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Journal Articles

Regulatory T Cell Selective IL-2-Fc Fusion Proteins for the Treatment of Autoimmune Diseases

Rajat Varma, PhD, Ke Liu, PhD, Kendra Avery, PhD, Rumana Rashid, PhD, Suzanne Schubbert, PhD, Irene Leung, PhD, Christine Bonzon, PhD, Liz Bogaert, PhD, John Desjarlais, Matthew J. Bernett

Blood (2018) 132 (Supplement 1): 3709.

https://doi.org/10.1182/blood-2018-99-117622

Published: 2018

Journal Articles

Preclinical Characterization of AMG 424, a Novel Humanized T Cell-Recruiting Bispecific Anti-CD3/CD38 Antibody

Blood (2017) 130 (Supplement 1): 500.

https://doi.org/10.1182/blood.V130.Suppl_1.500.500

Published: 2017

Journal Articles

Tuning T Cell Affinity Improves Efficacy and Safety of Anti-CD38 × Anti-CD3 Bispecific Antibodies in Monkeys - a Potential Therapy for Multiple Myeloma

Gregory L. Moore, PhD, Sung-Hyung Lee, PhD, Suzanne Schubbert, PhD, Yvonne Miranda, MS, Rumana Rashid, PhD, Erik Pong, BS, Sheryl Phung, MS, Emily W. Chan, BS, Hsing Chen, MS, Nancy Endo, BS, Maria C. Ardila, BS, Matthew J. Bernett, PhD, Seung Chu, PhD, Irene W.L. Leung, PhD, Umesh Muchhal, PhD, Christine Bonzon, PhD, David E Szymkowski, PhD, John Desjarlais, PhD

Blood (2015) 126 (23): 1798.

https://doi.org/10.1182/blood.V126.23.1798.1798

Published: 2015

Journal Articles

Immunotherapy with Long-Lived Anti-CD123 × Anti-CD3 Bispecific Antibodies Stimulates Potent T Cell-Mediated Killing of Human AML Cell Lines and of CD123+ Cells in Monkeys: A Potential Therapy for Acute Myelogenous Leukemia

Seung Y. Chu, PhD, Erik Pong, MS, Hsing Chen, MS, Sheryl Phung, MS, Emily W. Chan, BS, Nancy A. Endo, BS, Rumana Rashid, PhD, Christine Bonzon, PhD, Irene W.L. Leung, PhD, Umesh S. Muchhal, PhD, Gregory L. Moore, PhD, Matthew J. Bernett, PhD, David E. Szymkowski, PhD, John R. Desjarlais, PhD

Blood (2014) 124 (21): 2316.

https://doi.org/10.1182/blood.V124.21.2316.2316

Published: 2014

Journal Articles

Immunotherapy with Long-Lived Anti-CD20 × Anti-CD3 Bispecific Antibodies Stimulates Potent T Cell-Mediated Killing of Human B Cell Lines and of Circulating and Lymphoid B Cells in Monkeys: A Potential Therapy for B Cell Lymphomas and Leukemias

Seung Y. Chu, PhD, Sung-Hyung Lee, PhD, Rumana Rashid, PhD, Hsing Chen, MS, Emily W. Chan, BS, Sheryl Phung, MS, Erik Pong, MS, Nancy A. Endo, BS, Yvonne Miranda, MS, Christine Bonzon, PhD, Irene W.L. Leung, PhD, Umesh S. Muchhal, PhD, Gregory L. Moore, PhD, Matthew J. Bernett, PhD, David E. Szymkowski, PhD, John R. Desjarlais, PhD

Blood (2014) 124 (21): 3111.

https://doi.org/10.1182/blood.V124.21.3111.3111

Published: 2014

Journal Articles

Immunotherapy with Long-Lived Anti-CD38 × Anti-CD3 Bispecific Antibodies Stimulates Potent T Cell-Mediated Killing of Human Myeloma Cell Lines and CD38+ Cells in Monkeys: A Potential Therapy for Multiple Myeloma

Seung Y. Chu, PhD, Yvonne Miranda, MS, Sheryl Phung, MS, Hsing Chen, MS, Rumana Rashid, PhD, Nancy A. Endo, BS, Emily W. Chan, BS, Erik Pong, MS, Christine Bonzon, PhD, Umesh S. Muchhal, PhD, Irene W.L. Leung, PhD, Matthew J. Bernett, PhD, Gregory L. Moore, PhD, David E. Szymkowski, PhD, John R. Desjarlais, PhD

Blood (2014) 124 (21): 4727.

https://doi.org/10.1182/blood.V124.21.4727.4727

Published: 2014

Journal Articles

Potent in vitro and in vivo activity of an Fc-engineered humanized anti-HM1.24 antibody against multiple myeloma via augmented effector function

Yu-Tzu Tai, Holly M. Horton, Sun-Young Kong, Erik Pong, Hsing Chen, Saso Cemerski, Matthew J. Bernett, Duc-Hanh T. Nguyen, Sher Karki, Seung Y. Chu, Greg A. Lazar, Nikhil C. Munshi, John R. Desjarlais, Kenneth C. Anderson, Umesh S. Muchhal

Blood (2012) 119 (9): 2074–2082.

https://doi.org/10.1182/blood-2011-06-364521

Published: 2012

Includes: Supplemental data

Journal Articles

Fc-engineered anti-CD40 antibody enhances multiple effector functions and exhibits potent in vitro and in vivo antitumor activity against hematologic malignancies

Holly M. Horton, Matthew J. Bernett, Matthias Peipp, Erik Pong, Sher Karki, Seung Y. Chu, John O. Richards, Hsing Chen, Roland Repp, John R. Desjarlais, Eugene A. Zhukovsky

Blood (2010) 116 (16): 3004–3012.

https://doi.org/10.1182/blood-2010-01-265280

Published: 2010

NARROW

Regulatory T Cell Selective IL-2-Fc Fusion Proteins for the Treatment of Autoimmune Diseases

Preclinical Characterization of AMG 424, a Novel Humanized T Cell-Recruiting Bispecific Anti-CD3/CD38 Antibody

Tuning T Cell Affinity Improves Efficacy and Safety of Anti-CD38 × Anti-CD3 Bispecific Antibodies in Monkeys - a Potential Therapy for Multiple Myeloma

Immunotherapy with Long-Lived Anti-CD123 × Anti-CD3 Bispecific Antibodies Stimulates Potent T Cell-Mediated Killing of Human AML Cell Lines and of CD123+ Cells in Monkeys: A Potential Therapy for Acute Myelogenous Leukemia

Immunotherapy with Long-Lived Anti-CD20 × Anti-CD3 Bispecific Antibodies Stimulates Potent T Cell-Mediated Killing of Human B Cell Lines and of Circulating and Lymphoid B Cells in Monkeys: A Potential Therapy for B Cell Lymphomas and Leukemias

Immunotherapy with Long-Lived Anti-CD38 × Anti-CD3 Bispecific Antibodies Stimulates Potent T Cell-Mediated Killing of Human Myeloma Cell Lines and CD38+ Cells in Monkeys: A Potential Therapy for Multiple Myeloma

Potent in vitro and in vivo activity of an Fc-engineered humanized anti-HM1.24 antibody against multiple myeloma via augmented effector function

Fc-engineered anti-CD40 antibody enhances multiple effector functions and exhibits potent in vitro and in vivo antitumor activity against hematologic malignancies

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American Society of Hematology

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ASH Publications

American Society of Hematology

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