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Journal Articles

A JAK/STAT-mediated inflammatory signaling cascade drives oncogenesis in AF10-rearranged AML

Blood (2021) 137 (24): 3403–3415.

https://doi.org/10.1182/blood.2020009023

Published: 2021

Includes: Supplemental data

Journal Articles

JAK/STAT pathway inhibition sensitizes CD8 T cells to dexamethasone-induced apoptosis in hyperinflammation

Lauren K. Meyer, Katherine C. Verbist, Sabrin Albeituni, Brooks P. Scull, Rachel C. Bassett, Alexa N. Stroh, Heather Tillman, Carl E. Allen, Michelle L. Hermiston, Kim E. Nichols

Blood (2020) 136 (6): 657–668.

https://doi.org/10.1182/blood.2020006075

Published: 2020

Includes: Supplemental data

Journal Articles

Gene alterations in epigenetic modifiers and JAK-STAT signaling are frequent in breast implant–associated ALCL

Blood (2020) 135 (5): 360–370.

https://doi.org/10.1182/blood.2019001904

Published: 2020

Includes: Supplemental data

Journal Articles

HDAC11 deficiency disrupts oncogene-induced hematopoiesis in myeloproliferative neoplasms

Blood (2020) 135 (3): 191–207.

https://doi.org/10.1182/blood.2019895326

Published: 2020

Includes: Supplemental data

Journal Articles

Genomic analyses of PMBL reveal new drivers and mechanisms of sensitivity to PD-1 blockade

Bjoern Chapuy, Chip Stewart, Andrew J. Dunford, Jaegil Kim, Kirsty Wienand, Atanas Kamburov, Gabriel K. Griffin, Pei-Hsuan Chen, Ana Lako, Robert A. Redd, Claire M. Cote, Matthew D. Ducar, Aaron R. Thorner, Scott J. Rodig, Gad Getz, Margaret A. Shipp

Blood (2019) 134 (26): 2369–2382.

https://doi.org/10.1182/blood.2019002067

Published: 2019

Includes: Supplemental data

Journal Articles

Global Gene Expression and Mutation Signatures Are Preserved in PDX Models of Pediatric AML and Aid Discovery of Targeted Therapy for Cases with CBFA2T3/GLIS2 Rearrangement

Mark Wunderlich, MS, Jing Chen, Eric O'Brien, BSc, Nicole Manning, Christina Sexton, Luke Byerly, John P Perentesis, Benjamin Mizukawa, James C Mulloy

Blood (2019) 134 (Supplement_1): 3766.

https://doi.org/10.1182/blood-2019-129225

Published: 2019

Journal Articles

The Clinical and Functional Relevance of the Transforming AKT E17K Mutation in T-ALL

Jordy C.G. Van Der Zwet, MD, Jessica G.C.A.M. Buijs-Gladdines, Izabela Mollova, BSc, Laura Graus, BSc, Frank L. Bos, PhD, Anne C. Rios, PhD, Jules P.P. Meijerink, PhD

Blood (2019) 134 (Supplement_1): 3804.

https://doi.org/10.1182/blood-2019-124669

Published: 2019

Journal Articles

Small Molecule-Induced, Selective STAT3 Degradation Leads to Anti-Tumor Activity in STAT3-Dependent Heme Malignancies

Fred Csibi, Nan Ji, PhD, Bin Yang, Karen Yuan, Michele Mayo, Haojing Rong, PhD, Scott Rusin, Kirti Sharma, Christine Loh, PhD, Henry Li, PhD, Sharon Townson, Jesse Chen, PhD, Hari Kamadurai, PhD, Duncan Walker, PhD, Jared Gollob, PhD MD, Nello Mainolfi, PhD

Blood (2019) 134 (Supplement_1): 3803.

https://doi.org/10.1182/blood-2019-128981

Published: 2019

Journal Articles

Stat3 Is Activated By ROS to Uniquely Regulate Primitive Erythropoiesis

Zachary C. Murphy, PhD, Kathleen E. McGrath, PhD, James Palis, MD

Blood (2019) 134 (Supplement_1): 2216.

