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Journal Articles

High-dose melphalan treatment significantly increases mutational burden at relapse in multiple myeloma

Mehmet Kemal Samur, Marco Roncador, Anil Aktas Samur, Mariateresa Fulciniti, Abdul Hamid Bazarbachi, Raphael Szalat, Masood A. Shammas, Adam S. Sperling, Paul G. Richardson, Florence Magrangeas, Stephane Minvielle, Aurore Perrot, Jill Corre, Philippe Moreau, Anjan Thakurta, Giovanni Parmigiani, Kenneth C. Anderson, Hervé Avet-Loiseau, Nikhil C. Munshi

Blood (2023) 141 (14): 1724–1736.

https://doi.org/10.1182/blood.2022017094

Published: 2023

Includes: Supplemental data

Journal Articles

Presence of Extrachromosomal DNA (ecDNA) Impacts Both Progression Free and Overall Survival and Is an Independent Poor Prognostic Marker in Multiple Myeloma

Parth Shah, Anil Aktas-Samur, Mariateresa Fulciniti, Raphael Szalat, Masood A. Shammas, Paul G. Richardson, Florence Magrangeas, Stephane Minvielle, Aurore Perrot, Jill Corre, Philippe Moreau, Anjan Thakurta, Kenneth C. Anderson, Herve Avet-Loiseau, Nikhil C. Munshi, Mehmet K. Samur

Blood (2021) 138 (Supplement 1): 461.

https://doi.org/10.1182/blood-2021-151647

Published: 2021

Journal Articles

High-Dose Melphalan Significantly Increases Mutational Burden in Multiple Myeloma Cells at Relapse: Results from a Randomized Study in Multiple Myeloma

Mehmet K. Samur, PhD, Marco Roncador, MD MSc, Anil Aktas-Samur, PhD, Mariateresa Fulciniti, PhD, Abdul Hamid Bazarbachi, MD, Raphael Szalat, Masood A. Shammas, PhD, Adam S Sperling, MD PhD, Paul G. Richardson, MD, Florence Magrangeas, Stephane Minvielle, PhD, Anjan Thakurta, Aurore Perrot, Jill Corre, PharmD, PhD, Philippe Moreau, MD, Kenneth Anderson, MD, Giovanni Parmigiani, PhD, Herve Avet-Loiseau, Nikhil C. Munshi, MD

Blood (2020) 136 (Supplement 1): 4–5.

https://doi.org/10.1182/blood-2020-139014

Published: 2020

Journal Articles

The Landscape of Genome Wide Somatic Alterations Identifies a Good-Risk Group in Newly Diagnosed Multiple Myeloma

Mehmet Kemal Samur, PhD, Anil Aktas Samur, PhD, Tessa Han, Marco Roncador, MD MSc, Mariateresa Fulciniti, PhD, Raphael Szalat, Masood A. Shammas, PhD, Jill Corre, PharmD, PhD, Paul G. Richardson, MD, Florence Magrangeas, Stephane Minvielle, PhD, Philippe Moreau, MD, Michel Attal, MD PhD, Anjan Thakurta, Kenneth C. Anderson, MD, Giovanni Parmigiani, PhD, Herve Avet-Loiseau, MD PhD, Nikhil C. Munshi, MD

Blood (2019) 134 (Supplement_1): 3055.

https://doi.org/10.1182/blood-2019-128521

Published: 2019

Journal Articles

Dysregulated Mirnas after Uniform Treatment Predict Outcome of Newly-Diagnosed Multiple Myeloma

Tessa Han, Stephane Minvielle, PhD, Anil Aktas Samur, PhD, Mariateresa Fulciniti, PhD, Florence Magrangeas, PhD, Paul G. Richardson, MD, Philippe Moreau, MD, Michel Attal, MD PhD, Kenneth C. Anderson, MD, Hervé Avet-Loiseau, MD PhD, Giovanni Parmigiani, PhD, Mehmet Kemal Samur, PhD, Nikhil C. Munshi, MD

Blood (2019) 134 (Supplement_1): 4348.

https://doi.org/10.1182/blood-2019-130343

Published: 2019

Journal Articles

Deciphering the Chronology of Copy Number Alterations in Multiple Myeloma (MM): What Comes First?

Anil Aktas Samur, PhD, Mehmet Kemal Samur, PhD, Stephane Minvielle, PhD, Florence Magrangeas, PhD, Masood A. Shammas, PhD, Mariateresa Fulciniti, PhD, Michel Attal, MD PhD, Philippe Moreau, Kenneth Anderson, MD, Giovanni Parmigiani, Hervé Avet-Loiseau, MD PhD, Nikhil Munshi, MD

Blood (2018) 132 (Supplement 1): 3171.

https://doi.org/10.1182/blood-2018-99-120101

Published: 2018

Journal Articles

Poor Prognosis Associated with Gains of CCND1 in Mantle Cell Lymphoma Treated By First Line Immuno-Chemotherapy — a Study By the Lysa Group

Blood (2018) 132 (Supplement 1): 4099.

