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Journal Articles

Phase 1 Multiple Ascending Dose Study of Safety, Tolerability, and Pharmacokinetics/Pharmacodynamics of Mitapivat (AG-348) in Subjects with Sickle Cell Disease

Julia Z. Xu, MDMS, Anna Conrey, NP, Ingrid Frey, RN, BSN, MS, James Nichols, RN, Laurel A Menapace, MD, Laxminath Tumburu, PhD, Timothy Lequang, MSc, Quan Li, PhD, Emily Dunkelberger, PhD, Eric Henry, PhD, Troy Cellmer, PhD, Varsha Iyer, Heidi Mangus, BS, Charles Kung, PhD, Lenny Dang, PhD, Penelope A. Kosinski, MS, Peter Hawkins, PhD, Neal Jeffries, PhD, William Eaton, MD, Swee Lay Thein, DSc, FRCP, MBBS, MRCP
Journal: Blood
Blood (2020) 136 (Supplement 1): 21–22.
https://doi.org/10.1182/blood-2020-137716
Published: 2020
Journal Articles

A Machine Learning Algorithm to Improve Risk Assessment for Patients with Sickle Cell Disease

Vandana Sachdev, MD, Yuan Gu, PhD, James Nichols, RN, Wen Li, RCS, Stanislav Sidenko, RCS, Darlene Allen, MT(ASCP), Colin Wu, PhD, Swee Lay Thein, DSc, MBBS
Journal: Blood
Blood (2019) 134 (Supplement_1): 893.
https://doi.org/10.1182/blood-2019-125846
Published: 2019
Journal Articles

Neutrophil Extracellular Traps Are an Intrinsic Feature in Sickle Cell Disease

Emilia Alina Barbu, Venina Marcela Dominical, PhD, Laurel Mendelsohn, BS, James Nichols, RN, Darlene Allen, MT(ASCP), Swee Lay Thein, DSc,FRCP,FRCPath,MBBS,MRCPath,MRCP
Journal: Blood
Blood (2018) 132 (Supplement 1): 3651.
https://doi.org/10.1182/blood-2018-99-118723
Published: 2018
Journal Articles

Ventilation-Perfusion Scan Is Superior to CT Pulmonary Angiography in Detection of Chronic Thromboembolic Pulmonary Hypertension in SCD Adults

Alem Mehari, MD MS, Norris E. Igbineweka, MBBS, BSc (Hons), MRCP, Darlene Allen, MT(ASCP), James Nichols, RN, Swee Lay Thein, DSc,FRCP,FRCPath,MBBS,MRCPath,MRCP, Nargues Weir, MD
Journal: Blood
Blood (2017) 130 (Supplement 1): 2248.
https://doi.org/10.1182/blood.V130.Suppl_1.2248.2248
Published: 2017
Journal Articles

End-Alveolar Carbon Monoxide As a Measure of Erythrocyte Survival and Hemolytic Severity in Sickle Cell Disease

Caterina P. Minniti, MD, John H. Baird, Dihua Xu, Laurel Mendelsohn, BS, Rehan Saiyed, B.S., Mary Jackson, RN, James Nichols, RN, Daniel Kim-Shapiro, PhD, Yang Xia, MD PhD, Gregory J. Kato, MD
Journal: Blood
Blood (2014) 124 (21): 2696.
https://doi.org/10.1182/blood.V124.21.2696.2696
Published: 2014
Journal Articles

Microvascular oxygen consumption during sickle cell pain crisis

Clinical Trials & Observations Brief Report
Carol A. Rowley, Allison K. Ikeda, Miles Seidel, Tiffany C. Anaebere, Matthew D. Antalek, Catherine Seamon, Anna K. Conrey, Laurel Mendelsohn, James Nichols, Alexander M. Gorbach, Gregory J. Kato, Hans Ackerman
Journal: Blood
Blood (2014) 123 (20): 3101–3104.
https://doi.org/10.1182/blood-2013-11-533406
Published: 2014
Includes: Supplemental data
Journal Articles

Topical Sodium Nitrite Is Effective In Reducing Leg Ulcer-Associated Pain In Patients With Sickle Cell Disease

Caterina P. Minniti, MD, Caroline Cantilena, Dihua Xu, MD, Anna K. Conrey, RN, Marlene Peters-Lawrence, RN, RT, George Grimes, Pharm.D., James Nichols, RN, Karen Axelrod, Kathleen Rizzo, Gregory J. Kato, MD
Journal: Blood
Blood (2013) 122 (21): 2236.
https://doi.org/10.1182/blood.V122.21.2236.2236
Published: 2013
Journal Articles

The Mechanism of Hemolysis in Sickle Cell Anemia.

Tennille Presley, PhD, Lauren Bain, Samir Ballas, MD, James Nichols, RN, Hernan Sabio, MD, Mark Gladwin, MD, Gregory J. Kato, MD, Daniel Kim-Shapiro, PhD
Journal: Blood
Blood (2008) 112 (11): 1439.
https://doi.org/10.1182/blood.V112.11.1439.1439
Published: 2008
Journal Articles

Atorvastatin Therapy Restores Nitric Oxide-Dependent Vascular Responsiveness in Patients with Sickle Cell Disease.

Gregory J. Kato, MD, Christian Hunter, PhD, Lori Hunter, RN, Andre Dejam, MD, PhD, Roberto Machado, MD, Kyle Mack, MD, Jose Villagra, MD, James Nichols, RN, Wynona Coles, RT, Vandana Sachdev, MD, Richard Cannon, MD, Mark T. Gladwin, MD
Journal: Blood
Blood (2004) 104 (11): 239.
https://doi.org/10.1182/blood.V104.11.239.239
Published: 2004
Journal Articles

Severe Pulmonary Hypertension in Sickle Cell Patients with HIV Infection.

Onyinye C. Onyekwere, M.D., Gregory J. Kato, M.D., Roberto Machado, M.D., Wynoma Coles, R.T., James Nichols, R.N., Lori Hunter, R.N., Mark T. Gladwin, M.D., Oswaldo L. Castro, M.D.
Journal: Blood
Blood (2004) 104 (11): 3757.
https://doi.org/10.1182/blood.V104.11.3757.3757
Published: 2004
Journal Articles

Acute on Chronic Pulmonary Hypertension in Patients with Sickle Cell Disease.

Gregory J. Kato, MD, Sabrina Martyr, BS, Roberto Machado, MD, Vandana Sachdev, MD, Inez Ernst, Lori Hunter, RN, Wynona Coles, RT, James Nichols, RN, Christian J. Hunter, PhD, Mark T. Gladwin, MD
Journal: Blood
Blood (2004) 104 (11): 1669.
https://doi.org/10.1182/blood.V104.11.1669.1669
Published: 2004