https://doi.org/10.1182/blood-2019-127229

Published: 2019

Journal Articles

Cross-Talk between Cytokine and NF-ĸb Signaling in the CLL Microenvironment Can Affect Sensitivity for Venetoclax

Marco Haselager, MSc, Rachel Thijssen, Arnon P. Kater, Eric Eldering

Blood (2019) 134 (Supplement_1): 5449.

https://doi.org/10.1182/blood-2019-126788

Published: 2019

Journal Articles

The Validation of the BCR/ABL1 -like Predictor across Laboratories Shows Reproducibility of Results

Sabina Chiaretti, MD PhD, Taherinasab Akram, Canichella Martina, Monica Messina, Alfonso Piciocchi, Cyril Šálek, MD PhD, Katerina Machova, Katerina Blagoevova, Jordi Ribera, PhD, Josep-Maria Ribera, MD PhD, Manja Meggendorfer, PhD, Claudia Haferlach, MD, Anna Guarini, PhD, Robin Foà, MD

Blood (2019) 134 (Supplement_1): 5211.

https://doi.org/10.1182/blood-2019-122116

Published: 2019

Journal Articles

Mutations in Triple-Negative Patients with Myeloproliferative Neoplasms

Maria Carolina Costa Melo Svidnicki, PhD, Paula De Melo Campos, MD, Moisés Alves Ferreira Filho, PhD, Caio Augusto Leme Fujiura, Tetsuichi Yoshizato, MD PhD, Hideki Makishima, MD PhD, Seishi Ogawa, MD PhD, Sara T Olalla Saad, PhD

Blood (2019) 134 (Supplement_1): 5395.

https://doi.org/10.1182/blood-2019-128764

Published: 2019

Journal Articles

Ruxolitinib, a JAK1/JAK2 Selective Inhibitor, Ameliorates Gastrointestinal and Cutaneous Pathogenesis in MHC-Mismatched Preclinical Models of Acute and Chronic Graft-Versus-Host Disease

Eduardo Huarte, PhD, Melissa Parker, Ashish Juvekar, Julian Oliver, Wenqing Yao, Paul Smith

Blood (2019) 134 (Supplement_1): 5608.

https://doi.org/10.1182/blood-2019-126749

Published: 2019

Journal Articles

Dual Driver Mutant BCR-ABL1-Negative Myeloid Neoplasms: Multicenter Clinicopathologic and Genomic Analysis

Zachary D. Epstein-Peterson, MD, Joseph Tripodi, Maria E Arcila, MD, Filiz Sen, MD, Vesna Najfeld, PhD, John Mascarenhas, MD, Ronald Hoffman, MD, Rajit K. Rampal, MD, PhD

Blood (2019) 134 (Supplement_1): 4173.

https://doi.org/10.1182/blood-2019-125379

Published: 2019

Journal Articles

Characterization of a Novel JAK1 Pseudokinase Mutation in the First Case of Trisomy 21-Independent GATA1-Mutated Transient Abnormal Myelopoiesis

Julius Lukes, Jr., MD, Petr Danek, MSc, Oriol Alejo, Eliska Potuckova, Ondrej Gahura, Dirk Heckl, PhD, Julia Starkova, PhD, Jan Zuna, Jan Stary, Prof., MD PhD, Jan Trka, Prof., MD PhD, Jan-Henning Klusmann, Marketa Zaliova, MD PhD

Blood (2019) 134 (Supplement_1): 4208.

https://doi.org/10.1182/blood-2019-122168

Published: 2019

Journal Articles

Altered Dynamics of Monocyte Subpopulations and Pro-Inflammatory Signaling Pathways in Polycythemia Vera Revealed By Mass Cytometry

Jared S Fowles, PhD, Daniel A.C. Fisher, PhD, Amy Zhou, MD, Stephen T. Oh, MD

Blood (2019) 134 (Supplement_1): 4210.

https://doi.org/10.1182/blood-2019-131128

Published: 2019

Journal Articles

Hypoxia Inducible Factors' Transcriptional Activity in Polycythemia Vera

Jihyun Song, PhD, Soo Jin Kim, MS, Victor R Gordeuk, MD, Josef T. Prchal, MD

Blood (2019) 134 (Supplement_1): 4211.

