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Issue Archive

Volume 123, Issue 15
April 10 2014
Issue Cover

Table of Contents

EDITORIAL

Introduction to the series of reviews on “Antibody Derivatives as New Therapeutics for Hematologic Malignancies”
Clinical Trials & Observations
Crystal L. Mackall
View Articletitled, Introduction to the series of reviews on “Antibody Derivatives as New Therapeutics for Hematologic Malignancies”

INSIDE BLOOD COMMENTARIES

INSIDE BLOOD COMMENTARY
Sonic hedgehog causes mural cells to jump ‘n’ run
Stefan Liebner
View Articletitled, Sonic hedgehog causes mural cells to jump ‘n’ run
INSIDE BLOOD COMMENTARY
A WHIM satisfactorily addressed
Clinical Trials & Observations
Hal E. Broxmeyer
View Articletitled, A WHIM satisfactorily addressed
INSIDE BLOOD COMMENTARY
FV and APC resistance: the plot thickens
Elisabetta Castoldi
View Articletitled, FV and APC resistance: the plot thickens

BLOOD WORK

Cytomegalovirus-associated hemophagocytic lymphohistiocytosis in a patient with myasthenia gravis treated with azathioprine
John K. Frederiksen,Charles W. Ross
View Articletitled, Cytomegalovirus-associated hemophagocytic lymphohistiocytosis in a patient with myasthenia gravis treated with azathioprine
Cloaked in a starry sky
M. Kamran Mirza,Sandeep Gurbuxani
View Articletitled, Cloaked in a starry sky

REVIEW SERIES

Advances in the treatment of hematologic malignancies using immunoconjugates
Clinical Trials & Observations
Maria Corinna Palanca-Wessels,Oliver W. Press
View Articletitled, Advances in the treatment of hematologic malignancies using immunoconjugates

HOW I TREAT

How we treat sickle hepatopathy and liver transplantation in adults
Kate Gardner,Abid Suddle,Pauline Kane,John O’Grady,Nigel Heaton,Adrian Bomford,Swee Lay Thein
View Articletitled, How we treat sickle hepatopathy and liver transplantation in adults

CLINICAL TRIALS AND OBSERVATIONS

A phase 1 clinical trial of long-term, low-dose treatment of WHIM syndrome with the CXCR4 antagonist plerixafor
Clinical Trials & Observations
David H. McDermott,Qian Liu,Daniel Velez,Lizbeeth Lopez,Sandra Anaya-O’Brien,Jean Ulrick,Nana Kwatemaa,Judy Starling,Thomas A. Fleisher,Debra A. Long Priel,Melissa A. Merideth,Robert L. Giuntoli,Moses O. Evbuomwan,Patricia Littel,Martha M. Marquesen,Dianne Hilligoss,Rosamma DeCastro,George J. Grimes,Samuel T. Hwang,Stefania Pittaluga,Katherine R. Calvo,Pamela Stratton,Edward W. Cowen,Douglas B. Kuhns,Harry L. Malech,Philip M. Murphy
View Articletitled, A phase 1 clinical trial of long-term, low-dose treatment of WHIM syndrome with the CXCR4 antagonist plerixafor
Supplemental data
Long-term outcome with dasatinib after imatinib failure in chronic-phase chronic myeloid leukemia: follow-up of a phase 3 study
Clinical Trials & Observations
Neil P. Shah,François Guilhot,Jorge E. Cortes,Charles A. Schiffer,Philipp le Coutre,Tim H. Brümmendorf,Hagop M. Kantarjian,Andreas Hochhaus,Philippe Rousselot,Hesham Mohamed,Diane Healey,Michael Cunningham,Giuseppe Saglio
View Articletitled, Long-term outcome with dasatinib after imatinib failure in chronic-phase chronic myeloid leukemia: follow-up of a phase 3 study
Supplemental data
Pretransplant administration of imatinib for allo-HSCT in patients with BCR-ABL–positive acute lymphoblastic leukemia
Clinical Trials & Observations
Shuichi Mizuta,Keitaro Matsuo,Satoshi Nishiwaki,Kiyotoshi Imai,Heiwa Kanamori,Kazuteru Ohashi,Takahiro Fukuda,Yasushi Onishi,Koichi Miyamura,Satoshi Takahashi,Makoto Onizuka,Yoshiko Atsuta,Ritsuro Suzuki,Yasuo Morishima,Koji Kato,Hisashi Sakamaki,Junji Tanaka
View Articletitled, Pretransplant administration of imatinib for allo-HSCT in patients with <em>BCR-ABL</em><em>–</em>positive acute lymphoblastic leukemia
Predictive factors for the outcome of allogeneic transplantation in patients with MDS stratified according to the revised IPSS-R
Clinical Trials & Observations
Matteo G. Della Porta,Emilio Paolo Alessandrino,Andrea Bacigalupo,Maria Teresa van Lint,Luca Malcovati,Cristiana Pascutto,Michele Falda,Massimo Bernardi,Francesco Onida,Stefano Guidi,Anna Paola Iori,Raffaella Cerretti,Paola Marenco,Pietro Pioltelli,Emanuele Angelucci,Rosi Oneto,Francesco Ripamonti,Paolo Bernasconi,Alberto Bosi,Mario Cazzola,Alessandro Rambaldi,on behalf of Gruppo Italiano Trapianto di Midollo Osseo,on behalf of Gruppo Italiano Trapianto di Midollo Osseo,on behalf of Gruppo Italiano Trapianto di Midollo Osseo,on behalf of Gruppo Italiano Trapianto di Midollo Osseo,on behalf of Gruppo Italiano Trapianto di Midollo Osseo,on behalf of Gruppo Italiano Trapianto di Midollo Osseo,on behalf of Gruppo Italiano Trapianto di Midollo Osseo,on behalf of Gruppo Italiano Trapianto di Midollo Osseo,on behalf of Gruppo Italiano Trapianto di Midollo Osseo,on behalf of Gruppo Italiano Trapianto di Midollo Osseo,on behalf of Gruppo Italiano Trapianto di Midollo Osseo,on behalf of Gruppo Italiano Trapianto di Midollo Osseo,on behalf of Gruppo Italiano Trapianto di Midollo Osseo,on behalf of Gruppo Italiano Trapianto di Midollo Osseo,on behalf of Gruppo Italiano Trapianto di Midollo Osseo,on behalf of Gruppo Italiano Trapianto di Midollo Osseo,on behalf of Gruppo Italiano Trapianto di Midollo Osseo,on behalf of Gruppo Italiano Trapianto di Midollo Osseo,on behalf of Gruppo Italiano Trapianto di Midollo Osseo,on behalf of Gruppo Italiano Trapianto di Midollo Osseo,on behalf of Gruppo Italiano Trapianto di Midollo Osseo
View Articletitled, Predictive factors for the outcome of allogeneic transplantation in patients with MDS stratified according to the revised IPSS-R
Supplemental data

