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Issue Archive

Volume 123, Issue 16
April 17 2014
Issue Cover

Table of Contents

INSIDE BLOOD COMMENTARIES

INSIDE BLOOD COMMENTARY
Toward the “ideal” inhibitor of NETs
Christian Con Yost
View Articletitled, Toward the “ideal” inhibitor of NETs
INSIDE BLOOD COMMENTARY
Genomic clues to ethnic differences in ALL
Sharon A. Savage
View Articletitled, Genomic clues to ethnic differences in ALL
INSIDE BLOOD COMMENTARY
Jumping translocations and high-risk myeloma
Gareth J. Morgan
View Articletitled, Jumping translocations and high-risk myeloma
INSIDE BLOOD COMMENTARY
Novel signaling axis in CML-initiating cells
Cheng Cheng Zhang
View Articletitled, Novel signaling axis in CML-initiating cells
INSIDE BLOOD COMMENTARY
cIAPs and XIAP reduce RIPKs to silence
Arnaud Jacquel,Patrick Auberger
View Articletitled, cIAPs and XIAP reduce RIPKs to silence
INSIDE BLOOD COMMENTARY
Platelets join the world of “Omics”
Beth Boulden Warren,Jorge A. Di Paola
View Articletitled, Platelets join the world of “Omics”

BLOOD WORK

“Russell-like” bodies in Philadelphia chromosome–positive B-lymphoblastic leukemia
Silvia T. Bunting,Glen Lew
View Articletitled, “Russell-like” bodies in Philadelphia chromosome–positive B-lymphoblastic leukemia
Hemophagocytic lymphohistiocytosis and disseminated histoplasmosis
Alina M. Huang
View Articletitled, Hemophagocytic lymphohistiocytosis and disseminated histoplasmosis

REVIEW ARTICLE

Notch signaling: switching an oncogene to a tumor suppressor
Camille Lobry,Philmo Oh,Marc R. Mansour,A. Thomas Look,Iannis Aifantis
View Articletitled, Notch signaling: switching an oncogene to a tumor suppressor
TAM receptors, Gas6, and protein S: roles in inflammation and hemostasis
Jonathan H. M. van der Meer,Tom van der Poll,Cornelis van ‘t Veer
View Articletitled, TAM receptors, Gas6, and protein S: roles in inflammation and hemostasis

REVIEW SERIES

Immunotoxins for leukemia
Clinical Trials & Observations
Alan S. Wayne,David J. FitzGerald,Robert J. Kreitman,Ira Pastan
View Articletitled, Immunotoxins for leukemia

HOW I TREAT

How I treat: the clinical differentiation and initial treatment of adult patients with atypical hemolytic uremic syndrome
Spero R. Cataland,Haifeng M. Wu
View Articletitled, How I treat: the clinical differentiation and initial treatment of adult patients with atypical hemolytic uremic syndrome

CLINICAL TRIALS AND OBSERVATIONS

Serological investigation of patients with a previous history of heparin-induced thrombocytopenia who are reexposed to heparin
Clinical Trials & Observations
Theodore E. Warkentin,Jo-Ann I. Sheppard
View Articletitled, Serological investigation of patients with a previous history of heparin-induced thrombocytopenia who are reexposed to heparin
The impact of health care settings on survival time of patients with chronic myeloid leukemia
Clinical Trials & Observations Brief Report
Michael Lauseker,Joerg Hasford,Markus Pfirrmann,Rüdiger Hehlmann,for the German CML Study Group,for the German CML Study Group,for the German CML Study Group,for the German CML Study Group
View Articletitled, The impact of health care settings on survival time of patients with chronic myeloid leukemia
Supplemental data

LYMPHOID NEOPLASIA

The role of KIR genes and their cognate HLA class I ligands in childhood acute lymphoblastic leukemia
Adam J. de Smith,Kyle M. Walsh,Martha B. Ladner,Siming Zhang,Carmen Xiao,Franziska Cohen,Theodore B. Moore,Anand P. Chokkalingam,Catherine Metayer,Patricia A. Buffler,Elizabeth A. Trachtenberg,Joseph L. Wiemels
View Articletitled, The role of <em>KIR</em> genes and their cognate <em>HLA</em> class I ligands in childhood acute lymphoblastic leukemia
Supplemental data
Jumping translocations of 1q12 in multiple myeloma: a novel mechanism for deletion of 17p in cytogenetically defined high-risk disease
Jeffrey R. Sawyer,Erming Tian,Christoph J. Heuck,Joshua Epstein,Donald J. Johann,Charles M. Swanson,Janet L. Lukacs,Marian Johnson,Regina Binz,Angela Boast,Gael Sammartino,Saad Usmani,Maurizio Zangari,Sarah Waheed,Frits van Rhee,Bart Barlogie
View Articletitled, Jumping translocations of 1q12 in multiple myeloma: a novel mechanism for deletion of 17p in cytogenetically defined high-risk disease
Supplemental data
Inherited genetic susceptibility to monoclonal gammopathy of unknown significance
CME Brief Report
Niels Weinhold,David C. Johnson,Andrew C. Rawstron,Asta Försti,Chi Doughty,Jayaram Vijayakrishnan,Peter Broderick,Nasrin B. Dahir,Dil B. Begum,Fay J. Hosking,Kwee Yong,Brian A. Walker,Per Hoffmann,Thomas W. Mühleisen,Christian Langer,Elisabeth Dörner,Karl-Heinz Jöckel,Lewin Eisele,Markus M. Nöthen,Dirk Hose,Faith E. Davies,Hartmut Goldschmidt,Gareth J. Morgan,Kari Hemminki,Richard S. Houlston
View Articletitled, Inherited genetic susceptibility to monoclonal gammopathy of unknown significance
Supplemental data

