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Issue Archive

Volume 115, Issue 1
January 7 2010
Issue Cover

Table of Contents

INSIDE BLOOD

THROMBOSIS & HEMOSTASIS
Platelets: yin and yang
Peter N. Walsh
View Articletitled, Platelets: yin and yang
PLATELETS & THROMBOPOIESIS
Platelet RNA chips dip into thrombocytosis
Srikanth Nagalla,Paul F. Bray
View Articletitled, Platelet RNA chips dip into thrombocytosis
TRANSPLANTATION
A role for lymphotoxin in GVHD and GVL
Kenneth R. Cooke
View Articletitled, A role for lymphotoxin in GVHD and GVL

BLOOD WORK

Cutaneous adult T-cell lymphoma leukemia
View Articletitled, Cutaneous adult T-cell lymphoma leukemia

PLENARY PAPERS

Class prediction models of thrombocytosis using genetic biomarkers
Dmitri V. Gnatenko,Wei Zhu,Xiao Xu,Edward T. Samuel,Melissa Monaghan,Mohammad H. Zarrabi,Christi Kim,Anil Dhundale,Wadie F. Bahou
View Articletitled, Class prediction models of thrombocytosis using genetic biomarkers
Supplemental data

REVIEW ARTICLES

The new oral anticoagulants
David Garcia,Edward Libby,Mark A. Crowther
View Articletitled, The new oral anticoagulants

HOW I TREAT

How I treat hairy cell leukemia
Michael R. Grever
View Articletitled, How I treat hairy cell leukemia

CLINICAL TRIALS AND OBSERVATIONS

Combination immunosuppressant therapy for patients with chronic refractory immune thrombocytopenic purpura
Clinical Trials & Observations
Donald M. Arnold,Ishac Nazi,Aurelio Santos,Howard Chan,Nancy M. Heddle,Theodore E. Warkentin,John G. Kelton
View Articletitled, Combination immunosuppressant therapy for patients with chronic refractory immune thrombocytopenic purpura
Bortezomib and high-dose melphalan as conditioning regimen before autologous stem cell transplantation in patients with de novo multiple myeloma: a phase 2 study of the Intergroupe Francophone du Myélome (IFM)
Clinical Trials & Observations
Murielle Roussel,Philippe Moreau,Anne Huynh,Jean-Yves Mary,Clotaire Danho,Denis Caillot,Cyrille Hulin,Christophe Fruchart,Gérald Marit,Brigitte Pégourié,Pascal Lenain,Carla Araujo,Brigitte Kolb,Edouard Randriamalala,Bruno Royer,Anne-Marie Stoppa,Mammoun Dib,Véronique Dorvaux,Laurent Garderet,Claire Mathiot,Hervé Avet-Loiseau,Jean-Luc Harousseau,Michel Attal,for the Intergroupe Francophone du Myélome (IFM)
View Articletitled, Bortezomib and high-dose melphalan as conditioning regimen before autologous stem cell transplantation in patients with de novo multiple myeloma: a phase 2 study of the Intergroupe Francophone du Myélome (IFM)

HEMATOPOIESIS AND STEM CELLS

Loss-of-function Additional sex combs like 1 mutations disrupt hematopoiesis but do not cause severe myelodysplasia or leukemia
Cynthia L. Fisher,Nicolas Pineault,Christy Brookes,Cheryl D. Helgason,Hideaki Ohta,Caroline Bodner,Jay L. Hess,R. Keith Humphries,Hugh W. Brock
View Articletitled, Loss-of-function <em>Additional sex combs like 1</em> mutations disrupt hematopoiesis but do not cause severe myelodysplasia or leukemia
Supplemental data
W41/W41 blastocyst complementation: a system for genetic modeling of hematopoiesis
Brief Report
Lina Jansson,Jonas Larsson
View Articletitled, <em>W<sup>41</sup>/W<sup>41</sup></em> blastocyst complementation: a system for genetic modeling of hematopoiesis

LYMPHOID NEOPLASIA

Platelet-derived growth factor mediates survival of leukemic large granular lymphocytes via an autocrine regulatory pathway
Jun Yang,Xin Liu,Susan B. Nyland,Ranran Zhang,Lindsay K. Ryland,Kathleen Broeg,Kendall Thomas Baab,Nancy Ruth Jarbadan,Rosalyn Irby,Thomas P. Loughran, Jr
View Articletitled, Platelet-derived growth factor mediates survival of leukemic large granular lymphocytes via an autocrine regulatory pathway
Supplemental data
Identification of early growth response protein 1 (EGR-1) as a novel target for JUN-induced apoptosis in multiple myeloma
Lijuan Chen,Siqing Wang,Yiming Zhou,Xiaosong Wu,Igor Entin,Joshua Epstein,Shmuel Yaccoby,Wei Xiong,Bart Barlogie,John D. Shaughnessy, Jr,Fenghuang Zhan
View Articletitled, Identification of early growth response protein 1 (<em>EGR-1</em>) as a novel target for <em>JUN</em>-induced apoptosis in multiple myeloma
The normal IGHV1-69–derived B-cell repertoire contains stereotypic patterns characteristic of unmutated CLL
Francesco Forconi,Kathleen N. Potter,Isla Wheatley,Nikos Darzentas,Elisa Sozzi,Kostas Stamatopoulos,C. Ian Mockridge,Graham Packham,Freda K. Stevenson
View Articletitled, The normal <em>IGHV1-69</em>–derived B-cell repertoire contains stereotypic patterns characteristic of unmutated CLL
Supplemental data

