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Christophe Fruchart
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Journal Articles

Treatment options, responses and outcome of 1220 classic Hodgkin lymphoma patients included in realysa, a prospective multicentric lysa cohort

Free
Herve Ghesquieres, Catherine Thieblemont, Aurelien Belot, Cecile Borel, Fanny Cherblanc, Jean Galtier, Alexia Torroja, Doriane Cavalieri, Alice Pauc, Bastien Lesne, Sandy Amorim, Alexandra Traverse Glehen, Barbara Burroni, Salim Kanoun, Anne Ségolène Cottereau, Nadine Morineau, Mohamed Touati, Adrien Chauchet, Fontanet Bijou, Sydney Dubois, Ludovic Fouillet, Christophe Fruchart, Thomas Gastinne, Sandra Leguyader Peyrou, Alain Monnereau, Luc-Matthieu Fornecker, Jehan Dupuis, Cedric Rossi
Journal: Blood
Blood (2025) 146 (Supplement 1): 1853.
https://doi.org/10.1182/blood-2025-1853
Published: 2025
Journal Articles

Comparison of axicabtagene ciloleucel to standard regimens as second line treatment for large B cell lymphoma in real life: A lysa study from descar-T and realysa registries

Free
Gabriel Brisou, Aurelien Belot, Emmanuel Bachy, Herve Ghesquieres, François-Xavier Gros, Krimo Bouabdallah, Guillaume Cartron, Roberta Di Blasi, Roch Houot, Cedric Rossi, Amandine Durand, Fabien Le Bras, Corinne Haioun, Thomas Gastinne, Remy Dulery, Pierre Bories, Fabrice Jardin, Blandine Guffroy, Luc-Matthieu Fornecker, Cristina Castilla-Llorente, Gandhi Damaj, Franck Morschhauser, Michael Loschi, Stephanie Guidez, Choquet Sylvain, Aline Schmidt, Laurianne Drieu La Rochelle, Marie-Thérèse Rubio, Sylvain Carras, Jacques-Olivier Bay, Adrien Chauchet, Magalie Joris, Ludovic Fouillet, Laure Lebras, Julie Abraham, Fontanet Bijou, Olivier Hermine, Antoine Bonnet, Justine Decroocq, Sandy Amorim, Nadine Morineau, Pauline Lionne, Sophie Dennetiere, Laura Herbreteau, Bernard Drenou, Launay Vincent, Gaelle Olivier, Gaëlle Labouré, Olivier Fitoussi, Christophe Fruchart, Cecile Leyronnas, Fanny Cherblanc, Elodie Gat, Benoit Tessoulin
Journal: Blood
Blood (2025) 146 (Supplement 1): 2764.
https://doi.org/10.1182/blood-2025-2764
Published: 2025
Journal Articles

Evaluation of levofloxacine as antibiotic prophylaxis in MDS and AML patients treated with azacitidine: Results from the randomized open-label phase III azabac study

Free
Juliette Pénichoux, Stephane Cheze, Wala Najar, Vincent Camus, Emilie Leveque, Fabrice Jardin, Stephane Lepretre, Sydney Dubois, Emilie Lemasle, Anne Menard, Marion David, Mustafa Alani, Nathalie Contentin, Florian Bouclet, Pascal Lenain, Oana Brehar, Camille Pouaty, Hélène Lanic, Pierre Lebreton, Alexandra Zduniak, Christophe Fruchart, Luminata Groza, Aspasia Stamatoulas Bastard
Journal: Blood
Blood (2025) 146 (Supplement 1): 3846.
https://doi.org/10.1182/blood-2025-3846
Published: 2025
Journal Articles

Combined PET and ctDNA response as a predictor of POD24 for follicular lymphoma after first-line induction treatment

Available to Purchase
Clinical Trials & Observations
Alexis Claudel, Anne-Ségolène Cottereau, Emmanuel Bachy, Emmanuel Itti, Pierre Feugier, Cedric Rossi, Francois Lemonnier, Vincent Camus, Nicolas Daguindau, Guillaume Cartron, Emmanuelle Nicolas-Virelizier, Diana-Laure Mboumba, Christophe Cardoso, Côme Bommier, Benoit Tessoulin, Christophe Fruchart, Adrien Gilbert, Eric Durot, Emmanuel Fleck, Gian Matteo Pica, Hacene Zerazhi, Stephanie Guidez, Morgane Cheminant, Clementine Sarkozy, Luc Xerri, Laetitia Vercellino, Nesrine Trabelsi, Lucie Gomes, Cedric Portugues, Pierre-Julien Viailly, Marie-Hélène Delfau-Larue, Franck Morschhauser
Journal: Blood
Blood (2025) 146 (8): 913–925.
https://doi.org/10.1182/blood.2024027727
Published: 2025
Includes: Supplemental data
Journal Articles