https://doi.org/10.1182/blood-2018-99-113303

Published: 2018

Journal Articles

The Landscape of Structural Variant Signatures in Multiple Myeloma Identifies Distinct Disease Subgroups with Implications for Pathogenesis

Francesco Maura, Daniel Leongamornlert, BS, Nicos Angelopoulos, PhD, Kevin J Dawson, Mehmet Kemal Samur, PhD, Raphael Szalat, MD, Yu-Tzu Tai, PhD, Stephane Minvielle, PhD, Florence Magrangeas, Philippe Moreau, Paolo Corradini, MD, Kenneth C. Anderson, MD, Hervé Avet-Loiseau, MDPhD, Peter J. Campbell, PhD, Nikhil Munshi, MD, Niccolò Bolli

Blood (2018) 132 (Supplement 1): 109.

https://doi.org/10.1182/blood-2018-99-112420

Published: 2018

Journal Articles

Landscape of Recurrent Mutations in Non-Coding Genome with Functional Implications in Newly-Diagnosed Multiple Myeloma

Mehmet Kemal Samur, PhD, Chandraditya Chakraborty, PhD, Raphael Szalat, MD, Anil Aktas Samur, PhD, Mariateresa Fulciniti, PhD, Michael A Lopez, Masood A. Shammas, PhD, Paul Richardson, Florence Magrangeas, PhD, Stephane Minvielle, PhD, Philippe Moreau, Michel Attal, Anjan Thakurta, PhD, Kenneth Anderson, MD, Giovanni Parmigiani, Hervé Avet-Loiseau, MDPhD, Nikhil Munshi, MD

Blood (2018) 132 (Supplement 1): 190.

https://doi.org/10.1182/blood-2018-190

Published: 2018

Journal Articles

Correlations between p16 Protein Expression and Genomic Profile in Mantle Cell Lymphoma and Impact on Survival, a Lyma-Genomic Project Conducted on Behalf of the Lysa Group

Yannick LE Bris, MDPharmD, Danielle Canioni, MD, Barbara Burroni, MD, Anne Moreau, MD, Benoit Tessoulin, MD, Florence Magrangeas, PhD, Marie-Helene Delfau, MD, Catherine Thieblemont, MD, Lucie Oberic, MD, Krimo Bouabdallah, MD, Emmanuel Gyan, MD PhD, David Chiron, PhD, Catherine Pellat-deceunynck, PhD, Mary Callanan, PhD, Stephane Minvielle, PhD, Marie C Bene, PharmSci, PhD, Olivier Hermine, MD PhD, Steven Le Gouill, MD PhD

Blood (2018) 132 (Supplement 1): 2846.

https://doi.org/10.1182/blood-2018-99-113268

Published: 2018

Journal Articles

The Genomic Landscape of Multiple Myeloma Complex Structural Variations

Blood (2017) 130 (Supplement 1): 330.

https://doi.org/10.1182/blood.V130.Suppl_1.330.330

Published: 2017

Journal Articles

Clonality Analysis Reveals the Order of Acquisition of Copy Number Alterations in Multiple Myeloma

Anil Aktas Samur, PhD, Mehmet Kemal Samur, PhD, Stephane Minvielle, Florence Magrangeas, Yu-Tzu Tai, PhD, Mariateresa Fulciniti, PhD, Paul G Richardson, MD, Philippe Moreau, MDPhD, Kenneth C Anderson, MD, Michel Attal, MD PhD, Hervé Avet-Loiseau, Nikhil Munshi, MD

Blood (2017) 130 (Supplement 1): 1773.

https://doi.org/10.1182/blood.V130.Suppl_1.1773.1773

Published: 2017

Journal Articles

High-Resolution Whole-Genome Copy Number Profiling Identifies High-Risk and Low-Risk Patients with Mantle Cell Lymphoma, a Result of the Lyma-Genomic Project Conducted on Behalf the Lysa Group

Yannick Le Bris, PharmD, Florence Magrangeas, Olivier Hermine, MD PhD, David Chiron, PhD, Danielle Canioni, Anne Moreau, MD, Marie C Bene, PharmSciD, PhD, Loic Campion, Stephane Minvielle, Steven Le Gouill, MD PhD

Blood (2016) 128 (22): 1745.

https://doi.org/10.1182/blood.V128.22.1745.1745

Published: 2016

Journal Articles

Analysis of Mutational Signatures Suggest That Aid Has an Early and Driver Role in Multiple Myeloma

Blood (2016) 128 (22): 116.

https://doi.org/10.1182/blood.V128.22.116.116

Published: 2016

Journal Articles

A Detailed Alternate Splicing Landscape in Multiple Myeloma with Significant Potential Biological and Clinical Implications

Anil Aktas Samur, PhD, Mehmet Kemal Samur, PhD, Stephane Minvielle, PhD, Florence Magrangeas, Mariateresa Fulciniti, PhD, Raphael Szalat, Paul G. Richardson, MD, Kenneth C. Anderson, MD, Michel Attal, Philippe Moreau, Giovanni Parmigiani, PhD, Herve Avet-Loiseau, MD PhD, Nikhil C Munshi, MD

Blood (2016) 128 (22): 356.