MYELOID NEOPLASIA

Alpha-defensins secreted by dysplastic granulocytes inhibit the differentiation of monocytes in chronic myelomonocytic leukemia
Nathalie Droin,Arnaud Jacquel,Jean-Baptiste Hendra,Cindy Racoeur,Caroline Truntzer,Delphine Pecqueur,Naïma Benikhlef,Marion Ciudad,Leslie Guery,Valérie Jooste,Erick Dufour,Pierre Fenaux,Bruno Quesnel,Olivier Kosmider,Michaëla Fontenay,Patrick Ducoroy,Eric Solary
View Articletitled, Alpha-defensins secreted by dysplastic granulocytes inhibit the differentiation of monocytes in chronic myelomonocytic leukemia
Supplemental data
A prototype nonpeptidyl, hydrazone class, thrombopoietin receptor agonist, SB-559457, is toxic to primary human myeloid leukemia cells
Brief Report
Anna Kalota,Alan M. Gewirtz
View Articletitled, A prototype nonpeptidyl, hydrazone class, thrombopoietin receptor agonist, SB-559457, is toxic to primary human myeloid leukemia cells
Supplemental data

RED CELLS, IRON, AND ERYTHROPOIESIS

A genome-wide association analysis of serum iron concentrations
Brief Report
Toshiko Tanaka,Cindy N. Roy,Wenliang Yao,Amy Matteini,Richard D. Semba,Dan Arking,Jeremy D. Walston,Linda P. Fried,Andrew Singleton,Jack Guralnik,Gonçalo R. Abecasis,Stefania Bandinelli,Dan L. Longo,Luigi Ferrucci
View Articletitled, A genome-wide association analysis of serum iron concentrations
Supplemental data

THROMBOSIS AND HEMOSTASIS

Anticoagulant and antithrombotic properties of platelet protease nexin-1
Yacine Boulaftali,Frédéric Adam,Laurence Venisse,Véronique Ollivier,Benjamin Richard,Sabrina Taieb,Denis Monard,Rémi Favier,Marie-Christine Alessi,Marijke Bryckaert,Véronique Arocas,Martine Jandrot-Perrus,Marie-Christine Bouton
View Articletitled, Anticoagulant and antithrombotic properties of platelet protease nexin-1
Supplemental data

TRANSPLANTATION

Immunomodulatory effect of 5-azacytidine (5-azaC): potential role in the transplantation setting
Luis I. Sánchez-Abarca,Silvia Gutierrez-Cosio,Carlos Santamaría,Teresa Caballero-Velazquez,Belen Blanco,Carmen Herrero-Sánchez,Juan L. García,Soraya Carrancio,Pilar Hernández-Campo,Francisco J. González,Teresa Flores,Laura Ciudad,Esteban Ballestar,Consuelo del Cañizo,Jesus F. San Miguel,Jose A. Pérez-Simon
View Articletitled, Immunomodulatory effect of 5-azacytidine (5-azaC): potential role in the transplantation setting
Supplemental data
Soluble lymphotoxin is an important effector molecule in GVHD and GVL
Kate A. Markey,Angela C. Burman,Tatjana Banovic,Rachel D. Kuns,Neil C. Raffelt,Vanessa Rowe,Stuart D. Olver,Alistair L. J. Don,Edward S. Morris,Allison R. Pettit,Yana A. Wilson,Renee J. Robb,Louise M. Randall,Heinrich Korner,Christian R. Engwerda,Andrew D. Clouston,Kelli P. A. MacDonald,Geoffrey R. Hill
View Articletitled, Soluble lymphotoxin is an important effector molecule in GVHD and GVL

VASCULAR BIOLOGY

A noncoding antisense RNA in tie-1 locus regulates tie-1 function in vivo
Keguo Li,Yannick Blum,Anjali Verma,Zhong Liu,Kallal Pramanik,Noah R. Leigh,Chang Z. Chun,Ganesh V. Samant,Baofeng Zhao,Maija K. Garnaas,Mark A. Horswill,Stephen A. Stanhope,Paula E. North,Robert Q. Miao,George A. Wilkinson,Markus Affolter,Ramani Ramchandran
View Articletitled, A noncoding antisense RNA in <em>tie-1</em> locus regulates <em>tie-1</em> function in vivo
Supplemental data
Osteoclasts are important for bone angiogenesis
Frank C. Cackowski,Judith L. Anderson,Kenneth D. Patrene,Rushir J. Choksi,Steven D. Shapiro,Jolene J. Windle,Harry C. Blair,G. David Roodman
View Articletitled, Osteoclasts are important for bone angiogenesis

CORRESPONDENCE

WHO subvariants of indolent mastocytosis: clinical details and prognostic evaluation in 159 consecutive adults
Animesh Pardanani,Ken-Hong Lim,Terra L. Lasho,Christy M. Finke,Rebecca F. McClure,Chin-yang Li,Ayalew Tefferi
View Articletitled, WHO subvariants of indolent mastocytosis: clinical details and prognostic evaluation in 159 consecutive adults
Both permissive and nonpermissive HLA-DPB1 mismatches can induce polyclonal HLA-DPB1 specific immune responses in vivo and in vitro
Caroline E. Rutten,Simone A. P. van Luxemburg-Heijs,Edith D. van der Meijden,Marieke Griffioen,Machteld Oudshoorn,Roel Willemze,J. H. Frederik Falkenburg
View Articletitled, Both permissive and nonpermissive HLA-DPB1 mismatches can induce polyclonal HLA-DPB1 specific immune responses in vivo and in vitro

ERRATUM

Cohen. High-dose compared with intermediate-dose methotrexate in children with a first relapse of acute lymphatic leukemia. Blood. 2008;112(3):910.
View Articletitled, Cohen. High-dose compared with intermediate-dose methotrexate in children with a first relapse of acute lymphatic leukemia. <em>Blood</em>. 2008;112(3):910.
All Issues

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