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Journal Articles

JAK inhibition for murine HLH requires complete blockade of IFN-γ signaling and is limited by toxicity of JAK2 inhibition

Vandana Chaturvedi, Nora Lakes, Minh Tran, Natalie Castillo, Michael B. Jordan

Blood (2021) 138 (12): 1034–1039.

https://doi.org/10.1182/blood.2020007930

Published: 2021

Journal Articles

Cytokine combinations for human blood stem cell expansion induce cell-type– and cytokine-specific signaling dynamics

Weijia Wang, Yang Zhang, Philip Dettinger, Andreas Reimann, Tobias Kull, Dirk Loeffler, Markus G. Manz, Claudia Lengerke, Timm Schroeder

Blood (2021) 138 (10): 847–857.

https://doi.org/10.1182/blood.2020008386

Published: 2021

Includes: Multimedia, Supplemental data

Journal Articles

Targeting the plasticity of mesenchymal stromal cells to reroute the course of acute myeloid leukemia

Blood (2021) 138 (7): 557–570.

https://doi.org/10.1182/blood.2020009845

Published: 2021

Includes: Multimedia, Supplemental data

Journal Articles

FXII inhibition: multipronged benefits

Helen Philippou

Blood (2021) 138 (2): 107–109.

https://doi.org/10.1182/blood.2021011032

Published: 2021

Journal Articles

Osteocytes regulate neutrophil development through IL-19: a potent cytokine for neutropenia treatment

Min Xiao, Wuju Zhang, Wen Liu, Linlin Mao, Jincheng Yang, Le Hu, Sheng Zhang, Yaling Zheng, Anling Liu, Qiancheng Song, Yuhua Li, Guozhi Xiao, Zhipeng Zou, Xiaochun Bai

Blood (2021) 137 (25): 3533–3547.

https://doi.org/10.1182/blood.2020007731

Published: 2021

Includes: Supplemental data

Journal Articles

A JAK/STAT-mediated inflammatory signaling cascade drives oncogenesis in AF10-rearranged AML

Blood (2021) 137 (24): 3403–3415.

https://doi.org/10.1182/blood.2020009023

Published: 2021

Includes: Supplemental data

Journal Articles

Cytokine-like protein 1–induced survival of monocytes suggests a combined strategy targeting MCL1 and MAPK in CMML

Blood (2021) 137 (24): 3390–3402.

https://doi.org/10.1182/blood.2020008729

Published: 2021

Includes: Supplemental data

Journal Articles

Molecular and cellular features of CTLA-4 blockade for relapsed myeloid malignancies after transplantation

Blood (2021) 137 (23): 3212–3217.

https://doi.org/10.1182/blood.2021010867

Published: 2021

Includes: Supplemental data

Journal Articles

TLR8 gain of function: a tall surprise

Bertrand Boisson, Jean-Laurent Casanova

Blood (2021) 137 (18): 2420–2422.

https://doi.org/10.1182/blood.2020010463

Published: 2021

Journal Articles

Immunodeficiency and bone marrow failure with mosaic and germline TLR8 gain of function

Blood (2021) 137 (18): 2450–2462.

https://doi.org/10.1182/blood.2020009620

Published: 2021

Includes: Supplemental data

Journal Articles

An ounce of which prevention is worth a…?

Joerg Halter, Jakob Passweg

Blood (2021) 137 (14): 1852–1853.

https://doi.org/10.1182/blood.2021010688

Published: 2021

Journal Articles

Overcoming T-cell exhaustion in LCH: PD-1 blockade and targeted MAPK inhibition are synergistic in a mouse model of LCH

Amel Sengal, Jessica Velazquez, Meryl Hahne, Thomas M. Burke, Harshal Abhyankar, Robert Reyes, Walter Olea, Brooks Scull, Olive S. Eckstein, Camille Bigenwald, Catherine M. Bollard, Wendong Yu, Miriam Merad, Kenneth L. McClain, Carl E. Allen, Rikhia Chakraborty

Blood (2021) 137 (13): 1777–1791.

https://doi.org/10.1182/blood.2020005867

Published: 2021

Includes: Supplemental data

Journal Articles

Rapid single-molecule digital detection of protein biomarkers for continuous monitoring of systemic immune disorders

Blood (2021) 137 (12): 1591–1602.

https://doi.org/10.1182/blood.2019004399

Published: 2021

Includes: Supplemental data

Journal Articles

Resolving thromboinflammation

Stephen P. McAdoo, Neeraj Dhaun

Blood (2021) 137 (11): 1444–1446.

https://doi.org/10.1182/blood.2020010627

Published: 2021

Journal Articles

Targeting a cytokine checkpoint enhances the fitness of armored cord blood CAR-NK cells

