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Journal Articles

A Phase (ph) 1b/2 Study of TAK-659, an Investigational Dual FLT-3 and SYK Inhibitor, in Patients (Pts) with Relapsed or Refractory Acute Myelogenous Leukemia (R/R AML)

Keith Pratz, MD, Mark J. Levis, MD, John C Morris, MD, Trisha Wise-Draper, MD PhD, Moshe Levy, MD, Dale L. Bixby, Patrick Burke, MD, Daniela Hernandez, MD, Kate Stumpo, BA, Karuppiah Kannan, Emily Sheldon-Waniga, PhD, Shining Wang, MD, Steven Zhang, PhD, Yaping Shou, MD PhD, Jessica K. Altman, MD, Jason Kaplan, MD, Olga Frankfurt, MD

Blood (2017) 130 (Supplement 1): 2622.

https://doi.org/10.1182/blood.V130.Suppl_1.2622.2622

Published: 2017

Journal Articles

a Phase 1b/2 Study of TAK-659, an Investigational Dual SYK and FLT-3 Inhibitor, in Patients (Pts) with Relapsed or Refractory Acute Myelogenous Leukemia (R/R AML)

Jason B Kaplan, MD, Dale L. Bixby, MD, John C Morris, MD, Olga Frankfurt, MD, Jessica Altman, Trisha Wise-Draper, MD PhD, Patrick W. Burke, MD, Sabrina Collins, BS, Karuppiah Kannan, PhD, Ling Wang, PhD, Stephanie Faucette, PharmD, PhD, Benjamin Lee, MD PhD, Yaping Shou, MD PhD, Mark J. Levis, MD PhD, Keith W. Pratz, MD

Blood (2016) 128 (22): 2834.

https://doi.org/10.1182/blood.V128.22.2834.2834

Published: 2016

Journal Articles

Markedly additive antitumor activity with the combination of a selective survivin suppressant YM155 and alemtuzumab in adult T-cell leukemia

Jing Chen, Cynthia A. Pise-Masison, Joanna H. Shih, John C. Morris, John E. Janik, Kevin C. Conlon, Anne Keating, Thomas A. Waldmann

Blood (2013) 121 (11): 2029–2037.

https://doi.org/10.1182/blood-2012-05-427773

Published: 2013

Includes: Supplemental data

Journal Articles

Phase 1 trial of IL-15 trans presentation blockade using humanized Mik-Beta-1 mAb in patients with T-cell large granular lymphocytic leukemia

Thomas A. Waldmann, Kevin C. Conlon, Donn M. Stewart, TatYana A. Worthy, John E. Janik, Thomas A. Fleisher, Paul S. Albert, William D. Figg, Shawn D. Spencer, Mark Raffeld, Jean R. Decker, Carolyn K. Goldman, Bonita R. Bryant, Michael N. Petrus, Stephen P. Creekmore, John C. Morris

Blood (2013) 121 (3): 476–484.

https://doi.org/10.1182/blood-2012-08-450585

Published: 2013

Includes: Supplemental data

Journal Articles

Radiation therapy for the management of patients with HTLV-1–associated adult T-cell leukemia/lymphoma

Charles B. Simone, II, John C. Morris, Donn M. Stewart, Nicole E. Urquhart, John E. Janik, Robert J. Kreitman, Elena Lita, Kevin Conlon, Gilian Wharfe, Thomas A. Waldmann, Aradhana Kaushal

Blood (2012) 120 (9): 1816–1819.

https://doi.org/10.1182/blood-2012-01-401349

Published: 2012

Journal Articles

Increased serum soluble IL-15Rα levels in T-cell large granular lymphocyte leukemia

Jing Chen, Mike Petrus, Richard Bamford, Joanna H. Shih, John C. Morris, John E. Janik, Thomas A. Waldmann

Blood (2012) 119 (1): 137–143.

https://doi.org/10.1182/blood-2011-04-346759

Published: 2012

Includes: Supplemental data

Journal Articles

Yttrium-90 Radiolabeled Daclizumab, An Anti-CD25 Monoclonal Antibody, Provides Effective Therapy for Refractory and Relapsed Hodgkin's Lymphoma,

Blood (2011) 118 (21): 3706.

https://doi.org/10.1182/blood.V118.21.3706.3706

Published: 2011

Journal Articles

CP-690,550, a therapeutic agent, inhibits cytokine-mediated Jak3 activation and proliferation of T cells from patients with ATL and HAM/TSP