Combining PET/CT and Ctdna Assessments at 6 Months from Induction Treatment Better Predicts Outcome in Previously Untreated Patients with Follicular Lymphoma: A Relevance Ancillary Lysa Study

Free
Alexis Claudel, Anne Ségolène Cottereau, Emmanuel Bachy, Pierre Feugier, Rene-Olivier Casasnovas, Corinne Haioun, Herve Tilly, Nicolas Daguindau, Guillaume Cartron, Emmanuelle Nicolas Virelizier, Pauline Brice, Benoit Tessoulin, Christophe Fruchart, Sylvie Glaisner, Alain Jacques Delmer, Emmanuel Fleck, Gian Matteo Pica, Hacene Zerazhi, Stephanie Guidez, Morgane Cheminant, Luc Xerri, Laetitia Vercellino, Loïc Chartier, Lucie Gomes, Pierre-Julien Viailly, Marie-Helene Delfau, Franck Morschhauser
Journal: Blood
Blood (2023) 142 (Supplement 1): 170.
https://doi.org/10.1182/blood-2023-178030
Published: 2023
Journal Articles

Obinutuzumab plus lenalidomide in advanced, previously untreated follicular lymphoma in need of systemic therapy: a LYSA study

Free
Clinical Trials & Observations
Emmanuel Bachy, Roch Houot, Pierre Feugier, Krimo Bouabdallah, Reda Bouabdallah, Emmanuelle Nicolas Virelizier, Marie Maerevoet, Christophe Fruchart, Sylvia Snauwaert, Steven Le Gouill, Jean-Pierre Marolleau, Lysiane Molina, Cécile Moluçon-Chabrot, Catherine Thieblemont, Hervé Tilly, Fontanet Bijou, Corinne Haioun, Eric Van den Neste, Bettina Fabiani, Michel Meignan, Guillaume Cartron, Gilles Salles, Olivier Casasnovas, Franck Morschhauser
Journal: Blood
Blood (2022) 139 (15): 2338–2346.
https://doi.org/10.1182/blood.2021013526
Published: 2022
Includes: Supplemental data
Journal Articles

Six-Year Results from the Phase 3 Randomized Study Relevance Show Similar Outcomes for Previously Untreated Follicular Lymphoma Patients Receiving Lenalidomide Plus Rituximab (R 2 ) Versus Rituximab-Chemotherapy Followed By Rituximab Maintenance

Free
Franck Morschhauser, Loretta Nastoupil, Pierre Feugier, Jean Marc Schiano De Colella, Hervé Tilly, M. Lia Palomba, Emmanuel Bachy, Christophe Fruchart, Edward Libby, Rene-Olivier Casasnovas, Ian W. Flinn, Corinne Haioun, Herve Maisonneuve, Loic Ysebaert, Nancy L. Bartlett, Kamal Bouabdallah, Pauline Brice, Vincent Ribrag, Steven Le Gouill, Nicolas Daguindau, Vincent Delwail, Gian-Matteo Pica, Alejandro Martin Garcia-Sancho, Armando Lopez-Guillermo, Jean-Francois Larouche, Kiyoshi Ando, Gomes da Silva Maria, Marc André, Ka Lung Wu, Laurie H. Sehn, Koji Izutsu, Guillaume Cartron, Argyrios Gkasiamis, Russell Crowe, Luc Xerri, Nathan H. Fowler, Gilles Salles
Journal: Blood
Blood (2021) 138 (Supplement 1): 2417.
https://doi.org/10.1182/blood-2021-148218
Published: 2021
Journal Articles

High total metabolic tumor volume at baseline predicts survival independent of response to therapy

Free
CME Clinical Trials & Observations
Laetitia Vercellino, Anne-Segolene Cottereau, Olivier Casasnovas, Hervé Tilly, Pierre Feugier, Loic Chartier, Christophe Fruchart, Louise Roulin, Lucie Oberic, Gian Matteo Pica, Vincent Ribrag, Julie Abraham, Marc Simon, Hugo Gonzalez, Reda Bouabdallah, Olivier Fitoussi, Catherine Sebban, Armando López-Guillermo, Laurence Sanhes, Franck Morschhauser, Judith Trotman, Bernadette Corront, Bachra Choufi, Sylvia Snauwaert, Pascal Godmer, Josette Briere, Gilles Salles, Philippe Gaulard, Michel Meignan, Catherine Thieblemont
Journal: Blood
Blood (2020) 135 (16): 1396–1405.
https://doi.org/10.1182/blood.2019003526
Published: 2020
Includes: Supplemental data
Journal Articles