GENE THERAPY

Preclinical targeting of human acute myeloid leukemia and myeloablation using chimeric antigen receptor–modified T cells
Clinical Trials & Observations
Saar Gill,Sarah K. Tasian,Marco Ruella,Olga Shestova,Yong Li,David L. Porter,Martin Carroll,Gwenn Danet-Desnoyers,John Scholler,Stephan A. Grupp,Carl H. June,Michael Kalos
View Articletitled, Preclinical targeting of human acute myeloid leukemia and myeloablation using chimeric antigen receptor–modified T cells
Supplemental data

LYMPHOID NEOPLASIA

Targeting components of the alternative NHEJ pathway sensitizes KRAS mutant leukemic cells to chemotherapy
Patricia S. Hähnel,Birgit Enders,Daniel Sasca,Wynand P. Roos,Bernd Kaina,Lars Bullinger,Matthias Theobald,Thomas Kindler
View Articletitled, Targeting components of the alternative NHEJ pathway sensitizes KRAS mutant leukemic cells to chemotherapy
Supplemental data
NR4A1-mediated apoptosis suppresses lymphomagenesis and is associated with a favorable cancer-specific survival in patients with aggressive B-cell lymphomas
Alexander J. A. Deutsch,Beate Rinner,Kerstin Wenzl,Martin Pichler,Katharina Troppan,Elisabeth Steinbauer,Daniela Schwarzenbacher,Sonja Reitter,Julia Feichtinger,Sascha Tierling,Andreas Prokesch,Marcel Scheideler,Anne Krogsdam,Gerhard G. Thallinger,Helmut Schaider,Christine Beham-Schmid,Peter Neumeister
View Articletitled, NR4A1-mediated apoptosis suppresses lymphomagenesis and is associated with a favorable cancer-specific survival in patients with aggressive B-cell lymphomas
Supplemental data
Genetic lesions associated with chronic lymphocytic leukemia chemo-refractoriness
Monica Messina,Ilaria Del Giudice,Hossein Khiabanian,Davide Rossi,Sabina Chiaretti,Silvia Rasi,Valeria Spina,Antony B. Holmes,Marilisa Marinelli,Giulia Fabbri,Alfonso Piciocchi,Francesca R. Mauro,Anna Guarini,Gianluca Gaidano,Riccardo Dalla-Favera,Laura Pasqualucci,Raul Rabadan,Robin Foà
View Articletitled, Genetic lesions associated with chronic lymphocytic leukemia chemo-refractoriness
Supplemental data