Wei Ju, Meili Zhang, Jian-kang Jiang, Craig J. Thomas, Unsong Oh, Bonita R. Bryant, Jing Chen, Noriko Sato, Yutaka Tagaya, John C. Morris, John E. Janik, Steven Jacobson, Thomas A. Waldmann

Blood (2011) 117 (6): 1938–1946.

https://doi.org/10.1182/blood-2010-09-305425

Published: 2011

Includes: Supplemental data

Journal Articles

Autocrine/paracrine cytokine stimulation of leukemic cell proliferation in smoldering and chronic adult T-cell leukemia

Jing Chen, Mike Petrus, Bonita R. Bryant, Vinh Phuc Nguyen, Carolyn K. Goldman, Richard Bamford, John C. Morris, John E. Janik, Thomas A. Waldmann

Blood (2010) 116 (26): 5948–5956.

https://doi.org/10.1182/blood-2010-04-277418

Published: 2010

Journal Articles

Gene expression profiling of ATL patients: compilation of disease-related genes and evidence for TCF4 involvement in BIRC5 gene expression and cell viability

Cynthia A. Pise-Masison, Michael Radonovich, Kathleen Dohoney, John C. Morris, Deirdre O'Mahony, Min-Jung Lee, Jane Trepel, Thomas A. Waldmann, John E. Janik, John N. Brady

Blood (2009) 113 (17): 4016–4026.

https://doi.org/10.1182/blood-2008-08-175901

Published: 2009

Includes: Supplemental data

Journal Articles

Alemtuzumab (Campath 1-H) in Patients with HTLV-1 Associated Adult T-Cell Leukemia/Lymphoma.

Kamal Sharma, DO, John E. Janik, MD, Deirdre O’Mahony, MD, Donn Stewart, MD, Stefania Pittaluga, MD, Maryalice Stetler-Stevenson, MD, PhD, Elaine S. Jaffe, MD, Mark Raffeld, MD, Thomas A. Fleisher, MD, Cathryn C. Lee, NP, Nicole Urquhart, MD, Seth Steinberg, PhD, Thomas A. Waldmann, MD, John C. Morris, MD

Blood (2008) 112 (11): 2010.

https://doi.org/10.1182/blood.V112.11.2010.2010

Published: 2008

Journal Articles

Yttrium-90 Radiolabeled Humanized Monoclonal Antibody to CD25 in Refractory and Relapsed Hodgkin’s Lymphoma

Deirdre O’Mahony, MD, John E Janik, MD, Jorge A. Carrasquillo, MD, Pamela Seam, MD, Joseph A Fiorillo, MD, Donn Stewart, MD, Chang H Paik, PhD, Suzanne Fioravanti, RN, Millie Whatley, RNMT, Stefania Pittaluga, MD, PhD, Martin W Brechbiel, PhD, John C Morris, MD, Thomas A Waldmann, MD

Blood (2008) 112 (11): 231.

https://doi.org/10.1182/blood.V112.11.231.231

Published: 2008

Journal Articles

Induction of the IL-9 gene by HTLV-I Tax stimulates the spontaneous proliferation of primary adult T-cell leukemia cells by a paracrine mechanism

Jing Chen, Mike Petrus, Bonita R. Bryant, Vinh Phuc Nguyen, Mindy Stamer, Carolyn K. Goldman, Richard Bamford, John C. Morris, John E. Janik, Thomas A. Waldmann

Blood (2008) 111 (10): 5163–5172.

https://doi.org/10.1182/blood-2007-09-113654

Published: 2008

Journal Articles

EBV-Related Lymphoproliferative Disease Complicating Therapy with Siplizumab, a Novel Anti-CD2 Mediated T- and NK-Cell Depleting Agent, in Patients with T-Cell Malignancies.

Deirdre O’Mahony, MD, John C. Morris, MD, Maryalice Stetler-Stevenson, MD, Helen Matthews, RN, Stefania Pittaluga, MD, Paul Albert, PhD, Karen Kaucic, MD, Luz Hammershaimb, MD, Thomas A. Waldmann, MD, John E. Janik, MD

Blood (2007) 110 (11): 3565.

https://doi.org/10.1182/blood.V110.11.3565.3565

Published: 2007

Journal Articles

Phase I Trial of Siplizumab in CD2-Positive Lymphoproliferative Disease.

Deirdre O’Mahony, MD, John C. Morris, MD, Leslie Moses, Diana O’Hagan, Wendy Gao, Maryalice Stetler-Stevenson, MD, Margaret Taylor, Luz Hammershaimb, MD, Thomas A. Waldmann, John E. Janik, MD

Blood (2005) 106 (11): 3353.

https://doi.org/10.1182/blood.V106.11.3353.3353

Published: 2005

Journal Articles

Interaction of Measles Virus Vectors with Auger Electron Emitting Radioisotopes.