May Daher, Rafet Basar, Elif Gokdemir, Natalia Baran, Nadima Uprety, Ana Karen Nunez Cortes, Mayela Mendt, Lucila Nassif Kerbauy, Pinaki P. Banerjee, Mayra Shanley, Nobuhiko Imahashi, Li Li, Francesca Lorraine Wei Inng Lim, Mohsen Fathi, Ali Rezvan, Vakul Mohanty, Yifei Shen, Hila Shaim, Junjun Lu, Gonca Ozcan, Emily Ensley, Mecit Kaplan, Vandana Nandivada, Mustafa Bdiwi, Sunil Acharya, Yuanxin Xi, Xinhai Wan, Duncan Mak, Enli Liu, Xin Ru Jiang, Sonny Ang, Luis Muniz-Feliciano, Ye Li, Jing Wang, Shahram Kordasti, Nedyalko Petrov, Navin Varadarajan, David Marin, Lorenzo Brunetti, Richard J. Skinner, Shangrong Lyu, Leiser Silva, Rolf Turk, Mollie S. Schubert, Garrett R. Rettig, Matthew S. McNeill, Gavin Kurgan, Mark A. Behlke, Heng Li, Natalie W. Fowlkes, Ken Chen, Marina Konopleva, Richard E. Champlin, Elizabeth J. Shpall, Katayoun Rezvani

Blood (2021) 137 (5): 624–636.

https://doi.org/10.1182/blood.2020007748

Published: 2021

Includes: Supplemental data

Journal Articles

I have a gut feeling…

Nelson J. Chao

Blood (2020) 136 (12): 1380.

https://doi.org/10.1182/blood.2020007186

Published: 2020

Journal Articles

JAK/STAT pathway inhibition sensitizes CD8 T cells to dexamethasone-induced apoptosis in hyperinflammation

Lauren K. Meyer, Katherine C. Verbist, Sabrin Albeituni, Brooks P. Scull, Rachel C. Bassett, Alexa N. Stroh, Heather Tillman, Carl E. Allen, Michelle L. Hermiston, Kim E. Nichols

Blood (2020) 136 (6): 657–668.

https://doi.org/10.1182/blood.2020006075

Published: 2020

Includes: Supplemental data

Journal Articles

Cytokines and costimulation in acute graft-versus-host disease

Geoffrey R. Hill, Motoko Koyama

Blood (2020) 136 (4): 418–428.

https://doi.org/10.1182/blood.2019000952

Published: 2020

Journal Articles

Aging-induced IL27Ra signaling impairs hematopoietic stem cells

Hanqing He, Panglian Xu, Xiaofei Zhang, Min Liao, Qiongye Dong, Tingting Cong, Baixue Tang, Xiuxiu Yang, Maoqing Ye, Yingjun Chang, Weihua Liu, Xiaowo Wang, Zhenyu Ju, Jianwei Wang

Blood (2020) 136 (2): 183–198.

https://doi.org/10.1182/blood.2019003910

Published: 2020

Includes: Supplemental data

Journal Articles

Poly(I:C) causes failure of immunoprophylaxis to red blood cells expressing the KEL glycoprotein in mice

Vicente Escamilla-Rivera, Jingchun Liu, David R. Gibb, Manjula Santhanakrishnan, Dong Liu, James E. Forsmo, Stephanie C. Eisenbarth, Ellen F. Foxman, Sean R. Stowell, Chance John Luckey, James C. Zimring, Krystalyn E. Hudson, Jeanne E. Hendrickson

Blood (2020) 135 (22): 1983–1993.

https://doi.org/10.1182/blood.2020005018

Published: 2020

Includes: Supplemental data

NARROW

JAK inhibition for murine HLH requires complete blockade of IFN-γ signaling and is limited by toxicity of JAK2 inhibition

Cytokine combinations for human blood stem cell expansion induce cell-type– and cytokine-specific signaling dynamics

Targeting the plasticity of mesenchymal stromal cells to reroute the course of acute myeloid leukemia

FXII inhibition: multipronged benefits

Osteocytes regulate neutrophil development through IL-19: a potent cytokine for neutropenia treatment

A JAK/STAT-mediated inflammatory signaling cascade drives oncogenesis in AF10-rearranged AML

Cytokine-like protein 1–induced survival of monocytes suggests a combined strategy targeting MCL1 and MAPK in CMML

Molecular and cellular features of CTLA-4 blockade for relapsed myeloid malignancies after transplantation

TLR8 gain of function: a tall surprise

Immunodeficiency and bone marrow failure with mosaic and germline TLR8 gain of function

An ounce of which prevention is worth a…?

Overcoming T-cell exhaustion in LCH: PD-1 blockade and targeted MAPK inhibition are synergistic in a mouse model of LCH

Rapid single-molecule digital detection of protein biomarkers for continuous monitoring of systemic immune disorders

Resolving thromboinflammation

Targeting a cytokine checkpoint enhances the fitness of armored cord blood CAR-NK cells

I have a gut feeling…

JAK/STAT pathway inhibition sensitizes CD8 T cells to dexamethasone-induced apoptosis in hyperinflammation

Cytokines and costimulation in acute graft-versus-host disease

Aging-induced IL27Ra signaling impairs hematopoietic stem cells

Poly(I:C) causes failure of immunoprophylaxis to red blood cells expressing the KEL glycoprotein in mice

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American Society of Hematology

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American Society of Hematology

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