Validation of the PRIMA-Prognostic Index for Patients Treated with Rituximab Plus Chemotherapy and Refinement of Prognostic Parameters for Patients on Rituximab Plus Lenalidomide in the Phase III Relevance Trial

Free
Edith Julia, Nathan H Fowler, MD, Emmanuel Bachy, MD PhD, Pierre Feugier, MD PhD, Reda Bouabdallah, Herve Tilly, MD PhD, M. Lia Palomba, MD, Christophe Fruchart, MD, Edward N. Libby, III, MD, Rene-Olivier Casasnovas, MD, Ian W. Flinn, MD PhD, Corinne Haioun, MD PhD, Herve Maisonneuve, MD, Loic Ysebaert, MD PhD, Nancy L. Bartlett, MD, Kamal Bouabdallah, MD, Pauline Brice, Vincent Ribrag, MD, Nicolas Daguindau, MD, Steven Le Gouill, Gian-Matteo Pica, MD, Alejandro Martín, MD PhD, Armando Lopez-Guillermo, Jean-Francois Larouche, MD, Kiyoshi Ando, Gomes da Silva Maria, MD PhD, Marc André, Ka Lung Wu, MD, Laurie H Sehn, MD, Kensei Tobinai, MD PhD, Guillaume Cartron, Richard Delarue, Myron Czuczman, Luc Xerri, MD PhD, Gilles A. Salles, MD PhD, Franck Morschhauser, MD
Journal: Blood
Blood (2019) 134 (Supplement_1): 1524.
https://doi.org/10.1182/blood-2019-129024
Published: 2019
Journal Articles

A Phase II Lysa Study of Obinutuzumab Combined with Lenalidomide for Advanced Untretated Follicular B-Cell Lymphoma in Need of Systemic Therapy

Free
Franck Morschhauser, MD, Gilles Andre Salles, Rene-Olivier Casasnovas, MD, Pierre Feugier, Krimo Bouabdallah, MD, Guillaume Cartron, Reda Bouabdallah, MD, Emmanuelle Nicolas-Virelizier, MD, Marie Maerevoet, MD, Sylvia Snauwaert, Christophe Fruchart, Steven LE Gouill, MD PhD, Cécile Moluçon-Chabrot, MD PhD, Caroline Delette, Lysiane Molina, MD, Herve Tilly, MD, Catherine Thieblemont, MD, Eric Van Den Neste, Fontanet Bijou, MD, Bettina Fabiani, MD, Corinne Haioun, MD, Roch Houot, MD PhD
Journal: Blood
Blood (2018) 132 (Supplement 1): 446.
https://doi.org/10.1182/blood-2018-99-112805
Published: 2018
Journal Articles

Interim Results from an Ongoing Phase 2 Multicenter Study of Tazemetostat, an EZH2 Inhibitor, in Patients with Relapsed or Refractory (R/R) Diffuse Large B-Cell Lymphoma (DLBCL)

Free
Vincent Ribrag, Franck Morschhauser, Pamela McKay, MD, Gilles Andre Salles, Connie Lee Batlevi, MD, Anna Schmitt, Herve Tilly, MD, Guillaume Cartron, Catherine Thieblemont, MD, Christophe Fruchart, John G. Gribben, Thierry Lamy, Steven Le Gouill, Reda Bouabdallah, MD, Michael Dickinson, MD, Stephen Opat, Deyaa Adib, Stephen J Blakemore, John Larus, Peter Johnson, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4196.
https://doi.org/10.1182/blood-2018-99-113411
Published: 2018
Journal Articles

