichols, RN, Daniel Kim-Shapiro, PhD, Yang Xia, MD PhD, Gregory J. Kato, MD

Blood (2014) 124 (21): 2696.

https://doi.org/10.1182/blood.V124.21.2696.2696

Published: 2014

Journal Articles

Stimulation of Nitric Oxide Synthase Activity By Plasma Apolipoproteins: a Biomarker of Endothelial Function in Adults with Sickle Cell Disease

Xunde Wang, PhD, Laurel Mendelsohn, BS, Lita Freeman, PhD, Boris Vaisman, PhD, Alan Remaley, MD, Gregory J. Kato, MD

Blood (2014) 124 (21): 4015.

https://doi.org/10.1182/blood.V124.21.4015.4015

Published: 2014

Journal Articles

Heme-bound iron activates placenta growth factor in erythroid cells via erythroid Krüppel-like factor

Xunde Wang, Laurel Mendelsohn, Heather Rogers, Susan Leitman, Nalini Raghavachari, Yanqin Yang, Yu Ying Yau, Michael Tallack, Andrew Perkins, James G. Taylor, VI, Constance Tom Noguchi, Gregory J. Kato

Blood (2014) 124 (6): 946–954.

https://doi.org/10.1182/blood-2013-11-539718

Published: 2014

Journal Articles

Microvascular oxygen consumption during sickle cell pain crisis

Carol A. Rowley, Allison K. Ikeda, Miles Seidel, Tiffany C. Anaebere, Matthew D. Antalek, Catherine Seamon, Anna K. Conrey, Laurel Mendelsohn, James Nichols, Alexander M. Gorbach, Gregory J. Kato, Hans Ackerman

Blood (2014) 123 (20): 3101–3104.

https://doi.org/10.1182/blood-2013-11-533406

Published: 2014

Includes: Supplemental data

Journal Articles

Iron Containing Compound Stimulates Expression of Pulmonary Hypertension Promoting Factor PlGF

Xunde Wang, Gregory J. Kato, MD, Laurel Mendelsohn

Blood (2011) 118 (21): 900.

https://doi.org/10.1182/blood.V118.21.900.900

Published: 2011

Journal Articles

High levels of placenta growth factor in sickle cell disease promote pulmonary hypertension

Nambirajan Sundaram, Anitaben Tailor, Laurel Mendelsohn, Janaka Wansapura, Xunde Wang, Tomoyasu Higashimoto, Michael W. Pauciulo, William Gottliebson, Vijay K. Kalra, William C. Nichols, Gregory J. Kato, Punam Malik

Blood (2010) 116 (1): 109–112.

https://doi.org/10.1182/blood-2009-09-244830

Published: 2010

Includes: Supplemental data

Journal Articles

Placental Growth Factor Is Elevated in Patients with Sickle Cell Disease and Associated with Pulmonary Hypertension, Hemolysis, Inflammation, Iron Overload, and Hepatic Dysfunction.

Laurel Mendelsohn, Anitaben Tailor, Ph.D., Gregory J Kato, MD

Blood (2009) 114 (22): 1531.

https://doi.org/10.1182/blood.V114.22.1531.1531

Published: 2009

Journal Articles

NT-Pro Brain Natriuretic Peptide Levels and the Risk of Stroke and Death in the Cooperative Study of Sickle Cell Disease.

Roberto F Machado, MD, Mariana Hildescheim, Laurel Mendelsohn, Gregory J Kato, Mark T Gladwin, MD

Blood (2009) 114 (22): 1541.

https://doi.org/10.1182/blood.V114.22.1541.1541

Published: 2009

Journal Articles

Phenotypic and Genetic Discordance in Monozygotic Twins with Sickle Anemia and ð-Thalassemia.