MYELOID NEOPLASIA

Functions of flt3 in zebrafish hematopoiesis and its relevance to human acute myeloid leukemia
Bai-Liang He,Xiangguo Shi,Cheuk Him Man,Alvin C. H. Ma,Stephen C. Ekker,Howard C. H. Chow,Chi Wai Eric So,William W. L. Choi,Wenqing Zhang,Yiyue Zhang,Anskar Y. H. Leung
View Articletitled, Functions of flt3 in zebrafish hematopoiesis and its relevance to human acute myeloid leukemia
Supplemental data
A novel tescalcin-sodium/hydrogen exchange axis underlying sorafenib resistance in FLT3-ITD+ AML
Cheuk Him Man,Stephen S. Y. Lam,Murphy K. H. Sun,Howard C. H. Chow,Harinder Gill,Yok Lam Kwong,Anskar Y. H. Leung
View Articletitled, A novel tescalcin-sodium/hydrogen exchange axis underlying sorafenib resistance in FLT3-ITD<sup>+</sup> AML
Supplemental data
The IL-2/CD25 axis maintains distinct subsets of chronic myeloid leukemia-initiating cells
Chiharu I. Kobayashi,Keiyo Takubo,Hiroshi Kobayashi,Ayako Nakamura-Ishizu,Hiroaki Honda,Keisuke Kataoka,Keiki Kumano,Hideo Akiyama,Tetsuo Sudo,Mineo Kurokawa,Toshio Suda
View Articletitled, The IL-2/CD25 axis maintains distinct subsets of chronic myeloid leukemia-initiating cells
Supplemental data

PHAGOCYTES, GRANULOCYTES, AND MYELOPOIESIS

Bortezomib inhibits STAT5-dependent degradation of LEF-1, inducing granulocytic differentiation in congenital neutropenia CD34+ cells
Kshama Gupta,Inna Kuznetsova,Olga Klimenkova,Maksim Klimiankou,Johann Meyer,Malcolm A. S. Moore,Cornelia Zeidler,Karl Welte,Julia Skokowa
View Articletitled, Bortezomib inhibits STAT5-dependent degradation of LEF-1, inducing granulocytic differentiation in congenital neutropenia CD34<sup>+</sup> cells
Supplemental data
cIAPs and XIAP regulate myelopoiesis through cytokine production in an RIPK1- and RIPK3-dependent manner
W. Wei-Lynn Wong,James E. Vince,Najoua Lalaoui,Kate E. Lawlor,Diep Chau,Aleksandra Bankovacki,Holly Anderton,Donald Metcalf,Lorraine O’Reilly,Philipp J. Jost,James M. Murphy,Warren S. Alexander,Andreas Strasser,David L. Vaux,John Silke
View Articletitled, cIAPs and XIAP regulate myelopoiesis through cytokine production in an RIPK1- and RIPK3-dependent manner
Supplemental data
Synchronized integrin engagement and chemokine activation is crucial in neutrophil extracellular trap–mediated sterile inflammation
Jan Rossaint,Jan M. Herter,Hugo Van Aken,Markus Napirei,Yvonne Döring,Christian Weber,Oliver Soehnlein,Alexander Zarbock
View Articletitled, Synchronized integrin engagement and chemokine activation is crucial in neutrophil extracellular trap–mediated sterile inflammation
Supplemental data

PLATELETS AND THROMBOPOIESIS

Human platelet microRNA-mRNA networks associated with age and gender revealed by integrated plateletomics
e-blood
Lukas M. Simon,Leonard C. Edelstein,Srikanth Nagalla,Angela B. Woodley,Edward S. Chen,Xianguo Kong,Lin Ma,Paolo Fortina,Satya Kunapuli,Michael Holinstat,Steven E. McKenzie,Jing-fei Dong,Chad A. Shaw,Paul F. Bray
View Articletitled, Human platelet microRNA-mRNA networks associated with age and gender revealed by integrated plateletomics
Supplemental data

THROMBOSIS AND HEMOSTASIS

Control of VWF A2 domain stability and ADAMTS13 access to the scissile bond of full-length VWF
Christopher J. Lynch,David A. Lane,Brenda M. Luken
View Articletitled, Control of VWF A2 domain stability and ADAMTS13 access to the scissile bond of full-length VWF
Supplemental data

CONTINUING MEDICAL EDUCATION (CME) QUESTIONS

Genetic susceptibility to MGUS
CME
View Articletitled, Genetic susceptibility to MGUS
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