Impact of Total Metabolic Tumor Volume at Baseline in the Remarc Study

Free
Anne Ségolène Cottereau, Laetitia Vercellino, Olivier Casasnovas, MD, Herve Tilly, MD, Pierre Feugier, Christophe Fruchart, Louise Roulin, Lucie Oberic, MD, Gian Matteo Pica, MD, Vincent Ribrag, MD, Julie Abraham, MD, Marc Simon, MD, Hugo Gonzalez, Reda Bouabdallah, MD, Olivier Fitoussi, MD, Catherine Sebban, MD, Armando Lopez-Guillermo, Margaret Macro, Laurence Sahnes, Franck Morschhauser, MD, Judith Trotman, Bernadette Corront, Bachra Choufi, Sylvia Snauwaert, Pascal Godmer, Loïc Chartier, Gilles Salles, MD PhD, Josette Briere, MD, Bertrand Coiffier, MD PhD, Michel Meignan, Catherine Thieblemont, MD
Journal: Blood
Blood (2018) 132 (Supplement 1): 4199.
https://doi.org/10.1182/blood-2018-99-112874
Published: 2018
Journal Articles

Updated Report on Identification of Molecular Predictors of Tazemetostat Response in an Ongoing NHL Phase 2 Study

Free
Alice McDonald, Elizabeth Thomas, Scott Daigle, Franck Morschhauser, Gilles Salles, MD PhD, Vincent Ribrag, Pamela McKay, MD, Herve Tilly, MD, Anna Schmitt, Connie Lee Batlevi, MD, Christophe Fruchart, Peter Johnson, MD, Michael Dickinson, MD, Stephen Opat, Wojciech Jurczak, Guillaume Cartron, Thierry Lamy, Pier Luigi Zinzani, MD, Sarit Assouline, John Radford, MD FRCP, John G. Gribben, Corinne Haioun, MD, Aristeidis Chaidos, MD PhD, Steven Le Gouill, MD PhD, Alicia Clawson, John Larus, Stephen J Blakemore
Journal: Blood
Blood (2018) 132 (Supplement 1): 4097.
https://doi.org/10.1182/blood-2018-99-115132
Published: 2018
Journal Articles

Discovery of Candidate Predictors of Response to Tazemetostat in Diffuse Large B-Cell Lymphoma and Follicular Lymphoma Using NGS Technology on ctDNA Samples Collected Pre-Treatment

Free
Scott Daigle, Alice A. McDonald, BA, Franck Morschhauser, MD PhD, Gilles Salles, MD, Vincent Ribrag, Pamela McKay, Herve Tilly, Anna Schmitt, John Gerecitano, MD PhD, Christophe Fruchart, MD, Peter Johnson, MD FRCP, John Radford, MD, Michael J. Dickinson, Charles Herbaux, Stephen Opat, FRACP, FRCPA, Wojciech Jurczak, PhDMD, Guillaume Cartron, Thierry Lamy, Pr, MD PhD, Pier Luigi Zinzani, MD, Sarit Assouline, MD, Ryan D. Morin, PhDBSc,MSc, Helen Wu, Mark Sausen, Alicia Clawson, Peter Ho, Harry Miao, Stephen Blakemore
Journal: Blood
Blood (2017) 130 (Supplement 1): 4013.
https://doi.org/10.1182/blood.V130.Suppl_1.4013.4013
Published: 2017
Journal Articles

Pharmacodynamic Study of Copanlisib in Patients with Non-Hodgkin's Lymphoma and Advanced Solid Tumors: Confirmation of on-Target PI3K Inhibitory Activity

Free
Franck Morschhauser, MD PhD, Ahmad Awada, MD PhD, Jean-Pascal Machiels, MD PhD, Gilles Andre Salles, MD PhD, Sylvie Rottey, MD PhD, Simon Rule, MD, David Cunningham, MD FRCP, Frederic Peyrade, MD, Christophe Fruchart, MD, Hendrik-Tobias Arkenau, MD PhD, Isabelle Genvresse, MD, Li Liu, PhD, Christoph Kneip, PhD, Carol Pena, PhD, Joachim Grevel, PhD, Jun Zhang, PhD, Galia Cisternas, PhD, Susanne Reschke, MSc, Camille Granvil, PhD
Journal: Blood
Blood (2017) 130 (Supplement 1): 1256.
https://doi.org/10.1182/blood.V130.Suppl_1.1256.1256
Published: 2017
Journal Articles

First Analysis of an International Double-Blind Randomized Phase III Study of Lenalidomide Maintenance in Elderly Patients with DLBCL Treated with R-CHOP in First Line, the Remarc Study from Lysa

