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Clinical significance of CD56 expression in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline-based regimens
Limited clinical relevance of imaging techniques in the follow-up of patients with advanced chronic lymphocytic leukemia: results of a meta-analysis
Comparison of treatment strategies for patients with intestinal diffuse large B-cell lymphoma: surgical resection followed by chemotherapy versus chemotherapy alone
Translocation t(14;16) and multiple myeloma: is it really an independent prognostic factor?
Efficacy of L-asparaginase with methotrexate and dexamethasone (AspaMetDex regimen) in patients with refractory or relapsing extranodal NK/T-cell lymphoma, a phase 2 study
Predictive factors for outcome and response in patients treated with second-generation tyrosine kinase inhibitors for chronic myeloid leukemia in chronic phase after imatinib failure
A phase 2 study of high-dose lenalidomide as initial therapy for older patients with acute myeloid leukemia
Pathophysiology of sickle cell disease is mirrored by the red blood cell metabolome
Issue Archive
February 10 2011
In this Issue
Table of Contents
Inside blood
Perspectives
Review Article
Clinical Trials and Observations
Clinical significance of CD56 expression in patients with acute promyelocytic leukemia treated with all-trans retinoic acid and anthracycline-based regimens
Clinical Trials & Observations
Pau Montesinos,Chelo Rayón,Edo Vellenga,Salut Brunet,José González,Marcos González,Aleksandra Holowiecka,Jordi Esteve,Juan Bergua,José D. González,Concha Rivas,Mar Tormo,Vicente Rubio,Javier Bueno,Félix Manso,Gustavo Milone,Javier de la Serna,Inmaculada Pérez,Manuel Pérez-Encinas,Isabel Krsnik,Josep M. Ribera,Lourdes Escoda,Bob Lowenberg,Miguel A. Sanz,on behalf of the PETHEMA and HOVON Groups
Limited clinical relevance of imaging techniques in the follow-up of patients with advanced chronic lymphocytic leukemia: results of a meta-analysis
Clinical Trials & Observations
Barbara F. Eichhorst,Kirsten Fischer,Anna-Maria Fink,Thomas Elter,Clemens M. Wendtner,Valentin Goede,Manuela Bergmann,Stephan Stilgenbauer,Georg Hopfinger,Matthias Ritgen,Jasmin Bahlo,Raymonde Busch,Michael Hallek,for the German CLL Study Group (GCLLSG)
Comparison of treatment strategies for patients with intestinal diffuse large B-cell lymphoma: surgical resection followed by chemotherapy versus chemotherapy alone
Clinical Trials & Observations
Seok Jin Kim,Hye Jin Kang,Jin Seok Kim,Sung Yong Oh,Chul Won Choi,Soon Il Lee,Jong Ho Won,Min Kyoung Kim,Jung Hye Kwon,Yeung-Chul Mun,Jae-Yong Kwak,Jung Mi Kwon,In Gyu Hwang,Hyo Jung Kim,Jinny Park,Sukjoong Oh,Jooryung Huh,Young Hyeh Ko,Cheolwon Suh,Won Seog Kim
Translocation t(14;16) and multiple myeloma: is it really an independent prognostic factor?
Brief Report
Hervé Avet-Loiseau,Florent Malard,Loic Campion,Florence Magrangeas,Catherine Sebban,Bruno Lioure,Olivier Decaux,Thierry Lamy,Laurence Legros,Jean-Gabriel Fuzibet,Mauricette Michallet,Bernadette Corront,Pascal Lenain,Cyrille Hulin,Claire Mathiot,Michel Attal,Thierry Facon,Jean-Luc Harousseau,Stephane Minvielle,Philippe Moreau,for the Intergroupe Francophone du Myélome
Hematopoiesis and Stem Cells
Immunobiology
Lymphoid Neoplasia
Efficacy of L-asparaginase with methotrexate and dexamethasone (AspaMetDex regimen) in patients with refractory or relapsing extranodal NK/T-cell lymphoma, a phase 2 study
Clinical Trials & Observations
Arnaud Jaccard,Nathalie Gachard,Benoit Marin,Sylvie Rogez,Marie Audrain,Felipe Suarez,Hervé Tilly,Franck Morschhauser,Catherine Thieblemont,Loic Ysebaert,Alain Devidas,Barbara Petit,Laurence de Leval,Philippe Gaulard,Jean Feuillard,Dominique Bordessoule,Olivier Hermine,for the GELA and GOELAMS Intergroup
Genome-wide association study identifies a novel susceptibility locus at 6p21.3 among familial CLL