MYELOID NEOPLASIA

Regulation of Trib2 by an E2F1-C/EBPα feedback loop in AML cell proliferation
Loveena Rishi,Maura Hannon,Mara Salomè,Marie Hasemann,Anne-Katrine Frank,Joana Campos,Jennifer Timoney,Caitriona O’Connor,Mary R. Cahill,Bo Porse,Karen Keeshan
View Articletitled, Regulation of Trib2 by an E2F1-C/EBPα feedback loop in AML cell proliferation
Supplemental data
IKK-dependent activation of NF-κB contributes to myeloid and lymphoid leukemogenesis by BCR-ABL1
Mo-Ying Hsieh,Richard A. Van Etten
View Articletitled, IKK-dependent activation of NF-κB contributes to myeloid and lymphoid leukemogenesis by BCR-ABL1
Supplemental data
Implications of the miR-10 family in chemotherapy response of NPM1-mutated AML
Brief Report
Violaine Havelange,Parvathi Ranganathan,Susan Geyer,Deedra Nicolet,Xiaomeng Huang,Xueyan Yu,Stefano Volinia,Steven M. Kornblau,Michael Andreeff,Carlo M. Croce,Guido Marcucci,Clara D. Bloomfield,Ramiro Garzon
View Articletitled, Implications of the miR-10 family in chemotherapy response of <em>NPM1</em>-mutated AML
Supplemental data
CALR exon 9 mutations are somatically acquired events in familial cases of essential thrombocythemia or primary myelofibrosis
Brief Report
Elisa Rumi,Ashot S. Harutyunyan,Daniela Pietra,Jelena D. Milosevic,Ilaria C. Casetti,Marta Bellini,Nicole C. C. Them,Chiara Cavalloni,Virginia V. Ferretti,Chiara Milanesi,Tiina Berg,Emanuela Sant’Antonio,Emanuela Boveri,Cristiana Pascutto,Cesare Astori,Robert Kralovics,Mario Cazzola,on behalf of the Associazione Italiana per la Ricerca sul Cancro Gruppo Italiano Malattie Mieloproliferative Investigators,on behalf of the Associazione Italiana per la Ricerca sul Cancro Gruppo Italiano Malattie Mieloproliferative Investigators,on behalf of the Associazione Italiana per la Ricerca sul Cancro Gruppo Italiano Malattie Mieloproliferative Investigators,on behalf of the Associazione Italiana per la Ricerca sul Cancro Gruppo Italiano Malattie Mieloproliferative Investigators,on behalf of the Associazione Italiana per la Ricerca sul Cancro Gruppo Italiano Malattie Mieloproliferative Investigators,on behalf of the Associazione Italiana per la Ricerca sul Cancro Gruppo Italiano Malattie Mieloproliferative Investigators,on behalf of the Associazione Italiana per la Ricerca sul Cancro Gruppo Italiano Malattie Mieloproliferative Investigators,on behalf of the Associazione Italiana per la Ricerca sul Cancro Gruppo Italiano Malattie Mieloproliferative Investigators,on behalf of the Associazione Italiana per la Ricerca sul Cancro Gruppo Italiano Malattie Mieloproliferative Investigators,on behalf of the Associazione Italiana per la Ricerca sul Cancro Gruppo Italiano Malattie Mieloproliferative Investigators,on behalf of the Associazione Italiana per la Ricerca sul Cancro Gruppo Italiano Malattie Mieloproliferative Investigators,on behalf of the Associazione Italiana per la Ricerca sul Cancro Gruppo Italiano Malattie Mieloproliferative Investigators,on behalf of the Associazione Italiana per la Ricerca sul Cancro Gruppo Italiano Malattie Mieloproliferative Investigators,on behalf of the Associazione Italiana per la Ricerca sul Cancro Gruppo Italiano Malattie Mieloproliferative Investigators,on behalf of the Associazione Italiana per la Ricerca sul Cancro Gruppo Italiano Malattie Mieloproliferative Investigators,on behalf of the Associazione Italiana per la Ricerca sul Cancro Gruppo Italiano Malattie Mieloproliferative Investigators,on behalf of the Associazione Italiana per la Ricerca sul Cancro Gruppo Italiano Malattie Mieloproliferative Investigators
View Articletitled, <em>CALR</em> exon 9 mutations are somatically acquired events in familial cases of essential thrombocythemia or primary myelofibrosis
Supplemental data

THROMBOSIS AND HEMOSTASIS

Novel FV mutation (W1920R, FVNara) associated with serious deep vein thrombosis and more potent APC resistance relative to FVLeiden
Keiji Nogami,Keiko Shinozawa,Kenichi Ogiwara,Tomoko Matsumoto,Kagehiro Amano,Katsuyuki Fukutake,Midori Shima
View Articletitled, Novel FV mutation (W1920R, FV<sub>Nara</sub>) associated with serious deep vein thrombosis and more potent APC resistance relative to FV<sub>Leiden</sub>

VASCULAR BIOLOGY

Sonic hedgehog mediates a novel pathway of PDGF-BB–dependent vessel maturation
Qinyu Yao,Marie-Ange Renault,Candice Chapouly,Soizic Vandierdonck,Isabelle Belloc,Béatrice Jaspard-Vinassa,Jean-Marie Daniel-Lamazière,Muriel Laffargue,Aksam Merched,Claude Desgranges,Alain-Pierre Gadeau
View Articletitled, Sonic hedgehog mediates a novel pathway of PDGF-BB–dependent vessel maturation
Supplemental data
All Issues

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