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Robert A. Batey
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Journal Articles

A small-molecule inhibitor of D-cyclin transactivation displays preclinical efficacy in myeloma and leukemia via phosphoinositide 3-kinase pathway

Xinliang Mao, Biyin Cao, Tabitha E. Wood, Rose Hurren, Jiefei Tong, Xiaoming Wang, Wenjie Wang, Jie Li, Yueping Jin, Wenxian Sun, Paul A. Spagnuolo, Neil MacLean, Michael F. Moran, Alessandro Datti, Jeffery Wrana, Robert A. Batey, Aaron D. Schimmer
Journal: Blood
Blood (2011) 117 (6): 1986–1997.
https://doi.org/10.1182/blood-2010-05-284810
Published: 2011
Includes: Supplemental data
Journal Articles

The antiparasitic agent ivermectin induces chloride-dependent membrane hyperpolarization and cell death in leukemia cells

Sumaiya Sharmeen, Marko Skrtic, Mahadeo A. Sukhai, Rose Hurren, Marcela Gronda, Xiaoming Wang, Sonali B. Fonseca, Hong Sun, Tabitha E. Wood, Richard Ward, Mark D. Minden, Robert A. Batey, Alessandro Datti, Jeff Wrana, Shana O. Kelley, Aaron D. Schimmer
Journal: Blood
Blood (2010) 116 (18): 3593–3603.
https://doi.org/10.1182/blood-2010-01-262675
Published: 2010
Includes: Supplemental data
Journal Articles

The ubiquitin-activating enzyme E1 as a therapeutic target for the treatment of leukemia and multiple myeloma

G. Wei Xu, Mohsin Ali, Tabitha E. Wood, Derek Wong, Neil Maclean, Xiaoming Wang, Marcela Gronda, Marko Skrtic, Xiaoming Li, Rose Hurren, Xinliang Mao, Meenakshi Venkatesan, Reza Beheshti Zavareh, Troy Ketela, John C. Reed, David Rose, Jason Moffat, Robert A. Batey, Sirano Dhe-Paganon, Aaron D. Schimmer
Journal: Blood
Blood (2010) 115 (11): 2251–2259.
https://doi.org/10.1182/blood-2009-07-231191
Published: 2010
Includes: Supplemental data
Journal Articles

The Novel Proteasome Inhibitor 5-Amino-8-Hydroxyquinole (5AHQ) Overcomes Bortezomib Resistance in Malignant Hematological Cell Line Models Harboring Mutations in the PSMB5 Gene.

Niels E Franke, MD, MSc, Johan van Meerloo, B.ASc, Linda Slot, MSc, Xiaoming Li, PhD, Tabitha E Wood, PhD, Katarina Vojtekova, MSc, Sue Ellen Verbrugge, MSc, Gertjan Kaspers, MD, PhD, Robert A. Batey, PhD, Aaron D. Schimmer, MD, PhD, Gerrit Jansen, PhD, Jacqueline Cloos, PhD
Journal: Blood
Blood (2009) 114 (22): 940.
https://doi.org/10.1182/blood.V114.22.940.940
Published: 2009
Journal Articles

Activation of Chloride Channels with the Anti-Parasitic Agent Ivermectin Induces Membrane Hyperpolarization and Cell Death in Leukemia Cells.

Sumaiya Sharmeen, BSc, Marko Skrtic, Mahadeo Sukhai, BSc, MSc, PhD, Joyce Sun, Rose Hurren, Marcela Gronda, Xiaoming Wang, Tabitha E Wood, PhD, Robert A. Batey, PhD, Sonali Fonesca, Shana Kelley, Alessandro Datti, Jeff Wrana, Aaron D. Schimmer, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 410.
https://doi.org/10.1182/blood.V114.22.410.410
Published: 2009
Journal Articles

A Small Molecule Inhibitor of D-Cyclin Transactivation Displays Preclinical Efficacy in Myeloma and Leukemia.

Xinliang Mao, MD, PhD, Tabitha E Wood, PhD, Rose Hurren, Jiefei Tong, PhD, Xiaoming Wang, Paul A. Spagnuolo, PhD, Neil MacLean, Michael F. Moran, PhD, Alessandro Datti, Jeff Wrana, PhD, Robert A. Batey, PhD, Aaron D. Schimmer, MD, PhD
Journal: Blood
Blood (2009) 114 (22): 2036.
https://doi.org/10.1182/blood.V114.22.2036.2036
Published: 2009
Journal Articles

Chelation of intracellular iron with the antifungal agent ciclopirox olamine induces cell death in leukemia and myeloma cells

Yanina Eberhard, Sean P. McDermott, Xiaoming Wang, Marcela Gronda, Amudha Venugopal, Tabitha E. Wood, Rose Hurren, Alessandro Datti, Robert A. Batey, Jeffrey Wrana, William E. Antholine, John E. Dick, Aaron D. Schimmer
Journal: Blood
Blood (2009) 114 (14): 3064–3073.
https://doi.org/10.1182/blood-2009-03-209965
Published: 2009
Includes: Supplemental data
Journal Articles

A Novel Chromene-Based Pan-PI3 Kinase Inhibitor Displays Preclinical Activity in Leukemia and Myeloma.

Xinliang Mao, MD, PhD, Tabitha W. Wood, PhD, Xiaoming Wang, PhD, Johnathan St-Germain, BSc, Michael F. Moran, PhD, Alessandro Datti, PhD, Jeff Wrana, PhD, Robert A. Batey, PhD, Aaron D. Schimmer, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 1605.
https://doi.org/10.1182/blood.V112.11.1605.1605
Published: 2008
Journal Articles

A Novel Non-Competitive Chemical Proteasome Inhibitor Displays Preclinical Activity in Myeloma and Leukemia.

Xiaoming Li, PhD, Tabitha E Wood, PhD, Remco Sprangers, PhD, Xinliang Mao, PhD, Xiaoming Wang, PhD, Yi Zhang, BSc, David Rose, PhD, Robert A. Batey, PhD, Lewis E. Kay, PhD, Aaron D. Schimmer, MD, PhD
Journal: Blood
Blood (2008) 112 (11): 1711.
https://doi.org/10.1182/blood.V112.11.1711.1711
Published: 2008