Free
Catherine Thieblemont, MD PhD, Hervé Tilly, MD PhD, Maria Gomez da Silva, Rene-Olivier Casasnovas, MD, Christophe Fruchart, MD, Franck Morschhauser, Corinne Haioun, MD PhD, Julien Lazarovici, MD, Sebastian Grosicki, Aurore Perrot, MD, Judith Trotman, MBChB, Catherine Sebban, MD, Dolores Caballero, Richard Greil, MD, Koen Van Eygen, Josette Briere, Jose Cabecadas, Gilles Andre Salles, Philippe Gaulard, MD PhD, Andre Bosly, MD PhD, Bertrand Coiffier
Journal: Blood
Blood (2016) 128 (22): 471.
https://doi.org/10.1182/blood.V128.22.471.471
Published: 2016
Journal Articles

Incidence and Risk Factors for Central Nervous System Relapse in Very Elderly Patients over 80 with Diffuse Large B-Cell Lymphoma: A Retrospective Analysis of Two Lysa Studies

Free
Aurelie Cabannes-Hamy, MD, Frederic Peyrade, MD, Fabrice Jardin, MD PhD, Jean-Francois Emile, Sylvie Castaigne, MD PhD, Bertrand Coiffier, MD PhD, Corinne Haioun, MD, Aurore Perrot, MD, Olivier Fitoussi, MD, Safia Chebrek, Christophe Fruchart, Julie Abraham, MD, Richard Delarue, MD, Marc Andre, MD, Gilles Salles, MD PhD, Philippe Gaulard, MD PhD, Herve Tilly, MD PhD, Catherine Thieblemont, MD PhD
Journal: Blood
Blood (2016) 128 (22): 927.
https://doi.org/10.1182/blood.V128.22.927.927
Published: 2016
Journal Articles

Ibrutinib in Association with R-DHAP/Ox for Patients with Relapsed/Refractory B-Cell Lymphoma: Preliminary Results of the Biblos Phase Ib Lysa Study

Free
Christophe Bonnet, MD PhD, Thierry Lamy, MD PhD, Christophe Fruchart, MD, Steven Le Gouill, MD PhD, Katharina Gunzer, MD, Thomas Gastinne, MD, Fabrice Jardin, MD PhD, Lionel Karlin, MD, Roch Houot, MD PhD, Jehan Dupuis, MD, Hervé Tilly, MD PhD, Gilles A. Salles
Journal: Blood
Blood (2016) 128 (22): 5384.
https://doi.org/10.1182/blood.V128.22.5384.5384
Published: 2016
Journal Articles

A Phase II LYSA Study of Obinutuzumab Combined with Lenalidomide for Relapsed or Refractory Aggressive B-Cell Lymphoma

Free
Franck Morschhauser, MD PhD, Guillaume Cartron, MD PhD, Gilles A. Salles, Fontanet Bijou, MD, Christophe Fruchart, MD, Krimo Bouabdallah, MD, Pierre Feugier, MD PhD, Steven Le Gouill, MD PhD, Hervé Tilly, MD PhD, Cecile moluçon-Chabrot, MD, Marie Maerevoet, MD, Rene-Olivier Casasnovas, MD, Eric W Van Den Neste, MD PhD, Pierre Zachee, Koen Van Eygen, MD, Achiel Van Hoof, MD, Christophe Bonnet, MD PhD, Corinne Haioun, MD, Marc Andre, MD, Luc Xerri, MD PhD, Roch Houot, MD PhD
Journal: Blood
Blood (2016) 128 (22): 4202.
https://doi.org/10.1182/blood.V128.22.4202.4202
Published: 2016
Journal Articles

Yttrium-90 Ibritumomab Tiuxetan Is Feasible and Efficient in Unselected Patients. Definitive Results of a Large Retrospective Phase IV Study

Free
Valentine Richez, Jr., MD, Julie Abraham, MD, Sandy Amorim, MD, Charles Herbaux, MD, Laure Philippe, MDcal student, Marc Andre, MD, Anne Parcelier, MD, Christophe Fruchart, MD, Krimo Bouabdallah, MD, Jérôme Cornillon, MD, Sigrid Cherrier, MD, Clementine Salvado, MD, Bernard Drenou, MD, Lucie Oberic, MD, Philippe Quittet, MD, Geoffroy Venton, MD, Claire Calmettes, MD, Safia Chebrek, MD, Cedric Rossi, MD, Arnaud Campidelli, MD, Bruno Lioure, MD, Sophie Auger, MD, Lucille Altounian, MD, Philippe Mineur, MD, Erwin Woff, MD, Frederic Peyrade, MD
Journal: Blood
Blood (2015) 126 (23): 5108.
https://doi.org/10.1182/blood.V126.23.5108.5108
Published: 2015