https://doi.org/10.1182/blood.V128.22.356.356

Published: 2016

Journal Articles

Whole Genome Sequencing of Unique Paired SMM/MGUS Progressing to MM Samples Reveals a Genomic Landscape with Diverse Evolutionary Pattern

Blood (2016) 128 (22): 2088.

https://doi.org/10.1182/blood.V128.22.2088.2088

Published: 2016

Journal Articles

RNA-Seq De Novo Assembly of Clonal Immunoglobulin Rearrangements Identifies Interesting Biology and Uncovers Prognostic Features in Multiple Myeloma

David Mosen-Ansorena, PhD, Rachael Bashford-Rogers, PhD, Niccolo Bolli, MD, Stephane Minvielle, PhD, Florence Magrangeas, Kenneth C Anderson, MD, Herve Avet-Loiseau, MD PhD, Giovanni Parmigiani, PhD, Nikhil C Munshi, MD

Blood (2016) 128 (22): 195.

https://doi.org/10.1182/blood.V128.22.195.195

Published: 2016

Journal Articles

The Complex Landscape of Rearrangements in Smoldering and Symptomatic Multiple Myeloma Revealed By Whole-Genome Sequencing

Blood (2016) 128 (22): 236.

https://doi.org/10.1182/blood.V128.22.236.236

Published: 2016

Journal Articles

A Novel Evolutionary Pattern Revealed Using Deep Sequencing of Immunoglobulin Loci at Diagnosis and over the Course of Treatment in Multiple Myeloma Patients

Nikhil C. Munshi, MD, Joaquin Martinez-Lopez, Victoria Carlton, PhD, Stephanie Minvielle, Yu-Tzu Tai, PhD, Mariateresa Fulciniti, PhD, Mehmet K. Samur, PhD, Paul G. Richardson, MD, Michel Attal, Philippe Moreau, Florence Magrangeas, Kenneth C. Anderson, MD, Malek Faham, MD PhD, Herve Avet-Loiseau, MD PhD

Blood (2016) 128 (22): 238.

https://doi.org/10.1182/blood.V128.22.238.238

Published: 2016

Journal Articles

Understanding the role of hyperdiploidy in myeloma prognosis: which trisomies really matter?

Blood (2015) 126 (25): 2713–2719.

https://doi.org/10.1182/blood-2015-06-650242

Published: 2015

Includes: Supplemental data

NARROW

High-dose melphalan treatment significantly increases mutational burden at relapse in multiple myeloma

Presence of Extrachromosomal DNA (ecDNA) Impacts Both Progression Free and Overall Survival and Is an Independent Poor Prognostic Marker in Multiple Myeloma

High-Dose Melphalan Significantly Increases Mutational Burden in Multiple Myeloma Cells at Relapse: Results from a Randomized Study in Multiple Myeloma

The Landscape of Genome Wide Somatic Alterations Identifies a Good-Risk Group in Newly Diagnosed Multiple Myeloma

Dysregulated Mirnas after Uniform Treatment Predict Outcome of Newly-Diagnosed Multiple Myeloma

Deciphering the Chronology of Copy Number Alterations in Multiple Myeloma (MM): What Comes First?

Poor Prognosis Associated with Gains of CCND1 in Mantle Cell Lymphoma Treated By First Line Immuno-Chemotherapy — a Study By the Lysa Group

The Landscape of Structural Variant Signatures in Multiple Myeloma Identifies Distinct Disease Subgroups with Implications for Pathogenesis

Landscape of Recurrent Mutations in Non-Coding Genome with Functional Implications in Newly-Diagnosed Multiple Myeloma

Correlations between p16 Protein Expression and Genomic Profile in Mantle Cell Lymphoma and Impact on Survival, a Lyma-Genomic Project Conducted on Behalf of the Lysa Group

The Genomic Landscape of Multiple Myeloma Complex Structural Variations

Clonality Analysis Reveals the Order of Acquisition of Copy Number Alterations in Multiple Myeloma

High-Resolution Whole-Genome Copy Number Profiling Identifies High-Risk and Low-Risk Patients with Mantle Cell Lymphoma, a Result of the Lyma-Genomic Project Conducted on Behalf the Lysa Group

Analysis of Mutational Signatures Suggest That Aid Has an Early and Driver Role in Multiple Myeloma

A Detailed Alternate Splicing Landscape in Multiple Myeloma with Significant Potential Biological and Clinical Implications

Whole Genome Sequencing of Unique Paired SMM/MGUS Progressing to MM Samples Reveals a Genomic Landscape with Diverse Evolutionary Pattern

RNA-Seq De Novo Assembly of Clonal Immunoglobulin Rearrangements Identifies Interesting Biology and Uncovers Prognostic Features in Multiple Myeloma

The Complex Landscape of Rearrangements in Smoldering and Symptomatic Multiple Myeloma Revealed By Whole-Genome Sequencing

A Novel Evolutionary Pattern Revealed Using Deep Sequencing of Immunoglobulin Loci at Diagnosis and over the Course of Treatment in Multiple Myeloma Patients

Understanding the role of hyperdiploidy in myeloma prognosis: which trisomies really matter?

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American Society of Hematology

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American Society of Hematology

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