Susan L. Slager,Kari G. Rabe,Sara J. Achenbach,Celine M. Vachon,Lynn R. Goldin,Sara S. Strom,Mark C. Lanasa,Logan G. Spector,Laura Z. Rassenti,Jose F. Leis,Nicola J. Camp,Martha Glenn,Neil E. Kay,Julie M. Cunningham,Curtis A. Hanson,Gerald E. Marti,J. Brice Weinberg,Vicki A. Morrison,Brian K. Link,Timothy G. Call,Neil E. Caporaso,James R. Cerhan
CP-690,550, a therapeutic agent, inhibits cytokine-mediated Jak3 activation and proliferation of T cells from patients with ATL and HAM/TSP
Wei Ju,Meili Zhang,Jian-kang Jiang,Craig J. Thomas,Unsong Oh,Bonita R. Bryant,Jing Chen,Noriko Sato,Yutaka Tagaya,John C. Morris,John E. Janik,Steven Jacobson,Thomas A. Waldmann
A small-molecule inhibitor of D-cyclin transactivation displays preclinical efficacy in myeloma and leukemia via phosphoinositide 3-kinase pathway
Xinliang Mao,Biyin Cao,Tabitha E. Wood,Rose Hurren,Jiefei Tong,Xiaoming Wang,Wenjie Wang,Jie Li,Yueping Jin,Wenxian Sun,Paul A. Spagnuolo,Neil MacLean,Michael F. Moran,Alessandro Datti,Jeffery Wrana,Robert A. Batey,Aaron D. Schimmer
Mutated RAS and constitutively activated Akt delineate distinct oncogenic pathways, which independently contribute to multiple myeloma cell survival
Torsten Steinbrunn,Thorsten Stühmer,Stefan Gattenlöhner,Andreas Rosenwald,Anja Mottok,Christian Unzicker,Hermann Einsele,Manik Chatterjee,Ralf C. Bargou
Myeloid Neoplasia
Predictive factors for outcome and response in patients treated with second-generation tyrosine kinase inhibitors for chronic myeloid leukemia in chronic phase after imatinib failure
Clinical Trials & Observations
Elias Jabbour,Hagop Kantarjian,Susan O'Brien,Jenny Shan,Guillermo Garcia-Manero,William Wierda,Farhad Ravandi,Gautam Borthakur,Mary Beth Rios,Jorge Cortes
A phase 2 study of high-dose lenalidomide as initial therapy for older patients with acute myeloid leukemia
Clinical Trials & Observations
Todd A. Fehniger,Geoffrey L. Uy,Kathryn Trinkaus,Alissa D. Nelson,Jeffery Demland,Camille N. Abboud,Amanda F. Cashen,Keith E. Stockerl-Goldstein,Peter Westervelt,John F. DiPersio,Ravi Vij
Mast cell hyperplasia, B-cell malignancy, and intestinal inflammation in mice with conditional expression of a constitutively active kit
Alexander Gerbaulet,Claudia Wickenhauser,Julia Scholten,Katrin Peschke,Sebastian Drube,Hans-Peter Horny,Thomas Kamradt,Ronald Naumann,Werner Müller,Thomas Krieg,Claudia Waskow,Karin Hartmann,Axel Roers
Phagocytes, Granulocytes, and Myelopoiesis
Esterified eicosanoids are acutely generated by 5-lipoxygenase in primary human neutrophils and in human and murine infection
Stephen R. Clark,Christopher J. Guy,Martin J. Scurr,Philip R Taylor,Ann P. Kift-Morgan,Victoria J. Hammond,Christopher P. Thomas,Barbara Coles,Gareth W. Roberts,Matthias Eberl,Simon A. Jones,Nicholas Topley,Sailesh Kotecha,Valerie B. O'Donnell
Platelets and Thrombopoiesis
Red Cells, Iron, and Erythropoiesis
Pathophysiology of sickle cell disease is mirrored by the red blood cell metabolome
e-blood
Dhouha Darghouth,Bérengère Koehl,Geoffrey Madalinski,Jean-François Heilier,Petra Bovee,Ying Xu,Marie-Françoise Olivier,Pablo Bartolucci,Malika Benkerrou,Serge Pissard,Yves Colin,Frederic Galacteros,Giel Bosman,Christophe Junot,Paul-Henri Roméo
Thrombosis and Hemostasis
Correspondence
Errata
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Cover Image
Cover Image
![issue cover]()
To visualize in vivo osteoclastogenesis, distal femur histologic sections were stained for tartrate-resistant acid phosphatase (TRACP). Shown are photomicrographs from a littermate control (top panel) and a mouse with a deletion of the Shwachman-Bodian-Diamond syndrome (Sbds) gene in osteoclast progenitor cells (bottom panel). Sbds-null mice exhibited a significant impairment in in vivo osteoclastogenesis, as evidenced by reduced numbers and sizes of the TRACP-positive red-stained multinucleated cells. See the article by Leung et al on page 2044.
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