Maxwell P. Westerman, MD, Arnold Pizzey, Herbert J. Meiselman, PhD, Narla Mohandas, DSc, Gregory J. Kato, MD, Mark Gladwin, MD, Laurel Mendelsohn, Jan Dumanski, John B Porter

Blood (2009) 114 (22): 5084.

https://doi.org/10.1182/blood.V114.22.5084.5084

Published: 2009

Journal Articles

Sickle Cell Mice with Hypoxia-Reoxygenation Have Oxidative and Inflammatory Liver Injury - toward a New Experimental Model for Vaso- Occlusive Injury

Lewis L. Hsu, MD, PhD, Sruti Shiva, PhD, Caroline Mendelsohn, Michael R Hsu, Audrey C Noguchi, Laurel Mendelsohn, Mark Gladwin, MD

Blood (2008) 112 (11): 121.

https://doi.org/10.1182/blood.V112.11.121.121

Published: 2008

Journal Articles

Pulmonary Hypertension in Adults and Children with Sickle Cell Disease in Nigeria: Prevalence, Clinical Characteristics and Role of Endemic Tropical Infections.

Zakari Y. Aliyu, MD, MPH, Sachdev Vandana, MD, Aisha I. Mamman, MBBS, Aliyu Babadoko, MBBS, Peter Akpanpe, Ester Attah, Yusuf Suleiman, Nurudeen Aliyu, Jamilu Yusuf, BA, Laurel Mendelsohn, BS, Wynona Coles, BS, Solomon Danbauchi, MBBS, James Taylor, MD, Oswaldo Castro, MD, Victor R. Gordeuk, MD, William C. Blackwelder, MD, Gregory J. Kato, MD, Mark T. Gladwin

Blood (2007) 110 (11): 3793.

https://doi.org/10.1182/blood.V110.11.3793.3793

Published: 2007

NARROW

Lactate Dehydrogenase to Carboxyhemoglobin Ratio As a Biomarker of Heme Release to Heme Processing Is Associated with Higher Tricuspid Regurgitant Jet Velocity and Early Death in Sickle Cell Disease

Neutrophil Extracellular Traps Are an Intrinsic Feature in Sickle Cell Disease

Reversible binding of hemoglobin to band 3 constitutes the molecular switch that mediates O 2 regulation of erythrocyte properties

Hemoglobin S Oxidation Promotes Plasma-Derived Microparticle Membrane Alterations and Toxicity

Heme Augments Toll-like Receptor 4 Signalling in Sickle Cell and Healthy Control Monocytes

Plasma FGF23 Is a Biomarker for Left Ventricular Hypertrophy and Mortality in Adults with Sickle Cell Anemia Chronic Kidney Disease

Quantification of Anti-Sickling Effect of Aes-103 in Sickle Cell Disease Using an in Vitro Microfluidic Assay

Iron, Expression of the Pattern Recognition Receptor-Inflammasome System, and Early Death in Adults with Sickle Cell Disease

End-Alveolar Carbon Monoxide As a Measure of Erythrocyte Survival and Hemolytic Severity in Sickle Cell Disease

Stimulation of Nitric Oxide Synthase Activity By Plasma Apolipoproteins: a Biomarker of Endothelial Function in Adults with Sickle Cell Disease

Heme-bound iron activates placenta growth factor in erythroid cells via erythroid Krüppel-like factor

Microvascular oxygen consumption during sickle cell pain crisis

Iron Containing Compound Stimulates Expression of Pulmonary Hypertension Promoting Factor PlGF

High levels of placenta growth factor in sickle cell disease promote pulmonary hypertension

Placental Growth Factor Is Elevated in Patients with Sickle Cell Disease and Associated with Pulmonary Hypertension, Hemolysis, Inflammation, Iron Overload, and Hepatic Dysfunction.

NT-Pro Brain Natriuretic Peptide Levels and the Risk of Stroke and Death in the Cooperative Study of Sickle Cell Disease.

Phenotypic and Genetic Discordance in Monozygotic Twins with Sickle Anemia and ð-Thalassemia.

Sickle Cell Mice with Hypoxia-Reoxygenation Have Oxidative and Inflammatory Liver Injury - toward a New Experimental Model for Vaso- Occlusive Injury

Pulmonary Hypertension in Adults and Children with Sickle Cell Disease in Nigeria: Prevalence, Clinical Characteristics and Role of Endemic Tropical Infections.

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American Society of Hematology

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American Society of Hematology

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