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Management of chronic viral hepatitis in patients with thalassemia: recommendations from an international panel
Nomenclature of monocytes and dendritic cells in blood
Impact of in vivo alemtuzumab dose before reduced intensity conditioning and HLA-identical sibling stem cell transplantation: pharmacokinetics, GVHD, and immune reconstitution
Issue Archive
October 21 2010
In this Issue
Table of Contents
Inside blood
Perspectives
Management of chronic viral hepatitis in patients with thalassemia: recommendations from an international panel
Clinical Trials & Observations
Vito Di Marco,Marcello Capra,Emanuele Angelucci,Caterina Borgna-Pignatti,Paul Telfer,Paul Harmatz,Antonis Kattamis,Luciano Prossamariti,Aldo Filosa,Deborah Rund,Maria Rita Gamberini,Paolo Cianciulli,Marianne De Montalembert,Francesco Gagliardotto,Graham Foster,Jean Didier Grangè,Filippo Cassarà,Angela Iacono,Maria Domenica Cappellini,Gary M. Brittenham,Daniele Prati,Antonello Pietrangelo,Antonio Craxì,Aurelio Maggio,on behalf of the Italian Society for the Study of Thalassemia and Haemoglobinopathies and Italian Association for the Study of the Liver
Review Article
Clinical Trials and Observations
Hematopoiesis and Stem Cells
Genetic disruption of both Fancc and Fancg in mice recapitulates the hematopoietic manifestations of Fanconi anemia
Anna C. Pulliam-Leath,Samantha L. Ciccone,Grzegorz Nalepa,Xiaxin Li,Yue Si,Leticia Miravalle,Danielle Smith,Jin Yuan,Jingling Li,Praveen Anur,Attilio Orazi,Gail H. Vance,Feng-Chun Yang,Helmut Hanenberg,Grover C. Bagby,D. Wade Clapp
Immunobiology
Vimentin/cardiolipin complex as a new antigenic target of the antiphospholipid syndrome
Elena Ortona,Antonella Capozzi,Tania Colasanti,Fabrizio Conti,Cristiano Alessandri,Agostina Longo,Tina Garofalo,Paola Margutti,Roberta Misasi,Munther A. Khamashta,Graham R. V. Hughes,Guido Valesini,Maurizio Sorice
Fc-engineered anti-CD40 antibody enhances multiple effector functions and exhibits potent in vitro and in vivo antitumor activity against hematologic malignancies
Holly M. Horton,Matthew J. Bernett,Matthias Peipp,Erik Pong,Sher Karki,Seung Y. Chu,John O. Richards,Hsing Chen,Roland Repp,John R. Desjarlais,Eugene A. Zhukovsky
Lymphoid Neoplasia
LEF-1 is a prosurvival factor in chronic lymphocytic leukemia and is expressed in the preleukemic state of monoclonal B-cell lymphocytosis
Albert Gutierrez, Jr,Renee C. Tschumper,Xiaosheng Wu,Tait D. Shanafelt,Jeanette Eckel-Passow,Paul M. Huddleston, III,Susan L. Slager,Neil E. Kay,Diane F. Jelinek
Epigenetic silencing of BIM in glucocorticoid poor-responsive pediatric acute lymphoblastic leukemia, and its reversal by histone deacetylase inhibition
Petra S. Bachmann,Rocco G. Piazza,Mary E. Janes,Nicholas C. Wong,Carwyn Davies,Angela Mogavero,Vivek A. Bhadri,Barbara Szymanska,Greta Geninson,Vera Magistroni,Giovanni Cazzaniga,Andrea Biondi,Diego Miranda-Saavedra,Berthold Göttgens,Richard Saffery,Jeffrey M. Craig,Glenn M. Marshall,Carlo Gambacorti-Passerini,John E. Pimanda,Richard B. Lock
AICAR induces apoptosis independently of AMPK and p53 through up-regulation of the BH3-only proteins BIM and NOXA in chronic lymphocytic leukemia cells
Antonio F. Santidrián,Diana M. González-Gironès,Daniel Iglesias-Serret,Llorenç Coll-Mulet,Ana M. Cosialls,Mercè de Frias,Clara Campàs,Eva González-Barca,Esther Alonso,Verena Labi,Benoit Viollet,Adalberto Benito,Gabriel Pons,Andreas Villunger,Joan Gil
Phagocytes, Granulocytes, and Myelopoiesis
Nomenclature of monocytes and dendritic cells in blood
e-blood
Loems Ziegler-Heitbrock,Petronela Ancuta,Suzanne Crowe,Marc Dalod,Veronika Grau,Derek N. Hart,Pieter J. M. Leenen,Yong-Jun Liu,Gordon MacPherson,Gwendalyn J. Randolph,Juergen Scherberich,Juergen Schmitz,Ken Shortman,Silvano Sozzani,Herbert Strobl,Marek Zembala,Jonathan M. Austyn,Manfred B. Lutz
Platelets and Thrombopoiesis
Red Cells, Iron, and Erythropoiesis
Thrombosis and Hemostasis
Transfusion Medicine
Transplantation
Impact of in vivo alemtuzumab dose before reduced intensity conditioning and HLA-identical sibling stem cell transplantation: pharmacokinetics, GVHD, and immune reconstitution
Clinical Trials & Observations
Ronjon Chakraverty,Guillermo Orti,Michael Roughton,Jun Shen,Adele Fielding,Panagiotis Kottaridis,Donald Milligan,Matthew Collin,Charles Crawley,Peter Johnson,Andrew Clark,Anne Parker,Adrian Bloor,Ruth Pettengell,John Snowden,Andrew Pettitt,Richard Clark,Geoff Hale,Karl Peggs,Kirsty Thomson,Emma Morris,Stephen Mackinnon
Vascular Biology
Platelet-derived growth factor (PDGF)–PDGF receptor interaction activates bone marrow–derived mesenchymal stromal cells derived from chronic lymphocytic leukemia: implications for an angiogenic switch
Wei Ding,Traci R. Knox,Renee C. Tschumper,Wenting Wu,Susan M. Schwager,Justin C. Boysen,Diane F. Jelinek,Neil E. Kay
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Cover Image
Cover Image
![issue cover]()
Increased angiogenic signaling results in centrosome overduplication and formation of aberrant mitotic spindles in endothelial cells. The cover image shows a mitotic human umbilical vein endothelial cell treated with high concentrations of VEGF containing 4 centrosomes (yellow) that nucleate microtubules (red) to form 4 distinct mitotic spindles, which, in turn, organize the chromosomes (blue); the multipolar spindle is abnormal and is predicted to lead to aneuploidy. See the article by Taylor et al on page 3108.
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