David Dingli, MD, PhD, Kah-Whye Peng, PhD, Mary E. Harvey, Sompong Vongpunsawad, Elizabeth R. Bergert, Robert A. Kyle, MD, Roberto Cattaneo, PhD, John C. Morris, MD, Stephen J. Russell, MD, PhD

Blood (2005) 106 (11): 5525.

https://doi.org/10.1182/blood.V106.11.5525.5525

Published: 2005

Journal Articles

Elevated serum-soluble interleukin-2 receptor levels in patients with anaplastic large cell lymphoma

John E. Janik, John C. Morris, Stefania Pittaluga, Kristin McDonald, Mark Raffeld, Elaine S. Jaffe, Nicole Grant, Martin Gutierrez, Thomas A. Waldmann, Wyndham H. Wilson

Blood (2004) 104 (10): 3355–3357.

https://doi.org/10.1182/blood-2003-11-3922

Published: 2004

Journal Articles

Image-guided radiovirotherapy for multiple myeloma using a recombinant measles virus expressing the thyroidal sodium iodide symporter

David Dingli, Kah-Whye Peng, Mary E. Harvey, Philip R. Greipp, Michael K. O'Connor, Roberto Cattaneo, John C. Morris, Stephen J. Russell

Blood (2004) 103 (5): 1641–1646.

https://doi.org/10.1182/blood-2003-07-2233

Published: 2004

Journal Articles

Genetically targeted radiotherapy for multiple myeloma

David Dingli, Rosa Maria Diaz, Elizabeth R. Bergert, Michael K. O'Connor, John C. Morris, Stephen J. Russell

Blood (2003) 102 (2): 489–496.

https://doi.org/10.1182/blood-2002-11-3390

Published: 2003

NARROW

A Phase (ph) 1b/2 Study of TAK-659, an Investigational Dual FLT-3 and SYK Inhibitor, in Patients (Pts) with Relapsed or Refractory Acute Myelogenous Leukemia (R/R AML)

a Phase 1b/2 Study of TAK-659, an Investigational Dual SYK and FLT-3 Inhibitor, in Patients (Pts) with Relapsed or Refractory Acute Myelogenous Leukemia (R/R AML)

Markedly additive antitumor activity with the combination of a selective survivin suppressant YM155 and alemtuzumab in adult T-cell leukemia

Phase 1 trial of IL-15 trans presentation blockade using humanized Mik-Beta-1 mAb in patients with T-cell large granular lymphocytic leukemia

Radiation therapy for the management of patients with HTLV-1–associated adult T-cell leukemia/lymphoma

Increased serum soluble IL-15Rα levels in T-cell large granular lymphocyte leukemia

Yttrium-90 Radiolabeled Daclizumab, An Anti-CD25 Monoclonal Antibody, Provides Effective Therapy for Refractory and Relapsed Hodgkin's Lymphoma,

CP-690,550, a therapeutic agent, inhibits cytokine-mediated Jak3 activation and proliferation of T cells from patients with ATL and HAM/TSP

Autocrine/paracrine cytokine stimulation of leukemic cell proliferation in smoldering and chronic adult T-cell leukemia

Gene expression profiling of ATL patients: compilation of disease-related genes and evidence for TCF4 involvement in BIRC5 gene expression and cell viability

Alemtuzumab (Campath 1-H) in Patients with HTLV-1 Associated Adult T-Cell Leukemia/Lymphoma.

Yttrium-90 Radiolabeled Humanized Monoclonal Antibody to CD25 in Refractory and Relapsed Hodgkin’s Lymphoma

Induction of the IL-9 gene by HTLV-I Tax stimulates the spontaneous proliferation of primary adult T-cell leukemia cells by a paracrine mechanism

EBV-Related Lymphoproliferative Disease Complicating Therapy with Siplizumab, a Novel Anti-CD2 Mediated T- and NK-Cell Depleting Agent, in Patients with T-Cell Malignancies.

Phase I Trial of Siplizumab in CD2-Positive Lymphoproliferative Disease.

Interaction of Measles Virus Vectors with Auger Electron Emitting Radioisotopes.

Elevated serum-soluble interleukin-2 receptor levels in patients with anaplastic large cell lymphoma

Image-guided radiovirotherapy for multiple myeloma using a recombinant measles virus expressing the thyroidal sodium iodide symporter

Genetically targeted radiotherapy for multiple myeloma

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American Society of Hematology

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