https://doi.org/10.1182/blood-2019-131909

Published: 2019

Journal Articles

RMC-4550, an Allosteric Inhibitor of SHP2, Displays Therapeutic Efficacy in Pre-Clinical Models of Myeloproliferative Neoplasms

Garima Pandey, Nathan Horvat, Narmin E. Amin, Afua A. Akuffo, Christelle Colin, Pearlie K. Epling-Burnette, Gary W. Reuther

Blood (2019) 134 (Supplement_1): 4198.

https://doi.org/10.1182/blood-2019-128937

Published: 2019

Journal Articles

Activation of AKT/mTOR Pathway in Ph+ Acute Lymphoblastic Leukemia (ALL) Leads to Non-Mutational Resistance

Afsar Ali Mian, BSc, MPhil, PhD, Usva Zafar, BSc, Oliver Ottmann, Prof, MD, Martin Ruthardt, MD, El-Nasir M A Lalani, BSc MBChB FRCPath PhDFHEA

Blood (2019) 134 (Supplement_1): 2570.

https://doi.org/10.1182/blood-2019-130898

Published: 2019

Journal Articles

Molecular Background of Double Protein Expressor B-Cell Lymphomas

Leo Meriranta, MD, Amjad Alkodsi, PhD, Annika Pasanen, MD PhD, Jari Haukka, PhD, Marja-Liisa Karjalainen-Lindsberg, MD PhD, Sirpa Leppa, MD Prof

Blood (2019) 134 (Supplement_1): 2781.

https://doi.org/10.1182/blood-2019-131220

Published: 2019

NARROW

A JAK/STAT-mediated inflammatory signaling cascade drives oncogenesis in AF10-rearranged AML

JAK/STAT pathway inhibition sensitizes CD8 T cells to dexamethasone-induced apoptosis in hyperinflammation

Gene alterations in epigenetic modifiers and JAK-STAT signaling are frequent in breast implant–associated ALCL

HDAC11 deficiency disrupts oncogene-induced hematopoiesis in myeloproliferative neoplasms

Genomic analyses of PMBL reveal new drivers and mechanisms of sensitivity to PD-1 blockade

Global Gene Expression and Mutation Signatures Are Preserved in PDX Models of Pediatric AML and Aid Discovery of Targeted Therapy for Cases with CBFA2T3/GLIS2 Rearrangement

The Clinical and Functional Relevance of the Transforming AKT E17K Mutation in T-ALL

Small Molecule-Induced, Selective STAT3 Degradation Leads to Anti-Tumor Activity in STAT3-Dependent Heme Malignancies

Stat3 Is Activated By ROS to Uniquely Regulate Primitive Erythropoiesis

Cross-Talk between Cytokine and NF-ĸb Signaling in the CLL Microenvironment Can Affect Sensitivity for Venetoclax

The Validation of the BCR/ABL1 -like Predictor across Laboratories Shows Reproducibility of Results

Mutations in Triple-Negative Patients with Myeloproliferative Neoplasms

Ruxolitinib, a JAK1/JAK2 Selective Inhibitor, Ameliorates Gastrointestinal and Cutaneous Pathogenesis in MHC-Mismatched Preclinical Models of Acute and Chronic Graft-Versus-Host Disease

Dual Driver Mutant BCR-ABL1-Negative Myeloid Neoplasms: Multicenter Clinicopathologic and Genomic Analysis

Characterization of a Novel JAK1 Pseudokinase Mutation in the First Case of Trisomy 21-Independent GATA1-Mutated Transient Abnormal Myelopoiesis

Altered Dynamics of Monocyte Subpopulations and Pro-Inflammatory Signaling Pathways in Polycythemia Vera Revealed By Mass Cytometry

Hypoxia Inducible Factors' Transcriptional Activity in Polycythemia Vera

RMC-4550, an Allosteric Inhibitor of SHP2, Displays Therapeutic Efficacy in Pre-Clinical Models of Myeloproliferative Neoplasms

Activation of AKT/mTOR Pathway in Ph+ Acute Lymphoblastic Leukemia (ALL) Leads to Non-Mutational Resistance

Molecular Background of Double Protein Expressor B-Cell Lymphomas

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American Society of Hematology

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American Society of Hematology

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